-
1
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald, T.T., and G. Monteleone. 2005. Immunity, inflammation, and allergy in the gut. Science. 307:1920-1925.
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.T.1
Monteleone, G.2
-
2
-
-
23344449020
-
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
-
Elson, C.O., Y. Cong, V.J. McCracken, R.A. Dimmitt, R.G. Lorenz, and C.T. Weaver. 2005. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol. Rev. 206:260-276.
-
(2005)
Immunol. Rev.
, vol.206
, pp. 260-276
-
-
Elson, C.O.1
Cong, Y.2
McCracken, V.J.3
Dimmitt, R.A.4
Lorenz, R.G.5
Weaver, C.T.6
-
4
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
Bouma, G., and W. Strober. 2003. The immunological and genetic basis of inflammatory bowel disease. Nat. Rev. Immunol. 3:521-533.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
5
-
-
0028861975
-
Antibodies to interleukin-12 abrogate established experimental colitis in mice
-
Neurath, M.F., I. Fuss, B.L. Kelsall, E. Stuber, and W. Strober. 1995. Antibodies to interleukin-12 abrogate established experimental colitis in mice. J. Exp. Med. 182:1281-1290.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
6
-
-
0032550312
-
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin-12-signal transducer and activator of transcription (Stat)-4 pathway but is not conditional on interferon γ expression by T cells
-
Simpson, S.J., S. Shah, M. Comiskey, Y.P. de Jong, B. Wang, E. Mizoguchi, A.K. Bhan, and C. Terhorst. 1998. T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin-12-signal transducer and activator of transcription (Stat)-4 pathway but is not conditional on interferon γ expression by T cells. J. Exp. Med. 187:1225-1234.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1225-1234
-
-
Simpson, S.J.1
Shah, S.2
Comiskey, M.3
De Jong, Y.P.4
Wang, B.5
Mizoguchi, E.6
Bhan, A.K.7
Terhorst, C.8
-
7
-
-
0034972172
-
Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation
-
Kullberg, M.C., A.G. Rothfuchs, D. Jankovic, P. Caspar, T.A. Wynn, P.L. Gorelick, A.W. Cheever, and A. Sher. 2001. Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: cytokine requirements for the induction and maintenance of intestinal inflammation. Infect. Immun. 69:4232-4241.
-
(2001)
Infect. Immun.
, vol.69
, pp. 4232-4241
-
-
Kullberg, M.C.1
Rothfuchs, A.G.2
Jankovic, D.3
Caspar, P.4
Wynn, T.A.5
Gorelick, P.L.6
Cheever, A.W.7
Sher, A.8
-
9
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
Mannon, P.J., I.J. Fuss, L. Mayer, C.O. Elson, W.J. Sandborn, D. Present, B. Dolin, N. Goodman, C. Groden, R.L. Hornung, et al. 2004. Anti-interleukin-12 antibody for active Crohn's disease. N. Engl. J. Med. 351:2069-2079.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
Dolin, B.7
Goodman, N.8
Groden, C.9
Hornung, R.L.10
-
10
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., R. Lesley, B. Blom, J.C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, K. Singh, et al. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 13:715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
-
11
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D.J., J. Sherlock, Y. Chen, C.A. Murphy, B. Joyce, B. Seymour, L. Lucian, W. To, S. Kwan, T. Churakova, et al. 2003. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
12
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C.L., Y. Chen, W.M. Blumenschein, J. Mattson, B. Basham, J.D. Sedgwick, T. McClanahan, R.A. Kastelein, and D.J. Cua. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201:233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
13
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy, C.A., C.L. Langrish, Y. Chen, W. Blumenschein, T. McClanahan, R.A. Kastelein, J.D. Sedgwick, and D.J. Cua. 2003. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198:1951-1957.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
14
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
Wiekowski, M.T., M.W. Leach, E.W. Evans, L. Sullivan, S.C. Chen, G. Vassileva, J.F. Bazan, D.M. Gorman, R.A. Kastelein, S. Narula, and S.A. Lira. 2001. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J. Immunol. 166:7563-7570.
