-
1
-
-
0033083111
-
IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells
-
Aarvak T, Chabaud M, Miossec P, Natvig JB. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol 1999; 162: 1246-51.
-
(1999)
J Immunol
, vol.162
, pp. 1246-1251
-
-
Aarvak, T.1
Chabaud, M.2
Miossec, P.3
Natvig, J.B.4
-
2
-
-
0000050472
-
A nerve growthstimulating factor isolated from sarcomas 37 and 180
-
Cohen S, Levi-Montalcini R, Hamburger V. A nerve growthstimulating factor isolated from sarcomas 37 and 180. PNAS 1954; 40: 1014-8.
-
(1954)
PNAS
, vol.40
, pp. 1014-1018
-
-
Cohen, S.1
Levi-Montalcini, R.2
Hamburger, V.3
-
4
-
-
33845772515
-
Interferon-like virus-inhibitor induced in human leukocytes by phytohemagglutinin
-
Wheelock EF. Interferon-like virus-inhibitor induced in human leukocytes by phytohemagglutinin. Science 1965; 149: 310-1.
-
(1965)
Science
, vol.149
, pp. 310-311
-
-
Wheelock, E.F.1
-
5
-
-
0013923944
-
Delayed hypersensitivity in vitro: Its mediation by cell-free substances formed by lymphoid cell-antigen interaction
-
David JR. Delayed hypersensitivity in vitro: Its mediation by cell-free substances formed by lymphoid cell-antigen interaction. PNAS 1966; 56: 72-7.
-
(1966)
PNAS
, vol.56
, pp. 72-77
-
-
David, J.R.1
-
6
-
-
0013933261
-
Mechanism of a reaction in vitro associated with delayed-type hypersensitivity
-
Bloom BR, Bennett B. Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science 1966; 153: 80-2.
-
(1966)
Science
, vol.153
, pp. 80-82
-
-
Bloom, B.R.1
Bennett, B.2
-
7
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell EA, Old LJ, Kassel RL, Fiore N, Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. PNAS 1975; 72: 3666-70.
-
(1975)
PNAS
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Fiore, N.4
Williamson, B.5
-
8
-
-
0017199306
-
Selective in vitro growth of T lymphocytes from normal human bone marrows
-
Morgan DA, Ruscetti FW, Gallo RC. Selective in vitro growth of T lymphocytes from normal human bone marrows. Science 1976; 193: 1007-8
-
(1976)
Science
, vol.193
, pp. 1007-1008
-
-
Morgan, D.A.1
Ruscetti, F.W.2
Gallo, R.C.3
-
9
-
-
0037119351
-
Cytokine and cytokine receptor pleiotropy and redundancy
-
Ozaki K, Leonard WJ. Cytokine and cytokine receptor pleiotropy and redundancy. J Biol Chem 2002; 277: 29355-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 29355-29358
-
-
Ozaki, K.1
Leonard, W.J.2
-
10
-
-
0022640843
-
Two types of murine helper T cell clone
-
Mosmann TR. Two types of murine helper T cell clone. J Immunol 1986; 136: 2348-57.
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
-
11
-
-
0019375989
-
Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation
-
Jasin HE, Dingle JT. Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation. J Clin Invest 1981; 68: 571-81.
-
(1981)
J Clin Invest
, vol.68
, pp. 571-581
-
-
Jasin, H.E.1
Dingle, J.T.2
-
12
-
-
0021215624
-
In vitro activation of human chondrocytes and synoviocytes by a human interleukin-1-like factor
-
McGuire-Goldring MB, Meats JE, Wood DD, Ihrie EJ, Ebsworth NM, Russell RG. In vitro activation of human chondrocytes and synoviocytes by a human interleukin-1-like factor. Arthritis Rheum 1984; 27: 654-62
-
(1984)
Arthritis Rheum
, vol.27
, pp. 654-662
-
-
McGuire-Goldring, M.B.1
Meats, J.E.2
Wood, D.D.3
Ihrie, E.J.4
Ebsworth, N.M.5
Russell, R.G.6
-
13
-
-
0345214235
-
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1)
-
Mizel SB, Dayer J-M, Krane SM, Mergenhagen SE. Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). PNAS 1981; 78: 2474-7.
-
(1981)
PNAS
, vol.78
, pp. 2474-2477
-
-
Mizel, S.B.1
Dayer, J.-M.2
Krane, S.M.3
Mergenhagen, S.E.4
-
14
-
-
0020323211
-
Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis
-
Fontana A, Hengartner H, Weber E, Fehr K, Grob P, Cohen G. Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int 1982; 2: 49-53.
-
(1982)
Rheumatol Int
, vol.2
, pp. 49-53
-
-
Fontana, A.1
Hengartner, H.2
Weber, E.3
Fehr, K.4
Grob, P.5
Cohen, G.6
-
15
-
-
0021358538
-
Cytokines and the chronic inflammation of rheumatic disease. I. The presence of interleukin-1 in synovial fluids
-
Nouri AME, Panayi GS, Goodman SM. Cytokines and the chronic inflammation of rheumatic disease. I. The presence of interleukin-1 in synovial fluids. Clin Exp Immunol 1984; 55: 295-302.
-
(1984)
Clin Exp Immunol
, vol.55
, pp. 295-302
-
-
Nouri, A.M.E.1
Panayi, G.S.2
Goodman, S.M.3
-
16
-
-
0022441214
-
Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage
-
Saklatvala J. Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 1986; 322: 547-9.
-
(1986)
Nature
, vol.322
, pp. 547-549
-
-
Saklatvala, J.1
-
17
-
-
0024063321
-
Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis
-
Husby G, Williams RJ. Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis. J Autoimmun 1988; 1: 363-71.
-
(1988)
J Autoimmun
, vol.1
, pp. 363-371
-
-
Husby, G.1
Williams, R.J.2
-
18
-
-
0033179534
-
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis
-
Charles P, Elliott MJ, Davis D, Potter A, Kalden JR, Antoni CE, et al. Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J Immunol 1999; 163: 1521-8.
-
(1999)
J Immunol
, vol.163
, pp. 1521-1528
-
-
Charles, P.1
Elliott, M.J.2
Davis, D.3
Potter, A.4
Kalden, J.R.5
Antoni, C.E.6
-
19
-
-
0030022275
-
The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis
-
McInnes IB, Al-Mughales J, Field M, Leung BP, Huang F-P, Dixon R, et al. The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nat Med 1996; 2: 175-82.
-
(1996)
Nat Med
, vol.2
, pp. 175-182
-
-
McInnes, I.B.1
Al-Mughales, J.2
Field, M.3
Leung, B.P.4
Huang, F.-P.5
Dixon, R.6
-
20
-
-
0031042456
-
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis
-
McInnes IB, Leung BP, Sturrock RD, Field M, Liew FY. Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Nat Med 1997; 3: 189-95.
-
(1997)
Nat Med
, vol.3
, pp. 189-195
-
-
McInnes, I.B.1
Leung, B.P.2
Sturrock, R.D.3
Field, M.4
Liew, F.Y.5
-
21
-
-
0031884806
-
Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis
-
McInnes IB, Liew FY. Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis. Immunol Today 1998; 19: 75-9.
-
(1998)
Immunol Today
, vol.19
, pp. 75-79
-
-
McInnes, I.B.1
Liew, F.Y.2
-
22
-
-
57449116787
-
Interleukin-15 stimulated macrophages to activate CD4+ T cells: A role in the pathogenesis of rheumatoid arthritis?
-
Rückert R, Brandt K, Ernst M, Marienfeld K, Metzler C, Budagian V, et al. Interleukin-15 stimulated macrophages to activate CD4+ T cells: A role in the pathogenesis of rheumatoid arthritis? Immunology 2009; 126: 63-73.
-
(2009)
Immunology
, vol.126
, pp. 63-73
-
-
Rückert, R.1
Brandt, K.2
Ernst, M.3
Marienfeld, K.4
Metzler, C.5
Budagian, V.6
-
23
-
-
0024269961
-
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis
-
Hirano T, Matsuda T, Turner M, Miyasaka N, Buchan G, Tang B, et al. Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol 1988; 18: 1797-801.
-
(1988)
Eur J Immunol
, vol.18
, pp. 1797-1801
-
-
Hirano, T.1
Matsuda, T.2
Turner, M.3
Miyasaka, N.4
Buchan, G.5
Tang, B.6
-
24
-
-
0023942493
-
Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
-
Houssiau FA, Devogelaer JP, Van Damme J, de Deuxchaisnes CN, Van Snick J. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum 1988; 31: 784-8.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 784-788
-
-
Houssiau, F.A.1
Devogelaer, J.P.2
Van Damme, J.3
de Deuxchaisnes, C.N.4
Van Snick, J.5
-
25
-
-
0024353712
-
IL-6 is the principal factor produced by synovia of patients with rheumatoid arthritis that induces B-lymphocytes to secrete immunoglobulins. Ann N Y
-
Nawata Y, Eugui EM, Lee SW, A llison AC. IL-6 is the principal factor produced by synovia of patients with rheumatoid arthritis that induces B-lymphocytes to secrete immunoglobulins. Ann N Y Acad Sci 1989; 557: 230-8.
-
(1989)
Acad Sci
, vol.557
, pp. 230-238
-
-
Nawata, Y.1
Eugui, E.M.2
Lee, S.W.3
llison AC, A.4
-
26
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, Korn TS, T.B, Oukka M, Weiner HL, et al. Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 2006; 441: 235-8.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn4
TS, T.B.5
Oukka, M.6
Weiner, H.L.7
-
27
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006; 441: 231-4.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
-
28
-
-
20144362101
-
Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis
-
Yokota S, Miyamae T, Imagawa T, Iwata N, Katakura S, Mori M, et al. Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis and Rheumatism 2005; 52: 818- 25.
-
Arthritis and Rheumatism 2005; 52: 818- 25
-
-
Yokota, S.1
Miyamae, T.2
Imagawa, T.3
Iwata, N.4
Katakura, S.5
Mori, M.6
-
29
-
-
34547514211
-
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells
-
Kimura A, Naka T, Kishimoto T. IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells. PNAS 2007; 104: 12099-104.
-
(2007)
PNAS
, vol.104
, pp. 12099-12104
-
-
Kimura, A.1
Naka, T.2
Kishimoto, T.3
-
30
-
-
0029034038
-
Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice
-
Germann TS, Jacek, Hess H, Störkel S, Podlaski FJ, Gately MK, Schmitt E, et al. Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice. PNAS 1995; 92: 4823-7.
-
(1995)
PNAS
, vol.92
, pp. 4823-4827
-
-
Germann, T.S.1
Jacek2
Hess, H.3
Störkel, S.4
Podlaski, F.J.5
Gately, M.K.6
Schmitt, E.7
-
31
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan TK, Kastelein RA, et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 2003; 198: 1951-7
-
(2003)
J Exp Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.K.5
Kastelein, R.A.6
-
32
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999; 103: 1345-52.
-
(1999)
J Clin Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
-
33
-
-
0037371262
-
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kB Ligand/Osteoprotegerin balance
-
Lubberts E, van den Bersselaar L, Oppers-Walgreen B, Schwarzenberger P, Coenen-de Roo CJJK, Jay K, et al. IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kB Ligand/Osteoprotegerin balance. J Immunol 2003; 170: 2655-62.
-
(2003)
J Immunol
, vol.170
, pp. 2655-2662
-
-
Lubberts, E.1
van den Bersselaar, L.2
Oppers-Walgreen, B.3
Schwarzenberger, P.4
Coenen-de Roo, C.J.J.K.5
Jay, K.6
-
34
-
-
0038623916
-
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
-
Nakae S, Saijo S, Horai R, Sudo K, Mori S, Iwakura Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. PNAS 2003; 100: 5986-90.
-
(2003)
PNAS
, vol.100
, pp. 5986-5990
-
-
Nakae, S.1
Saijo, S.2
Horai, R.3
Sudo, K.4
Mori, S.5
Iwakura, Y.6
-
35
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6: 1123-32.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
-
36
-
-
42949133377
-
-
Romagnani S. Human Th17 cells. Arthritis Res Ther 2008; 10: Epub.
-
Romagnani S. Human Th17 cells. Arthritis Res Ther 2008; 10: Epub.
-
-
-
-
37
-
-
68449097516
-
-
Allan RN, Jonathan MR, Hanauer SB Ed, New York, Churchill Livingstone
-
Hodgson HJF. In: Allan RN, Jonathan MR, Hanauer SB Ed, Inflamm Bowel Dis. New York, Churchill Livingstone. 1997, 343-7.
-
(1997)
Inflamm Bowel Dis
, pp. 343-347
-
-
Hodgson, H.J.F.1
-
38
-
-
0021637875
-
Macrophage activation, chronic inflammation and gastrointestinal disease
-
Tanner AR, Arthur MJ, Wright R. Macrophage activation, chronic inflammation and gastrointestinal disease. Gut 1984; 25: 760-83.
-
(1984)
Gut
, vol.25
, pp. 760-783
-
-
Tanner, A.R.1
Arthur, M.J.2
Wright, R.3
-
39
-
-
0022387257
-
Cytokine production in inflammatory bowel disease
-
Miura M, Hiwatashi N. Cytokine production in inflammatory bowel disease. J Clin Lab Immunol 1985; 18: 81-6.
-
(1985)
J Clin Lab Immunol
, vol.18
, pp. 81-86
-
-
Miura, M.1
Hiwatashi, N.2
-
40
-
-
0024344814
-
Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis or Crohn's disease
-
Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis or Crohn's disease. Gut 1989; 30: 835-8.
-
(1989)
Gut
, vol.30
, pp. 835-838
-
-
Mahida, Y.R.1
Wu, K.2
Jewell, D.P.3
-
41
-
-
0026717902
-
Cytokine production in patients with inflammatory bowel disease
-
Nakamura M, Saito H, Kasanuki J, Tamura Y, Yoshida S. Cytokine production in patients with inflammatory bowel disease. Gut 1992; 33: 933-7.
-
(1992)
Gut
, vol.33
, pp. 933-937
-
-
Nakamura, M.1
Saito, H.2
Kasanuki, J.3
Tamura, Y.4
Yoshida, S.5
-
42
-
-
0025442212
-
Role of interleukin 1 in inflammatory bowel disease-enhanced production during active disease
-
Ligumsky M, Simon PL, Karmeli F, Rachmilewitz D. Role of interleukin 1 in inflammatory bowel disease-enhanced production during active disease. Gut 1990; 31: 686-9.
-
(1990)
Gut
, vol.31
, pp. 686-689
-
-
Ligumsky, M.1
Simon, P.L.2
Karmeli, F.3
Rachmilewitz, D.4
-
43
-
-
0026336617
-
Colonic mucosa interleukin-6 in inflammatory bowel disease
-
Mitsuyama K, Sasaki E, Toyonaga A, Ikeda H, Tsuruta O, Irie A, et al. Colonic mucosa interleukin-6 in inflammatory bowel disease. Digestion 1991; 50: 104-11.
-
(1991)
Digestion
, vol.50
, pp. 104-111
-
-
Mitsuyama, K.1
Sasaki, E.2
Toyonaga, A.3
Ikeda, H.4
Tsuruta, O.5
Irie, A.6
-
44
-
-
0026689516
-
Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease. Dig
-
Stevens C, Walz G, Singaram C, Lipman ML, Zanker BM, A, Antonioli D, et al. Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease. Dig Dis Sci 1992; 37: 818-26.
-
(1992)
Dis Sci
, vol.37
, pp. 818-826
-
-
Stevens, C.1
Walz, G.2
Singaram, C.3
Lipman, M.L.4
Zanker5
BM, A.6
Antonioli, D.7
-
45
-
-
0027451455
-
Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
-
Reinecker H-C, Steffen M, Witthoeft T, Pflueger I, Schreiber S, MacDermott RP, et al. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993; 94: 174-81.
-
(1993)
Clin Exp Immunol
, vol.94
, pp. 174-181
-
-
Reinecker, H.-C.1
Steffen, M.2
Witthoeft, T.3
Pflueger, I.4
Schreiber, S.5
MacDermott, R.P.6
-
46
-
-
0026780966
-
Serum tumor necrosis factor activity in inflammatory bowel disease
-
Maeda M, Watanabe N, Neda H, Yamauchi N, Okamoto T, Sasaki H, et al. Serum tumor necrosis factor activity in inflammatory bowel disease. Immunopharmacol Immunotoxicol 1992; 14: 451-61.
-
(1992)
Immunopharmacol Immunotoxicol
, vol.14
, pp. 451-461
-
-
Maeda, M.1
Watanabe, N.2
Neda, H.3
Yamauchi, N.4
Okamoto, T.5
Sasaki, H.6
-
47
-
-
0026589748
-
Enhanced mucosal cytokine production in inflammatory bowel disease
-
Pullman WE, Elsbury S, Kobayashi M, Hapel AJ, F. DW. Enhanced mucosal cytokine production in inflammatory bowel disease. Gastroenterology 1992; 102: 529-37.
-
(1992)
Gastroenterology
, vol.102
, pp. 529-537
-
-
Pullman, W.E.1
Elsbury, S.2
Kobayashi, M.3
Hapel, A.J.4
DW, F.5
-
48
-
-
0028898529
-
-
Casini-Raggi VK, L, Chong YJ, Fiocchi C, Pizarro TT, Cominelli F. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol 1995; 154: 2434-40.
-
Casini-Raggi VK, L, Chong YJ, Fiocchi C, Pizarro TT, Cominelli F. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol 1995; 154: 2434-40.
