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Volumn 47, Issue 6, 1998, Pages 582-590

Interleukin-12 and perforin mRNA expression is augmented in blood mononuclear cells in multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; MESSENGER RNA; PERFORIN;

EID: 0031800907     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1998.00344.x     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996;85:299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 2
    • 0028288179 scopus 로고    scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S. Lymphokine production by human T cells in disease states. Immunol Today 1997;12:227-57.
    • (1997) Immunol Today , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 3
    • 0029762023 scopus 로고    scopus 로고
    • Cytokines and the pathogenesis of multiple sclerosis
    • Navikas V, Link H. Cytokines and the pathogenesis of multiple sclerosis. J Neurosci Research 1996;45:322-33.
    • (1996) J Neurosci Research , vol.45 , pp. 322-333
    • Navikas, V.1    Link, H.2
  • 4
    • 0026701132 scopus 로고
    • Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells
    • D'Andrea A, Rengaraju M, Valiante NM et al. Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells. J Exp Med 1992;176:1387-98.
    • (1992) J Exp Med , vol.176 , pp. 1387-1398
    • D'Andrea, A.1    Rengaraju, M.2    Valiante, N.M.3
  • 5
    • 0027491655 scopus 로고
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming. Proc Natl Acad Sci USA 1993;90:10188-92.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 6
    • 0025013169 scopus 로고
    • Autoreactive T lymphocytes in multiple sclerosis determined by antigen induced secretion of interferon-gamma
    • Olsson T, Wang W-Z, Höjeberg B et al. Autoreactive T lymphocytes in multiple sclerosis determined by antigen induced secretion of interferon-gamma. J Clin Invest 1990;86:981-5.
    • (1990) J Clin Invest , vol.86 , pp. 981-985
    • Olsson, T.1    Wang, W.-Z.2    Höjeberg, B.3
  • 7
    • 0028926524 scopus 로고
    • Interleukin-12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice
    • Trembleau S, Penna G, Bosi E, Mortara A, Gately MK, Adorini L. Interleukin-12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice. J Exp Med 1995;181:817-921.
    • (1995) J Exp Med , vol.181 , pp. 817-921
    • Trembleau, S.1    Penna, G.2    Bosi, E.3    Mortara, A.4    Gately, M.K.5    Adorini, L.6
  • 8
    • 0028966091 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin-12
    • Leonard JP, Waldburger KE, Goldman SJ. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin-12. J Exp Med 1995;181:381-6.
    • (1995) J Exp Med , vol.181 , pp. 381-386
    • Leonard, J.P.1    Waldburger, K.E.2    Goldman, S.J.3
  • 9
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin-12 in multiple sclerosis lesions
    • Windhagen A, Newcombe J, Dangond F et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin-12 in multiple sclerosis lesions. J Exp Med 1995;182:1985-96.
    • (1995) J Exp Med , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3
  • 10
    • 0004882072 scopus 로고    scopus 로고
    • Elevated levels of interleukin-12 in chronic progressive multiple sclerosis
    • Nicoletti F, Patti F, Cocuzza C et al. Elevated levels of interleukin-12 in chronic progressive multiple sclerosis. J Neuroimmunol 1996;70:87-90.
    • (1996) J Neuroimmunol , vol.70 , pp. 87-90
    • Nicoletti, F.1    Patti, F.2    Cocuzza, C.3
  • 11
    • 0342867627 scopus 로고
    • Perform and granzymes: Crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity
    • Griffiths GM, Tschopp J, eds. Berlin: Springer-Verlag
    • Lowin B, Peitch MC, Tschopp J. Perform and granzymes: crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity. In: Griffiths GM, Tschopp J, eds. Pathways for Cytolysis. Berlin: Springer-Verlag, 1995:1-25.
    • (1995) Pathways for Cytolysis , pp. 1-25
    • Lowin, B.1    Peitch, M.C.2    Tschopp, J.3
  • 14
    • 0028278373 scopus 로고
    • Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile
    • Somoza N, Vargas F, Roura-Mir C et al. Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile. J Immunol 1994;153:1360-77.
    • (1994) J Immunol , vol.153 , pp. 1360-1377
    • Somoza, N.1    Vargas, F.2    Roura-Mir, C.3
  • 15
    • 0028114746 scopus 로고
    • Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease
    • Wu Z, Podack ER, McKenzie JM, Olsen KJ, Zakarija M. Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease. Clin Exp Immunol 1994;98:470-7.
