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Volumn 5, Issue 2, 2006, Pages 289-301

The safety of bevacizumab

Author keywords

Bevacizumab; Monoclonal antibody; Vascular endothelial growth factor (VEGF)

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; DOXORUBICIN; ERLOTINIB; ESTRAMUSTINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; OXALIPLATIN; PACLITAXEL; PEGINTERFERON; PLACEBO; THALIDOMIDE; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

EID: 33644895047     PISSN: 14740338     EISSN: None     Source Type: Journal    
DOI: 10.1517/14740338.5.2.289     Document Type: Review
Times cited : (29)

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    • Lack of effect of bevacizumab on wound healing/bleeding complications when given 28-60 days following primary cancer surgery
    • Abstract 3530
    • SCAPPATICCI F, FEHRENBACHER L, CARTWRIGHT T et al.: Lack of effect of bevacizumab on wound healing/bleeding complications when given 28-60 days following primary cancer surgery. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 3530.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Scappaticci, F.1    Fehrenbacher, L.2    Cartwright, T.3
  • 50
    • 21244472851 scopus 로고    scopus 로고
    • Wound healing/bleeding in metastatic colorectal cancer patients who undergo surgery during treatment with bevacizumab
    • Abstract 3702
    • HURWITZ H, FEHRENBACHER L, CARTWRIGHT T et al.: Wound healing/bleeding in metastatic colorectal cancer patients who undergo surgery during treatment with bevacizumab. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 3702.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Hurwitz, H.1    Fehrenbacher, L.2    Cartwright, T.3
  • 51
    • 33645521141 scopus 로고    scopus 로고
    • Safety of bevacizumab among patients receiving first-line chemotherapy for metastatic colorectal cancer: Preliminary results from a larger registry in the US
    • Abstract 3566
    • KOZLOFF M, COHN A, CHRISTIANSEN N et al.: Safety of bevacizumab among patients receiving first-line chemotherapy for metastatic colorectal cancer: Preliminary results from a larger registry in the US. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3566.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Kozloff, M.1    Cohn, A.2    Christiansen, N.3
  • 52
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized Phase II trial
    • KABBINAVAR FF, SCHULZ J, MCCLEOD M et al.: Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized Phase II trial. J. Clin. Oncol. (2005) 23:3697-3705.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 3697-3705
    • Kabbinavar, F.F.1    Schulz, J.2    McCleod, M.3
  • 53
    • 21244481589 scopus 로고    scopus 로고
    • High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group study E3200
    • Abstract 2
    • GIANTONIO BJ, CATALANO PJ, MEROPOL NJ et al.: High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group study E3200. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 2.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 54
    • 28344438302 scopus 로고    scopus 로고
    • Arterial thromboembolic events in a pooled analysis of 5 randomized, controlled trials of bevacizumab with chemotherapy
    • Abstract 3019
    • SKILLINGS JR, JOHNSON DH, MILLER K et al.: Arterial thromboembolic events in a pooled analysis of 5 randomized, controlled trials of bevacizumab with chemotherapy. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3019.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Skillings, J.R.1    Johnson, D.H.2    Miller, K.3
  • 55
    • 33645351051 scopus 로고    scopus 로고
    • Safety of low-dose aspirin in a pooled analysis of 3 randomized, controlled trials of bevacizumab with chemotherapy in patients with metastatic colorectal cancer
    • Abstract 3554
    • HAMBLETON J, SKILLINGS J, KABBINAVAR F et al.: Safety of low-dose aspirin in a pooled analysis of 3 randomized, controlled trials of bevacizumab with chemotherapy in patients with metastatic colorectal cancer. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3554.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Hambleton, J.1    Skillings, J.2    Kabbinavar, F.3
  • 56
    • 22744445443 scopus 로고    scopus 로고
    • Safety and efficacy of bevacizumab when added to oxaliplatin/fluoropyrimidine regimens as first-line treatment of metastatic colorectal cancer: TREE 1 & 2 studies
    • Abstract 3515
    • HOCHSTER HS, WELLES L, HART L et al.: Safety and efficacy of bevacizumab when added to oxaliplatin/fluoropyrimidine regimens as first-line treatment of metastatic colorectal cancer: TREE 1 & 2 studies. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3515.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Hochster, H.S.1    Welles, L.2    Hart, L.3
  • 57
    • 23844485828 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group study
    • Abstract 5009
    • BURGER RA, SILL M, MONK BJ et al.: Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group study. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 5009.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Burger, R.A.1    Sill, M.2    Monk, B.J.3
