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Volumn 19, Issue 5, 2003, Pages 679-688

Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; AUTOANTIBODY; DNA VACCINE; EPITOPE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 0345358581     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(03)00291-7     Document Type: Article
Times cited : (68)

References (41)
  • 1
    • 0028172557 scopus 로고
    • Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids
    • Arend W.P., Malyak M., Smith M.F. Jr., Whisenand T.D., Slack J.L., Sims J.E., Giri J.G., Dower S.K. Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids. J. Immunol. 153:1994;4766-4774.
    • (1994) J. Immunol. , vol.153 , pp. 4766-4774
    • Arend, W.P.1    Malyak, M.2    Smith Jr., M.F.3    Whisenand, T.D.4    Slack, J.L.5    Sims, J.E.6    Giri, J.G.7    Dower, S.K.8
  • 2
    • 0026681182 scopus 로고
    • Anti-arthritic effects demonstrated by an interleukin-2 receptor-targeted cytotoxin (DAB486IL-2) in rat adjuvant arthritis
    • Bacha P., Forte S.E., Perper S.J., Trentham D.E., Nichols J.C. Anti-arthritic effects demonstrated by an interleukin-2 receptor-targeted cytotoxin (DAB486IL-2) in rat adjuvant arthritis. Eur. J. Immunol. 22:1992;1673-1679.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1673-1679
    • Bacha, P.1    Forte, S.E.2    Perper, S.J.3    Trentham, D.E.4    Nichols, J.C.5
  • 3
    • 0036796777 scopus 로고    scopus 로고
    • Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: A phase II double-blinded, randomized, dose-escalating trial
    • Choy E.H., Hazleman B., Smith M., Moss K., Lisi L., Scott D.G., Patel J., Sopwith M., Isenberg D.A. Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis. a phase II double-blinded, randomized, dose-escalating trial Rheumatology (Oxford). 41:2002;1133-1137.
    • (2002) Rheumatology (Oxford) , vol.41 , pp. 1133-1137
    • Choy, E.H.1    Hazleman, B.2    Smith, M.3    Moss, K.4    Lisi, L.5    Scott, D.G.6    Patel, J.7    Sopwith, M.8    Isenberg, D.A.9
  • 5
    • 0030996312 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis
    • Feldmann M., Elliott M.J., Woody J.N., Maini R.N. Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis. Adv. Immunol. 64:1997;283-350.
    • (1997) Adv. Immunol. , vol.64 , pp. 283-350
    • Feldmann, M.1    Elliott, M.J.2    Woody, J.N.3    Maini, R.N.4
  • 7
    • 0029670540 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 immunity in neonatal mice
    • Forsthuber T., Yip H.C., Lehmann P.V. Induction of TH1 and TH2 immunity in neonatal mice. Science. 271:1996;1728-1730.
    • (1996) Science , vol.271 , pp. 1728-1730
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 8
    • 0022635695 scopus 로고
    • Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation
    • Gammon G., Don K., Shastri N., Oki A., Wilbur S., Sercarz E.E. Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation. Nature. 309:1986;413-415.
    • (1986) Nature , vol.309 , pp. 413-415
    • Gammon, G.1    Don, K.2    Shastri, N.3    Oki, A.4    Wilbur, S.5    Sercarz, E.E.6
  • 9
    • 0034897403 scopus 로고    scopus 로고
    • Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway
    • Garren H., Ruiz P.J., Watkins T.A., Fontoura P., Nguyen L.T., Estline E.R., Hirschberg D.L., Steinman L. Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway. Immunity. 15:2001;15-22.
    • (2001) Immunity , vol.15 , pp. 15-22
    • Garren, H.1    Ruiz, P.J.2    Watkins, T.A.3    Fontoura, P.4    Nguyen, L.T.5    Estline, E.R.6    Hirschberg, D.L.7    Steinman, L.8
  • 10
    • 0030612473 scopus 로고    scopus 로고
    • An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
    • Gong J.H., Ratkay L.G., Waterfield J.D., Clark-Lewis I. An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J. Exp. Med. 186:1997;131-137.
    • (1997) J. Exp. Med. , vol.186 , pp. 131-137
    • Gong, J.H.1    Ratkay, L.G.2    Waterfield, J.D.3    Clark-Lewis, I.4
  • 11
    • 0033062129 scopus 로고    scopus 로고
    • Expansion of neonatal tolerance to self in adult life: II. Tolerance preferentially spreads in an intramolecular manner
    • Grabie N., Karin N. Expansion of neonatal tolerance to self in adult life. II. Tolerance preferentially spreads in an intramolecular manner Int. Immunol. 11:1999;907-913.