-
-
-
-
49
-
-
0029586031
-
Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
-
Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Meyer Zum Büschenfelde KH. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995; 102: 448-55.
-
(1995)
Clin Exp Immunol
, vol.102
, pp. 448-455
-
-
Duchmann, R.1
Kaiser, I.2
Hermann, E.3
Mayet, W.4
Ewe, K.5
Meyer Zum6
Büschenfelde, K.H.7
-
50
-
-
0032718352
-
Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice
-
Fuss IJ, Marth T, Neurath MF, Pearlstein GR, Jain A, Strober W. Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice. Gastroenterology 1999; 117: 1078-88.
-
(1999)
Gastroenterology
, vol.117
, pp. 1078-1088
-
-
Fuss, I.J.1
Marth, T.2
Neurath, M.F.3
Pearlstein, G.R.4
Jain, A.5
Strober, W.6
-
51
-
-
0035877257
-
Ubiquituous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
Wiekowski MT, Leach MW, Evans EW, Sullivan L, Chen SC, Vassileva G, et al. Ubiquituous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J Immunol 2001; 166: 7563-70.
-
J Immunol 2001
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
-
52
-
-
0038744423
-
Colonic lamina propria dendritic cells in mice with CD4+ T cell-induced colitis
-
Krajina T, Leithäuser F, Möller P, Trobonjaca Z, Reimann J. Colonic lamina propria dendritic cells in mice with CD4+ T cell-induced colitis. Eur J Immunol 2003; 33: 1073-83.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1073-1083
-
-
Krajina, T.1
Leithäuser, F.2
Möller, P.3
Trobonjaca, Z.4
Reimann, J.5
-
53
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan TK, McKenzie B, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006; 116: 1310-6.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.K.5
McKenzie, B.6
-
54
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, Araki Y, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 2003; 52: 65-70.
-
(2003)
Gut
, vol.52
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
-
55
-
-
0021191999
-
Astrocytes present myelin basic protein to encephalitogenic T-cell lines
-
Fontana A, Fierz W, Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature 1984; 307: 273-6.
-
(1984)
Nature
, vol.307
, pp. 273-276
-
-
Fontana, A.1
Fierz, W.2
Wekerle, H.3
-
56
-
-
0026707402
-
Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
-
Kennedy MK, Torrance DS, Picha KS, Mohler KM. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 1992; 149: 2496-505.
-
(1992)
J Immunol
, vol.149
, pp. 2496-2505
-
-
Kennedy, M.K.1
Torrance, D.S.2
Picha, K.S.3
Mohler, K.M.4
-
57
-
-
0027331778
-
Demonstration of interleukin-1 beta in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultra-structural level
-
Bauer J, Berkenbosch F, Van Dam A, Dijkstra C. Demonstration of interleukin-1 beta in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultra-structural level. J Neuroimmunol 1993; 48: 13-21.
-
(1993)
J Neuroimmunol
, vol.48
, pp. 13-21
-
-
Bauer, J.1
Berkenbosch, F.2
Van Dam, A.3
Dijkstra, C.4
-
58
-
-
0030789773
-
Cortical protection by localized striatal injection of IL-1RA following cerebral ischemia in the rat
-
Stroemer RP, Rothwell NJ. Cortical protection by localized striatal injection of IL-1RA following cerebral ischemia in the rat. J Cereb Blood Flow Metab 1997; 17: 597-604.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 597-604
-
-
Stroemer, R.P.1
Rothwell, N.J.2
-
59
-
-
34249809700
-
A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis
-
Spohn G, Guler R, Johansen P, Keller I, Jacobs M, Beck M, et al. A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis. J Immunol 2007; 178: 7450-7.
-
(2007)
J Immunol
, vol.178
, pp. 7450-7457
-
-
Spohn, G.1
Guler, R.2
Johansen, P.3
Keller, I.4
Jacobs, M.5
Beck, M.6
-
61
-
-
0028941871
-
The adhesion molecule and cytokine profile of multiple sclerosis lesions
-
Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 1995; 37: 424-35.
-
(1995)
Ann Neurol
, vol.37
, pp. 424-435
-
-
Cannella, B.1
Raine, C.S.2
-
62
-
-
0025999081
-
Human tumor necrosis factor-alpha augments experimental allergic encephalomyelitis in rats
-
Kuroda Y, Shimamoto Y. Human tumor necrosis factor-alpha augments experimental allergic encephalomyelitis in rats. J Neuro-immunol 1991; 34: 159-64.
-
(1991)
J Neuro-immunol
, vol.34
, pp. 159-164
-
-
Kuroda, Y.1
Shimamoto, Y.2
-
63
-
-
0028806468
-
Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: Dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor alpha and tumor necrosis factor beta
-
Issazadeh S, Ljungdahl A, Höjeberg B, Mustafa M, Olsson T. Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: Dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor alpha and tumor necrosis factor beta. J Neuro-immunol 1995; 61: 205-12.
-
(1995)
J Neuro-immunol
, vol.61
, pp. 205-212
-
-
Issazadeh, S.1
Ljungdahl, A.2
Höjeberg, B.3
Mustafa, M.4
Olsson, T.5
-
64
-
-
0031916192
-
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
-
Liu J, Marino MWW, Grace, Grail D, Dunn A, Bettadapura J, Slavin AJ, et al. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nat Med 1998; 4: 78-83.
-
(1998)
Nat Med
, vol.4
, pp. 78-83
-
-
Liu, J.1
Marino, M.W.W.2
Grace3
Grail, D.4
Dunn, A.5
Bettadapura, J.6
Slavin, A.J.7
-
65
-
-
0029316962
-
Experimental autoimmune encephalomyelitis: Immunotherapy with anti-tumor necrosis factor antibodies and soluble tumor necrosis factor receptors
-
Selmaj K, Raine CS. Experimental autoimmune encephalomyelitis: immunotherapy with anti-tumor necrosis factor antibodies and soluble tumor necrosis factor receptors. Neurology 1995; 45: S44-9.
-
(1995)
Neurology
, vol.45
-
-
Selmaj, K.1
Raine, C.S.2
-
66
-
-
0023221133
-
Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
-
Panitch H, Hirsch R, Schindler J, Johnson K. Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system. Neurology 1987; 37: 1097-102.
-
(1987)
Neurology
, vol.37
, pp. 1097-1102
-
-
Panitch, H.1
Hirsch, R.2
Schindler, J.3
Johnson, K.4
-
67
-
-
0028288512
-
Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SL/J mice
-
Renno T, Lin JY, Piccirillo C, Antel J, Owens T. Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SL/J mice. J Neuroimmunol 1994; 49: 1-7.
-
(1994)
J Neuroimmunol
, vol.49
, pp. 1-7
-
-
Renno, T.1
Lin, J.Y.2
Piccirillo, C.3
Antel, J.4
Owens, T.5
-
68
-
-
0032419459
-
Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE
-
Renno T, Taupin V, Bourbonnière L, Verge G, Tran EH, De Simone R, et al. Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Mol Cell Neurosci 1998; 12: 376-89.
-
(1998)
Mol Cell Neurosci
, vol.12
, pp. 376-389
-
-
Renno, T.1
Taupin, V.2
Bourbonnière, L.3
Verge, G.4
Tran, E.H.5
De Simone, R.6
-
69
-
-
0036893601
-
Low interferon gamma producers are better treatment responders: A two-year follow-up of interferon beta-treated multiple sclerosis patients
-
Petereit HF, Nolden S, Schoppe S, Bamborschke S, Pukrop R, Heiss WD. Low interferon gamma producers are better treatment responders: A two-year follow-up of interferon beta-treated multiple sclerosis patients. Mult Scler 2002; 8: 492-4.
-
(2002)
Mult Scler
, vol.8
, pp. 492-494
-
-
Petereit, H.F.1
Nolden, S.2
Schoppe, S.3
Bamborschke, S.4
Pukrop, R.5
Heiss, W.D.6
-
70
-
-
0029957071
-
Interferon-gamma confers resistance to experimental allergic encephalomyelitis
-
Krakowski M, Owens T. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur J Immunol 1996; 26: 1641-6.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1641-1646
-
-
Krakowski, M.1
Owens, T.2
-
71
-
-
0034162486
-
IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines
-
Tran EH, Prince EN, Owens T. IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines. J Immunol 2000; 164: 2759-69.
-
(2000)
J Immunol
, vol.164
, pp. 2759-2769
-
-
Tran, E.H.1
Prince, E.N.2
Owens, T.3
-
72
-
-
0028170342
-
Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains
-
Duong TT, Finkelman FD, Singh BS, G. H. Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains. J Neuroimmunol 1994; 53: 101-7.
-
(1994)
J Neuroimmunol
, vol.53
, pp. 101-107
-
-
Duong, T.T.1
Finkelman, F.D.2
Singh, B.G.H.3
-
73
-
-
0029671318
-
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
-
Ferber IA, Brocke S, Taylor-Edwards C, Ridgway W, Dinisco C, Steinman L, et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996; 156: 5-7.
-
(1996)
J Immunol
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
Ridgway, W.4
Dinisco, C.5
Steinman, L.6
-
74
-
-
0030944709
-
Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat
-
Smith T, Hewson AK, Kingsley CI, Leonard JP, Cuzner ML. Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat. Am J Pathol 1997; 150: 1909-17.
-
(1997)
Am J Pathol
, vol.150
, pp. 1909-1917
-
-
Smith, T.1
Hewson, A.K.2
Kingsley, C.I.3
Leonard, J.P.4
Cuzner, M.L.5
-
75
-
-
0028809507
-
Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
-
Windhagen A, Newcombe J, Dangond F, Strand C, Woodroofe MN, Cuzner ML, et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med 1995; 182: 1985-96.
-
(1995)
J Exp Med
, vol.182
, pp. 1985-1996
-
-
Windhagen, A.1
Newcombe, J.2
Dangond, F.3
Strand, C.4
Woodroofe, M.N.5
Cuzner, M.L.6
-
76
-
-
0031800907
-
Interleukin-12 and perforin mRNA expression is augmented in blood mononuclear cells in multiple sclerosis
-
Matusevicius D, Kivisäkk P, Navikas V, Söderström M, Fredrikson S, Link H. Interleukin-12 and perforin mRNA expression is augmented in blood mononuclear cells in multiple sclerosis. Scand J Immunol 1998; 47: 582-90.
-
(1998)
Scand J Immunol
, vol.47
, pp. 582-590
-
-
Matusevicius, D.1
Kivisäkk, P.2
Navikas, V.3
Söderström, M.4
Fredrikson, S.5
Link, H.6
-
77
-
-
0037114150
-
IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: Evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination
-
Gran B, Zhang G-X, Yu S, Li J, Chen X-H, Ventura ES, et al. IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: Evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J Immunol 2002; 169: 7104-10.
-
(2002)
J Immunol
, vol.169
, pp. 7104-7110
-
-
Gran, B.1
Zhang, G.-X.2
Yu, S.3
Li, J.4
Chen, X.-H.5
Ventura, E.S.6
-
78
-
-
0034234528
-
IFN-beta-1b inhibits IL-12 production in peripheral blood mononuclear cells in an IL-10-dependent mechanism: Relevance to IFN-beta-1b therapeutic effects in multiple sclerosis
-
Wang X, Chen M, Wandinger KP, Williams G, Dhib-Jalbut S. IFN-beta-1b inhibits IL-12 production in peripheral blood mononuclear cells in an IL-10-dependent mechanism: Relevance to IFN-beta-1b therapeutic effects in multiple sclerosis. J Immunol 2000; 165: 548-57.
-
(2000)
J Immunol
, vol.165
, pp. 548-557
-
-
Wang, X.1
Chen, M.2
Wandinger, K.P.3
Williams, G.4
Dhib-Jalbut, S.5
-
79
-
-
0035796770
-
Oral salbutamol decrases in IL-12 in patients with secondary progressive multiple sclerosis
-
Makhlouf K, Comabella M, Imitola J, Weiner HL, Khoury SJ. Oral salbutamol decrases in IL-12 in patients with secondary progressive multiple sclerosis. J Neuroimmunol 2001; 117: 156-65.
-
(2001)
J Neuroimmunol
, vol.117
, pp. 156-165
-
-
Makhlouf, K.1
Comabella, M.2
Imitola, J.3
Weiner, H.L.4
Khoury, S.J.5
-
80
-
-
0032975730
-
Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
-
van Boxel-Dezaire AHH, Hoff SCJ, van Oosten BW, Verweij CL, Dräger AM, Adèr HJvH, J. C, et al. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol 1999; 45: 695-703.
-
(1999)
Ann Neurol
, vol.45
, pp. 695-703
-
-
van Boxel-Dezaire, A.H.H.1
Hoff, S.C.J.2
van Oosten, B.W.3
Verweij, C.L.4
Dräger, A.M.5
Adèr HJvH, J.C.6
-
81
-
-
0036677420
-
Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
-
Becher B, Durell BG, Noelle RJ. Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. J Clin Invest 2002; 110: 493-7.
-
(2002)
J Clin Invest
, vol.110
, pp. 493-497
-
-
Becher, B.1
Durell, B.G.2
Noelle, R.J.3
-
82
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233-40.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
-
83
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius D, Kivisäkk P, He B, Kostulas N, Ozenci V, Fredrikson S, et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999; 5: 101-4.
-
(1999)
Mult Scler
, vol.5
, pp. 101-104
-
-
Matusevicius, D.1
Kivisäkk, P.2
He, B.3
Kostulas, N.4
Ozenci, V.5
Fredrikson, S.6
-
84
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MAC, Matthew J, Palace J, Newcombe J, Esiri MM, Fugger L. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 2008; 172: 146-55.
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.C.2
Matthew, J.3
Palace, J.4
Newcombe, J.5
Esiri, M.M.6
Fugger, L.7
-
85
-
-
0142058146
-
Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia
-
Li J, Gran B, Zhang G-X, Ventura ES, Siglienti I, Rostami A, et al. Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia. J Neurol Sci 2003; 215: 95-103.
-
(2003)
J Neurol Sci
, vol.215
, pp. 95-103
-
-
Li, J.1
Gran, B.2
Zhang, G.-X.3
Ventura, E.S.4
Siglienti, I.5
Rostami, A.6
-
86
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation in the brain
-
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation in the brain. Nature 2003; 421: 744-8.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
-
87
-
-
0019400456
-
Autoimmunity in insulin-dependent diabetes mellitus
-
Nerup J, Lernmark A. Autoimmunity in insulin-dependent diabetes mellitus. Am J Med 1981; 70: 135-41.
-
(1981)
Am J Med
, vol.70
, pp. 135-141
-
-
Nerup, J.1
Lernmark, A.2
-
88
-
-
0027361654
-
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
-
Itoh N, Hanafusa T, Miyazaki A, Miyagawa J-I, Yamagata K, Yamamoto K, et al. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 1993; 92: 2313-22.
-
(1993)
J Clin Invest
, vol.92
, pp. 2313-2322
-
-
Itoh, N.1
Hanafusa, T.2
Miyazaki, A.3
Miyagawa, J.-I.4
Yamagata, K.5
Yamamoto, K.6
-
89
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science 1986; 232: 1545-7.
-
(1986)
Science
, vol.232
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
90
-
-
0025011479
-
Interferon-gamma sensitizes rat pancreatic islet cells to lysis by cytokines and cytotoxic cells
-
Baquerizo HR, Alex. Interferon-gamma sensitizes rat pancreatic islet cells to lysis by cytokines and cytotoxic cells. J Autoimmun 1990; 3 Suppl 1: 123-30.
-
(1990)
J Autoimmun
, vol.3
, Issue.SUPPL. 1
, pp. 123-130
-
-
Baquerizo, H.R.1
Alex2
-
91
-
-
0027482258
-
Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus
-
Mandrup-Poulsen T, Zumsteq U, Reimers J, Pociot F, Morch L, Helqvist S, et al. Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus. Cytokine 1993; 5: 185-91.
-
(1993)
Cytokine
, vol.5
, pp. 185-191
-
-
Mandrup-Poulsen, T.1
Zumsteq, U.2
Reimers, J.3
Pociot, F.4
Morch, L.5
Helqvist, S.6
-
92
-
-
0025981388
-
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice
-
Campbell IL, Kay TWH, Oxbrow L, Harrison LC. Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. J Clin Invest 1991; 87: 739-42.
-
(1991)
J Clin Invest
, vol.87
, pp. 739-742
-
-
Campbell, I.L.1
Kay, T.W.H.2
Oxbrow, L.3
Harrison, L.C.4
-
93
-
-
0028882673
-
Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E
-
Hancock WW, Polanski M, Zhang J, Blogg N, Weiner HL. Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E. Am J Pathol 1995; 147: 1193-9.
-
(1995)
Am J Pathol
, vol.147
, pp. 1193-1199
-
-
Hancock, W.W.1
Polanski, M.2
Zhang, J.3
Blogg, N.4
Weiner, H.L.5
-
94
-
-
0029989197
-
Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: Identification of iNOS-expressing cells and relationships to cytokines expressed in the islets
-
Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC. Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: Identification of iNOS-expressing cells and relationships to cytokines expressed in the islets. Endocrinology 1996; 137: 2093-9.
-
(1996)
Endocrinology
, vol.137
, pp. 2093-2099
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
-
95
-
-
0031051747
-
Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus
-
von Herrath MG, Oldstone MBA. Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus. J Exp Med 1997; 185: 531-9.