  • 58
    • 27644439175 scopus 로고    scopus 로고
    • Phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin's lymphoma: Southwest Oncology Group Study S0108
    • Abstract 6592
    • STOPECK AT, BELLAMY W, UNGER J et al.: Phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin's lymphoma: Southwest Oncology Group Study S0108. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 6592.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Stopeck, A.T.1    Bellamy, W.2    Unger, J.3
  • 59
    • 33644916333 scopus 로고    scopus 로고
    • Bevacizumab in hepatocellular carcinoma in patients without metastasis and without invasion of the portal vein
    • Abstract 4122
    • SCHWARTZ JD, SCHWARTZ M, LEHRER D et al.: Bevacizumab in hepatocellular carcinoma in patients without metastasis and without invasion of the portal vein. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 4122.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Schwartz, J.D.1    Schwartz, M.2    Lehrer, D.3
  • 60
    • 23844511435 scopus 로고    scopus 로고
    • Irinotecan, carboplatin, and radiotherapy followed by bevacizumab in the treatment of limited-stage small cell lung cancer: A Phase II trial of the Minnie Pearl Cancer Research Network
    • Abstract 7050
    • RAEFSKY EL, SPIGEL DR, GRECO FA et al.: Irinotecan, carboplatin, and radiotherapy followed by bevacizumab in the treatment of limited-stage small cell lung cancer: A Phase II trial of the Minnie Pearl Cancer Research Network. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 7050.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Raefsky, E.L.1    Spigel, D.R.2    Greco, F.A.3
  • 61
    • 0346880557 scopus 로고    scopus 로고
    • The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006
    • Abstract 1578
    • PICUS J, HALABI S, RINI B et al.: The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006. Proc. Am. Soc. Clin. Oncol. (2003) 22:Abstract 1578.
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22
    • Picus, J.1    Halabi, S.2    Rini, B.3
  • 62
    • 23844471164 scopus 로고    scopus 로고
    • A multicenter, double-blind, placebo-controlled randomized Phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma
    • Abstract 7019
    • KINDLER HL, KARRISON T, LU C et al.: A multicenter, double-blind, placebo-controlled randomized Phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 7019.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Kindler, H.L.1    Karrison, T.2    Lu, C.3
  • 63
    • 23844490388 scopus 로고    scopus 로고
    • A Phase II study of gemcitabine, oxaliplatin in combination with bevacizumab (GEMOX-B) in patients with hepatocellular carcinoma
    • Abstract 4120
    • ZHU AX, SAHANI D, NORDENZFONI A et al.: A Phase II study of gemcitabine, oxaliplatin in combination with bevacizumab (GEMOX-B) in patients with hepatocellular carcinoma. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 4120.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Zhu, A.X.1    Sahani, D.2    Nordenzfoni, A.3
  • 64
    • 28044441251 scopus 로고    scopus 로고
    • Improved progression free survival, and rapid, sustained decrease in tumor perfusion among patients with advanced carcinoid treated with bevacizumab
    • Abstract 4007
    • YAO JC, NG C, HOFF PM et al.: Improved progression free survival, and rapid, sustained decrease in tumor perfusion among patients with advanced carcinoid treated with bevacizumab. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 4007.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Yao, J.C.1    Ng, C.2    Hoff, P.M.3
  • 65
    • 23844471332 scopus 로고    scopus 로고
    • A multicenter Phase II study of irinotecan, cisplatin, and bevacizumab in patients with unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
    • Abstract 4025
    • SHAH MA, ILSON D, RAMANATHAN RK et al.: A multicenter Phase II study of irinotecan, cisplatin, and bevacizumab in patients with unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 4025.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Shah, M.A.1    Ilson, D.2    Ramanathan, R.K.3
  • 66
    • 27944483577 scopus 로고    scopus 로고
    • A Phase II study of oxaliplatin, capecitabine, and bevacizumab in the treatment of metastatic colorectal cancer
    • Abstract 3556
    • FERNANDO N, YU D, MORSE M et al.: A Phase II study of oxaliplatin, capecitabine, and bevacizumab in the treatment of metastatic colorectal cancer. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3556.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Fernando, N.1    Yu, D.2    Morse, M.3
  • 67
    • 33644974427 scopus 로고    scopus 로고
    • Phase I trial of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic adenocarcinoma
    • Abstract 4033
    • CRANE CH, ELLIS LM, ABBRUZZESE JL et al.: Phase I trial of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic adenocarcinoma. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 4033.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Crane, C.H.1    Ellis, L.M.2    Abbruzzese, J.L.3
