메뉴 건너뛰기




Volumn 147, Issue 2, 2006, Pages 943-951

Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BIOLOGICAL MARKER; GLUCOSE REGULATED PROTEIN 78; INSULIN; LEPTIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; SATURATED FATTY ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

EID: 30944451788     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0570     Document Type: Article
Times cited : (462)

References (58)
  • 3
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P 2002 Nonalcoholic fatty liver disease. N Eng J Med 346:1221-1231
    • (2002) N Eng J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 4
    • 0036627883 scopus 로고    scopus 로고
    • Hepatic steatosis and type 2 diabetes mellitus
    • Clark J, Diehl A 2002 Hepatic steatosis and type 2 diabetes mellitus. Curr Diab Rep 2:210-215
    • (2002) Curr Diab Rep , vol.2 , pp. 210-215
    • Clark, J.1    Diehl, A.2
  • 5
    • 0842269198 scopus 로고    scopus 로고
    • Hepatic steatosis in obese patients: Clinical aspects and prognostic significance
    • Festi D, Colecchia A, Sacco T, Bondi M, Roda E, Marchesini G 2004 Hepatic steatosis in obese patients: clinical aspects and prognostic significance. Obes Rev 5:27-42
    • (2004) Obes Rev , vol.5 , pp. 27-42
    • Festi, D.1    Colecchia, A.2    Sacco, T.3    Bondi, M.4    Roda, E.5    Marchesini, G.6
  • 6
    • 0038142845 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: An underrecognized cause of cryptogenic cirrhosis
    • Clark JM, Diehl A 2003 Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. JAMA 289:3000-3004
    • (2003) JAMA , vol.289 , pp. 3000-3004
    • Clark, J.M.1    Diehl, A.2
  • 7
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • Day CP, James O 1998 Steatohepatitis: a tale of two "hits"? Gastroenterology 114:842-845
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.2
  • 10
    • 0033779714 scopus 로고    scopus 로고
    • Free fatty acids and pathogenesis of type 2 diabetes mellitus
    • Bergman RN, Ader M 2000 Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends Endocrinol Metab 11:351-356
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 351-356
    • Bergman, R.N.1    Ader, M.2
  • 11
    • 0345374579 scopus 로고    scopus 로고
    • Minireview: Weapons of lean body mass destruction: The role of ectopic lipids in the metabolic syndrome
    • Unger RH 2003 Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144:5159-5165
    • (2003) Endocrinology , vol.144 , pp. 5159-5165
    • Unger, R.H.1
  • 12
    • 0037203345 scopus 로고    scopus 로고
    • Lipoapoptosis: Its mechanism and its diseases
    • Unger RH, Orci L 2002 Lipoapoptosis: its mechanism and its diseases. Biochim Biophys Acta 1585:202-212
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 202-212
    • Unger, R.H.1    Orci, L.2
  • 13
    • 0035130102 scopus 로고    scopus 로고
    • Diseases of liporegulation: New perspective on obesity and related disorders
    • Unger RH, Orci L 2001 Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 15:312-321
    • (2001) FASEB J , vol.15 , pp. 312-321
    • Unger, R.H.1    Orci, L.2
  • 14
    • 0033692758 scopus 로고    scopus 로고
    • Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects
    • Hardy S, Langelier Y, Prentki M 2000 Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects. Cancer Res 60:6353-6358
    • (2000) Cancer Res , vol.60 , pp. 6353-6358
    • Hardy, S.1    Langelier, Y.2    Prentki, M.3
  • 15
    • 0035805629 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis can occur through a ceramide-independent pathway
    • Listenberger LL, Ory DS, Schaffer JE 2001 Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem 276:14890-14895
    • (2001) J Biol Chem , vol.276 , pp. 14890-14895
    • Listenberger, L.L.1    Ory, D.S.2    Schaffer, J.E.3
  • 17
    • 0035156817 scopus 로고    scopus 로고
    • Distinct effects of saturated and unsaturated fatty acids on B-cell turnover and function
    • Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, Donath MY 2001 Distinct effects of saturated and unsaturated fatty acids on B-cell turnover and function. Diabetes 50:69-76
    • (2001) Diabetes , vol.50 , pp. 69-76
    • Maedler, K.1    Spinas, G.A.2    Dyntar, D.3    Moritz, W.4    Kaiser, N.5    Donath, M.Y.6