-
(1997)
J Exp Med
, vol.185
, pp. 531-539
-
-
von Herrath, M.G.1
Oldstone, M.B.A.2
-
96
-
-
0031183099
-
Role of macrophages and macrophages-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes-resistant biobreeding rats
-
Chung Y-H, Jun H-S, Kang Y, Hirasawa K, Lee B-R, Van Rooijen N, et al. Role of macrophages and macrophages-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes-resistant biobreeding rats. J Immunol 1997; 159: 466-71.
-
(1997)
J Immunol
, vol.159
, pp. 466-471
-
-
Chung, Y.-H.1
Jun, H.-S.2
Kang, Y.3
Hirasawa, K.4
Lee, B.-R.5
Van Rooijen, N.6
-
97
-
-
0029764082
-
Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction
-
Suarez-Pinzon WL, Rajotte RV, Mosmann TR, Rabinovitch A. Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction. Diabetes 1996; 45: 1350-7.
-
(1996)
Diabetes
, vol.45
, pp. 1350-1357
-
-
Suarez-Pinzon, W.L.1
Rajotte, R.V.2
Mosmann, T.R.3
Rabinovitch, A.4
-
99
-
-
0028989087
-
IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice
-
Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF. IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J Immunol 1995; 154: 4874-82.
-
(1995)
J Immunol
, vol.154
, pp. 4874-4882
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
Power, R.F.5
-
100
-
-
0029948898
-
Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice
-
Hultgren B, Huang X, Dybdal N, Stewart T. Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice. Diabetes 1996; 45: 812-7.
-
(1996)
Diabetes
, vol.45
, pp. 812-817
-
-
Hultgren, B.1
Huang, X.2
Dybdal, N.3
Stewart, T.4
-
101
-
-
0028346888
-
Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice
-
Wogensen L, Lee M-S, Sarvetnick N. Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice. J Exp Med 1994; 179: 1379-84.
-
(1994)
J Exp Med
, vol.179
, pp. 1379-1384
-
-
Wogensen, L.1
Lee, M.-S.2
Sarvetnick, N.3
-
102
-
-
0037514387
-
IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12 induced IFN-gamma
-
Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L. IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12 induced IFN-gamma. J Immunol 2003; 170: 5491-501.
-
(2003)
J Immunol
, vol.170
, pp. 5491-5501
-
-
Trembleau, S.1
Penna, G.2
Gregori, S.3
Giarratana, N.4
Adorini, L.5
-
103
-
-
0031127982
-
Interleukin 1-beta, tumour necrosis factor-alpha and interleukin 1 receptor antagonist in newly diagnosed insulin-dependent diabetes mellitus: Comparison to long-standing diabetes and healthy individuals
-
Netea MG, Hancu N, Blok WL, Grigorescu-Sido P, Popa L, Popa V, et al. Interleukin 1-beta, tumour necrosis factor-alpha and interleukin 1 receptor antagonist in newly diagnosed insulin-dependent diabetes mellitus: Comparison to long-standing diabetes and healthy individuals. Cytokine 1997; 9: 284-7.
-
(1997)
Cytokine
, vol.9
, pp. 284-287
-
-
Netea, M.G.1
Hancu, N.2
Blok, W.L.3
Grigorescu-Sido, P.4
Popa, L.5
Popa, V.6
-
104
-
-
0032413626
-
Decreased secretion of Th2 cytokines precedes up-regulated and delayed secretion of Th1 cytokines in activated peripheral blood mononuclear cells from patients with insulin-dependent diabetes mellitus
-
Rapoport MJ, Vardi AM, Ramot Y, Winker R, Hindi A, Bistritzer T. Decreased secretion of Th2 cytokines precedes up-regulated and delayed secretion of Th1 cytokines in activated peripheral blood mononuclear cells from patients with insulin-dependent diabetes mellitus. J Autoimmun 1998; 11: 635-42.
-
(1998)
J Autoimmun
, vol.11
, pp. 635-642
-
-
Rapoport, M.J.1
Vardi, A.M.2
Ramot, Y.3
Winker, R.4
Hindi, A.5
Bistritzer, T.6
-
105
-
-
0035041401
-
Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects positive for diabetes-associated autoantibodies
-
Halminen M, Simell O, Knip M, Ilonen J. Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects positive for diabetes-associated autoantibodies. Scand J Immunol 2001; 53: 510-3.
-
(2001)
Scand J Immunol
, vol.53
, pp. 510-513
-
-
Halminen, M.1
Simell, O.2
Knip, M.3
Ilonen, J.4
-
106
-
-
0028326474
-
Evidence of CD4+ regulatory T cells in the non-obese diabetic male mouse
-
Sempé P, Rochard MFB, JF, Boitard C. Evidence of CD4+ regulatory T cells in the non-obese diabetic male mouse. Diabetologia 1994; 37: 337-43.
-
(1994)
Diabetologia
, vol.37
, pp. 337-343
-
-
Sempé, P.1
Rochard2
MFB, J.F.3
Boitard, C.4
-
107
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja A, Cost G, Marker J, Zhang C, Sun Z, Lin-Su K, et al. Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest 2002; 109: 131-40.
-
(2002)
J Clin Invest
, vol.109
, pp. 131-140
-
-
Kukreja, A.1
Cost, G.2
Marker, J.3
Zhang, C.4
Sun, Z.5
Lin-Su, K.6
-
109
-
-
0027103723
-
The development of manifest psoriatic lesions is linked with the invasion of CD8+ T cells and CD11c + macrophages into the epidermis
-
Paukkonen K, Naukkarinen A, Horsmanheimo M. The development of manifest psoriatic lesions is linked with the invasion of CD8+ T cells and CD11c + macrophages into the epidermis. Arch Dermatol Res 1992; 284: 375-9.
-
(1992)
Arch Dermatol Res
, vol.284
, pp. 375-379
-
-
Paukkonen, K.1
Naukkarinen, A.2
Horsmanheimo, M.3
-
110
-
-
0025873041
-
Genomic, phenotypic, and functional analyses of T cells in patients with psoriasis undergoing systemic cyclosporin A treatment
-
Takashima A, Morita A. Genomic, phenotypic, and functional analyses of T cells in patients with psoriasis undergoing systemic cyclosporin A treatment. J Invest Dermatol 1991; 96: 376-82.
-
(1991)
J Invest Dermatol
, vol.96
, pp. 376-382
-
-
Takashima, A.1
Morita, A.2
-
111
-
-
0026755558
-
Tacrolimus (FK 506) - a new therapeutic agent for severe recalcitrant psoriasis
-
Jegasothy BV, Ackerman CD, Todos S, Fung JJ, Abu-Elmagd KS, TE. Tacrolimus (FK 506) - a new therapeutic agent for severe recalcitrant psoriasis. Arch Dermatol 1992; 128: 781-5.
-
(1992)
Arch Dermatol
, vol.128
, pp. 781-785
-
-
Jegasothy, B.V.1
Ackerman, C.D.2
Todos, S.3
Fung, J.J.4
Abu-Elmagd, K.T.5
-
112
-
-
0032519956
-
IL-10 is a key cytokine in psoriasis
-
Asadullah K, Sterry W, Sephanek K, Jasulaitis D, Leupold M, Audring H, et al. IL-10 is a key cytokine in psoriasis. J Clin Invest 1998; 101: 783-94.
-
(1998)
J Clin Invest
, vol.101
, pp. 783-794
-
-
Asadullah, K.1
Sterry, W.2
Sephanek, K.3
Jasulaitis, D.4
Leupold, M.5
Audring, H.6
-
113
-
-
0021086933
-
Detection of interferon in the sera of patients with psoriasis, and its enhancement by PUVA treatment
-
Diezel W, Waschke S, Sönnichsen N. Detection of interferon in the sera of patients with psoriasis, and its enhancement by PUVA treatment. Br J Dermatol 1983; 109: 549-52.
-
(1983)
Br J Dermatol
, vol.109
, pp. 549-552
-
-
Diezel, W.1
Waschke, S.2
Sönnichsen, N.3
-
114
-
-
0020677930
-
Interferon in suction blister fluid from psoriatic lesions
-
Bjerke J, Livden J, Degré M, Matre R. Interferon in suction blister fluid from psoriatic lesions. Br J Dermatol 1982; 108: 295-9.
-
(1982)
Br J Dermatol
, vol.108
, pp. 295-299
-
-
Bjerke, J.1
Livden, J.2
Degré, M.3
Matre, R.4
-
115
-
-
0032729645
-
The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (Cytotoxic T Lymphocyte) and Th1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
-
Austin LM, Ozawa M, Kikuchi T, Walters IB, Krueger JG. The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (Cytotoxic T Lymphocyte) and Th1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 1999; 113: 752-9.
-
(1999)
J Invest Dermatol
, vol.113
, pp. 752-759
-
-
Austin, L.M.1
Ozawa, M.2
Kikuchi, T.3
Walters, I.B.4
Krueger, J.G.5
-
116
-
-
0024573776
-
The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes
-
Larsen CG, Anderson AO, Appella E, Oppenheim JJ, Matsushima K. The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes. Science 1989; 243: 1464-6.
-
(1989)
Science
, vol.243
, pp. 1464-1466
-
-
Larsen, C.G.1
Anderson, A.O.2
Appella, E.3
Oppenheim, J.J.4
Matsushima, K.5
-
117
-
-
0025189816
-
Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors
-
Barker JNWN, Sarma V, Mitra RS, Dixit VM, Nickoloff BJ. Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors. J Clin Invest 1990; 85: 605-8.
-
(1990)
J Clin Invest
, vol.85
, pp. 605-608
-
-
Barker, J.N.W.N.1
Sarma, V.2
Mitra, R.S.3
Dixit, V.M.4
Nickoloff, B.J.5
-
118
-
-
0026087048
-
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis
-
Nickoloff BJ, Karabin GD, Barker JNWN, Griffiths CEM, Sarma V, Mitra RS, et al. Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol 1991; 138: 129-41.
-
(1991)
Am J Pathol
, vol.138
, pp. 129-141
-
-
Nickoloff, B.J.1
Karabin, G.D.2
Barker, J.N.W.N.3
Griffiths, C.E.M.4
Sarma, V.5
Mitra, R.S.6
-
120
-
-
0029012458
-
Increased spontaneous production of IL-8 in peripheral blood monocytes from the psoriatic patient: Relation to focal infection and response to treatments
-
Teranishi Y, Mizutani H, Murata M, Shimizu M, Matsushima K. Increased spontaneous production of IL-8 in peripheral blood monocytes from the psoriatic patient: Relation to focal infection and response to treatments. J Dermatol Sci 1995; 10: 8-15.
-
(1995)
J Dermatol Sci
, vol.10
, pp. 8-15
-
-
Teranishi, Y.1
Mizutani, H.2
Murata, M.3
Shimizu, M.4
Matsushima, K.5
-
121
-
-
0032127709
-
Peripheral blood monocytes in psoriatic patients overproduce cytokines
-
Okubo Y, Koga M. Peripheral blood monocytes in psoriatic patients overproduce cytokines. J Dermatol Sci 1998; 17: 223-32.
-
(1998)
J Dermatol Sci
, vol.17
, pp. 223-232
-
-
Okubo, Y.1
Koga, M.2
-
122
-
-
0242693481
-
Simultaneous measurement of multiple Th1 and Th2 serum cytokines in psoriasis and correlation with disease severity
-
Jacob SE, Nassiri M, Kerdel FA, Vincek V. Simultaneous measurement of multiple Th1 and Th2 serum cytokines in psoriasis and correlation with disease severity. Mediators Inflamm 2003; 12: 309-13.
-
(2003)
Mediators Inflamm
, vol.12
, pp. 309-313
-
-
Jacob, S.E.1
Nassiri, M.2
Kerdel, F.A.3
Vincek, V.4
-
123
-
-
0028108176
-
T lymphocytes derived from skin lesions of patients with psoriasis vulgaris express a novel cytokine pattern that is distinct from that of T helper type 1 and T helper type 2 cells
-
Vollmer S, Menssen AT, P, Schendel D, Prinz JC. T lymphocytes derived from skin lesions of patients with psoriasis vulgaris express a novel cytokine pattern that is distinct from that of T helper type 1 and T helper type 2 cells. Eur J Immunol 1994; 24: 2377-82.
-
(1994)
Eur J Immunol
, vol.24
, pp. 2377-2382
-
-
Vollmer, S.1
Menssen2
AT, P.3
Schendel, D.4
Prinz, J.C.5
-
124
-
-
0028674179
-
IL-10 levels are decreased in psoriatic lesional skin as compared to the psoriatic lesion-free and normal skin suction blister fluids
-
Mussi A, Bonifati C, Carducci M, Viola M, Tomaselli R, Sacerdoti G, et al. IL-10 levels are decreased in psoriatic lesional skin as compared to the psoriatic lesion-free and normal skin suction blister fluids. J Biol Regul Homeost Agents 1994; 8: 117-20.
-
(1994)
J Biol Regul Homeost Agents
, vol.8
, pp. 117-120
-
-
Mussi, A.1
Bonifati, C.2
Carducci, M.3
Viola, M.4
Tomaselli, R.5
Sacerdoti, G.6
-
125
-
-
0001088219
-
Purification and characterization of a newly identified growth factor specific for epithelial cells
-
Rubin JS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA. Purification and characterization of a newly identified growth factor specific for epithelial cells. PNAS 1989; 86: 802-6.
-
(1989)
PNAS
, vol.86
, pp. 802-806
-
-
Rubin, J.S.1
Osada, H.2
Finch, P.W.3
Taylor, W.G.4
Rudikoff, S.5
Aaronson, S.A.6
-
126
-
-
0030687496
-
Altered expression of keratinocyte growth factor and its receptor in psoriasis
-
Finch PW, Murphy F, Cardinale IR, Krueger JG. Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol 1997; 151: 1619-28.
-
(1997)
Am J Pathol
, vol.151
, pp. 1619-1628
-
-
Finch, P.W.1
Murphy, F.2
Cardinale, I.R.3
Krueger, J.G.4
-
127
-
-
0021224661
-
Lymphocyte chemotactic activity of human interleukin 1
-
Miossec P, Yu C-L, Ziff M. Lymphocyte chemotactic activity of human interleukin 1. J Immunol 1984; 133: 2007-11.
-
(1984)
J Immunol
, vol.133
, pp. 2007-2011
-
-
Miossec, P.1
Yu, C.-L.2
Ziff, M.3
-
128
-
-
0022518045
-
In vivo inflammatory activity of epidermal cell-derived thymocyte activating factor and recombinant interleukin 1 in the mouse
-
Granstein RD, Margolis R, Mizel SB, Sauder DN. In vivo inflammatory activity of epidermal cell-derived thymocyte activating factor and recombinant interleukin 1 in the mouse. J Clin Invest 1986; 77: 1020-7.
-
(1986)
J Clin Invest
, vol.77
, pp. 1020-1027
-
-
Granstein, R.D.1
Margolis, R.2
Mizel, S.B.3
Sauder, D.N.4
-
129
-
-
0023099754
-
Expression of mRNA homologous to interleukin 1 in human epidermal cells
-
Bell TV, Harley CB, Stetsko D, Sauder DN. Expression of mRNA homologous to interleukin 1 in human epidermal cells. J Invest Dermatol 1987; 88: 375-9.
-
(1987)
J Invest Dermatol
, vol.88
, pp. 375-379
-
-
Bell, T.V.1
Harley, C.B.2
Stetsko, D.3
Sauder, D.N.4
-
130
-
-
0024359054
-
In situ localization of interleukin-1 in normal and psoriatic skin
-
Romero LI, Ikejima T, Pincus SH. In situ localization of interleukin-1 in normal and psoriatic skin. J Invest Dermatol 1989; 93: 518-22.
-
(1989)
J Invest Dermatol
, vol.93
, pp. 518-522
-
-
Romero, L.I.1
Ikejima, T.2
Pincus, S.H.3
-
131
-
-
0025780270
-
Interleukin 1 alpha, tumor necrosis factor alpha, and interferon gamma in psoriasis
-
Gomi T, Shiohara T, Munakata T, Imanishi K, Nagashima M. Interleukin 1 alpha, tumor necrosis factor alpha, and interferon gamma in psoriasis. Arch Dermatol 1991; 127: 827-30.
-
(1991)
Arch Dermatol
, vol.127
, pp. 827-830
-
-
Gomi, T.1
Shiohara, T.2
Munakata, T.3
Imanishi, K.4
Nagashima, M.5
-
132
-
-
0343019918
-
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes
-
Grossman RM, Krueger JG, Yourish D, Granelli-Piperno A, Murphy DP, May LT, et al. Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. PNAS 1989; 86: 6367-71.
-
(1989)
PNAS
, vol.86
, pp. 6367-6371
-
-
Grossman, R.M.1
Krueger, J.G.2
Yourish, D.3
Granelli-Piperno, A.4
Murphy, D.P.5
May, L.T.6
-
133
-
-
0028233818
-
Elevated tumour necrosis factor alpha (TNF-alpha) biological activity in psoriatic skin lesions
-
Ettehadi P, Greaves MW, Wallach D, Aderka D, Camp RDR. Elevated tumour necrosis factor alpha (TNF-alpha) biological activity in psoriatic skin lesions. Clin Exp Immunol 1994; 96: 146-51.
