Transforming Growth Factor β1 (TGFβ1) Gene Expression by Eosinophils in Asthmatic Airway Inflammation

American Journal of Respiratory Cell and Molecular Biology

Volumn 15, Issue 3, 1996, Pages 404-409

  Ohno, Isao ^b   Nitta, Yuko ^b   Yamauchi, Kohei ^b   Hoshi, Hiroki ^b   Honma, Masaaki ^b   Woolley, Karen ^b   O'Byrne, Paul ^b   Tamura, Gen ^b   Jordana, Manel ^b   Shirato, Kunio ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; ASTHMA; BRONCHUS; CELL STRAIN HL 60; CYTOCHEMISTRY; EOSINOPHIL; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; IN SITU HYBRIDIZATION; INFLAMMATION; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; ASTHMA; BRONCHI; EOSINOPHILS; FEMALE; GENE EXPRESSION; HISTOCYTOCHEMISTRY; HL-60 CELLS; HUMANS; IN SITU HYBRIDIZATION; INFLAMMATION; MALE; MIDDLE AGED; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030236307     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.15.3.8810646     Document Type: Article

References (35)

1. Arm, J. P., and T. H. Lee. 1992. The pathology of bronchial asthma. Adv. Immunol. 51:323-382.
2. Wiggs, B. R., C. Bosken, P. D. Pare, A. James, and J. C. Hogg. 1992. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 145:1251-1258.
3. Aubert, J.-D., B. I. Dalal, T. R. Bai, C. R. Roberts, S. Hayashi, and J. C. Hogg. 1994. Transforming growth factor β1 gene expression in human airways. Thorax 49:225-232.
4. Aubert, J.-D., S. Hayashi, J. Hards, T. R. Bai, P. D. Pare, and J. C. Hogg. 1994. Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction. Am. J. Physiol. 266:L655-L663.
5. Ohno, I., Y. Nina, K. Yamauchi, H. Hoshi, M. Honma, K. Woolley, P. O'Byrne, J. Dolovich, M. Jordana, G. Tamura, Y. Tanno, and K. Shirato. 1995. Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma. Am. J. Respir. Cell Mol. Biol. 13:639-647.
6. Barnard, J. A., R. M. Ryons, and H. L. Moses. 1990. The cell biology of transforming growth factor β. Biochim. Biophys. Acta 1032:79-87.
7. Wahl, S. M. 1992. Transforming growth factor beta (TGF-β) in inflammation: a cause and a cure. J. Clin. Immunol. 12:61-74.
8. Desmouliere, A., A. Geinoz, F. Gabbiani, and G. Gabbiani. 1993. Transforming growth factor-β1 induces α-amooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J. Cell Biol. 122:103-111.
9. Broekelmann, T. J., A. H. Limper, T. V. Colby, and J. A. McDonald. 1991. Transforming growth factor β1 is present at the site of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl. Acad. Sci. USA 88:6642-6646.
10. Khalil, N., R. N. O'Connor, H. W. Unruh, P. W. Warren, K. C. Flanders, A. Kemp, O. H. Bereznay, and A. H. Greenberg. 1991. Increased production and immunohistochemical localization of transforming growth factor-β in idiopathic pulmonary fibrosis. Am. J. Respir. Cell Mol. Biol. 5:155-162.
11. Roche, W. R., R. Beasley, J. H. Williams, and S. T. Holgate. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 8637i:520-524.
12. Brewster, C. E. P., P. H. Howarth, R. Djukanovic, J. Wilson, S. T. Holgate, and W. R. Roche. 1990. Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 3:507-511.
13. Ohno, I., R. G. Lea, K. C. Flanders, D. A. Clark, D. Banwatt, J. Dolovich, J. Denburg, C. B. Harley, J. Gauldie, and M. Jordana. 1992. Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor β1 gene (TGFβ1). J. Clin. Invest. 89:1662-1668.
14. Wong, D. T. W., R, B. Donoff, J. Yang, B.-Z. Song, K. Matossian, N. Nagura, G. Gallagher, R. Todd, T. Chiang, L. S.-S. Chou, C. M. Yung, S. J. Galli, and P. F. Weller. 1993. Sequential expression of transforming growth factors α and β1 by eosinophils during cutaneous wound healing in the hamster. Am. J. Pathol. 143:130-142.
15. Zhang, K., K. C. Flanders, and S. H. Phan. 1995. Cellular localization of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 147:352-361.
16. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Medical Section of the American Lung Association. 1987. Am. Rev. Respir. Dis. 136:225-243.
17. Woolley, K. L., E. Adelroth, M. J. Woolley, R. Ellis, M. Jordana, and P. M. O'Byrne. 1995. Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma. Am. J. Respir. Crit. Care Med. 151:1915-1924.