-
(2001)
J. Immunol.
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
Bazan, J.F.7
Gorman, D.M.8
Kastelein, R.A.9
Narula, S.10
Lira, S.A.11
-
15
-
-
13244290058
-
IL-12- and IL-23-induced T helper cell subsets: Birds of the same feather flock together
-
Bettelli, E., and V.K. Kuchroo. 2005. IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together. J. Exp. Med. 201:169-171.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 169-171
-
-
Bettelli, E.1
Kuchroo, V.K.2
-
18
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Z. Li, X.O. Yang, S.H. Chang, R. Nurieva, Y.H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6:1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
19
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., N. Ghilardi, M.H. Xie, F.J. de Sauvage, and A.L. Gurney. 2003. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278:1910-1914.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
20
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen, M., R.J. Hocking, C.J. Atkins, R.M. Locksley, and B. Stockinger. 2006. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24:179-189.
-
(2006)
Immunity.
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
21
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan, P.R., L.E. Harrington, D.B. O'Quinn, W.S. Helms, D.C. Bullard, C.O. Elson, R.D. Hatton, S.M. Wahl, T.R. Schoeb, and C.T. Weaver. 2006. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
22
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Y. Carrier, W. Gao, T. Korn, T.B. Strom, M. Oukka, H.L. Weiner, and V.K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
23
-
-
33744489569
-
TGF-beta, a 'double agent' in the immune pathology war
-
Cua, D.J., and R.A. Kastelein. 2006. TGF-beta, a 'double agent' in the immune pathology war. Nat. Immunol. 7:557-559.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 557-559
-
-
Cua, D.J.1
Kastelein, R.A.2
-
24
-
-
0037655006
-
Effects of IL-12 and IL-23 on antigen-presenting cells at the interface between innate and adaptive immunity
-
Puccetti, P., M.L. Belladonna, and U. Grohmann. 2002. Effects of IL-12 and IL-23 on antigen-presenting cells at the interface between innate and adaptive immunity. Crit. Rev. Immunol. 22:373-390.
-
(2002)
Crit. Rev. Immunol.
, vol.22
, pp. 373-390
-
-
Puccetti, P.1
Belladonna, M.L.2
Grohmann, U.3
-
25
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot, J.P., M. Chamaillard, H. Zouali, S. Lesage, J.P. Cezard, J. Belaiche, S. Almer, C. Tysk, C.A. O'Morain, M. Gassull, et al. 2001. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 411:599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
-
26
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura, Y., D.K. Bonen, N. Inohara, D.L. Nicolae, F.F. Chen, R. Ramos, H. Britton, T. Moran, R. Karaliuskas, R.H. Duerr, et al. 2001. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 411:603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
-
27
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin, S.E., I.G. Boneca, J. Viala, M. Chamaillard, A. Labigne, G. Thomas, D.J. Philpott, and P.J. Sansonetti. 2003. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278:8869-8872.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
Philpott, D.J.7
Sansonetti, P.J.8
-
28
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K.S., M. Chamaillard, Y. Ogura, O. Henegariu, N. Inohara, G. Nunez, and R.A. Flavell. 2005. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 307:731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
29
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
Maeda, S., L.C. Hsu, H. Liu, L.A. Bankston, M. Iimura, M.F. Kagnoff, L. Eckmann, and M. Karin. 2005. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science. 307:734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
31
-
-
0037331279
-
+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice
-
+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice. Am. J. Pathol. 162:691-702.
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 691-702
-
-
Erdman, S.E.1
Poutahidis, T.2
Tomczak, M.3
Rogers, A.B.4
Cormier, K.5
Plank, B.6
Horwitz, B.H.7
Fox, J.G.8
-
32
-
-
0141835046
-
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
-
Becker, C., S. Wirtz, M. Blessing, J. Pirhonen, D. Strand, O. Bechthold, J. Frick, P.R. Galle, I. Autenrieth, and M.F. Neurath. 2003. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J. Clin. Invest. 112:693-706.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 693-706
-
-
Becker, C.1
Wirtz, S.2
Blessing, M.3
Pirhonen, J.4
Strand, D.5
Bechthold, O.6
Frick, J.7
Galle, P.R.8
Autenrieth, I.9
Neurath, M.F.10
-
33
-
-
13944281011
-
Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
-
Schmidt, C., T. Giese, B. Ludwig, I. Mueller-Molaian, T. Marth, S. Zeuzem, S.C. Meuer, and A. Stallmach. 2005. Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm. Bowel Dis. 11:16-23.
-
(2005)
Inflamm. Bowel Dis.
, vol.11
, pp. 16-23
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
Mueller-Molaian, I.4
Marth, T.5
Zeuzem, S.6
Meuer, S.C.7
Stallmach, A.8
-
34
-
-
29744450121
-
Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
-
Fuss, I.J., C. Becker, Z. Yang, C. Groden, R.L. Hornung, F. Heller, M.F. Neurath, W. Strober, and P.J. Mannon. 2006. Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody. Inflamm. Bowel Dis. 12:9-15.
