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Volumn 126, Issue 1, 2009, Pages 63-73

Interleukin-15 stimulates macrophages to activate CD4+ T cells: A role in the pathogenesis of rheumatoid arthritis?

Author keywords

Cytokines; Macrophages; Rheumatoid arthritis; T cells

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; INTERLEUKIN 15; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 57449116787     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02878.x     Document Type: Article
Times cited : (48)

References (38)
  • 1
    • 0038644731 scopus 로고    scopus 로고
    • Differential STAT3, STAT5, and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15: Implications in the expression of functional molecules
    • Giron-Michel J, Caignard A, Fogli M et al. Differential STAT3, STAT5, and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15: implications in the expression of functional molecules. Blood 2003 102 : 109 17.
    • (2003) Blood , vol.102 , pp. 109-17
    • Giron-Michel, J.1    Caignard, A.2    Fogli, M.3
  • 2
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001 97 : 14 32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 3
    • 33645833872 scopus 로고    scopus 로고
    • The interleukin-15/interleukin-15 receptor system as a model for juxtacrine and reverse signaling
    • Bulfone-Paus S, Bulanova E, Budagian V, Paus R. The interleukin-15/ interleukin-15 receptor system as a model for juxtacrine and reverse signaling. Bioessays 2006 28 : 362 77.
    • (2006) Bioessays , vol.28 , pp. 362-77
    • Bulfone-Paus, S.1    Bulanova, E.2    Budagian, V.3    Paus, R.4
  • 5
    • 34247638873 scopus 로고    scopus 로고
    • The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for the immunotherapy of rheumatological diseases
    • Waldmann T. The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases. Arthritis Res 2002 4 (Suppl. 3 S161 7.
    • (2002) Arthritis Res , vol.4 , Issue.3
    • Waldmann, T.1
  • 6
    • 0030032290 scopus 로고    scopus 로고
    • Induction and regulation of IL-15 expression in murine macrophages
    • Doherty TM, Seder RA, Sher A. Induction and regulation of IL-15 expression in murine macrophages. J Immunol 1996 156 : 735 41.
    • (1996) J Immunol , vol.156 , pp. 735-41
    • Doherty, T.M.1    Seder, R.A.2    Sher, A.3
  • 7
    • 0031571801 scopus 로고    scopus 로고
    • IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: Evidence for differential receptor subunit utilization associated with stimulation or inhibition
    • Alleva DG, Kaser SB, Monroy MA, Fenton MJ, Beller DI. IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition. J Immunol 1997 159 : 2941 51.
    • (1997) J Immunol , vol.159 , pp. 2941-51
    • Alleva, D.G.1    Kaser, S.B.2    Monroy, M.A.3    Fenton, M.J.4    Beller, D.I.5
  • 8
    • 0031042456 scopus 로고    scopus 로고
    • Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis
    • McInnes IB, Leung BP, Sturrock RD, Field M, Liew FY. Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Nat Med 1997 3 : 189 95.
    • (1997) Nat Med , vol.3 , pp. 189-95
    • McInnes, I.B.1    Leung, B.P.2    Sturrock, R.D.3    Field, M.4    Liew, F.Y.5
  • 9
    • 0142156243 scopus 로고    scopus 로고
    • New strategies to control inflammatory synovitis: Interleukin 15 and beyond
    • McInnes IB, Gracie JA, Harnett M, Harnett W, Liew FY. New strategies to control inflammatory synovitis: interleukin 15 and beyond. Ann Rheum Dis 2003 62 (Suppl. 2 ii51 4.
    • (2003) Ann Rheum Dis , vol.62 , Issue.2
    • McInnes, I.B.1    Gracie, J.A.2    Harnett, M.3    Harnett, W.4    Liew, F.Y.5
  • 10
    • 0032103993 scopus 로고    scopus 로고
    • Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: A role for IL-15 in development of antigen-induced immunopathology
    • Ruchatz H, Leung BP, Wei XQ, McInnes IB, Liew FY. Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology. J Immunol 1998 160 : 5654 60.
    • (1998) J Immunol , vol.160 , pp. 5654-60
    • Ruchatz, H.1    Leung, B.P.2    Wei, X.Q.3    McInnes, I.B.4    Liew, F.Y.5
  • 11
    • 2942547418 scopus 로고    scopus 로고
    • - T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patients
    • - T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patients. Circulation 2004 109 : 2744 8.
    • (2004) Circulation , vol.109 , pp. 2744-8
    • Gerli, R.1    Schillaci, G.2    Giordano, A.3
  • 12
    • 0029958821 scopus 로고    scopus 로고
    • - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
    • - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J Clin Invest 1996 97 : 2027 37.