-
(1994)
Clin Exp Immunol
, vol.96
, pp. 146-151
-
-
Ettehadi, P.1
Greaves, M.W.2
Wallach, D.3
Aderka, D.4
Camp, R.D.R.5
-
134
-
-
0031469174
-
Serum TNF-alpha levels correlate with disease severity and are reduced by effective therapy in plaque-type psoriasis
-
Mussi A, Bonifati C, Carducci M, D'Agosto G, Pimpinelli F, D'Urso D, et al. Serum TNF-alpha levels correlate with disease severity and are reduced by effective therapy in plaque-type psoriasis. J Biol Regul Homeost Agents 1997; 11: 115-8.
-
(1997)
J Biol Regul Homeost Agents
, vol.11
, pp. 115-118
-
-
Mussi, A.1
Bonifati, C.2
Carducci, M.3
D'Agosto, G.4
Pimpinelli, F.5
D'Urso, D.6
-
135
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptative immunity
-
Trinchieri G. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptative immunity. Annu Rev Immunol 1995; 13: 251-76.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
136
-
-
0032448380
-
Expression of interleukin-12 is increased in psoriatic skin
-
Yawalkar N, Karlen S, Hunger R, Brand CU, Braathen LR. Expression of interleukin-12 is increased in psoriatic skin. J Invest Dermatol 1998; 111: 1053-7.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 1053-1057
-
-
Yawalkar, N.1
Karlen, S.2
Hunger, R.3
Brand, C.U.4
Braathen, L.R.5
-
137
-
-
0347285359
-
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
-
Lee E, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F, et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004; 199: 125-30.
-
(2004)
J Exp Med
, vol.199
, pp. 125-130
-
-
Lee, E.1
Trepicchio, W.L.2
Oestreicher, J.L.3
Pittman, D.4
Wang, F.5
Chamian, F.6
-
138
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal S, Ghilardi N, Xie M-H, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003; 278: 1910-4.
-
(2003)
J Biol Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.-H.3
de Sauvage, F.J.4
Gurney, A.L.5
-
139
-
-
0037362498
-
The role of interleukin-17 in inducible nitric oxide synthase-mediated nitric oxide production in endothelial cells
-
Miljkovic D, Cvetkovic I, Vickovic O, Stosic-Grujicic S, Mostarica Stojkovic M, Trajkovic V. The role of interleukin-17 in inducible nitric oxide synthase-mediated nitric oxide production in endothelial cells. Cell Mol Life Sci 2003; 60: 518-25.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 518-525
-
-
Miljkovic, D.1
Cvetkovic, I.2
Vickovic, O.3
Stosic-Grujicic, S.4
Mostarica Stojkovic, M.5
Trajkovic, V.6
-
140
-
-
0033404492
-
Interleukin-11 therapy selectively downregulates type 1 cytokine proinflammatory pathways in psoriasis lesions
-
Trepicchio WL, Ozawa M, Walters IB, Kikuchi T, Gilleaudeau P, Bliss JL, et al. Interleukin-11 therapy selectively downregulates type 1 cytokine proinflammatory pathways in psoriasis lesions. J Clin Invest 1999; 104: 1527-37.
-
(1999)
J Clin Invest
, vol.104
, pp. 1527-1537
-
-
Trepicchio, W.L.1
Ozawa, M.2
Walters, I.B.3
Kikuchi, T.4
Gilleaudeau, P.5
Bliss, J.L.6
-
141
-
-
0036604062
-
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells
-
Belladonna ML, Renauld J-C, Bianchi R, Vacca C, Fallarino F, Orabona C, et al. IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. J Immunol 2002; 168: 5448-54.
-
(2002)
J Immunol
, vol.168
, pp. 5448-5454
-
-
Belladonna, M.L.1
Renauld, J.-C.2
Bianchi, R.3
Vacca, C.4
Fallarino, F.5
Orabona, C.6
-
142
-
-
0038189842
-
IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity
-
Kopp T, Lenz P, Bello-Fernandez C, Kastelein RA, Kupper TS, Stingl G. IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity. J Immunol 2003; 170: 5438-44.
-
(2003)
J Immunol
, vol.170
, pp. 5438-5444
-
-
Kopp, T.1
Lenz, P.2
Bello-Fernandez, C.3
Kastelein, R.A.4
Kupper, T.S.5
Stingl, G.6
-
143
-
-
33846906224
-
Interleukin-22, a T(h)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Ouyang W. Interleukin-22, a T(h)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007; 445: 648-51.
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
Kasman, I.4
Eastham-Anderson, J.5
Ouyang, W.6
-
144
-
-
0346096722
-
Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
-
Villadsen LS, Schuurman J, Beurskens F, Dam TN, Dagnaes-Hansen F, Skov L, et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest 2003; 112: 1571-80.
-
(2003)
J Clin Invest
, vol.112
, pp. 1571-1580
-
-
Villadsen, L.S.1
Schuurman, J.2
Beurskens, F.3
Dam, T.N.4
Dagnaes-Hansen, F.5
Skov, L.6
-
145
-
-
0034881918
-
New insights into the role of cytokines in asthma
-
Renauld J-C. New insights into the role of cytokines in asthma. J Clin Pathol 2001; 54: 577-89.
-
(2001)
J Clin Pathol
, vol.54
, pp. 577-589
-
-
Renauld, J.-C.1
-
146
-
-
0033604544
-
The alliance of genes and environment in asthma and allergy
-
Cookson W. The alliance of genes and environment in asthma and allergy. Nature 1999; 402: B5-11.
-
(1999)
Nature
, vol.402
-
-
Cookson, W.1
-
147
-
-
0031226757
-
Eosinophil-associated TGF-beta 1 mRNA expression and airways fibrosis in bronchial asthma
-
Minshall EM, Leung DYM, Martin RJ, Song YL, Cameron L, Ernst P, et al. Eosinophil-associated TGF-beta 1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 1997; 17: 326-33.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 326-333
-
-
Minshall, E.M.1
Leung, D.Y.M.2
Martin, R.J.3
Song, Y.L.4
Cameron, L.5
Ernst, P.6
-
148
-
-
0030236307
-
-
Ohno I, Nitta Y, Yamauchi K, Hoshi HH, M, Woodley K, O'Byrne P, et al. Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation. Am J Respir Cell Mol Biol 1996; 15: 404-9.
-
Ohno I, Nitta Y, Yamauchi K, Hoshi HH, M, Woodley K, O'Byrne P, et al. Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation. Am J Respir Cell Mol Biol 1996; 15: 404-9.
-
-
-
-
149
-
-
0025611180
-
Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma
-
Azzawi M, Bradley B, Jeffery PK, Frew AJ, Wardlaw AJ, Knowles G, et al. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990; 142: 1407-13.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 1407-1413
-
-
Azzawi, M.1
Bradley, B.2
Jeffery, P.K.3
Frew, A.J.4
Wardlaw, A.J.5
Knowles, G.6
-
150
-
-
0026871242
-
T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis
-
Azzawi M, Johnston PW, Majumdar S, Kay AB, Jeffery PK. T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis. Am Rev Respir Dis 1992; 145: 1477-82.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1477-1482
-
-
Azzawi, M.1
Johnston, P.W.2
Majumdar, S.3
Kay, A.B.4
Jeffery, P.K.5
-
151
-
-
0026610142
-
Predominant Th2-like bronchoalveolar Tlymphocyte population in atopic asthma
-
Robinson DS, Hamid QA, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant Th2-like bronchoalveolar Tlymphocyte population in atopic asthma. N Engl J Med 1992; 326: 298-304.
-
(1992)
N Engl J Med
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.A.2
Ying, S.3
Tsicopoulos, A.4
Barkans, J.5
Bentley, A.M.6
-
152
-
-
0026876653
-
Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways
-
Gratziou C, Carroll M, Walls A, Howarth P, Holgate ST. Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways. Am Rev Respir Dis 1992; 145: 1259-64.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1259-1264
-
-
Gratziou, C.1
Carroll, M.2
Walls, A.3
Howarth, P.4
Holgate, S.T.5
-
153
-
-
0025037094
-
Eosinophilic inflammation in asthma
-
Bousquet J, Chanez P, Lacoste J, Barneon G, Ghavanian N, Enander I, et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323: 1033-9.
-
(1990)
N Engl J Med
, vol.323
, pp. 1033-1039
-
-
Bousquet, J.1
Chanez, P.2
Lacoste, J.3
Barneon, G.4
Ghavanian, N.5
Enander, I.6
-
154
-
-
0025008579
-
The eosinophil and bronchial asthma: Current understanding
-
Gleich G. The eosinophil and bronchial asthma: Current understanding. J Allergy Clin Immunol 1990; 85: 422-36.
-
(1990)
J Allergy Clin Immunol
, vol.85
, pp. 422-436
-
-
Gleich, G.1
-
155
-
-
0025324736
-
Mucosal inflammation in asthma
-
Djukanovic R, Roche W, Wilson J, Beasley C, Twentyman O, Howarth R, et al. Mucosal inflammation in asthma. Am Rev Respir Dis 1990; 142: 434-57.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 434-457
-
-
Djukanovic, R.1
Roche, W.2
Wilson, J.3
Beasley, C.4
Twentyman, O.5
Howarth, R.6
-
156
-
-
0025905118
-
Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production
-
Parronchi P, Macchia D, Piccinni M-P, Biswas P, Simonelli C, Maggi E, et al. Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. PNAS 1991; 88: 4538-42.
-
(1991)
PNAS
, vol.88
, pp. 4538-4542
-
-
Parronchi, P.1
Macchia, D.2
Piccinni, M.-P.3
Biswas, P.4
Simonelli, C.5
Maggi, E.6
-
157
-
-
0026333085
-
Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease activity
-
Walker C, Kaegi MK, Braun P, Blaser K. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease activity. J Allergy Clin Immunol 1991; 88: 935-42.
-
(1991)
J Allergy Clin Immunol
, vol.88
, pp. 935-942
-
-
Walker, C.1
Kaegi, M.K.2
Braun, P.3
Blaser, K.4
-
158
-
-
0026666718
-
Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
-
Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JCJ. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992; 146: 109-15.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 109-115
-
-
Walker, C.1
Bode, E.2
Boer, L.3
Hansel, T.T.4
Blaser, K.5
Virchow, J.C.J.6
-
159
-
-
0027197709
-
Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
-
Del Prete G, De Carli M, D'Elios MM, Mastrelli P, Ricci M, Fabbri L, et al. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur J Immunol 1993; 23: 1445-9.
-
(1993)
Eur J Immunol
, vol.23
, pp. 1445-1449
-
-
Del Prete, G.1
De Carli, M.2
D'Elios, M.M.3
Mastrelli, P.4
Ricci, M.5
Fabbri, L.6
-
160
-
-
0024564031
-
Mast cell lines produce lymphokines in response to crosslinkage of Fc epsilon RI or to calcium ionophores
-
Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordan RP, Paul WE. Mast cell lines produce lymphokines in response to crosslinkage of Fc epsilon RI or to calcium ionophores. Nature 1989; 339: 64-7.
-
(1989)
Nature
, vol.339
, pp. 64-67
-
-
Plaut, M.1
Pierce, J.H.2
Watson, C.J.3
Hanley-Hyde, J.4
Nordan, R.P.5
Paul, W.E.6
-
161
-
-
0028432821
-
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines
-
Bradding P, Roberts J, Britten K, Montefort S, Djukanovic R, Mueler R, et al. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994; 10: 471-80
-
(1994)
Am J Respir Cell Mol Biol
, vol.10
, pp. 471-480
-
-
Bradding, P.1
Roberts, J.2
Britten, K.3
Montefort, S.4
Djukanovic, R.5
Mueler, R.6
-
162
-
-
0026482042
-
Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics
-
Broide DH, Paine MM, Firestein GS. Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J Clin Invest 1992; 90: 1414-24
-
(1992)
J Clin Invest
, vol.90
, pp. 1414-1424
-
-
Broide, D.H.1
Paine, M.M.2
Firestein, G.S.3
-
163
-
-
0030068235
-
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
-
Corry D, Folkesson H, Warnock M, Erle D, Matthay M, Wiener-Kronish J, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996; 183: 109-17.
-
(1996)
J Exp Med
, vol.183
, pp. 109-117
-
-
Corry, D.1
Folkesson, H.2
Warnock, M.3
Erle, D.4
Matthay, M.5
Wiener-Kronish, J.6
-
164
-
-
0023204258
-
Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells
-
Hudak SA, Gollnick SO, Conrad DH, Kehry MR. Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells. PNAS 1987; 84: 4606-10.
-
(1987)
PNAS
, vol.84
, pp. 4606-4610
-
-
Hudak, S.A.1
Gollnick, S.O.2
Conrad, D.H.3
Kehry, M.R.4
-
165
-
-
0023785192
-
Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures
-
Lebman DA, Coffman RL. Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures. J Exp Med 1988; 168: 853-62
-
(1988)
J Exp Med
, vol.168
, pp. 853-862
-
-
Lebman, D.A.1
Coffman, R.L.2
-
166
-
-
0028201726
-
Acquisition of lymphokine-producing phenotype by CD4+ T cells
-
Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994; 12: 635-73.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 635-673
-
-
Seder, R.A.1
Paul, W.E.2
-
167
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf M, Le Gros G, Bachmann MF, Lamers MC, Bluethmann H, Köhler G. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993; 362: 245-8.
-
(1993)
Nature
, vol.362
, pp. 245-248
-
-
Kopf, M.1
Le Gros, G.2
Bachmann, M.F.3
Lamers, M.C.4
Bluethmann, H.5
Köhler, G.6
-
168
-
-
0033562979
-
Th2-induced airway mucus production is dependent on IL-4R-alpha, but not on eosinophils
-
Cohn L, Homer RJ, MacLeod H, Mohrs M, Brombacher F, Bottomly K. Th2-induced airway mucus production is dependent on IL-4R-alpha, but not on eosinophils. J Immunol 1999; 162: 6178- 83.
-
J Immunol 1999; 162: 6178- 83
-
-
Cohn, L.1
Homer, R.J.2
MacLeod, H.3
Mohrs, M.4
Brombacher, F.5
Bottomly, K.6
-
169
-
-
16044371529
-
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
-
Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad BD, B, Tarallo A, et al. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity. PNAS 1996; 93: 7821-5.
-
(1996)
PNAS
, vol.93
, pp. 7821-7825
-
-
Rankin, J.A.1
Picarella, D.E.2
Geba, G.P.3
Temann, U.A.4
Prasad5
BD, B.6
Tarallo, A.7
-
170
-
-
0023879839
-
Recombinant human interleukin 5 is a selective activator of human eosinophil function
-
Lopez AF, Sanderson CJ, Gamble JR, Campbell HD, Young IG, Vadas MA. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J Exp Med 1988; 167: 219-24.
-
(1988)
J Exp Med
, vol.167
, pp. 219-224
-
-
Lopez, A.F.1
Sanderson, C.J.2
Gamble, J.R.3
Campbell, H.D.4
Young, I.G.5
Vadas, M.A.6
-
171
-
-
0034945391
-
Eosinophils and respiratory disease
-
Venge P. Eosinophils and respiratory disease. Respir Med 2001; 95: 168-9.
-
(2001)
Respir Med
, vol.95
, pp. 168-169
-
-
Venge, P.1
-
172
-
-
0027274890
-
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
-
Zurawski SM, Vega FJ, Huyghe B, Zurawski G. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J 1993; 12: 2663-70.
-
(1993)
EMBO J
, vol.12
, pp. 2663-2670
-
-
Zurawski, S.M.1
Vega, F.J.2
Huyghe, B.3
Zurawski, G.4
-
173
-
-
38649137731
-
Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system
-
LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, et al. Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell 2008; 132: 179-81.
-
(2008)
Cell
, vol.132
, pp. 179-181
-
-
LaPorte, S.L.1
Juo, Z.S.2
Vaclavikova, J.3
Colf, L.A.4
Qi, X.5
Heller, N.M.6
-
174
-
-
45549122275
-
IL-13 as a therapeutic target for respiratory disease
-
Kasaian MT, Miller DK. IL-13 as a therapeutic target for respiratory disease. Biochem Pharmacol 2008; 76: 147-55.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 147-155
-
-
Kasaian, M.T.1
Miller, D.K.2
-
175
-
-
0029038120
-
IL-13 expression at the sites of allergen challenge in patients with asthma
-
Huang S-K, Xiao H-Q, Kleine-Tebbe J, Paciotti G, Marsh DG, Lichtenstein LM, et al. IL-13 expression at the sites of allergen challenge in patients with asthma. J Immunol 1995; 155: 2688-94.
-
(1995)
J Immunol
, vol.155
, pp. 2688-2694
-
-
Huang, S.-K.1
Xiao, H.-Q.2
Kleine-Tebbe, J.3
Paciotti, G.4
Marsh, D.G.5
Lichtenstein, L.M.6
-
176
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grünig G, Warnock ML, Wakil AE, Venkayya R, Brombacher F, Rennick DM, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282: 2261-3.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grünig, G.1
Warnock, M.L.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
-
177
-
-
0032968706
-
Immunologic basis of antigen-induced airway hyperresponsiveness
-
Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999; 17: 255-81.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 255-281
-
-
Wills-Karp, M.1
-
178
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103: 779-88.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
-
179
-
-
0033577811
-
Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
-
McKenzie GJ, Fallon PG, Emson CL, Grencis RK, McKenzie ANJ. Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J Exp Med 1999; 189: 1565-72.