18. Ohkawara, Y., K. Yamauchi, N. Maruyama, H. Hoshi, I. Ohno, M. Honma, Y. Tanno, G. Tamura, K. Shirato, and H. Ohtani. 1995. In situ expression of the cell adhesion molecules in bronchial tissues from asthmatics with air flow limitation: in vivo evidence of VCAM-I/VLA-4 interaction in selective eosinophil infiltration. Am. J. Respir. Cell Mol. Biol. 12:4-12.
19. Kondaiah, P., E. Van Obberghen-Schilling, R. L. Ludwig, R. Dhar, M. B. Sporn, and A. B. Roberts. 1988. cDNA cloning of porcine transforming growth factor-β1 mRNAs: evidence for alternate splicing and polyadenylation. J. Biol. Chem. 34:18313-18317.
20. Haynes, A. R., and R. J. Shaw. 1992. Dexamethasone-induced increase in platelet-derived growth factor (B) mRNA in human alveolar macrophages and myelomonocytic HL60 macrophage-like cells. Am. J. Respir. Cell Mol. Biol. 7:198-206.
21. Wong, D. T. W., A. Elovic, K. Matossian, N. Nagura, J. McBride, M. Y. Chou, J. R. Gordon, T. H. Rand, S. J. Galli, and P. F. Weller. 1991. Eosinophils from patients with blood eosinophilia express transforming growth factor β1. Blood 78:2702-2707.
22. Phan, S. H., M. Gharaee-Kermani, F. Wolber, and U. S. Ryan. 1991. Stimulation of rat endothelial cell transforming growth factor-β production by bleomycin. J. Clin. Invest. 87:148-154.
23. Assoian, R. K., B. E. Frolik, H. C. Stevenson, D. K. Miller, E. W. Medtes, R. R. Raines, and M. B. Sporn. 1987. Expression and secretion of type beta transforming growth factor by activated human macrophages. Proc. Natl. Acad. Sci. USA 84:6020-6024.
24. Hirst, S. J., P. J. Barnes, and C. H. C. Twort. 1992. Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor. Am. J. Respir. Cell Mol. Biol. 7:574-581.
25. Ross, R., E. W. Raines, and D. F. Bowen-Pope. 1986. The biology of platelet-derived growth factor. Cell 46:155-169.
26. Powell, P. P., M. Klagsburn, J. A. Abraham, and R. C. Jones. 1993. Eosinophils expressing heparin-binding EGF-like growth factor mRNA localize around lung microvessels in pulmonary hypertension. Am. J. Pathol. 143:784-793.
27. Kay, A. B. 1991. Asthma and inflammation. J. Allergy Clin. Immunol. 87: 893-910.
28. Broide, D. H., S. I. Wasserman, J. Alvaro-Gracia, N. J. Zvaifler, and G. S. Firestein. 1989. Transforming growth factor-β1 selectively inhibits IL-3-dependent mast cell proliferation without affecting mast cell function or differentiation. J. Immunol. 143:1591-1597.
29. Gruber, B. L., M. J. Marchese, and R. R. Kew. 1994. Transforming growth factor-β1 mediates mast cell chemotaxis. J. Immunol. 152:5860-5867.
30. Tanaka, M., K. Lee, J. Yodoi, H. Sito, Y. Iwai, K.-M. Kim, M. Morita, M. Mayumi, and H. Mikawa. 1989. Regulation of Fcε receptor II (CD23) expression on a human eosinophilic cell line EoL3 and a human monocytic cell line U937 by transforming growth factor β. Cell. Immunol. 122: 96-107.
31. Alam, R., P. Forsythe, S. Stafford, and Y. Fukuda. 1994. Transforming growth factor β abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J. Exp. Med. 179:1041-1045.
32. Sillaber, C., K. Geissler, R. Scherrer, R. Kaltenbrunner, P. Bettelheim, K. Lechner, and P. Valent. 1992. Type β transforming growth factors promote interleukin-3 (IL-3)-dependent differentiation of human basophils but inhibit IL-3-dependent differentiation of human eosinophils. Blood 80: 634-641.
33. Gamble, J. R., Y. Khew-Goodall, and M. A. Vadas. 1993. Transforming growth factor-β inhibits E-selectin expression on human endothelial cells. J. Immunol. 150:4494-4503.
34. Bradding, P., J. A. Roberts, K. M. Britten, S. Montefort, R. Djukanovic, R. Mueller, C. H. Heusser, P. H. Howarth, and S. T. Holgate. 1994. Interleukin-4, -5, and -6 and tumor necrosis factor-a in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am. J. Respir. Cell Mol. Biol. 10:471-480.
35. Sousa, A. R., R. N. Poston, S. J. Lane, J. A. Nakhosteen, and T. H. Lee. 1993. Detection of GM-CSF in asthmatic bronchial epithelium and decreased by inhaled corticosteroids. Am. Rev. Respir. Dis. 147:1557-1561.