  • 68
    • 22744435494 scopus 로고    scopus 로고
    • Phase I study of neoadjuvant bevacizumab, 5-fluorouracil, and radiation therapy followed by surgery for patients with primary rectal cancer
    • Abstract 3589
    • WILLETT CG, CHUNG D, SAHANI D et al.: Phase I study of neoadjuvant bevacizumab, 5-fluorouracil, and radiation therapy followed by surgery for patients with primary rectal cancer. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 3589.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Willett, C.G.1    Chung, D.2    Sahani, D.3
  • 69
    • 8344258509 scopus 로고    scopus 로고
    • Bevacizumab (B) plus gemcitabine (G) in patients (pts) with advanced pancreatic cancer (PC): Updated results of a multi-center Phase II trial
    • Abstract 4009
    • KINDLER HL, FRIBERG G, STADLER WM et al.: Bevacizumab (B) plus gemcitabine (G) in patients (pts) with advanced pancreatic cancer (PC): Updated results of a multi-center Phase II trial. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 4009.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Kindler, H.L.1    Friberg, G.2    Stadler, W.M.3
  • 70
    • 4444334483 scopus 로고    scopus 로고
    • Bevacizumab (BV) plus 5-FU/leucovorin (FU/LV) for advanced colorectal cancer (CRC) that progressed after standard chemotherapies: An NCI Treatment Referral Center trial (TRC-0301)
    • Abstract 3515
    • CHEN HX, MOONEY M, BORON M et al.: Bevacizumab (BV) plus 5-FU/leucovorin (FU/LV) for advanced colorectal cancer (CRC) that progressed after standard chemotherapies: An NCI Treatment Referral Center trial (TRC-0301). Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 3515.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Chen, H.X.1    Mooney, M.2    Boron, M.3
  • 71
    • 34250719424 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant docetaxel with or without bevacizumab in patients with locally advanced breast cancer
    • Abstract 727
    • OVERMOYER B, SILVERMAN P, LEEMING R et al.: Phase II trial of neoadjuvant docetaxel with or without bevacizumab in patients with locally advanced breast cancer. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 727.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Overmoyer, B.1    Silverman, P.2    Leeming, R.3
  • 73
    • 4744363900 scopus 로고    scopus 로고
    • Phase I/II trial evaluating the anti-VEGF Mab bevacizumab in combination with erlotinib, a HER1/EGFR-TK inhibitor, for patients with recurrent non-small cell lung cancer
    • Abstract 2000
    • SANDLER AB, BLUMENSCHEIN GR, HENDERSON T et al.: Phase I/II trial evaluating the anti-VEGF Mab bevacizumab in combination with erlotinib, a HER1/EGFR-TK inhibitor, for patients with recurrent non-small cell lung cancer. Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 2000.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Sandler, A.B.1    Blumenschein, G.R.2    Henderson, T.3
  • 74
    • 23844527898 scopus 로고    scopus 로고
    • A Phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck
    • Abstract 5504
    • VOKES EE, COHEN EE, MAUER AM et al.: A Phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 5504.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Vokes, E.E.1    Cohen, E.E.2    Mauer, A.M.3
  • 75
    • 27944456752 scopus 로고    scopus 로고
    • Bevacizumab and erlotinib in the treatment of patients with metastatic carcinoma of unknown primary site: A Sarah Cannon Research Institute Phase II trial
    • Abstract 3088
    • GRECO FA, SPIGEL DR, SHIPLEY DL et al.: Bevacizumab and erlotinib in the treatment of patients with metastatic carcinoma of unknown primary site: A Sarah Cannon Research Institute Phase II trial. Proc. Am. Soc. Clin. Oncol. (2005) 23:Abstract 3088.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Greco, F.A.1    Spigel, D.R.2    Shipley, D.L.3
  • 76
    • 7944228610 scopus 로고    scopus 로고
    • Phase II trial of erlotinib (OSI-774), an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, and bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF), in patients (pts) with metastatic breast cancer (MBC)
    • Abstract 2001
    • DICKLER M, RUGO H, CARAVELLI J et al.: Phase II trial of erlotinib (OSI-774), an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, and bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF), in patients (pts) with metastatic breast cancer (MBC). Proc. Am. Soc. Clin. Oncol. (2004) 23:Abstract 2001.
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Dickler, M.1    Rugo, H.2    Caravelli, J.3
  • 77
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    • Randomized Phase II trial of cetuximab/bevacizumab/irinotecan versus cetuximab/bevacizumab in irinotecan-refractory colorectal cancer
    • SALTZ LB, LENZ H, HOCHSTER H et al.: Randomized Phase II trial of cetuximab/bevacizumab/irinotecan versus cetuximab/bevacizumab in irinotecan-refractory colorectal cancer. Proc. Am. Soc. Clin. Oncol. (2005) 23:3508.
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23 , pp. 3508
    • Saltz, L.B.1    Lenz, H.2    Hochster, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.