-
(2006)
Inflamm. Bowel Dis.
, vol.12
, pp. 9-15
-
-
Fuss, I.J.1
Becker, C.2
Yang, Z.3
Groden, C.4
Hornung, R.L.5
Heller, F.6
Neurath, M.F.7
Strober, W.8
Mannon, P.J.9
-
37
-
-
9644291539
-
IL-12 and IL-23: Master regulators of innate and adaptive immunity
-
Langrish, C.L., B.S. McKenzie, N.J. Wilson, R. de Waal Malefyt, R.A. Kastelein, and D.J. Cua. 2004. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol. Rev. 202:96-105.
-
(2004)
Immunol. Rev.
, vol.202
, pp. 96-105
-
-
Langrish, C.L.1
McKenzie, B.S.2
Wilson, N.J.3
De Waal Malefyt, R.4
Kastelein, R.A.5
Cua, D.J.6
-
38
-
-
0038623916
-
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
-
Nakae, S., S. Saijo, R. Horai, K. Sudo, S. Mori, and Y. Iwakura. 2003. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Natl. Acad. Sci. USA. 100:5986-5990.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5986-5990
-
-
Nakae, S.1
Saijo, S.2
Horai, R.3
Sudo, K.4
Mori, S.5
Iwakura, Y.6
-
39
-
-
0037442137
-
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger
-
Ferretti, S., O. Bonneau, G.R. Dubois, C.E. Jones, and A. Trifilieff. 2003. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger. J. Immunol. 170:2106-2112.
-
(2003)
J. Immunol.
, vol.170
, pp. 2106-2112
-
-
Ferretti, S.1
Bonneau, O.2
Dubois, G.R.3
Jones, C.E.4
Trifilieff, A.5
-
40
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
Fujino, S., A. Andoh, S. Bamba, A. Ogawa, K. Hata, Y. Araki, T. Bamba, and Y. Fujiyama. 2003. Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 52:65-70.
-
(2003)
Gut
, vol.52
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
Bamba, T.7
Fujiyama, Y.8
-
41
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
Kolls, J.K., and A. Linden. 2004. Interleukin-17 family members and inflammation. Immunity. 21:467-476.
-
(2004)
Immunity
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Linden, A.2
-
42
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., J. Cheung, H. Scheerens, F. Poulet, T. McClanahan, B. McKenzie, M.A. Kleinschek, A. Owyang, J. Mattson, W. Blumenschein, et al. 2006. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116:1310-1316.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
-
43
-
-
33750530394
-
IL-23 is a key mediator of Helicobacter hepaticus-induced T cell-dependent colitis
-
Kullberg, M.C., D. Jankovic, C.G. Feng, S. Hue, P.L. Gorelick, B.S. McKenzie, D.J. Cua, F. Powrie, A.W. Cheever, K.J. Maloy, and A. Sher. 2006. IL-23 is a key mediator of Helicobacter hepaticus-induced T cell-dependent colitis. J. Exp. Med. 203:2485-2494.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2485-2494
-
-
Kullberg, M.C.1
Jankovic, D.2
Feng, C.G.3
Hue, S.4
Gorelick, P.L.5
McKenzie, B.S.6
Cua, D.J.7
Powrie, F.8
Cheever, A.W.9
Maloy, K.J.10
Sher, A.11
-
44
-
-
0842324613
-
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
-
Ogawa, A., A. Andoh, Y. Araki, T. Bamba, and Y. Fujiyama. 2004. Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice. Clin. Immunol. 110:55-62.
-
(2004)
Clin. Immunol.
, vol.110
, pp. 55-62
-
-
Ogawa, A.1
Andoh, A.2
Araki, Y.3
Bamba, T.4
Fujiyama, Y.5
-
45
-
-
0034128634
-
Claudins regulate the intestinal barrier in response to immune mediators
-
Kinugasa, T., T. Sakaguchi, X. Gu, and H.C. Reinecker. 2000. Claudins regulate the intestinal barrier in response to immune mediators. Gastroenterology. 118:1001-1011.
-
(2000)
Gastroenterology
, vol.118
, pp. 1001-1011
-
-
Kinugasa, T.1
Sakaguchi, T.2
Gu, X.3
Reinecker, H.C.4
-
46
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198:1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
48
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Wan, Y.Y., and R.A. Flavell. 2005. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. USA. 102:5126-5131.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
50
-
-
33747089041
-
Differential acitvity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
-
Uhlig, H., B.S. McKenzie, S. Hue, C. Thompson, R. Stepankova, N.J. Robinson, H. Tlaskalova-Hogenova, D.J. Cua, and F. Powrie. 2006. Differential acitvity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity. 25:309-318.
