-
1
-
-
0035069606
-
The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation Patient-Membership Survey
-
G Krueger J Koo M Lebwohl A Menter RS Stern T Rolstad The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation Patient-Membership Survey Arch Dermatol 137 2001 280 284
-
(2001)
Arch Dermatol
, vol.137
, pp. 280-284
-
-
Krueger, G1
Koo, J2
Lebwohl, M3
Menter, A4
Stern, RS5
Rolstad, T6
-
3
-
-
32644449372
-
What have we learned in dermatology from the biologic therapies?
-
BJ Nickoloff SR Stevens What have we learned in dermatology from the biologic therapies? J Am Acad Dermatol 54 3 suppl 2 2006 S143 S151
-
(2006)
J Am Acad Dermatol
, vol.54
, Issue.3 suppl 2
, pp. S143-S151
-
-
Nickoloff, BJ1
Stevens, SR2
-
4
-
-
4544388284
-
Biological therapies in the systemic management of psoriasis
-
W Sterry J Barker W-H Boehncke Biological therapies in the systemic management of psoriasis Br J Dermatol 151 2004 3 17
-
(2004)
Br J Dermatol
, vol.151
, pp. 3-17
-
-
Sterry, W1
Barker, J2
Boehncke, W-H3
-
5
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
M Cargill SJ Schrodi M Chang A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes Am J Hum Genet 80 2007 273 290
-
(2007)
Am J Hum Genet
, vol.80
, pp. 273-290
-
-
Cargill, M1
Schrodi, SJ2
Chang, M3
-
6
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
RH Duerr KD Taylor SR Brant A genome-wide association study identifies IL23R as an inflammatory bowel disease gene Science 314 2006 1461 1463
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, RH1
Taylor, KD2
Brant, SR3
-
7
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
F Capon P Di Meglio J Szaub Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis Hum Genet 122 2007 201 206
-
(2007)
Hum Genet
, vol.122
, pp. 201-206
-
-
Capon, F1
Di Meglio, P2
Szaub, J3
-
8
-
-
31144441631
-
In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin
-
G Piskin RMR Sylva-Steenland JD Bos MBM Teunissen In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin J Immunol 176 2006 1908 1915
-
(2006)
J Immunol
, vol.176
, pp. 1908-1915
-
-
Piskin, G1
Sylva-Steenland, RMR2
Bos, JD3
Teunissen, MBM4
-
9
-
-
0033564323
-
IL-12, independently of IFN-γ, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder
-
K Hong A Chu BR Ludviksson EL Berg RO Ehrhardt IL-12, independently of IFN-γ, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder J Immunol 162 1999 7480 7491
-
(1999)
J Immunol
, vol.162
, pp. 7480-7491
-
-
Hong, K1
Chu, A2
Ludviksson, BR3
Berg, EL4
Ehrhardt, RO5
-
10
-
-
36049052516
-
Interleukin-12, interleukin-23, and psoriasis: current prospects
-
DC Torti SR Feldman Interleukin-12, interleukin-23, and psoriasis: current prospects J Am Acad Dermatol 57 2007 1059 1068
-
(2007)
J Am Acad Dermatol
, vol.57
, pp. 1059-1068
-
-
Torti, DC1
Feldman, SR2
-
11
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
GG Krueger RG Langley C Leonardi A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis N Engl J Med 356 2007 580 592
-
(2007)
N Engl J Med
, vol.356
, pp. 580-592
-
-
Krueger, GG1
Langley, RG2
Leonardi, C3
-
12
-
-
39649108216
-
Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial
-
A Kimball KB Gordon RG Langley Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial Arch Dermatol 144 2008 200 207
-
(2008)
Arch Dermatol
, vol.144
, pp. 200-207
-
-
Kimball, A1
Gordon, KB2
Langley, RG3
-
13
-
-
43449111187
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
KA Papp RG Langley M Lebwohl Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2) Lancet 371 2008 1675 1684
-
(2008)
Lancet
, vol.371
, pp. 1675-1684
-
-
Papp, KA1
Langley, RG2
Lebwohl, M3
-
14
-
-
0016799829
-
Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial
-
S Pocock R Simon Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial Biometrics 31 1975 103 115
-
(1975)
Biometrics
, vol.31
, pp. 103-115
-
-
Pocock, S1
Simon, R2
-
15
-
-
0018099294
-
Severe psoriasis—oral therapy with a new retinoid
-
T Fredriksson U Pettersson Severe psoriasis—oral therapy with a new retinoid Dermatologica 157 1978 238 244
-
(1978)
Dermatologica
, vol.157
, pp. 238-244
-
-
Fredriksson, T1
Pettersson, U2
-
16
-
-
0028332995
-
Dermatology life quality index (DLQI)—a simple practical measure for routine clinical use
-
AY Finlay GK Khan Dermatology life quality index (DLQI)—a simple practical measure for routine clinical use Clin Exp Dermatol 19 1994 210 216
-
(1994)
Clin Exp Dermatol
, vol.19
, pp. 210-216
-
-
Finlay, AY1
Khan, GK2
-
19
-
-
40049103519
-
IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice
-
E Smith A Zarbock MA Stark IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice J Immunol 179 2007 8274 8279
-
(2007)
J Immunol
, vol.179
, pp. 8274-8279
-
-
Smith, E1
Zarbock, A2
Stark, MA3
-
20
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
G Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat Rev Immunol 3 2003 133 146
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G1
-
21
-
-
0036145337
-
The immunologic basis for the treatment of psoriasis with new biologic agents
-
JG Krueger The immunologic basis for the treatment of psoriasis with new biologic agents J Am Acad Dermatol 46 2002 1 23
-
(2002)
J Am Acad Dermatol
, vol.46
, pp. 1-23
-
-
Krueger, JG1
-
22
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
NJ Wilson K Boniface JR Chan Development, cytokine profile and function of human interleukin 17-producing helper T cells Nat Immunol 8 2007 950 957
-
(2007)
Nat Immunol
, vol.8
, pp. 950-957
-
-
Wilson, NJ1
Boniface, K2
Chan, JR3
-
23
-
-
0029848134
-
A proinflammatory activity of interleukin 8 in human skin: expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes
-
D Bruch-Gerharz K Fehsel C Suschek G Michel T Ruzicka V Kolb-Bachofen A proinflammatory activity of interleukin 8 in human skin: expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes J Exp Med 184 1996 2007 2012
-
(1996)
J Exp Med
, vol.184
, pp. 2007-2012
-
-
Bruch-Gerharz, D1
Fehsel, K2
Suschek, C3
Michel, G4
Ruzicka, T5
Kolb-Bachofen, V6
-
24
-
-
33847757147
-
Cracking the cytokine code in psoriasis
-
BJ Nickoloff Cracking the cytokine code in psoriasis Nat Med 13 2007 242 244
-
(2007)
Nat Med
, vol.13
, pp. 242-244
-
-
Nickoloff, BJ1
-
25
-
-
14744284737
-
IL-23 upregulates IL-10 and induces IL-17 synthesis by polyclonally activated naïve T cells in human
-
S Vanden Eijnden S Goriely D De Wit F Willems M Goldman IL-23 upregulates IL-10 and induces IL-17 synthesis by polyclonally activated naïve T cells in human Eur J Immunol 35 2005 469 475
-
(2005)
Eur J Immunol
, vol.35
, pp. 469-475
-
-
Vanden Eijnden, S1
Goriely, S2
De Wit, D3
Willems, F4
Goldman, M5
-
26
-
-
33846906224
-
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Y Zheng DM Danilenko P Valdez Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Nature 445 2007 648 651
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y1
Danilenko, DM2
Valdez, P3
-
27
-
-
9744229972
-
The IL-12 family member p40 chain as a master switch and novel therapeutic target in psoriasis
-
FO Nestle C Conrad The IL-12 family member p40 chain as a master switch and novel therapeutic target in psoriasis J Invest Dermatol 123 2004 XIV XV
-
(2004)
J Invest Dermatol
, vol.123
, pp. XIV-XV
-
-
Nestle, FO1
Conrad, C2
-
28
-
-
2542445474
-
A 50% reduction in the psoriasis area and severity index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis
-
CS Carlin SR Feldman JG Krueger A Menter GG Krueger A 50% reduction in the psoriasis area and severity index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis J Am Acad Dermatol 50 2004 859 866
-
(2004)
J Am Acad Dermatol
, vol.50
, pp. 859-866
-
-
Carlin, CS1
Feldman, SR2
Krueger, JG3
Menter, A4
Krueger, GG5
-
31
-
-
0038759100
-
The role of interleukin-12 in human infectious diseases: only a faint signature
-
C Fieschi JL Casanova The role of interleukin-12 in human infectious diseases: only a faint signature Eur J Immunol 33 2003 1461 1464
-
(2003)
Eur J Immunol
, vol.33
, pp. 1461-1464
-
-
Fieschi, C1
Casanova, JL2
-
32
-
-
0032577295
-
Severe mycobacterial and salmonella infections in interleukin-12 receptor-deficient patients
-
R de Jong F Altare IA Haagen Severe mycobacterial and salmonella infections in interleukin-12 receptor-deficient patients Science 280 1998 1435 1438
-
(1998)
Science
, vol.280
, pp. 1435-1438
-
-
de Jong, R1
Altare, F2
Haagen, IA3
-
33
-
-
33751428718
-
The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder
-
S Philipp K Wolk S Kreutzer The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder Expert Opin Ther Targets 10 2006 817 831
-
(2006)
Expert Opin Ther Targets
, vol.10
, pp. 817-831
-
-
Philipp, S1
Wolk, K2
Kreutzer, S3
-
34
-
-
1842555395
-
Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
-
RS Stern T Nijsten SR Feldman DJ Margolis T Rolstad Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction J Invest Dermatol Symp Proc 9 2004 136 139
-
(2004)
J Invest Dermatol Symp Proc
, vol.9
, pp. 136-139
-
-
Stern, RS1
Nijsten, T2
Feldman, SR3
Margolis, DJ4
Rolstad, T5
|