    • (1999) Int. Immunol. , vol.11 , pp. 907-913
    • Grabie, N.1    Karin, N.2
  • 12
    • 0033037807 scopus 로고    scopus 로고
    • Expansion of neonatal tolerance to self in adult life: I. The role of a bacterial adjuvant in tolerance spread
    • Grabie N., Wohl I., Youssef S., Wildbaum G., Karin N. Expansion of neonatal tolerance to self in adult life. I. The role of a bacterial adjuvant in tolerance spread Int. Immunol. 11:1999;899-906.
    • (1999) Int. Immunol. , vol.11 , pp. 899-906
    • Grabie, N.1    Wohl, I.2    Youssef, S.3    Wildbaum, G.4    Karin, N.5
  • 14
    • 0031874342 scopus 로고    scopus 로고
    • Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry
    • Horwitz M.S., Bradley L.M., Harbertson J., Krahl T., Lee J., Sarvetnick N. Diabetes induced by Coxsackie virus. initiation by bystander damage and not molecular mimicry Nat. Med. 4:1998;781-785.
    • (1998) Nat. Med. , vol.4 , pp. 781-785
    • Horwitz, M.S.1    Bradley, L.M.2    Harbertson, J.3    Krahl, T.4    Lee, J.5    Sarvetnick, N.6
  • 16
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson L., Klein R.S., Charo I.F., Weiner H.L., Luster A.D. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J. Exp. Med. 192:2000;1075-1080.
    • (2000) J. Exp. Med. , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 17
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • Karpus W.J., Lukacs N.W., McRae B.L., Strieter R.M., Kunkel S.L., Miller S.D. An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155:1995;5003-5010.
    • (1995) J. Immunol. , vol.155 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    Mcrae, B.L.3    Strieter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 18
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-gamma confers resistance to experimental allergic encephalomyelitis
    • Krakowski M., Owens T. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur. J. Immunol. 26:1996;1641-1646.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 20
    • 84961016706 scopus 로고
    • Development of arthritis, periarthritis and periostitis in rats given adjuvants
    • Pearson C.M. Development of arthritis, periarthritis and periostitis in rats given adjuvants. Proc. Soc. Exp. Biol. Med. 91:1956;95-101.
    • (1956) Proc. Soc. Exp. Biol. Med. , vol.91 , pp. 95-101
    • Pearson, C.M.1
  • 22
    • 0029991928 scopus 로고    scopus 로고
    • Neonatal tolerance revisited: Turning on newborn T cells with dendritic cells
    • Ridge J.P., Fuchs E.J., Matzinger P. Neonatal tolerance revisited. turning on newborn T cells with dendritic cells Science. 271:1996;1723-1726.
    • (1996) Science , vol.271 , pp. 1723-1726
    • Ridge, J.P.1    Fuchs, E.J.2    Matzinger, P.3
  • 23
    • 0036721708 scopus 로고    scopus 로고
    • Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis
    • Salomon I., Netzer N., Wildbaum G., Schif-Zuck S., Maor G., Karin N. Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis. J. Immunol. 169:2002;2685-2693.
    • (2002) J. Immunol. , vol.169 , pp. 2685-2693
    • Salomon, I.1    Netzer, N.2    Wildbaum, G.3    Schif-Zuck, S.4    Maor, G.5    Karin, N.6
  • 25
    • 0030002897 scopus 로고    scopus 로고
    • Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: Implications for antibody vs. T cell-mediated autoimmunity
    • Singh R.R., Hahn B.H., Sercarz E.E. Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation. implications for antibody vs. T cell-mediated autoimmunity J. Exp. Med. 183:1996;1613-1621.
    • (1996) J. Exp. Med. , vol.183 , pp. 1613-1621
    • Singh, R.R.1    Hahn, B.H.2    Sercarz, E.E.3
  • 26
    • 0028979331 scopus 로고
    • Escape from "horror autotoxicus": Pathogenesis and treatment of autoimmune disease
    • Steinman L. Escape from "horror autotoxicus" pathogenesis and treatment of autoimmune disease Cell. 80:1995;7-10.
    • (1995) Cell , vol.80 , pp. 7-10
    • Steinman, L.1
  • 27
    • 0033954469 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
    • Suvannavejh G.C., Dal Canto M.C., Matis L.A., Miller S.D. Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. J. Clin. Invest. 105:2000;223-231.
