Role of infliximab in the treatment of early rheumatoid arthritis

Clinical and Experimental Rheumatology

Volumn 21, Issue 5 SUPPL. 31, 2003, Pages

  Keystone, Edward C ^a,c   Haraoui, Boulos ^b   Bykerk, Vivian P ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Biologic therapies; Early; Infliximab; Rheumatoid arthritis

Indexed keywords

CORTICOSTEROID; INFLIXIMAB; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; CLINICAL TRIAL; DATA ANALYSIS; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG WITHDRAWAL; FOOT RADIOGRAPHY; HAND RADIOGRAPHY; HUMAN; JOINT DESTRUCTION; MAINTENANCE DRUG DOSE; PRIORITY JOURNAL; REMISSION; RHEUMATOID ARTHRITIS; SYMPTOMATOLOGY;

EID: 0142124920     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. MAINI R, St CLAIR, EW, BREEDVELD F et al. for the Attract Study Group: Infliximab (chimeric anti-tumor necrosis factor α monoclonal antibody versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate; a randomized phase III trial. Lancet 1999; 354: 1932-9.
2. EMERY P, MAINI R, BREEDVELD F et al.: Infliximab plus methotrexate inhibits structural damage, reduces sign and symptoms and improves disability in patients with active early rheumatoid arthritis. Ann Rheum Dis 2001; 60 (Suppl.): Abstract No. Op0087, ppt 67.
3. TAYLOR PC, SEVEN S, GEIBER J et al.: Infliximab attenuates joint destruction in early RA patients with ultrasonographic markers of poor prognosis. Arthritis Rheum 2002; 9 (Suppl.): S334.
4. CONAGHAN PG, QUINN MA, O'CONNOR P, WAKEFIED RJ, KARIM A, EMERY P: Can very high-dose anti-tumor necrosis factor blockade at onset of rheumatoid arthritis produce long-term remission ? Arthritis Rheum 2002; 7: 1971-2.
5. QUINN MA, CONOGHAN PG, GREENSTEIN A, KARIM Z, BROWN C, EMERY P: Sustained response in early poor prognosis RA after withdrawal of infliximab therapy. Arthritis Rheum 2002; 46 (Suppl. 9): LB03.