  • 18
    • 0031013369 scopus 로고    scopus 로고
    • Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis
    • Paumen MB, Ishida Y, Muramatsu M, Yamamoto M, Honjo T 1997 Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J Biol Chem 272:3324-3329
    • (1997) J Biol Chem , vol.272 , pp. 3324-3329
    • Paumen, M.B.1    Ishida, Y.2    Muramatsu, M.3    Yamamoto, M.4    Honjo, T.5
  • 19
    • 0028243762 scopus 로고
    • Involvement of liver and skeletal muscle in sucrose-induced insulin resistance: Dose-response studies
    • Pagliassotti MJ, Shahrokhi KA, Moscarello M 1994 Involvement of liver and skeletal muscle in sucrose-induced insulin resistance: dose-response studies. Am J Physiol 266:R1637-R1644
    • (1994) Am J Physiol , vol.266
    • Pagliassotti, M.J.1    Shahrokhi, K.A.2    Moscarello, M.3
  • 21
    • 0029987520 scopus 로고    scopus 로고
    • Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats
    • Pagliassotti MJ, Prach PA, Koppenhafer TA, Pan DA 1996 Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats. Am J Physiol 271:R1319-R1326
    • (1996) Am J Physiol , vol.271
    • Pagliassotti, M.J.1    Prach, P.A.2    Koppenhafer, T.A.3    Pan, D.A.4
  • 22
    • 0001383016 scopus 로고
    • Permanent cannulation of aorta and vena cava in rats and ground squirrels
    • Popovic V, Popovic P 1960 Permanent cannulation of aorta and vena cava in rats and ground squirrels. J Appl Physiol 15:727-728
    • (1960) J Appl Physiol , vol.15 , pp. 727-728
    • Popovic, V.1    Popovic, P.2
  • 24
    • 0023245416 scopus 로고
    • Estimation of endogenous glucose production during hyperinsulinemic- euglycemic glucose clamps: Comparison of unlabeled and labeled exogenous glucose infusates
    • Finegood DT, Bergman RN, Vranic M 1987 Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps: comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 36:914-924
    • (1987) Diabetes , vol.36 , pp. 914-924
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 25
    • 0001276586 scopus 로고
    • Restoration of the liver of the white rat following partical surgical removal
    • Higgins GM, Anderson RM 1931 Restoration of the liver of the white rat following partical surgical removal. Arch Pathol 12:656-665
    • (1931) Arch Pathol , vol.12 , pp. 656-665
    • Higgins, G.M.1    Anderson, R.M.2
  • 26
    • 0014645531 scopus 로고
    • High-yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structural study
    • Berry M, Friend D 1969 High-yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structural study. J Cell Biol 43:506-519
    • (1969) J Cell Biol , vol.43 , pp. 506-519
    • Berry, M.1    Friend, D.2
  • 28
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ 1985 A rapid method of total lipid extraction and purification. Can J Physiol 37:911-917
    • (1985) Can J Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 29
    • 0001457369 scopus 로고
    • The role of polyamines in neutralization of bacteriophage deoxyribonucleic acid
    • Ames BN, Dubin DT 1960 The role of polyamines in neutralization of bacteriophage deoxyribonucleic acid. J Biol Chem 235:769-775
    • (1960) J Biol Chem , vol.235 , pp. 769-775
    • Ames, B.N.1    Dubin, D.T.2
  • 31
    • 0037224421 scopus 로고    scopus 로고
    • Glucose-6-phosphatase activity is not suppressed but the mRNA level is increased by a sucrose-enriched meal in rats
    • Pagliassotti MJ, Wei Y, Bizeau ME 2003 Glucose-6-phosphatase activity is not suppressed but the mRNA level is increased by a sucrose-enriched meal in rats. J Nutr 133:32-37
    • (2003) J Nutr , vol.133 , pp. 32-37
    • Pagliassotti, M.J.1    Wei, Y.2    Bizeau, M.E.3
  • 34
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman RJ 2002 Orchestrating the unfolded protein response in health and disease. J Clin Invest 110:1389-1398
    • (2002) J Clin Invest , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 35
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ 2002 IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16:452-466
    • (2002) Genes Dev , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5    Okada, T.6    Yoshida, H.7    Mori, K.8    Kaufman, R.J.9
  • 39
    • 9644303176 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