-
(1999)
J Exp Med
, vol.189
, pp. 1565-1572
-
-
McKenzie, G.J.1
Fallon, P.G.2
Emson, C.L.3
Grencis, R.K.4
McKenzie, A.N.J.5
-
180
-
-
9844247994
-
Genetic control of serum IgE levels and asthma: Linkage and linkage disequilibrium studies in an isolated population
-
Laitinen T, Kauppi P, Ignatius J, Ruotsalainen T, Daly MJ, Kääriäinen H, et al. Genetic control of serum IgE levels and asthma: Linkage and linkage disequilibrium studies in an isolated population. Hum Mol Genet 1997; 6: 2069-76.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2069-2076
-
-
Laitinen, T.1
Kauppi, P.2
Ignatius, J.3
Ruotsalainen, T.4
Daly, M.J.5
Kääriäinen, H.6
-
181
-
-
0031952088
-
-
Demoulin JR, JC. Interleukin 9 and its receptor: An overview of structure and function. Int Rev Immunol 1998; 16: 345-64.
-
Demoulin JR, JC. Interleukin 9 and its receptor: An overview of structure and function. Int Rev Immunol 1998; 16: 345-64.
-
-
-
-
182
-
-
0034517511
-
IL-9 expression by human eosinophils: Regulation by IL-1beta and TNF-alpha
-
Gounni AS, Nutku E, Koussih L, Aris F, Louahed J, Levitt RC, et al. IL-9 expression by human eosinophils: Regulation by IL-1beta and TNF-alpha. J Allergy Clin Immunol 2000; 106: 460-6.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 460-466
-
-
Gounni, A.S.1
Nutku, E.2
Koussih, L.3
Aris, F.4
Louahed, J.5
Levitt, R.C.6
-
183
-
-
0028937777
-
T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma
-
Virchow JCJ, Walker C, Hafner D, Kortsik C, Werner P, Matthys H, et al. T cells and cytokines in bronchoalveolar lavage fluid after segmental allergen provocation in atopic asthma. Am J Respir Crit Care Med 1995; 151: 960-8.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 960-968
-
-
Virchow, J.C.J.1
Walker, C.2
Hafner, D.3
Kortsik, C.4
Werner, P.5
Matthys, H.6
-
184
-
-
4444262198
-
IL-9 and its receptor in allergic and nonallergic lung disease: Increased expression in asthma
-
Shimbara A, Christodoulopoulos P, Gounni AS, Olivenstein R, Nakamura Y, Levitt RC, et al. IL-9 and its receptor in allergic and nonallergic lung disease: Increased expression in asthma. J Allergy Clin Immunol 2000; 104: 108-15.
-
(2000)
J Allergy Clin Immunol
, vol.104
, pp. 108-115
-
-
Shimbara, A.1
Christodoulopoulos, P.2
Gounni, A.S.3
Olivenstein, R.4
Nakamura, Y.5
Levitt, R.C.6
-
185
-
-
28244479315
-
Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma
-
Howarth P, Babu K, Arshad H, Lau L, Buckley M, McConnel W, et al. Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. Thorax 2005; 60: 1012-8
-
(2005)
Thorax
, vol.60
, pp. 1012-1018
-
-
Howarth, P.1
Babu, K.2
Arshad, H.3
Lau, L.4
Buckley, M.5
McConnel, W.6
-
186
-
-
0023039225
-
A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
-
Senger DR, Perruzzi CA, Feder J, Dvorak HF. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 1986; 46: 5629-32.
-
(1986)
Cancer Res
, vol.46
, pp. 5629-5632
-
-
Senger, D.R.1
Perruzzi, C.A.2
Feder, J.3
Dvorak, H.F.4
-
187
-
-
0025933145
-
The vascular endothelial growth factor family of polypeptides
-
Ferrara N, Houck K, Jakeman L, Winer J, Leung D. The vascular endothelial growth factor family of polypeptides. J Cell Biochem 1991; 47: 211-8.
-
(1991)
J Cell Biochem
, vol.47
, pp. 211-218
-
-
Ferrara, N.1
Houck, K.2
Jakeman, L.3
Winer, J.4
Leung, D.5
-
188
-
-
0026505773
-
Molecular and biological properties of the vascular endothelial growth factor family of proteins
-
Ferrara N, Houck K, Jakeman L, Leung D. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 1992; 13: 18-32.
-
(1992)
Endocr Rev
, vol.13
, pp. 18-32
-
-
Ferrara, N.1
Houck, K.2
Jakeman, L.3
Leung, D.4
-
189
-
-
0037280306
-
The role of VEGF in normal and neoplastic hematopoiesis
-
Gerber H-P, Ferrara N. The role of VEGF in normal and neoplastic hematopoiesis. J Mol Med 2003; 81: 20-31.
-
(2003)
J Mol Med
, vol.81
, pp. 20-31
-
-
Gerber, H.-P.1
Ferrara, N.2
-
190
-
-
84907112391
-
Therapeutic effect of endogenous tumor necrosis factor on ascites Meth A sarcoma
-
Watanabe N, Niitsu Y, Sone H, Neda H, Urushizaki I, Yamamoto A, et al. Therapeutic effect of endogenous tumor necrosis factor on ascites Meth A sarcoma. Journal Immunopharmacol 1986; 8: 271-83.
-
(1986)
Journal Immunopharmacol
, vol.8
, pp. 271-283
-
-
Watanabe, N.1
Niitsu, Y.2
Sone, H.3
Neda, H.4
Urushizaki, I.5
Yamamoto, A.6
-
191
-
-
0022641789
-
Recombinant human tumor necrosis factor - II. Antitumor effect on murine and human tumors transplanted in mice
-
Sohmura Y, Nakata K, Yoshida H, Kashimoto S, Matsui Y, Furuichi H. Recombinant human tumor necrosis factor - II. Antitumor effect on murine and human tumors transplanted in mice. Int J Immunopharmacol 1986; 8: 357-68.
-
(1986)
Int J Immunopharmacol
, vol.8
, pp. 357-368
-
-
Sohmura, Y.1
Nakata, K.2
Yoshida, H.3
Kashimoto, S.4
Matsui, Y.5
Furuichi, H.6
-
192
-
-
0023178374
-
Phase I study of recombinant tumor necrosis factor in cancer patients
-
Blick M, Sherwin SA, Rosenblum M, Gutterman J. Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res 1987; 47: 2986-9.
-
(1987)
Cancer Res
, vol.47
, pp. 2986-2989
-
-
Blick, M.1
Sherwin, S.A.2
Rosenblum, M.3
Gutterman, J.4
-
193
-
-
0023684531
-
A phase I trial of intravenously-administered recombinant necrosis factor-alpha in cancer patients
-
Feinberg B, Kurzrock R, Talpaz M, Blick M, Saks S, Gutterman J. A phase I trial of intravenously-administered recombinant necrosis factor-alpha in cancer patients. J Clin Oncol 1988; 6: 1328-34.
-
(1988)
J Clin Oncol
, vol.6
, pp. 1328-1334
-
-
Feinberg, B.1
Kurzrock, R.2
Talpaz, M.3
Blick, M.4
Saks, S.5
Gutterman, J.6
-
194
-
-
0024316912
-
Paradoxical effects of tumour necrosis factor in experimental ovarian cancer
-
Malik ST, Griffin DB, Fiers W, Balkwill FR. Paradoxical effects of tumour necrosis factor in experimental ovarian cancer. Int J Cancer 1989; 44: 918-25.
-
(1989)
Int J Cancer
, vol.44
, pp. 918-925
-
-
Malik, S.T.1
Griffin, D.B.2
Fiers, W.3
Balkwill, F.R.4
-
195
-
-
44949269111
-
Cells secreting tumour necrosis factor show enhanced metastasis in nude mice
-
Malik ST, Naylor MS, East N, Oliff A, Balkwill FR. Cells secreting tumour necrosis factor show enhanced metastasis in nude mice. Eur J Cancer 1990; 26: 1031-4.
-
(1990)
Eur J Cancer
, vol.26
, pp. 1031-1034
-
-
Malik, S.T.1
Naylor, M.S.2
East, N.3
Oliff, A.4
Balkwill, F.R.5
-
196
-
-
0025687961
-
In situ detection of tumour necrosis factor in human ovarian cancer specimens
-
Naylor MS, Malik ST, Stamp GW, Jobling T, Balkwill FR. In situ detection of tumour necrosis factor in human ovarian cancer specimens. Eur J Cancer 1990; 26: 1027-30.
-
(1990)
Eur J Cancer
, vol.26
, pp. 1027-1030
-
-
Naylor, M.S.1
Malik, S.T.2
Stamp, G.W.3
Jobling, T.4
Balkwill, F.R.5
-
197
-
-
0028799391
-
Enhanced tumor cell expression of tumor necrosis factor receptors in head and neck squamous cell carcinoma
-
von Biberstein S, Spiro J, Lindquist R, Kreutzer D. Enhanced tumor cell expression of tumor necrosis factor receptors in head and neck squamous cell carcinoma. Am J Surg 1995; 170: 416-22.
-
(1995)
Am J Surg
, vol.170
, pp. 416-422
-
-
von Biberstein, S.1
Spiro, J.2
Lindquist, R.3
Kreutzer, D.4
-
198
-
-
0026814183
-
Tumour necrosis factor: Roles in cancer pathophysiology
-
Malik ST. Tumour necrosis factor: Roles in cancer pathophysiology. Semin Cancer Biol 1992; 3: 27-33.
-
(1992)
Semin Cancer Biol
, vol.3
, pp. 27-33
-
-
Malik, S.T.1
-
199
-
-
33845524970
-
Transforming growth factor-beta in cancer and metastasis
-
Jakowlew SB. Transforming growth factor-beta in cancer and metastasis. Cancer Metastasis Rev 2006; 25: 435-57.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 435-457
-
-
Jakowlew, S.B.1
-
200
-
-
0031420122
-
Transforming growth factor-beta 1 overexpression produces lung resistance in vivo: Reversal by decorin
-
Teicher BA, Ikebe M, Ara G, Keyes SR, Herbst RS. Transforming growth factor-beta 1 overexpression produces lung resistance in vivo: reversal by decorin. In vivo 1997; 11: 463-73.
-
(1997)
In vivo
, vol.11
, pp. 463-473
-
-
Teicher, B.A.1
Ikebe, M.2
Ara, G.3
Keyes, S.R.4
Herbst, R.S.5
-
201
-
-
0037434552
-
Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
-
Baert F, Noman M, Vermeire S, Van Assche G, D'Haens G, Carbonez A, et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med 2003; 348: 601-8.
-
(2003)
N Engl J Med
, vol.348
, pp. 601-608
-
-
Baert, F.1
Noman, M.2
Vermeire, S.3
Van Assche, G.4
D'Haens, G.5
Carbonez, A.6
-
202
-
-
33846855387
-
Imaging and serum analysis of immune complex formation of radiolabelled Infliximab and anti-Infliximab in responders and non-responders to therapy for rheumatoid arthritis
-
van der Laken CJ, Voskuyl AE, Roos JC, van Walsum MS, de Groot ER, Wolbink G, et al. Imaging and serum analysis of immune complex formation of radiolabelled Infliximab and anti-Infliximab in responders and non-responders to therapy for rheumatoid arthritis. Ann Rheum Dis 2007; 66: 253-6.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 253-256
-
-
van der Laken, C.J.1
Voskuyl, A.E.2
Roos, J.C.3
van Walsum, M.S.4
de Groot, E.R.5
Wolbink, G.6
-
203
-
-
38549176118
-
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
-
Tracey D, Klareskog L, Sasso EHS, Jochen G, Tak PP. Tumor necrosis factor antagonist mechanisms of action: A comprehensive review. Pharmacol. Ther 2008; 117: 244-79.
-
(2008)
Pharmacol. Ther
, vol.117
, pp. 244-279
-
-
Tracey, D.1
Klareskog, L.2
Sasso, E.H.S.3
Jochen, G.4
Tak, P.P.5
-
204
-
-
0036796777
-
Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: A phase II double-blinded, randomized, dose-escalating trial
-
Choy EHS, Hazleman B, Smith M, Moss K, Lisi L, Scott DGI, et al. Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: A phase II double-blinded, randomized, dose-escalating trial. Rheumatology (Oxford) 2002; 41: 1133-7.
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 1133-1137
-
-
Choy, E.H.S.1
Hazleman, B.2
Smith, M.3
Moss, K.4
Lisi, L.5
Scott, D.G.I.6
-
205
-
-
11144318616
-
Intravenous CDP870, a PEGylated Fab' fragment of a humanized anti-tumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: An exploratory study
-
Winter TA, Wright J, Ghosh S, Jahnsen J, Innes A, Round P. Intravenous CDP870, a PEGylated Fab' fragment of a humanized anti-tumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: An exploratory study. Aliment Pharmacol Ther 2004; 20: 1337-46.
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 1337-1346
-
-
Winter, T.A.1
Wright, J.2
Ghosh, S.3
Jahnsen, J.4
Innes, A.5
Round, P.6
-
206
-
-
34447515607
-
Maintenance therapy with Certolizumab Pegol for Crohn's disease
-
Schreiber S, Khaliq-Kareemi M, Lawrance IC, Thomsen OO, Hanauer SB, McColm J, et al. Maintenance therapy with Certolizumab Pegol for Crohn's disease. N Engl J Med 2007; 357: 239-50.
-
(2007)
N Engl J Med
, vol.357
, pp. 239-250
-
-
Schreiber, S.1
Khaliq-Kareemi, M.2
Lawrance, I.C.3
Thomsen, O.O.4
Hanauer, S.B.5
McColm, J.6
-
207
-
-
55849112632
-
Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis
-
Keystone EC, Van der Heijde D, Mason D, Landewé R, Van Vollenhoven RF, Combe B, et al. Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis. Arthritis and Rheumatism 2008; 58: 3319-29.
-
(2008)
Arthritis and Rheumatism
, vol.58
, pp. 3319-3329
-
-
Keystone, E.C.1
Van der Heijde, D.2
Mason, D.3
Landewé, R.4
Van Vollenhoven, R.F.5
Combe, B.6
-
208
-
-
34447523749
-
Certolizumab Pegol for the treatment of Crohn's disease
-
Sandborn WJ, Feagan BG, Stoinov S, Honiball PJ, Rutgeerts P, Mason D, et al. Certolizumab Pegol for the treatment of Crohn's disease. J Exp Med 2007; 357: 228-38.
-
(2007)
J Exp Med
, vol.357
, pp. 228-238
-
-
Sandborn, W.J.1
Feagan, B.G.2
Stoinov, S.3
Honiball, P.J.4
Rutgeerts, P.5
Mason, D.6
-
209
-
-
68449085172
-
-
EULAR. Paris, France, June 11-14
-
Mease PJ, Keystone ECM, D, Smolen J, Schiff MH. Safety of Certolizumab Pegol with methotrexate in patients with active rheumatoid arthritis. EULAR. Paris, France. 2008; June 11-14
-
(2008)
Safety of Certolizumab Pegol with methotrexate in patients with active rheumatoid arthritis
-
-
Mease, P.J.1
Keystone2
ECM, D.3
Smolen, J.4
Schiff, M.H.5
-
210
-
-
68449096299
-
-
van Vollenhoven RF, Felson D, Weinblatt ME, Strand V, Mason D, Luitjens K, et al. ACR-Hybrid analysis confirms benefit of Certolizumab Pegol with methotrexate in patients with rheumatoid arthritis: Data from the RAPID 1 and 2 trials. EULAR. Paris, France. 2008; June 11-14
-
van Vollenhoven RF, Felson D, Weinblatt ME, Strand V, Mason D, Luitjens K, et al. ACR-Hybrid analysis confirms benefit of Certolizumab Pegol with methotrexate in patients with rheumatoid arthritis: Data from the RAPID 1 and 2 trials. EULAR. Paris, France. 2008; June 11-14
-
-
-
-
211
-
-
42449157502
-
Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: A randomized, double-blind, placebo-controlled dose-ranging study
-
Kay J, Matteson EL, Dasgupta B, Nash P, Durez P, Hall S, et al. Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: A randomized, double-blind, placebo-controlled dose-ranging study. Arthritis Rheum 2008; 58: 964-75.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 964-975
-
-
Kay, J.1
Matteson, E.L.2
Dasgupta, B.3
Nash, P.4
Durez, P.5
Hall, S.6
-
212
-
-
67449148036
-
-
EULAR, Paris, France, June 11-14
-
Emery P, Fleischmann RM, Moreland LW, Hsia EC, Strusberg I, Durez P, et al. [THU-0138] Golimumab (GLM), a new human anti-TNF-alpha monoclonal antibody, administered subcutaneously (sc) every 4 weeks in methotrexate-naïve patients with active rheumatoid arthritis (RA): A randomized, double-blind, placebo-controlled, GO-BEFORE study. EULAR 2008. Paris, France. 2008; June 11-14
-
(2008)
THU-0138] Golimumab (GLM), a new human anti-TNF-alpha monoclonal antibody, administered subcutaneously (sc) every 4 weeks in methotrexate-naïve patients with active rheumatoid arthritis (RA): A randomized, double-blind, placebo-controlled, GO-BEFORE study
-
-
Emery, P.1
Fleischmann, R.M.2
Moreland, L.W.3
Hsia, E.C.4
Strusberg, I.5
Durez, P.6
-
213
-
-
66149177508
-
Golimumab, a human antibody to TNF{alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate: The GO-FORWARD Study
-
Epub ahead of print
-
Keystone EC, Genovese MC, Klareskog L, Hsia EC, Hall S, Miranda PC, et al. Golimumab, a human antibody to TNF{alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate: The GO-FORWARD Study. Ann Rheum Dis 2008: Epub ahead of print.
