메뉴 건너뛰기




Volumn 170, Issue 6, 2004, Pages 601-605

"Refractory" eosinophilic airway inflammation in severe asthma: Effect of parenteral corticosteroids

Author keywords

Asthma; Eosinophilia; Glucocorticoids; Phenotype; Severity of illness index; Sputum

Indexed keywords

ANTIASTHMATIC AGENT; BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; IMMUNOMODULATING AGENT; KENACORT A40; NITRIC OXIDE; PREDNISONE; SALBUTAMOL; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE;

EID: 4444221246     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200404-440OC     Document Type: Article
Times cited : (212)

References (38)
  • 1
    • 0043075805 scopus 로고    scopus 로고
    • Heterogeneity in the pathology and treatment of asthma
    • Peters SP. Heterogeneity in the pathology and treatment of asthma. Am J Med 2003;115(Suppl 3A):49S-54S.
    • (2003) Am J Med , vol.115 , Issue.SUPPL. 3A
    • Peters, S.P.1
  • 3
    • 0036310908 scopus 로고    scopus 로고
    • Non-eosinophilic asthma: Importance and possible mechanisms
    • Douwes J, Gibson P, Pekkanen J, Pearce N. Non-eosinophilic asthma: importance and possible mechanisms. Thorax 2002;57:643-648.
    • (2002) Thorax , vol.57 , pp. 643-648
    • Douwes, J.1    Gibson, P.2    Pekkanen, J.3    Pearce, N.4
  • 4
    • 0036795111 scopus 로고    scopus 로고
    • Analysis of induced sputum in adults with asthma: Identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
    • Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID. Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 2002;57:875-879.
    • (2002) Thorax , vol.57 , pp. 875-879
    • Green, R.H.1    Brightling, C.E.2    Woltmann, G.3    Parker, D.4    Wardlaw, A.J.5    Pavord, I.D.6
  • 6
    • 0034942124 scopus 로고    scopus 로고
    • Heterogeneity of airway inflammation in persistent asthma: Evidence of neutrophilic inflammation and increased sputum interleukin-8
    • Gibson PG, Simpson JL, Saltos N. Heterogeneity of airway inflammation in persistent asthma: evidence of neutrophilic inflammation and increased sputum interleukin-8. Chest 2001;119:1329-1336.
    • (2001) Chest , vol.119 , pp. 1329-1336
    • Gibson, P.G.1    Simpson, J.L.2    Saltos, N.3
  • 7
    • 10744231300 scopus 로고    scopus 로고
    • The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma
    • European Network for Understanding Mechanisms of Severe Asthma. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. Eur Respir J 2003;22:470-477.
    • (2003) Eur Respir J , vol.22 , pp. 470-477
  • 9
    • 0030859389 scopus 로고    scopus 로고
    • Bronchoscopic evaluation of severe asthma: Persistent inflammation associated with high dose glucocorticoids
    • Wenzel SE, Szefler SJ, Leung DY, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma: persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 1997;156:737-743.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 737-743
    • Wenzel, S.E.1    Szefler, S.J.2    Leung, D.Y.3    Sloan, S.I.4    Rex, M.D.5    Martin, R.J.6
  • 10
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel SE, Schwartz LB, Langmack EL, Halliday JL, Trudeau JB, Gibbs RL, Chu HW. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999;160:1001-1008.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3    Halliday, J.L.4    Trudeau, J.B.5    Gibbs, R.L.6    Chu, H.W.7
  • 12
    • 0346041503 scopus 로고    scopus 로고
    • Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation
    • Miranda C, Busacker A, Balzar S, Trudeau J, Wenzel SE. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004;113:101-108.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 101-108
    • Miranda, C.1    Busacker, A.2    Balzar, S.3    Trudeau, J.4    Wenzel, S.E.5
  • 14
    • 0030010572 scopus 로고    scopus 로고
    • Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids
    • Sont JK, Han J, van Krieken JM, Evertse CE, Hooijer R, Willems LN, Sterk PJ. Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 1996;51:496-502.
    • (1996) Thorax , vol.51 , pp. 496-502
    • Sont, J.K.1    Han, J.2    Van Krieken, J.M.3    Evertse, C.E.4    Hooijer, R.5    Willems, L.N.6    Sterk, P.J.7
  • 16
