Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes

Liver International

Volumn 29, Issue 7, 2009, Pages 1010-1021

  Copple, Bryan L ^a   Bustamante, Juan J ^a   Welch, Timothy P ^a   Kim, Nam Deuk ^a,b   Moon, Jeon Ok ^a,b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b Pusan National University   (South Korea)

Author keywords

Hepatocytes; Hypoxia inducible factor; Liver fibrosis

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN 1; ADRENOMEDULLIN 2; ALANINE AMINOTRANSFERASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL HYPOXIA; CELL ISOLATION; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; DIMERIZATION; ENZYME RELEASE; EXON; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE TRANSLOCATION; HETERODIMERIZATION; LIVER CELL; LIVER FIBROSIS; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

ADRENOMEDULLIN; ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; NEUROPEPTIDES; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-SIS; RNA, MESSENGER; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67650489215     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2009.02015.x     Document Type: Article

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