-
(2008)
Ann Rheum Dis
-
-
Keystone, E.C.1
Genovese, M.C.2
Klareskog, L.3
Hsia, E.C.4
Hall, S.5
Miranda, P.C.6
-
214
-
-
54349105781
-
Golimumab, a new human anti-TNF-alpha monoclonal antibody, subcutaneously administered every 4 weeks in patients with active rheumatoid arthritis who were previously treated with anti-TNF-alpha agent(s): Results of the randomized, doubleblind, placebo-controlled trial
-
Smolen J, Kay J, Doyle MK, Landewe R, Matteson EL, Wollenhaupt J, et al. Golimumab, a new human anti-TNF-alpha monoclonal antibody, subcutaneously administered every 4 weeks in patients with active rheumatoid arthritis who were previously treated with anti-TNF-alpha agent(s): Results of the randomized, doubleblind, placebo-controlled trial. Ann Rheum Dis 2008; 67 (Suppl II): 50.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.SUPPL. II
, pp. 50
-
-
Smolen, J.1
Kay, J.2
Doyle, M.K.3
Landewe, R.4
Matteson, E.L.5
Wollenhaupt, J.6
-
215
-
-
33845482745
-
-
Chen Y-F, Jobanputra P, Barton P, Jowett S, Bryan S, Clark W, et al. A systematic review of the effectiveness of Adalimumab, Etanercept and Infliximab for the treatment of rheumatoid arthritis in adults and an economical evaluation of their cost-effectiveness. Health Technol Assess 2006; 10: Iii-iv, xi-xiii, 1-229.
-
Chen Y-F, Jobanputra P, Barton P, Jowett S, Bryan S, Clark W, et al. A systematic review of the effectiveness of Adalimumab, Etanercept and Infliximab for the treatment of rheumatoid arthritis in adults and an economical evaluation of their cost-effectiveness. Health Technol Assess 2006; 10: Iii-iv, xi-xiii, 1-229.
-
-
-
-
216
-
-
33746345358
-
Risks and benefits of Infliximab for the treatment of Crohn's disease
-
Siegel CA, Hur C, Korzenik JR, Gazelle GS, Sands BE. Risks and benefits of Infliximab for the treatment of Crohn's disease. Clin Gastroenterol Hepatol 2006; 4: 1017-24.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 1017-1024
-
-
Siegel, C.A.1
Hur, C.2
Korzenik, J.R.3
Gazelle, G.S.4
Sands, B.E.5
-
217
-
-
36549063053
-
Infliximab dose escalation vs. initiation of Adalimumab for loss of response in Crohn's disease: A cost-effectiveness analysis
-
Kaplan GG, Hur C, Korzenick JR, Sands BE. Infliximab dose escalation vs. initiation of Adalimumab for loss of response in Crohn's disease: A cost-effectiveness analysis. Aliment Pharmacol Ther 2007; 26: 1509-20.
-
(2007)
Aliment Pharmacol Ther
, vol.26
, pp. 1509-1520
-
-
Kaplan, G.G.1
Hur, C.2
Korzenick, J.R.3
Sands, B.E.4
-
218
-
-
37249063841
-
TNFalpha blockade in human diseases: An overview of efficacy and safety
-
Lin J, Ziring D, Desai S, Kim S, Kim S, WOng M, et al. TNFalpha blockade in human diseases: An overview of efficacy and safety. Clin Immunol 2008; 126: 13-30.
-
(2008)
Clin Immunol
, vol.126
, pp. 13-30
-
-
Lin, J.1
Ziring, D.2
Desai, S.3
Kim, S.4
Kim, S.5
WOng, M.6
-
219
-
-
25444482353
-
Tumor necrosis factor inhibitor therapy for rheumatoid arthritis
-
Naguwa SM. Tumor necrosis factor inhibitor therapy for rheumatoid arthritis. Ann N Y Acad Sci 2005; 1051: 709-15.
-
(2005)
Ann N Y Acad Sci
, vol.1051
, pp. 709-715
-
-
Naguwa, S.M.1
-
220
-
-
37349006854
-
The number needed to treat for Adalimumab, Etanercept, and Infliximab based on ACR50 response in three randomized controlled trials on established rheumatoid arthritis: A systematic literature review
-
Kristensen LEC, R, Bliddal H, Geborek P, Danneskiold-Samsoe BS, T. The number needed to treat for Adalimumab, Etanercept, and Infliximab based on ACR50 response in three randomized controlled trials on established rheumatoid arthritis: A systematic literature review. Scand J Rheumatol 2007; 36: 411-7.
-
(2007)
Scand J Rheumatol
, vol.36
, pp. 411-417
-
-
Kristensen1
LEC, R.2
Bliddal, H.3
Geborek, P.4
Danneskiold-Samsoe, B.T.5
-
221
-
-
34447318083
-
The efficacy of inhibiting tumour necrosis factor alpha and interleukin 1 in patients with rheumatoid arthritis: A meta-analysis and adjusted indirect comparisons
-
Nixon R, Bansback N, Brennan A. The efficacy of inhibiting tumour necrosis factor alpha and interleukin 1 in patients with rheumatoid arthritis: A meta-analysis and adjusted indirect comparisons. Rheumatology (Oxford) 2007; 46: 1140-7.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 1140-1147
-
-
Nixon, R.1
Bansback, N.2
Brennan, A.3
-
222
-
-
0142124920
-
Role of Infliximab in the treatment of early rheumatoid arthritis
-
Keystone EC, Haraoui BB, V. P. Role of Infliximab in the treatment of early rheumatoid arthritis. Clin Exp Rheumatol 2003; 21: S200-2.
-
(2003)
Clin Exp Rheumatol
, vol.21
-
-
Keystone, E.C.1
Haraoui, B.V.P.2
-
223
-
-
19944431840
-
Very early treatment with Infliximab in addition to methtrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after Infliximab withdrawal
-
Quinn MA, Conaghan PG, O'Connor PJ, Karim Z, Greenstein A, Brown A, et al. Very early treatment with Infliximab in addition to methtrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after Infliximab withdrawal. Arthritis Rheum 2005; 52: 27-35.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 27-35
-
-
Quinn, M.A.1
Conaghan, P.G.2
O'Connor, P.J.3
Karim, Z.4
Greenstein, A.5
Brown, A.6
-
224
-
-
47249149102
-
Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs
-
Epub ahead of print
-
Sizova L. Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs. Brit J Clin Pharmacol 2008: Epub ahead of print.
-
(2008)
Brit J Clin Pharmacol
-
-
Sizova, L.1
-
225
-
-
37849052961
-
TNFalpha blockade in human diseases: Mechanisms and future directions
-
Wong M, Ziring D, Korin Y, Desai S, Kim S, Lin J, et al. TNFalpha blockade in human diseases: Mechanisms and future directions. Clin Immunol 2008; 126: 121-36.
-
(2008)
Clin Immunol
, vol.126
, pp. 121-136
-
-
Wong, M.1
Ziring, D.2
Korin, Y.3
Desai, S.4
Kim, S.5
Lin, J.6
-
226
-
-
34248546506
-
Effects of Etanercept are distinct from Infliximab in modulating proinflammatory genes in activated human leukocytes
-
Haider AS, Cardinale IR, Whynot JA, Krueger JG. Effects of Etanercept are distinct from Infliximab in modulating proinflammatory genes in activated human leukocytes. J Investig Dermatol Symp Proc 2007; 12: 9-15.
-
(2007)
J Investig Dermatol Symp Proc
, vol.12
, pp. 9-15
-
-
Haider, A.S.1
Cardinale, I.R.2
Whynot, J.A.3
Krueger, J.G.4
-
227
-
-
0037331223
-
Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents
-
Slifman NR, Gershon SK, Lee J-H, Edwards ET, Braun MM. Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents. Arthritis Rheum 2003; 48: 319-24.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 319-324
-
-
Slifman, N.R.1
Gershon, S.K.2
Lee, J.-H.3
Edwards, E.T.4
Braun, M.M.5
-
228
-
-
0036822552
-
Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists Infliximab and Etanercept
-
Lee J-H, Slifman NR, Gershon SK, Edwards ET, Schwieterman WD, Siegel JN, et al. Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists Infliximab and Etanercept. Arthritis Rheum 2002; 46: 2565-70.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2565-2570
-
-
Lee, J.-H.1
Slifman, N.R.2
Gershon, S.K.3
Edwards, E.T.4
Schwieterman, W.D.5
Siegel, J.N.6
-
230
-
-
2542476069
-
Associations between rheumatoid arthritis and malignancy
-
Chakravarty EF, Genovese MC. Associations between rheumatoid arthritis and malignancy. Rheum Dis Clin North Am 2004; 30: 271-84.
-
(2004)
Rheum Dis Clin North Am
, vol.30
, pp. 271-284
-
-
Chakravarty, E.F.1
Genovese, M.C.2
-
231
-
-
33644892763
-
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
-
Baecklund E, Iliadou A, Askling J, Ekbom A, Backlin C, Granath F, et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum 2006; 54: 692-701.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 692-701
-
-
Baecklund, E.1
Iliadou, A.2
Askling, J.3
Ekbom, A.4
Backlin, C.5
Granath, F.6
-
232
-
-
44049085950
-
A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis
-
Smitten AL, Simon TA, Hochberg MC, Suissa S. A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis. Arthritis Res Ther 2008; 10: R45.
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Smitten, A.L.1
Simon, T.A.2
Hochberg, M.C.3
Suissa, S.4
-
233
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 2006; 295: 2275-85.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
234
-
-
33744495746
-
Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice
-
den Broeder AA, de Jong E, Franssen MJAM, Jeurissen MEC, Flendrie M, van den Hoogen FHJ. Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice. Ann Rheum Dis 2006; 65: 760-62.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 760-762
-
-
den Broeder, A.A.1
de Jong, E.2
Franssen, M.J.A.M.3
Jeurissen, M.E.C.4
Flendrie, M.5
van den Hoogen, F.H.J.6
-
235
-
-
0037389680
-
Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis
-
Fleischmann RM, Schechtman J, Bennett R, Handel ML, Burmester G, Tesser J, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis. Arthritis Rheum 2003; 48: 927-34.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 927-934
-
-
Fleischmann, R.M.1
Schechtman, J.2
Bennett, R.3
Handel, M.L.4
Burmester, G.5
Tesser, J.6
-
236
-
-
33746578466
-
Safety of extended treatment with anakinra in patients with rheumatoid arthritis
-
Fleischmann RM, Tesser J, Schiff MH, Schechtman J, Burmester G, Bennett R, et al. Safety of extended treatment with anakinra in patients with rheumatoid arthritis. Ann Rheum Dis 2006; 65: 1006- 12.
-
Ann Rheum Dis 2006; 65: 1006- 12
-
-
Fleischmann, R.M.1
Tesser, J.2
Schiff, M.H.3
Schechtman, J.4
Burmester, G.5
Bennett, R.6
-
237
-
-
46149124721
-
Risk of serious infection during Rituximab, Abatacept and Anakinra therapies for rheumatoid arthritis: Meta-analyses of randomized placebo-controlled trials
-
Epub ahead of print
-
Salliot C, Dougados M, Gossec L. Risk of serious infection during Rituximab, Abatacept and Anakinra therapies for rheumatoid arthritis: meta-analyses of randomized placebo-controlled trials. Ann Rheum Dis 2008: Epub ahead of print.
-
(2008)
Ann Rheum Dis
-
-
Salliot, C.1
Dougados, M.2
Gossec, L.3
-
239
-
-
0033538468
-
BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
-
Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, et al. BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999; 285: 260-3.
-
(1999)
Science
, vol.285
, pp. 260-263
-
-
Moore, P.A.1
Belvedere, O.2
Orr, A.3
Pieri, K.4
LaFleur, D.W.5
Feng, P.6
-
240
-
-
0032555931
-
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
-
Hahne M, Kataoka T, Schröter M, Hofmann K, Irmler M, Bodmer J-L, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med 1998; 188: 1185-90.
-
(1998)
J Exp Med
, vol.188
, pp. 1185-1190
-
-
Hahne, M.1
Kataoka, T.2
Schröter, M.3
Hofmann, K.4
Irmler, M.5
Bodmer, J.-L.6
-
241
-
-
33750341510
-
-
Cancro MP. The BLyS/BAFF family of ligands and receptors: Key targets in the therapy and understanding of autoimmunity. Ann Rheum Dis 2006; 65: iii34-6.
-
Cancro MP. The BLyS/BAFF family of ligands and receptors: Key targets in the therapy and understanding of autoimmunity. Ann Rheum Dis 2006; 65: iii34-6.
-
-
-
-
242
-
-
0035167632
-
Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
-
Zhang J, Roschke V, Baker KP, Wang Z, Alarcon GS, Fessler BJ, et al. Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001; 166: 6-10.
-
(2001)
J Immunol
, vol.166
, pp. 6-10
-
-
Zhang, J.1
Roschke, V.2
Baker, K.P.3
Wang, Z.4
Alarcon, G.S.5
Fessler, B.J.6
-
244
-
-
33646367770
-
OP-1920] Belimumab (BmAb), a fully human monoclonal antibody to B-lymphocyte stimulator (BLyS), combined with standard of care therapy reduces the signs and symptoms of rheumatoid arthritis in a heterogenous subject population
-
San Diego, Calif, Nov 16
-
McKay J, Chwalinska-Sadowska H, Boling E, Valente R, Limanni A, Racewicz A, et al. [OP-1920] Belimumab (BmAb), a fully human monoclonal antibody to B-lymphocyte stimulator (BLyS), combined with standard of care therapy reduces the signs and symptoms of rheumatoid arthritis in a heterogenous subject population. 69th Annual Meeting of the American College of Rheumatology. San Diego, Calif. 2005; Nov 16
-
(2005)
69th Annual Meeting of the American College of Rheumatology
-
-
McKay, J.1
Chwalinska-Sadowska, H.2
Boling, E.3
Valente, R.4
Limanni, A.5
Racewicz, A.6
-
245
-
-
43649094546
-
Belimumab: Anti-BLyS human monoclonal antibody, anti-BLyS monoclonal antibody, BmAb, Human monoclonal antibody to B-Lymphocyte stimulator
-
No-authors-listed. Belimumab: Anti-BLyS human monoclonal antibody, anti-BLyS monoclonal antibody, BmAb, Human monoclonal antibody to B-Lymphocyte stimulator. Drugs in R&D 2008; 9: 197-202.
-
Drugs in R&D 2008
, vol.9
, pp. 197-202
-
-
No-authors-listed1
-
246
-
-
33749426139
-
The price of sight - Ranibizumab, Bevacizumab, and the treatment of macular degeneration
-
Steinbrook R. The price of sight - Ranibizumab, Bevacizumab, and the treatment of macular degeneration. N Engl J Med 2006; 355: 1409-12.
-
(2006)
N Engl J Med
, vol.355
, pp. 1409-1412
-
-
Steinbrook, R.1
-
247
-
-
16644377775
-
Overview of Bevacizumab: A new cancer therapeutic strategy targeting vascular endothelial growth factor
-
Ignoffo RJ. Overview of Bevacizumab: A new cancer therapeutic strategy targeting vascular endothelial growth factor. Am J Health Syst Pharm 2004; 61: S21-6.
-
(2004)
Am J Health Syst Pharm
, vol.61
-
-
Ignoffo, R.J.1
-
248
-
-
33845961014
-
Bevacizumab: An angiogenesis inhibitor for the treatment of solid malignancies
-
Shih T, Lindley C. Bevacizumab: An angiogenesis inhibitor for the treatment of solid malignancies. Clin Ther 2006; 28: 1779-802.
-
(2006)
Clin Ther
, vol.28
, pp. 1779-1802
-
-
Shih, T.1
Lindley, C.2
-
249
-
-
47949089077
-
VEGF-targeted therapy: Mechanisms of antitumour activity
-
Ellis LM, Hicklin DJ. VEGF-targeted therapy: Mechanisms of antitumour activity. Nat Rev Cancer 2008; 8: 579-91.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 579-591
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
250
-
-
36049026182
-
Role of anti-angiogenesis agents in treating NSCLC: Focus on Bevacizumab and VEGFR tyrosine kinase inhibitors
-
Cabebe E, Wakelee H. Role of anti-angiogenesis agents in treating NSCLC: focus on Bevacizumab and VEGFR tyrosine kinase inhibitors. Curr Treat Options Oncol 2007; 8: 15-27.
-
(2007)
Curr Treat Options Oncol
, vol.8
, pp. 15-27
-
-
Cabebe, E.1
Wakelee, H.2
-
252
-
-
34047219240
-
Recognizing and managing toxicities of molecular targeted therapies for colorectal cancer
-
Grothey A. Recognizing and managing toxicities of molecular targeted therapies for colorectal cancer. Oncology (Willinston Park) 2006; 20: 21-8.
-
(2006)
Oncology (Willinston Park)
, vol.20
, pp. 21-28
-
-
Grothey, A.1
-
253
-
-
43449111187
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomized, double-blind, placebo-controlled trial (PHOENIX 1)
-
Leonardi CL, Kimball AB, Papp KA, Yeilding N, Guzzo C, Wang Y, et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomized, double-blind, placebo-controlled trial (PHOENIX 1). Lancet 2008; 371: 1665-74.
