Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

Journal of Experimental Medicine

Volumn 198, Issue 12, 2003, Pages 1951-1957

  Murphy, Craig A ^a   Langrish, Claire L ^a   Chen, Yi ^a   Blumenschein, Wendy ^a   McClanahan, Terrill ^a   Kastelein, Robert A ^a   Sedgwick, Jonathon D ^a   Cua, Daniel J ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE   (United States)

Author keywords

Collagen induced arthritis; Gene deficient mice; IFN ; IL 17; IL 23 gene; Rheumatoid arthritis

Indexed keywords

CD4 ANTIGEN; COLLAGEN; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN RECEPTOR; MESSENGER RNA; PROTEIN P19; PROTEIN P35; PROTEIN P40; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE MODEL; FEMALE; GENE TARGETING; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TH1 CELL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; COLLAGEN TYPE II; FEMALE; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-23 SUBUNIT P19; INTERLEUKINS; MALE; MICE; MICE, INBRED C57BL; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0346962972     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030896     Document Type: Article

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