-
(2006)
Immunity
, vol.25
, pp. 309-318
-
-
Uhlig, H.1
McKenzie, B.S.2
Hue, S.3
Thompson, C.4
Stepankova, R.5
Robinson, N.J.6
Tlaskalova-Hogenova, H.7
Cua, D.J.8
Powrie, F.9
-
51
-
-
27744437941
-
Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria
-
Kamada, N., T. Hisamatsu, S. Okamoto, T. Sato, K. Matsuoka, K. Arai, T. Nakai, A. Hasegawa, N. Inoue, N. Watanabe, et al. 2005. Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria. J. Immunol. 175:6900-6908.
-
(2005)
J. Immunol.
, vol.175
, pp. 6900-6908
-
-
Kamada, N.1
Hisamatsu, T.2
Okamoto, S.3
Sato, T.4
Matsuoka, K.5
Arai, K.6
Nakai, T.7
Hasegawa, A.8
Inoue, N.9
Watanabe, N.10
-
52
-
-
25144515561
-
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
-
Happel, K. I., P.J. Dubin, M. Zheng, N. Ghilardi, C. Lockhart, L.J. Quinton, A.R. Odden, J.E. Shellito, G.J. Bagby, S. Nelson, and J.K. Kolls. 2005. Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J. Exp. Med. 202:761-769.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 761-769
-
-
Happel, K.I.1
Dubin, P.J.2
Zheng, M.3
Ghilardi, N.4
Lockhart, C.5
Quinton, L.J.6
Odden, A.R.7
Shellito, J.E.8
Bagby, G.J.9
Nelson, S.10
Kolls, J.K.11
-
53
-
-
3042527166
-
Infectious complications of treatment with biologic agents
-
Hamilton, C.D. 2004. Infectious complications of treatment with biologic agents. Curr. Opin. Rheumatol. 16:393-398.
-
(2004)
Curr. Opin. Rheumatol.
, vol.16
, pp. 393-398
-
-
Hamilton, C.D.1
-
54
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133-146.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
55
-
-
2142758715
-
In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants
-
Young, V.B., K.A. Knox, J.S. Pratt, J.S. Cortez, L.S. Mansfield, A.B. Rogers, J.G. Fox, and D.B. Schauer. 2004. In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants. Infect. Immun. 72:2521-2527.
-
(2004)
Infect. Immun.
, vol.72
, pp. 2521-2527
-
-
Young, V.B.1
Knox, K.A.2
Pratt, J.S.3
Cortez, J.S.4
Mansfield, L.S.5
Rogers, A.B.6
Fox, J.G.7
Schauer, D.B.8
-
56
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen, Y., C.L. Langrish, B. McKenzie, B. Joyce-Shaikh, J.S. Stumhofer, T. McClanahan, W. Blumenschein, T. Churakovsa, J. Low, L. Presta, et al. 2006. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J. Clin. Invest. 116:1317-1326.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.6
Blumenschein, W.7
Churakovsa, T.8
Low, J.9
Presta, L.10
-
57
-
-
0034679567
-
+ regulatory cells that control intestinal inflammation
-
+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
58
-
-
0030590652
-
Flow cytometric identification of murine neutrophils and monocytes
-
Lagasse, E., and I.L. Weissman. 1996. Flow cytometric identification of murine neutrophils and monocytes. J. Immunol. Methods. 197:139-150.
-
(1996)
J. Immunol. Methods.
, vol.197
, pp. 139-150
-
-
Lagasse, E.1
Weissman, I.L.2
-
59
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, M.W. 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29:e45.
-
(2001)
Nucleic Acids Res.
, vol.29
-
-
Pfaffl, M.W.1
-
60
-
-
0034951122
-
Fluorogenic PCR-based quantitative detection of a murine pathogen, Helicobacter hepaticus
-
Ge, Z., D.A. White, M.T. Whary, and J.G. Fox. 2001. Fluorogenic PCR-based quantitative detection of a murine pathogen, Helicobacter hepaticus. J. Clin. Microbiol. 39:2598-2602.
-
(2001)
J. Clin. Microbiol.
, vol.39
, pp. 2598-2602
-
-
Ge, Z.1
White, D.A.2
Whary, M.T.3
Fox, J.G.4
|