-
(2008)
Lancet
, vol.371
, pp. 1665-1674
-
-
Leonardi, C.L.1
Kimball, A.B.2
Papp, K.A.3
Yeilding, N.4
Guzzo, C.5
Wang, Y.6
-
254
-
-
43449139402
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
Papp KA, Langley RG, Lebwohl M, Krueger GG, Szapary P, Yeilding N, et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet 2008; 371: 1675-84.
-
(2008)
Lancet
, vol.371
, pp. 1675-1684
-
-
Papp, K.A.1
Langley, R.G.2
Lebwohl, M.3
Krueger, G.G.4
Szapary, P.5
Yeilding, N.6
-
255
-
-
53049091561
-
A randomized trial of ustekinumab, a human interleukin-12/ 23 monoclonal antibody, in patients with moderate-tosevere Crohn's disease
-
Sandborn WJ. A randomized trial of ustekinumab, a human interleukin-12/ 23 monoclonal antibody, in patients with moderate-tosevere Crohn's disease. Gastroenterology 2008; 135: 1130-41.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
-
256
-
-
38149049065
-
Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines
-
Brasier AR, Victor S, Boetticher G, Ju H, Lee C, Bleecker ER, et al. Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines. J Allergy Clin Immunol 2008; 121: 30-7.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 30-37
-
-
Brasier, A.R.1
Victor, S.2
Boetticher, G.3
Ju, H.4
Lee, C.5
Bleecker, E.R.6
-
257
-
-
4444221246
-
Refractory eosinophilic airway inflammation in severe asthma
-
ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KFB, Elisabeth H. "Refractory" eosinophilic airway inflammation in severe asthma. Am J Respir Crit Care Med 2004; 170: 601-5.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 601-605
-
-
ten Brinke, A.1
Zwinderman, A.H.2
Sterk, P.J.3
Rabe, K.F.B.4
Elisabeth, H.5
-
258
-
-
0026684438
-
One-year follow-up of vaccine therapy in HIV-infected immune-deficient individuals: A new strategy
-
Zagury D, Bernard J, Halbreich A, Bizzini B, Carelli C, Achour A, et al. One-year follow-up of vaccine therapy in HIV-infected immune-deficient individuals: A new strategy. J Acquir Immune Defic Syndr Hum Retrovirol 1992; 5: 676-81.
-
(1992)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.5
, pp. 676-681
-
-
Zagury, D.1
Bernard, J.2
Halbreich, A.3
Bizzini, B.4
Carelli, C.5
Achour, A.6
-
259
-
-
0028170090
-
A randomized, placebo-controlled, blind anti-AIDS clinical trial: Safety and immunogenicity of a specific anti-IFN alpha immunization
-
Gringeri A, Santagostino E, Mannucci PM, Tradati F, Cultraro D, Buzzi A, et al. A randomized, placebo-controlled, blind anti-AIDS clinical trial: Safety and immunogenicity of a specific anti-IFN alpha immunization. J Acquir Immune Defic Syndr 1994; 7: 978-88.
-
(1994)
J Acquir Immune Defic Syndr
, vol.7
, pp. 978-988
-
-
Gringeri, A.1
Santagostino, E.2
Mannucci, P.M.3
Tradati, F.4
Cultraro, D.5
Buzzi, A.6
-
260
-
-
1542429111
-
Absence of clinical, virological, and immunological signs of progression in HIV-1 infected patients receiving active anti-interferon-[alpha] immunization: A 30-month follow-up report
-
Gringeri A, Santagostino E, Cusini M, Muça-Perja M, Marinoni A, Burny A, et al. Absence of clinical, virological, and immunological signs of progression in HIV-1 infected patients receiving active anti-interferon-[alpha] immunization: A 30-month follow-up report. J Acquir Immune Defic Syndr Hum Retrovirol 1996; 13: 55-67.
-
(1996)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.13
, pp. 55-67
-
-
Gringeri, A.1
Santagostino, E.2
Cusini, M.3
Muça-Perja, M.4
Marinoni, A.5
Burny, A.6
-
261
-
-
0033001847
-
Active anti-interferon-[alpha] immunization: A European-Israeli, randomized, double-blind, placebo-controlled clinical trial in 242 HIV-1 infected patients (the EURIS study)
-
Gringeri A, Musicco M, Hermans P, Bentwich Z, Cusini M, Bergamasco A, et al. Active anti-interferon-[alpha] immunization: A European-Israeli, randomized, double-blind, placebo-controlled clinical trial in 242 HIV-1 infected patients (the EURIS study). J Acquir Immune Defic Syndr Hum Retrovirol 1999; 20: 358-70.
-
(1999)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.20
, pp. 358-370
-
-
Gringeri, A.1
Musicco, M.2
Hermans, P.3
Bentwich, Z.4
Cusini, M.5
Bergamasco, A.6
-
262
-
-
0028143211
-
Randomized double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
-
Elliott MJ, Maini RN, Feldmann M, Kalden JR, Antoni CE, Smolen JS, et al. Randomized double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994; 344: 1105-10.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Kalden, J.R.4
Antoni, C.E.5
Smolen, J.S.6
-
263
-
-
0037379605
-
Active versus passive anti-cytokine antibody therapy against cytokine-associated chronic diseases
-
Zagury D, Le Buanec H, Bizzini B, Burny A, Lewis G, Gallo RC. Active versus passive anti-cytokine antibody therapy against cytokine-associated chronic diseases. Cytokine Growth Factor Rev 2003; 14: 123-37.
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 123-137
-
-
Zagury, D.1
Le Buanec, H.2
Bizzini, B.3
Burny, A.4
Lewis, G.5
Gallo, R.C.6
-
264
-
-
0024834224
-
Interleukin-1-inhibitory IgG in sera from some patients with rheumatoid arthritis
-
Suzuki H, Akama T, Okane M, Kono I, Matsui Y, Yamane K, et al. Interleukin-1-inhibitory IgG in sera from some patients with rheumatoid arthritis. Arthritis Rheum 1989; 32: 1528-38.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 1528-1538
-
-
Suzuki, H.1
Akama, T.2
Okane, M.3
Kono, I.4
Matsui, Y.5
Yamane, K.6
-
265
-
-
0024588193
-
IgG autoanti-bodies against interleukin 1alpha in sera of normal individuals
-
Svenson M, Poulsen LK, Fomsgaard A, Bendtzen K. IgG autoanti-bodies against interleukin 1alpha in sera of normal individuals. Scand J Immunol 1989; 29: 489-92.
-
(1989)
Scand J Immunol
, vol.29
, pp. 489-492
-
-
Svenson, M.1
Poulsen, L.K.2
Fomsgaard, A.3
Bendtzen, K.4
-
266
-
-
0025225511
-
Distribution and characterization of autoantibodies to interleukin 1alpha in normal human sera
-
Svenson M, Hansen MB, Bendtzen K. Distribution and characterization of autoantibodies to interleukin 1alpha in normal human sera. Scand J Immunol 1990; 32: 695-701.
-
(1990)
Scand J Immunol
, vol.32
, pp. 695-701
-
-
Svenson, M.1
Hansen, M.B.2
Bendtzen, K.3
-
267
-
-
0025049877
-
Autoantibodies to crude human leucocyte interferon (IFN), native human IFN, recombinant human IFN-alpha 2b and human IFN-gamma in healthy blood donnors
-
Ross C, Hansen MBS, T, Berg K. Autoantibodies to crude human leucocyte interferon (IFN), native human IFN, recombinant human IFN-alpha 2b and human IFN-gamma in healthy blood donnors. Clin Exp Immunol 1990; 82: 57-62.
-
(1990)
Clin Exp Immunol
, vol.82
, pp. 57-62
-
-
Ross, C.1
Hansen2
MBS, T.3
Berg, K.4
-
268
-
-
0032521450
-
Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations
-
Svenson M, Hansen MB, Ross C, Diamant M, Rieneck K, Nielsen H, et al. Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations. Blood 1998; 91: 2054-61.
-
(1998)
Blood
, vol.91
, pp. 2054-2061
-
-
Svenson, M.1
Hansen, M.B.2
Ross, C.3
Diamant, M.4
Rieneck, K.5
Nielsen, H.6
-
269
-
-
0008557173
-
-
Peter J, Shoenfeld Y Ed, Amsterdam, Elsevier Science B.V
-
Bendtzen K, Hansen MB, Ross C, Svenson M. In: Peter J, Shoenfeld Y Ed, Autoantibodies. Amsterdam, Elsevier Science B.V. 1996, 209-16.
-
Autoantibodies
, vol.1996
, pp. 209-216
-
-
Bendtzen, K.1
Hansen, M.B.2
Ross, C.3
Svenson, M.4
-
271
-
-
0345358581
-
Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity
-
Wildbaum G, Nahir MA, Karin N. Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity. Immunity 2003; 19: 679-88.
-
(2003)
Immunity
, vol.19
, pp. 679-688
-
-
Wildbaum, G.1
Nahir, M.A.2
Karin, N.3
-
272
-
-
0034940764
-
Toward a new generation of vaccines: The anti-cytokine therapeutic vaccines
-
Zagury D, Burny A, Gallo RC. Toward a new generation of vaccines: The anti-cytokine therapeutic vaccines. PNAS 2001; 98: 8024-9.
-
(2001)
PNAS
, vol.98
, pp. 8024-8029
-
-
Zagury, D.1
Burny, A.2
Gallo, R.C.3
-
273
-
-
0842348085
-
Anti-cytokine Ab immune therapy: Present status and perspectives
-
Zagury D, Gallo RC. Anti-cytokine Ab immune therapy: Present status and perspectives. Drug Discov Today 2004; 9: 72-81.
-
(2004)
Drug Discov Today
, vol.9
, pp. 72-81
-
-
Zagury, D.1
Gallo, R.C.2
-
274
-
-
0344046620
-
Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons
-
Gorin PD, Johnson EM. Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons. PNAS 1979; 76: 5382-6.
-
(1979)
PNAS
, vol.76
, pp. 5382-5386
-
-
Gorin, P.D.1
Johnson, E.M.2
-
275
-
-
0019161427
-
Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor
-
Johnson EMJ, Gorin PD, Brandeis LD, Pearson J. Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor. Science 1980; 210: 916-8.
-
(1980)
Science
, vol.210
, pp. 916-918
-
-
Johnson, E.M.J.1
Gorin, P.D.2
Brandeis, L.D.3
Pearson, J.4
-
276
-
-
0028985817
-
Fetal effects of epidermal growth factor deficiency induced in rats by autoantibodies against epidermal growth factor
-
Raaberg L, Nexo E, Jorgensen PE, Poulsen SS, Jakab M. Fetal effects of epidermal growth factor deficiency induced in rats by autoantibodies against epidermal growth factor. Pediatr Res 1995; 37: 175-81.
-
(1995)
Pediatr Res
, vol.37
, pp. 175-181
-
-
Raaberg, L.1
Nexo, E.2
Jorgensen, P.E.3
Poulsen, S.S.4
Jakab, M.5
-
277
-
-
3843101609
-
Active immunization against murine TNFalpha peptides in mice: Generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection
-
Capini CJ, Bertin-Maghit SM, Bessis N, Haumont PM, Bernier EM, Muel EG, et al. Active immunization against murine TNFalpha peptides in mice: Generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection. Vaccine 2004; 22: 3144-53.
-
(2004)
Vaccine
, vol.22
, pp. 3144-3153
-
-
Capini, C.J.1
Bertin-Maghit, S.M.2
Bessis, N.3
Haumont, P.M.4
Bernier, E.M.5
Muel, E.G.6
-
278
-
-
0034681145
-
Anti-IL9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice
-
Richard M, Grencis RK, Humphreys NE, Renauld J-C, Van Snick J. Anti-IL9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice. PNAS 2000; 97: 767-72.
-
(2000)
PNAS
, vol.97
, pp. 767-772
-
-
Richard, M.1
Grencis, R.K.2
Humphreys, N.E.3
Renauld, J.-C.4
Van Snick, J.5
-
279
-
-
1542316856
-
-
Zuany-Amorim CM, C, Dalum I, Jensen MR, Gautam A, Pay G, Mouritsen S, et al. Induction of TNF-alpha autoantibody production by AutoVac TNF106: A novel therapeutic approach for the treatment of allergic diseases. Int Arch Allergy Immunol 2004; 133: 154-63.
-
Zuany-Amorim CM, C, Dalum I, Jensen MR, Gautam A, Pay G, Mouritsen S, et al. Induction of TNF-alpha autoantibody production by AutoVac TNF106: A novel therapeutic approach for the treatment of allergic diseases. Int Arch Allergy Immunol 2004; 133: 154-63.
-
-
-
-
280
-
-
33751243318
-
Development of an anti-IL-17A autovaccine that prevents experimental auto-immune encephalomyelitis
-
Uyttenhove C, Van Snick J. Development of an anti-IL-17A autovaccine that prevents experimental auto-immune encephalomyelitis. Eur J Immunol 2006; 36: 2868-74.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2868-2874
-
-
Uyttenhove, C.1
Van Snick, J.2
-
281
-
-
40649119819
-
Early and long-lasting protection from arthritis in TNF-alpha transgenic mice vaccinated against TNF-alpha
-
Epub ahead of print
-
Delavallee L, Le Buanec H, Bessis N, Assier E, Denys A, Bizzini B, et al. Early and long-lasting protection from arthritis in TNF-alpha transgenic mice vaccinated against TNF-alpha. Ann Rheum Dis 2007: Epub ahead of print.
-
(2007)
Ann Rheum Dis
-
-
Delavallee, L.1
Le Buanec, H.2
Bessis, N.3
Assier, E.4
Denys, A.5
Bizzini, B.6
-
282
-
-
33847326301
-
VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases
-
Rad FH, Le Buanec H, Paturance S, Larcier P, Genne P, Ryffel B, et al. VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases. PNAS 2007; 104: 2837-42.
-
(2007)
PNAS
, vol.104
, pp. 2837-2842
-
-
Rad, F.H.1
Le Buanec, H.2
Paturance, S.3
Larcier, P.4
Genne, P.5
Ryffel, B.6
-
283
-
-
0033018740
-
Therapeutic antibodies elicited by immunization against TNF-alpha
-
Dalum I, Butler D, Jensen MR, Hindersson P, Steinaa LW, A. M, Grell SN, et al. Therapeutic antibodies elicited by immunization against TNF-alpha. Nat Biotechnol 1999; 17: 666-9.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 666-669
-
-
Dalum, I.1
Butler, D.2
Jensen, M.R.3
Hindersson, P.4
Steinaa5
LW, A.M.6
Grell, S.N.7
-
284
-
-
1942437446
-
TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model
-
Waterston AMS, F, Andreakos EB, D. M, Feldmann MC, R. C. TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model. Br J Cancer 2004; 90: 1279-84.
-
(2004)
Br J Cancer
, vol.90
, pp. 1279-1284
-
-
Waterston1
AMS, F.2
Andreakos3
EB, D.M.4
Feldmann5
MC, R.C.6
-
285
-
-
22244450013
-
Phase I study of TNFalpha autovaccine in patients with metastatic cancer
-
Waterston AM, Gumbrell L, Bratt T, Waller S, Gustav-Aspland J, Highley M, et al. Phase I study of TNFalpha autovaccine in patients with metastatic cancer. Cancer Immunol Immunother 2005; 54: 848-57.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 848-857
-
-
Waterston, A.M.1
Gumbrell, L.2
Bratt, T.3
Waller, S.4
Gustav-Aspland, J.5
Highley, M.6
-
286
-
-
43249129316
-
Amelioration of experimental autoimmune encephalomyelitis by BLyS autovaccine
-
Xue X, Feng G, Li M, Qin X, Wu S, Zhang C, et al. Amelioration of experimental autoimmune encephalomyelitis by BLyS autovaccine. Vaccine 2008; 26: 2873-81.
-
(2008)
Vaccine
, vol.26
, pp. 2873-2881
-
-
Xue, X.1
Feng, G.2
Li, M.3
Qin, X.4
Wu, S.5
Zhang, C.6
-
287
-
-
33751254750
-
Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis
-
Röhn TA, Jennings GT, Hernandez M, Grest P, Beck M, Zou Y, et al. Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis. Eur J Immunol 2006; 36: 2857-67.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2857-2867
-
-
Röhn, T.A.1
Jennings, G.T.2
Hernandez, M.3
Grest, P.4
Beck, M.5
Zou, Y.6
-
288
-
-
0026579897
-
Genetic immunization is a simple method for eliciting an immune response
-
Tang D-c, DeVit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature 1992; 356: 152-4.
-
(1992)
Nature
, vol.356
, pp. 152-154
-
-
Tang, D.-C.1
DeVit, M.2
Johnston, S.A.3
-
289
-
-
68449088304
-
-
In: Paul WE Ed, Fundamental Immunology. Philadelphia, Lippincott Williams & Wilkins. 2003, 1331-2.
-
In: Paul WE Ed, Fundamental Immunology. Philadelphia, Lippincott Williams & Wilkins. 2003, 1331-2.
-
-
-
-
290
-
-
0032794139
-
Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines
-
Youssef S, Wildbaum G, Karin N. Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines. J Autoimmun 1999; 13: 21-9.