    • Gu F, Nguyen DT, Stuible M, Dube N, Tremblay ML, Chevet E 2004 Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress. J Biol Chem 279:49689-49693
    • (2004) J Biol Chem , vol.279 , pp. 49689-49693
    • Gu, F.1    Nguyen, D.T.2    Stuible, M.3    Dube, N.4    Tremblay, M.L.5    Chevet, E.6
  • 42
    • 0033985856 scopus 로고    scopus 로고
    • Failure of regeneration of the steatotic rat liver: Disruption at two different levels in the regeneration pathway
    • Selzner M, Clavien PA 2000 Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway. Hepatology 31:35-42
    • (2000) Hepatology , vol.31 , pp. 35-42
    • Selzner, M.1    Clavien, P.A.2
  • 45
    • 0034812914 scopus 로고    scopus 로고
    • Disrupted signaling and inhibited regeneration in obese mice with fatty livers: Implications for nonalcoholic fatty liver disease pathophysiology
    • Yang SQ, Lin HZ, Mandal AK, Huang J, Diehl AM 2001 Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology. Hepatology 34:694-706
    • (2001) Hepatology , vol.34 , pp. 694-706
    • Yang, S.Q.1    Lin, H.Z.2    Mandal, A.K.3    Huang, J.4    Diehl, A.M.5
  • 46
    • 0032934176 scopus 로고    scopus 로고
    • Does steatohepatitis impair liver regeneration? A study in a dietary model of non-alcoholic steatohepatitis in rats
    • Zhang BH, Weltman M, Farrell GC 1999 Does steatohepatitis impair liver regeneration? A study in a dietary model of non-alcoholic steatohepatitis in rats. J Gastroenterol Hepatol 14:133-137
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 133-137
    • Zhang, B.H.1    Weltman, M.2    Farrell, G.C.3
  • 48
    • 0034968330 scopus 로고    scopus 로고
    • Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival
    • Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D 2001 Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 7:1153-1163
    • (2001) Mol Cell , vol.7 , pp. 1153-1163
    • Harding, H.P.1    Zeng, H.2    Zhang, Y.3    Jungries, R.4    Chung, P.5    Plesken, H.6    Sabatini, D.D.7    Ron, D.8
  • 49
    • 0036175128 scopus 로고    scopus 로고
    • Targeted disruption of the Chop gene delays endoplasmic reticulum-stress mediated diabetes
    • Oyadomari S, Koizumi A, Takeda K, Gotoh, T, Akira S, Araki E, Mori M 2002 Targeted disruption of the Chop gene delays endoplasmic reticulum-stress mediated diabetes. J Clin Invest 109:525-532
    • (2002) J Clin Invest , vol.109 , pp. 525-532
    • Oyadomari, S.1    Koizumi, A.2    Takeda, K.3    Gotoh, T.4    Akira, S.5    Araki, E.6    Mori, M.7
  • 50
    • 0030040689 scopus 로고    scopus 로고
    • Regulation of organelle biogenesis
    • Nunnari J, Walter P 1996 Regulation of organelle biogenesis. Cell 84:389-394
    • (1996) Cell , vol.84 , pp. 389-394
    • Nunnari, J.1    Walter, P.2
  • 51
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman RJ 1999 Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13:1211-1233
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 53
    • 0032779694 scopus 로고    scopus 로고
    • Signal transduction from the endoplasmic reticulum to the cell nucleus
    • Pahl HL 1999 Signal transduction from the endoplasmic reticulum to the cell nucleus. Physiol Rev 79:683-701
    • (1999) Physiol Rev , vol.79 , pp. 683-701
    • Pahl, H.L.1
  • 54
    • 0036856008 scopus 로고    scopus 로고
    • Translational control in the endoplasmic reticulum stress response
    • Ron D 2002 Translational control in the endoplasmic reticulum stress response. J Clin Invest 110:1383-1388
    • (2002) J Clin Invest , vol.110 , pp. 1383-1388
    • Ron, D.1
  • 55
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • Hu P, Han Z, Couvillon AD, Exton JH 2004 Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem 279:49420-49429
    • (2004) J Biol Chem , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 57
    • 1242336980 scopus 로고    scopus 로고
    • Apoptosis: The nexus of liver injury and fibrosis
    • Canbay A, Friedman S, Gores GJ 2004 Apoptosis: the nexus of liver injury and fibrosis. Hepatology 39:273-278
    • (2004) Hepatology , vol.39 , pp. 273-278
    • Canbay, A.1    Friedman, S.2    Gores, G.J.3
  • 58
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ 2005 Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.