    • 0036227346 scopus 로고    scopus 로고
    • Bronchial inflammation in corticosteroid-sensitive and corticosteroid-resistant asthma at baseline and on oral corticosteroid treatment
    • Chakir J, Hamid Q, Bosse M, Boulet LP, Laviolette M. Bronchial inflammation in corticosteroid-sensitive and corticosteroid-resistant asthma at baseline and on oral corticosteroid treatment. Clin Exp Allergy 2002;32:578-582.
    • (2002) Clin Exp Allergy , vol.32 , pp. 578-582
    • Chakir, J.1    Hamid, Q.2    Bosse, M.3    Boulet, L.P.4    Laviolette, M.5
  • 22
    • 0033025989 scopus 로고    scopus 로고
    • Difficult/therapy-resistant asthma: The need for an integrated approach to define clinical pheno-types, evaluate risk factors, understand pathophysiology and find novel therapies: ERS Task Force on Difficult/Therapy- Resistant Asthma: European Respiratory Society
    • Chung KF, Godard P, Adelroth E, Ayres J, Barnes N, Barnes P, Bel E, Burney P, Chanez P, Connett G, et al. Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical pheno-types, evaluate risk factors, understand pathophysiology and find novel therapies: ERS Task Force on Difficult/Therapy-Resistant Asthma: European Respiratory Society. Eur Respir J 1999;13:1198-1208.
    • (1999) Eur Respir J , vol.13 , pp. 1198-1208
    • Chung, K.F.1    Godard, P.2    Adelroth, E.3    Ayres, J.4    Barnes, N.5    Barnes, P.6    Bel, E.7    Burney, P.8    Chanez, P.9    Connett, G.10
  • 24
    • 0027564322 scopus 로고
    • Lung volumes and forced ventilatory flows: Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal: Official Statement of the European Respiratory Society
    • Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows: Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal: Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:5-40.
    • (1993) Eur Respir J Suppl , vol.16 , pp. 5-40
    • Quanjer, P.H.1    Tammeling, G.J.2    Cotes, J.E.3    Pedersen, O.F.4    Peslin, R.5    Yernault, J.C.6
  • 25
    • 2642654231 scopus 로고    scopus 로고
    • Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects
    • de Gouw HW, Grunberg K, Schot R, Kroes AC, Dick EC, Sterk PJ. Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. Eur Respir J 1998;11:126-132.
    • (1998) Eur Respir J , vol.11 , pp. 126-132
    • Gouw, H.W.1    Grunberg, K.2    Schot, R.3    Kroes, A.C.4    Dick, E.C.5    Sterk, P.J.6
  • 27
    • 0024520896 scopus 로고
    • A comparison of the visual analogue scale and modified Borg scale for the measurement of dyspnoea during exercise
    • Wilson RC, Jones PW. A comparison of the visual analogue scale and modified Borg scale for the measurement of dyspnoea during exercise. Clin Sci 1989;76:277-282.
    • (1989) Clin Sci , vol.76 , pp. 277-282
    • Wilson, R.C.1    Jones, P.W.2
  • 29
    • 0031735358 scopus 로고    scopus 로고
    • Genetic factors in asthma severity
    • Hall IP. Genetic factors in asthma severity. Clin Exp Allergy 1998;28:16-20.
    • (1998) Clin Exp Allergy , vol.28 , pp. 16-20
    • Hall, I.P.1
  • 30
    • 0037248247 scopus 로고    scopus 로고
    • Update on glucocorticoid action and resistance
    • Leung DY, Bloom JW. Update on glucocorticoid action and resistance. J Allergy Clin Immunol 2003;111:3-22.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 3-22
    • Leung, D.Y.1    Bloom, J.W.2
  • 31
    • 0141497509 scopus 로고    scopus 로고
    • How do corticosteroids work in asthma?
    • Barnes PJ, Adcock IM. How do corticosteroids work in asthma? Ann Intern Med 2003;139:359-370.
    • (2003) Ann Intern Med , vol.139 , pp. 359-370
    • Barnes, P.J.1    Adcock, I.M.2
  • 33
    • 0032938331 scopus 로고    scopus 로고
    • Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment: The AMPUL Study Group
    • Sont JK, Willems LN, Bel EH, van Krieken JH, Vandenbroucke JP, Sterk PJ. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment: the AMPUL Study Group. Am J Respir Crit Care Med 1999;159:1043-1051.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1043-1051
    • Sont, J.K.1    Willems, L.N.2    Bel, E.H.3    Van Krieken, J.H.4    Vandenbroucke, J.P.5    Sterk, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.