-
(1999)
J Autoimmun
, vol.13
, pp. 21-29
-
-
Youssef, S.1
Wildbaum, G.2
Karin, N.3
-
291
-
-
0033818187
-
A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritis
-
Wildbaum G, Youssef S, Karin N. A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritis. J Clin Invest 2000; 106: 671-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 671-679
-
-
Wildbaum, G.1
Youssef, S.2
Karin, N.3
-
292
-
-
0033818187
-
A targeted DNA vaccine encoding Fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis
-
Wildbaum G, Westermann J, Maor G, Karin N. A targeted DNA vaccine encoding Fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis. J Clin Invest 2000; 106: 671-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 671-679
-
-
Wildbaum, G.1
Westermann, J.2
Maor, G.3
Karin, N.4
-
293
-
-
0038376618
-
TNFalpha DNA vaccination prevents clinical manifestations of experimental antiphospholipid syndrome
-
Blank M, Krause I, Wildbaum G, Karin N, Shoenfeld Y. TNFalpha DNA vaccination prevents clinical manifestations of experimental antiphospholipid syndrome. Lupus 2003; 12: 546-9.
-
(2003)
Lupus
, vol.12
, pp. 546-549
-
-
Blank, M.1
Krause, I.2
Wildbaum, G.3
Karin, N.4
Shoenfeld, Y.5
-
294
-
-
0032532308
-
Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines
-
Youssef S, Wildbaum G, Maor G, Lanir N, Gour-Lavie A, Grabie N, et al. Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines. J Immunol 1998; 161: 3870-9.
-
(1998)
J Immunol
, vol.161
, pp. 3870-3879
-
-
Youssef, S.1
Wildbaum, G.2
Maor, G.3
Lanir, N.4
Gour-Lavie, A.5
Grabie, N.6
-
295
-
-
0033846366
-
C-C chemokine-encoding DNA vaccines ehnance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis
-
Youssef S, Maor G, Wildbaum G, Grabie N, Gour-Lavie A, Karin N. C-C chemokine-encoding DNA vaccines ehnance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis. J Clin Invest 2000; 106: 361-71.
-
(2000)
J Clin Invest
, vol.106
, pp. 361-371
-
-
Youssef, S.1
Maor, G.2
Wildbaum, G.3
Grabie, N.4
Gour-Lavie, A.5
Karin, N.6
-
296
-
-
0036721708
-
Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis
-
Salomon I, Netzer N, Wildbaum G, Schif-Zuck S, Maor G, Karin N. Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis. J Immunol 2002; 169: 2685-93.
-
(2002)
J Immunol
, vol.169
, pp. 2685-2693
-
-
Salomon, I.1
Netzer, N.2
Wildbaum, G.3
Schif-Zuck, S.4
Maor, G.5
Karin, N.6
-
297
-
-
0034897403
-
Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway
-
Garren H, Ruiz PJ, Watkins TA, Fontoura P, Nguyen L-V, Estline ER, et al. Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway. Immunity 2001; 15: 15-22.
-
(2001)
Immunity
, vol.15
, pp. 15-22
-
-
Garren, H.1
Ruiz, P.J.2
Watkins, T.A.3
Fontoura, P.4
Nguyen, L.-V.5
Estline, E.R.6
-
298
-
-
33751580722
-
Coadministration of plasmid DNA constructs encoding an encephalitogenic determinant and IL-10 elicits regulatory T cell-mediated protective immunity in the central nervous system
-
Schif-Zuck S, Wildbaum G, Karin N. Coadministration of plasmid DNA constructs encoding an encephalitogenic determinant and IL-10 elicits regulatory T cell-mediated protective immunity in the central nervous system. J Immunol 2006; 177: 8241-7.
-
(2006)
J Immunol
, vol.177
, pp. 8241-8247
-
-
Schif-Zuck, S.1
Wildbaum, G.2
Karin, N.3
-
299
-
-
0035478849
-
Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma
-
Hertz M, Mahalingam S, Dalum I, Klysner S, Mattes J, Neisig A, et al. Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma. J Immunol 2001; 167: 3792-9.
-
(2001)
J Immunol
, vol.167
, pp. 3792-3799
-
-
Hertz, M.1
Mahalingam, S.2
Dalum, I.3
Klysner, S.4
Mattes, J.5
Neisig, A.6
-
300
-
-
34447283518
-
Human TNF-alpha gene vaccination prevents collagen-induced arthritis in mice
-
Shen Y, Chen J, Zhang X, Wu X, Xu Q. Human TNF-alpha gene vaccination prevents collagen-induced arthritis in mice. Int Immunopharmacol 2007; 7: 1140-9.
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 1140-1149
-
-
Shen, Y.1
Chen, J.2
Zhang, X.3
Wu, X.4
Xu, Q.5
-
301
-
-
40949128356
-
A recombinant DNA plasmid encoding the human interleukin-5 breaks immunological tolerance and inhibits airway inflammation in a murine model of asthma
-
Tan GH, Su JMW, C. C, Huang FY, Wang H, Huang YH, Lin YY. A recombinant DNA plasmid encoding the human interleukin-5 breaks immunological tolerance and inhibits airway inflammation in a murine model of asthma. Int Arch Allergy Immunol 2008; 145: 313-23.
-
(2008)
Int Arch Allergy Immunol
, vol.145
, pp. 313-323
-
-
Tan, G.H.1
Su2
JMW, C.C.3
Huang, F.Y.4
Wang, H.5
Huang, Y.H.6
Lin, Y.Y.7
-
302
-
-
3843119002
-
Induction of protective therapy for autoimmune diseases by targeted DNA vaccines encoding pro-inflammatory cytokines and chemokines
-
Karin N. Induction of protective therapy for autoimmune diseases by targeted DNA vaccines encoding pro-inflammatory cytokines and chemokines. Curr Opin Mol Ther 2004; 6: 27-33.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 27-33
-
-
Karin, N.1
-
303
-
-
22144457874
-
Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling
-
Bertin-Maghit SM, Capini CJ, Bessis N, Chomilier J, Muller S, Abbas A, et al. Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling. Vaccine 2005; 23: 4228-35.
-
(2005)
Vaccine
, vol.23
, pp. 4228-4235
-
-
Bertin-Maghit, S.M.1
Capini, C.J.2
Bessis, N.3
Chomilier, J.4
Muller, S.5
Abbas, A.6
-
304
-
-
11144256552
-
Peptide immunogens designed to enhance immune responses against human immunodeficiency virus (HIV) mutant strains: A plausible means of preventing viral persistence
-
Hewer R, Meyer D. Peptide immunogens designed to enhance immune responses against human immunodeficiency virus (HIV) mutant strains: A plausible means of preventing viral persistence. J Theor Biol 2005; 233: 85-90.
-
(2005)
J Theor Biol
, vol.233
, pp. 85-90
-
-
Hewer, R.1
Meyer, D.2
-
305
-
-
0033104769
-
Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B)
-
Farris AD, Brown L, Reynolds P, Harley JB, James JA, Scofield RH, et al. Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B). J Immunol 1999; 162: 3079-87.
-
(1999)
J Immunol
, vol.162
, pp. 3079-3087
-
-
Farris, A.D.1
Brown, L.2
Reynolds, P.3
Harley, J.B.4
James, J.A.5
Scofield, R.H.6
-
306
-
-
37549034210
-
Multiple antigenic peptides as vaccine platform for the induction of humoral responses against Dengue-2 virus
-
Amexis G, Young NS. Multiple antigenic peptides as vaccine platform for the induction of humoral responses against Dengue-2 virus. Viral Immunol 2007; 20: 657-63.
-
(2007)
Viral Immunol
, vol.20
, pp. 657-663
-
-
Amexis, G.1
Young, N.S.2
-
307
-
-
34548437104
-
Novel recombinant interleukin-13 peptide-based vaccine reduces airway allergic inflammatory responses in mice
-
Ma Y, HayGlass KT, Becker AB, Fan Y, Yang X, Basu S, et al. Novel recombinant interleukin-13 peptide-based vaccine reduces airway allergic inflammatory responses in mice. Am J Respir Crit Care Med 2007; 176: 439-45.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 439-445
-
-
Ma, Y.1
HayGlass, K.T.2
Becker, A.B.3
Fan, Y.4
Yang, X.5
Basu, S.6
-
308
-
-
28244444594
-
Membrane tumor necrosis factor confers partial protection to Listeria infection
-
Torres D, Janot L, Quesniaux VFJ, Grivennikov SI, Maillet I, Sedgwick JD, et al. Membrane tumor necrosis factor confers partial protection to Listeria infection. Am J Pathol 2005; 167: 1677-87.
-
(2005)
Am J Pathol
, vol.167
, pp. 1677-1687
-
-
Torres, D.1
Janot, L.2
Quesniaux, V.F.J.3
Grivennikov, S.I.4
Maillet, I.5
Sedgwick, J.D.6
-
309
-
-
0025167803
-
Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis
-
Cominelli F, Nast CC, Clark BD, Schindler R, Llerena R, Eysselein VE, et al. Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. J Clin Invest 1990; 86: 972-80.
-
(1990)
J Clin Invest
, vol.86
, pp. 972-980
-
-
Cominelli, F.1
Nast, C.C.2
Clark, B.D.3
Schindler, R.4
Llerena, R.5
Eysselein, V.E.6
-
310
-
-
0026162985
-
Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant human interleukin-1 receptor antagonist
-
Henderson B, Thompson RC, Hardingham T, Lewthwaite J. Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant human interleukin-1 receptor antagonist. Cytokine 1991; 3: 246-9.
-
(1991)
Cytokine
, vol.3
, pp. 246-249
-
-
Henderson, B.1
Thompson, R.C.2
Hardingham, T.3
Lewthwaite, J.4
-
311
-
-
0025856061
-
Experimental autoimmune encephalomyelitis is exacerbated by IL-1 and suppressed by soluble IL-1 receptor
-
Jacobs CA, Baker PE, Roux ER, Picha KS, Toivola B, Waugh S, et al. Experimental autoimmune encephalomyelitis is exacerbated by IL-1 and suppressed by soluble IL-1 receptor. J Immunol 1991; 146: 2983-9.
-
(1991)
J Immunol
, vol.146
, pp. 2983-2989
-
-
Jacobs, C.A.1
Baker, P.E.2
Roux, E.R.3
Picha, K.S.4
Toivola, B.5
Waugh, S.6
-
313
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams RO, Feldmann M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. PNAS 1992; 89: 9784-8.
-
(1992)
PNAS
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
314
-
-
0027373406
-
Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response
-
Geiger T, Towbin H, Cosenti-Vargas A, Zingel O, Arnold J, Rordorf C, et al. Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response. Clin Exp Rheumatol 1993; 11: 515-22.
-
(1993)
Clin Exp Rheumatol
, vol.11
, pp. 515-522
-
-
Geiger, T.1
Towbin, H.2
Cosenti-Vargas, A.3
Zingel, O.4
Arnold, J.5
Rordorf, C.6
-
315
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim K, Li B, Winer J, Armanini M, Gillett N, Phillips H, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-4.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.6
-
316
-
-
0028066844
-
Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins
-
Baker D, Butler D, Scallon B, O'Neill J, Turk J, Feldmann M. Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur J Immunol 1994; 24: 2040-8.
-
(1994)
Eur J Immunol
, vol.24
, pp. 2040-2048
-
-
Baker, D.1
Butler, D.2
Scallon, B.3
O'Neill, J.4
Turk, J.5
Feldmann, M.6
-
317
-
-
0028966091
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
-
Leonard JP, Waldburger KE, Goldman SJ. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12. J Exp Med 1995; 181: 381-96.
-
(1995)
J Exp Med
, vol.181
, pp. 381-396
-
-
Leonard, J.P.1
Waldburger, K.E.2
Goldman, S.J.3
-
318
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss B, Kelsall BL, Stüber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995; 182: 1281-90.
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, B.2
Kelsall, B.L.3
Stüber, E.4
Strober, W.5
-
319
-
-
0029335074
-
Interleukin-4 is required for the induction of lung Th2 mucosal immunity
-
Coyle A, Le Gros G, Bertrand C, Tsuyuki S, Heusser C, Kopf M, et al. Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am J Respir Cell Mol Biol 1995; 13: 54-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 54-59
-
-
Coyle, A.1
Le Gros, G.2
Bertrand, C.3
Tsuyuki, S.4
Heusser, C.5
Kopf, M.6
-
320
-
-
0032536542
-
Interleukin 6 is required for the development of collagen-induced arthritis
-
Alonzi T, Fattori E, Lazzaro D, Costa P, Probert L, Kollias G, et al. Interleukin 6 is required for the development of collagen-induced arthritis. J Exp Med 1996; 187: 461-8.
-
(1996)
J Exp Med
, vol.187
, pp. 461-468
-
-
Alonzi, T.1
Fattori, E.2
Lazzaro, D.3
Costa, P.4
Probert, L.5
Kollias, G.6
-
321
-
-
0030040387
-
Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor
-
Renz H, Bradley K, Enssle K, Loader JE, Larsen GL, Gelfand EW. Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor;. Int Arch Allergy Immunol 1996; 109: 167-76.
-
(1996)
Int Arch Allergy Immunol
, vol.109
, pp. 167-176
-
-
Renz, H.1
Bradley, K.2
Enssle, K.3
Loader, J.E.4
Larsen, G.L.5
Gelfand, E.W.6
-
322
-
-
0031015257
-
Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
-
Kojouharoff G, Hans W, Obermeier F, Männel DN, Andus T, Schölmerich AJ, et al. Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol 1997; 107: 353-8.
-
(1997)
Clin Exp Immunol
, vol.107
, pp. 353-358
-
-
Kojouharoff, G.1
Hans, W.2
Obermeier, F.3
Männel, D.N.4
Andus, T.5
Schölmerich, A.J.6
-
323
-
-
0030947668
-
Treatment of ulcerative colitis in the cotton top tamarin using antibody to tumour necrosis factor alpha
-
Watkins PE, Warren BF, Stephens S, Ward P, Foulkes R. Treatment of ulcerative colitis in the cotton top tamarin using antibody to tumour necrosis factor alpha. Gut 1997; 40: 628-33.
-
(1997)
Gut
, vol.40
, pp. 628-633
-
-
Watkins, P.E.1
Warren, B.F.2
Stephens, S.3
Ward, P.4
Foulkes, R.5
-
324
-
-
0032211092
-
Antibodies against IL-12 prevent superantigeninduced and spontaneous relapses of experimental autoimmune encephalomyelitis
-
Constantinescu CS, Wysocka M, Hilliard B, Ventura ES, Lavi E, Trinchieri G, et al. Antibodies against IL-12 prevent superantigeninduced and spontaneous relapses of experimental autoimmune encephalomyelitis. J Immunol 1998; 161: 5097-104.
-
(1998)
J Immunol
, vol.161
, pp. 5097-5104
-
-
Constantinescu, C.S.1
Wysocka, M.2
Hilliard, B.3
Ventura, E.S.4
Lavi, E.5
Trinchieri, G.6
-
325
-
-
0031826252
-
Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice
-
Matthys P, Vermeire K, Mitera T, Heremans H, Huang S, Billiau A. Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice. Eur J Immunol 1998; 28: 2143-51.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2143-2151
-
-
Matthys, P.1
Vermeire, K.2
Mitera, T.3
Heremans, H.4
Huang, S.5
Billiau, A.6
-
326
-
-
8444245228
-
Effects of anticytokine therapy in a mouse model of chronic asthma
-
Kumar RK, Herbert C, Webb DC, Li L, Foster PS. Effects of anticytokine therapy in a mouse model of chronic asthma. Am J Respir Crit Care Med 2004; 170: 1043-8.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1043-1048
-
-
Kumar, R.K.1
Herbert, C.2
Webb, D.C.3
Li, L.4
Foster, P.S.5
-
327
-
-
1042267236
-
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction and bone erosion
-
Lubberts E, Koenders MI, Oppers-Walgreen B, Van den Bersselaar L, Coenen-de Roo CJJ, Joosten LAB, et al. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction and bone erosion. Arthritis Rheum 2004; 50: 650-9.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 650-659
-
-
Lubberts, E.1
Koenders, M.I.2
Oppers-Walgreen, B.3
Van den Bersselaar, L.4
Coenen-de Roo, C.J.J.5
Joosten, L.A.B.6
-
328
-
-
30944452780
-
Therapeutic efficacy of IL-17 neutralization murine experimental autoimmune encephalomyelitis
-
Hofstetter HH, Ibrahim SM, Koczan D, Kruse N, Weishaupt A, Toyka KV, et al. Therapeutic efficacy of IL-17 neutralization murine experimental autoimmune encephalomyelitis. Cell Immunol 2005; 237: 123-30.
-
(2005)
Cell Immunol
, vol.237
, pp. 123-130
-
-
Hofstetter, H.H.1
Ibrahim, S.M.2
Koczan, D.3
Kruse, N.4
Weishaupt, A.5
Toyka, K.V.6
-
329
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan TK, et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest 2006; 116: 1317-26.
-
(2006)
J Clin Invest
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.K.6
-
330
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie B, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med 2006; 203: 2473-93.
-
(2006)
J Exp Med
, vol.203
, pp. 2473-2493
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.6
-
331
-
-
36448931232
-
IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats
-
Yago T, Nanke Y, Kawamoto M, Furuya T, Kobashigawa T, Kamatani N, et al. IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats. Arthritis Res Ther 2007; 9: R96.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Yago, T.1
Nanke, Y.2
Kawamoto, M.3
Furuya, T.4
Kobashigawa, T.5
Kamatani, N.6
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