    • (1996) J Clin Invest , vol.97 , pp. 2027-37
    • Schmidt, D.1    Goronzy, J.J.2    Weyand, C.M.3
  • 13
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988 31 : 315 24.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-24
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3
  • 14
    • 0031715621 scopus 로고    scopus 로고
    • Validation of rheumatoid arthritis improvement criteria that include simplified joint counts
    • van Gestel AM, Haagsma CJ, van Riel PL. Validation of rheumatoid arthritis improvement criteria that include simplified joint counts. Arthritis Rheum 1998 41 : 1845 50.
    • (1998) Arthritis Rheum , vol.41 , pp. 1845-50
    • Van Gestel, A.M.1    Haagsma, C.J.2    Van Riel, P.L.3
  • 15
    • 0031775744 scopus 로고    scopus 로고
    • Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
    • Stumbles PA, Thomas JA, Pimm CL, Lee PT, Venaille TJ, Proksch S, Holt PG. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998 188 : 2019 31.
    • (1998) J Exp Med , vol.188 , pp. 2019-31
    • Stumbles, P.A.1    Thomas, J.A.2    Pimm, C.L.3    Lee, P.T.4    Venaille, T.J.5    Proksch, S.6    Holt, P.G.7
  • 16
    • 0036839553 scopus 로고    scopus 로고
    • Bone destruction in arthritis
    • Gravallese EM. Bone destruction in arthritis. Ann Rheum Dis 2002 61 (Suppl. 2 ii84 6.
    • (2002) Ann Rheum Dis , vol.61 , Issue.2
    • Gravallese, E.M.1
  • 18
    • 0345257344 scopus 로고    scopus 로고
    • Interleukin-21 inhibits dendritic cell activation and maturation
    • Brandt K, Bulfone-Paus S, Foster DC, Rückert R. Interleukin-21 inhibits dendritic cell activation and maturation. Blood 2003 102 : 4090 8.
    • (2003) Blood , vol.102 , pp. 4090-8
    • Brandt, K.1    Bulfone-Paus, S.2    Foster, D.C.3    Rückert, R.4
  • 19
    • 1542283726 scopus 로고    scopus 로고
    • End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6
    • Klausen P, Bjerregaard MD, Borregaard N, Cowland JB. End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6. J Leukoc Biol 2004 75 : 569 78.
    • (2004) J Leukoc Biol , vol.75 , pp. 569-78
    • Klausen, P.1    Bjerregaard, M.D.2    Borregaard, N.3    Cowland, J.B.4
  • 20
    • 0033166302 scopus 로고    scopus 로고
    • Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
    • Xaus J, Cardo M, Valledor AF, Soler C, Lloberas J, Celada A. Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity 1999 11 : 103 13.
    • (1999) Immunity , vol.11 , pp. 103-13
    • Xaus, J.1    Cardo, M.2    Valledor, A.F.3    Soler, C.4    Lloberas, J.5    Celada, A.6
  • 21
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo M, Hanada T, Yoshimura A. Suppressors of cytokine signaling and immunity. Nat Immunol 2003 4 : 1169 76.
    • (2003) Nat Immunol , vol.4 , pp. 1169-76
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 22
    • 0037352702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages
    • Ojaniemi M, Glumoff V, Harju K, Liljeroos M, Vuori K, Hallman M. Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages. Eur J Immunol 2003 33 : 597 605.
    • (2003) Eur J Immunol , vol.33 , pp. 597-605
    • Ojaniemi, M.1    Glumoff, V.2    Harju, K.3    Liljeroos, M.4    Vuori, K.5    Hallman, M.6
  • 23
    • 0031711479 scopus 로고    scopus 로고
    • IL-15-IgG2b fusion protein accelerates and enhances a Th2 but not a Th1 immune response in vivo, while IL-2-IgG2b fusion protein inhibits both
    • Rückert R, Herz U, Paus R, Ungureanu D, Pohl T, Renz H, Bulfone-Paus S. IL-15-IgG2b fusion protein accelerates and enhances a Th2 but not a Th1 immune response in vivo, while IL-2-IgG2b fusion protein inhibits both. Eur J Immunol 1998 28 : 3312 20.
    • (1998) Eur J Immunol , vol.28 , pp. 3312-20
    • Rückert, R.1    Herz, U.2    Paus, R.3    Ungureanu, D.4    Pohl, T.5    Renz, H.6    Bulfone-Paus, S.7
  • 24
    • 0033557566 scopus 로고    scopus 로고
    • CD8 T-cell infiltration in extravascular tissues of patients with human immunodeficiency virus infection. Interleukin-15 upmodulates costimulatory pathways involved in the antigen-presenting cells-T-cell interaction
    • Agostini C, Zambello R, Facco M et al. CD8 T-cell infiltration in extravascular tissues of patients with human immunodeficiency virus infection. Interleukin-15 upmodulates costimulatory pathways involved in the antigen-presenting cells-T-cell interaction. Blood 1999 93 : 1277 86.
    • (1999) Blood , vol.93 , pp. 1277-86
    • Agostini, C.1    Zambello, R.2    Facco, M.3
  • 25
    • 3142732829 scopus 로고    scopus 로고
    • IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: Effect of methotrexate
    • Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez dA, Martin-Mola E. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J Immunol 2004 173 : 1463 76.
    • (2004) J Immunol , vol.173 , pp. 1463-76
    • Miranda-Carus, M.E.1    Balsa, A.2    Benito-Miguel, M.3    Da, P.4    Martin-Mola, E.5
  • 26
    • 0036826914 scopus 로고    scopus 로고
    • IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells
    • Dubois S, Mariner J, Waldmann TA, Tagaya Y. IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells. Immunity 2002 17 : 537 47.
    • (2002) Immunity , vol.17 , pp. 537-47
    • Dubois, S.1    Mariner, J.2    Waldmann, T.A.3    Tagaya, Y.4
  • 27
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy MK, Glaccum M, Brown SN et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000 191 : 771 80.
    • (2000) J Exp Med , vol.191 , pp. 771-80
    • Kennedy, M.K.1    Glaccum, M.2    Brown, S.N.3
  • 28
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, Boone DL, Chai S, Swain RE, Dassopoulos T, Trettin S, Ma A. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998 9 : 669 76.
    • (1998) Immunity , vol.9 , pp. 669-76
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3    Swain, R.E.4    Dassopoulos, T.5    Trettin, S.6    Ma, A.7
  • 29
    • 0036177482 scopus 로고    scopus 로고
    • + T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro
    • + T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro. Eur J Immunol 2002 32 : 341 7.
    • (2002) Eur J Immunol , vol.32 , pp. 341-7
    • Niedbala, W.1    Wei, X.2    Liew, F.Y.3
  • 30
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K, Ishida N, Shirane M et al. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996 85 : 707 20.
    • (1996) Cell , vol.85 , pp. 707-20
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3
  • 31
    • 0028172867 scopus 로고
    • Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin
    • Nourse J, Firpo E, Flanagan WM et al. Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 1994 372 : 570 3.
    • (1994) Nature , vol.372 , pp. 570-3
    • Nourse, J.1    Firpo, E.2    Flanagan, W.M.3
  • 34
    • 15444343191 scopus 로고    scopus 로고
    • Mouse macrophage development in the absence of the common gamma chain: Defining receptor complexes responsible for IL-4 and IL-13 signaling
    • Andersson A, Grunewald SM, Duschl A, Fischer A, DiSanto JP. Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling. Eur J Immunol 1997 27 : 1762 8.
    • (1997) Eur J Immunol , vol.27 , pp. 1762-8
    • Andersson, A.1    Grunewald, S.M.2    Duschl, A.3    Fischer, A.4    Disanto, J.P.5
  • 35
    • 0032522965 scopus 로고    scopus 로고
    • Abnormal myelocytic cell development in interleukin-2 (IL-2) -deficient mice: Evidence for the involvement of IL-2 in myelopoiesis
    • Reya T, Contractor NV, Couzens MS, Wasik MA, Emerson SG, Carding SR. Abnormal myelocytic cell development in interleukin-2 (IL-2) -deficient mice: evidence for the involvement of IL-2 in myelopoiesis. Blood 1998 91 : 2935 47.
    • (1998) Blood , vol.91 , pp. 2935-47
    • Reya, T.1    Contractor, N.V.2    Couzens, M.S.3    Wasik, M.A.4    Emerson, S.G.5    Carding, S.R.6
  • 36
    • 0025730561 scopus 로고
    • Influence of interleukin-2 on the differentiation of macrophages
    • Lohmann-Matthes ML, Emmendoerffer A, Hao L. Influence of interleukin-2 on the differentiation of macrophages. Pathobiology 1991 59 : 117 21.
    • (1991) Pathobiology , vol.59 , pp. 117-21
    • Lohmann-Matthes, M.L.1    Emmendoerffer, A.2    Hao, L.3
  • 37
    • 0036839148 scopus 로고    scopus 로고
    • Role of interleukin 15 and interleukin 18 in inflammatory response
    • Liew FY, McInnes IB. Role of interleukin 15 and interleukin 18 in inflammatory response. Ann Rheum Dis 2002 61 (Suppl. 2 ii 100 2.
    • (2002) Ann Rheum Dis , vol.61 , Issue.2
    • Liew, F.Y.1    McInnes, I.B.2
  • 38
    • 33646353397 scopus 로고    scopus 로고
    • Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes
    • Miranda-Carus ME, Benito-Miguel M, Balsa A, Cobo-Ibanez T, Perez de Ayala C, Pascual-Salcedo D, Martin-Mola E. Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes. Arthritis Rheum 2006 54 : 1151 64.
    • (2006) Arthritis Rheum , vol.54 , pp. 1151-64
    • Miranda-Carus, M.E.1    Benito-Miguel, M.2    Balsa, A.3    Cobo-Ibanez, T.4    Perez De Ayala, C.5    Pascual-Salcedo, D.6    Martin-Mola, E.7


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