    • (2000) J. Clin. Invest. , vol.105 , pp. 223-231
    • Suvannavejh, G.C.1    Dal Canto, M.C.2    Matis, L.A.3    Miller, S.D.4
  • 28
    • 0036216769 scopus 로고    scopus 로고
    • Phagocytosis of microbes: Complexity in action
    • Underhill D.M., Ozinsky A. Phagocytosis of microbes. complexity in action Annu. Rev. Immunol. 20:2002;825-852.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 825-852
    • Underhill, D.M.1    Ozinsky, A.2
  • 29
    • 0036481263 scopus 로고    scopus 로고
    • Epitope spreading in immune-mediated diseases: Implications for immunotherapy
    • Vanderlugt C.L., Miller S.D. Epitope spreading in immune-mediated diseases. implications for immunotherapy Nat. Rev. Immunol. 2:2002;85-95.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 85-95
    • Vanderlugt, C.L.1    Miller, S.D.2
  • 30
    • 0021321027 scopus 로고
    • Preparations of lymphotoxin induce resistance to their own cytotoxic effect
    • Wallach D. Preparations of lymphotoxin induce resistance to their own cytotoxic effect. J. Immunol. 132:1984;2464-2469.
    • (1984) J. Immunol. , vol.132 , pp. 2464-2469
    • Wallach, D.1
  • 33
    • 0032400918 scopus 로고    scopus 로고
    • Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis
    • Wildbaum G., Youssef S., Grabie N., Karin N. Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis. J. Immunol. 161:1998;6368-6374.
    • (1998) J. Immunol. , vol.161 , pp. 6368-6374
    • Wildbaum, G.1    Youssef, S.2    Grabie, N.3    Karin, N.4
  • 34
    • 0033058502 scopus 로고    scopus 로고
    • Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis
    • Wildbaum G., Karin N. Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis. Gene Ther. 6:1999;1128-1138.
    • (1999) Gene Ther. , vol.6 , pp. 1128-1138
    • Wildbaum, G.1    Karin, N.2
  • 35
    • 0033818187 scopus 로고    scopus 로고
    • A targeted DNA vaccine encoding fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis
    • a
    • Wildbaum G., Westermann J., Maor G., Karin N. A targeted DNA vaccine encoding fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis. J. Clin. Invest. 106:2000;671-679. a.
    • (2000) J. Clin. Invest. , vol.106 , pp. 671-679
    • Wildbaum, G.1    Westermann, J.2    Maor, G.3    Karin, N.4
  • 36
    • 0034669914 scopus 로고    scopus 로고
    • A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritis
    • b
    • Wildbaum G., Youssef S., Karin N. A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritis. J. Immunol. 165:2000;5860-5866. b.
    • (2000) J. Immunol. , vol.165 , pp. 5860-5866
    • Wildbaum, G.1    Youssef, S.2    Karin, N.3
  • 37
    • 0036732037 scopus 로고    scopus 로고
    • Tr1 cell-dependent active tolerance blunts the pathogenic effects of determinant spreading
    • b
    • Wildbaum G., Netzer N., Karin N. Tr1 cell-dependent active tolerance blunts the pathogenic effects of determinant spreading. J. Clin. Invest. 110:2002;701-710. b.
    • (2002) J. Clin. Invest. , vol.110 , pp. 701-710
    • Wildbaum, G.1    Netzer, N.2    Karin, N.3
  • 38
    • 0036604393 scopus 로고    scopus 로고
    • Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis
    • a
    • Wildbaum G., Netzer N., Karin N. Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis. J. Immunol. 168:2002;5885-5892. a.
    • (2002) J. Immunol. , vol.168 , pp. 5885-5892
    • Wildbaum, G.1    Netzer, N.2    Karin, N.3
  • 39
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig K.W., Strominger J.L. Molecular mimicry in T cell-mediated autoimmunity. viral peptides activate human T cell clones specific for myelin basic protein Cell. 80:1995;695-705.
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 40
    • 0032532308 scopus 로고    scopus 로고
    • Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines
    • Youssef S., Wildbaum G., Maor G., Lanir N., Gour-Lavie A., Grabie N., Karin N. Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines. J. Immunol. 161:1998;3870-3879.
    • (1998) J. Immunol. , vol.161 , pp. 3870-3879
    • Youssef, S.1    Wildbaum, G.2    Maor, G.3    Lanir, N.4    Gour-Lavie, A.5    Grabie, N.6    Karin, N.7
  • 41
    • 0033846366 scopus 로고    scopus 로고
    • C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis
    • Youssef S., Maor G., Wildbaum G., Grabie N., Gour-Lavie A., Karin N. C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis. J. Clin. Invest. 106:2000;361-371.
    • (2000) J. Clin. Invest. , vol.106 , pp. 361-371
    • Youssef, S.1    Maor, G.2    Wildbaum, G.3    Grabie, N.4    Gour-Lavie, A.5    Karin, N.6


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