    • (1994) Clin Exp Immunol , vol.98 , pp. 470-477
    • Wu, Z.1    Podack, E.R.2    McKenzie, J.M.3    Olsen, K.J.4    Zakarija, M.5
  • 16
    • 0026778143 scopus 로고
    • Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis
    • Young LH, Joag SV, Lin PY et al. Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis. Am J Pathol 1992;140:1261-8.
    • (1992) Am J Pathol , vol.140 , pp. 1261-1268
    • Young, L.H.1    Joag, S.V.2    Lin, P.Y.3
  • 17
    • 0025215625 scopus 로고
    • Oligodendrocyte susceptibility to injury by T cell perform
    • Scolding NJ, Jones J, Compston DA, Morgan BP. Oligodendrocyte susceptibility to injury by T cell perform. Immunol 1990;70:6-10.
    • (1990) Immunol , vol.70 , pp. 6-10
    • Scolding, N.J.1    Jones, J.2    Compston, D.A.3    Morgan, B.P.4
  • 18
    • 0028077508 scopus 로고
    • IL-12 regulates T helper type 1 cytokine responses in human infectious disease
    • Sieling PA, Wang XH, Gately MK et al. IL-12 regulates T helper type 1 cytokine responses in human infectious disease. J Immunol 1994;153:3639-47.
    • (1994) J Immunol , vol.153 , pp. 3639-3647
    • Sieling, P.A.1    Wang, X.H.2    Gately, M.K.3
  • 20
    • 0028219791 scopus 로고
    • Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
    • Kägi D, Ledermann B, Burki K et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 1994;369:31-7.
    • (1994) Nature , vol.369 , pp. 31-37
    • Kägi, D.1    Ledermann, B.2    Burki, K.3
  • 21
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser CM, Paty DW, Scheinberg L et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-31.
    • (1983) Ann Neurol , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 22
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 23
    • 0021670537 scopus 로고
    • Improved detection of oligoclonal IgG in cerebrospinal fluid by isoelectric focusing in agarose, double antibody peroxidase labelling, and avidin-biotin amplification
    • Olsson T, Kostulas V, Link H. Improved detection of oligoclonal IgG in cerebrospinal fluid by isoelectric focusing in agarose, double antibody peroxidase labelling, and avidin-biotin amplification. Clin Chem 1984;30:1246-9.
    • (1984) Clin Chem , vol.30 , pp. 1246-1249
    • Olsson, T.1    Kostulas, V.2    Link, H.3
  • 24
    • 0017592811 scopus 로고
    • Principles of albumin and IgG analysis in neurological disorders. I. Establishment of reference values
    • Tibbling G, Link H, Ohman S. Principles of albumin and IgG analysis in neurological disorders. I. Establishment of reference values. Scand J Clin Lab Invest 1977;37:385-90.
    • (1977) Scand J Clin Lab Invest , vol.37 , pp. 385-390
    • Tibbling, G.1    Link, H.2    Ohman, S.3
  • 25
    • 0015264390 scopus 로고
    • Large scale preparation of myelin basic protein from central nervous tissue of several animal species
    • Deibler GE, Martensson RE, Kies MV. Large scale preparation of myelin basic protein from central nervous tissue of several animal species. Prep Biochem 1972;2:139-65.
    • (1972) Prep Biochem , vol.2 , pp. 139-165
    • Deibler, G.E.1    Martensson, R.E.2    Kies, M.V.3
  • 26
    • 0027271837 scopus 로고
    • Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor
    • Wang Z-Y, Qiao J, Link H. Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor. J Neuroimmunol 1993;44:209-14.
    • (1993) J Neuroimmunol , vol.44 , pp. 209-214
    • Wang, Z.-Y.1    Qiao, J.2    Link, H.3
  • 27
    • 0025808629 scopus 로고
    • Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor
    • Gubler U, Chua AD, Schoenhaut DS et al. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl Acad Sci USA 1991;88:4143-7.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4143-4147
    • Gubler, U.1    Chua, A.D.2    Schoenhaut, D.S.3
  • 28
    • 0024355759 scopus 로고
    • Molecular cloning and chromosomal assignment of a human perform (PFP) gene
    • Shinkai Y, Yoshida MC, Maeda K et al. Molecular cloning and chromosomal assignment of a human perform (PFP) gene. Immunogenetics 1989;30:452-7.
    • (1989) Immunogenetics , vol.30 , pp. 452-457
    • Shinkai, Y.1    Yoshida, M.C.2    Maeda, K.3
  • 29
    • 0028260294 scopus 로고
    • Organ-specific autoantigens induce interferon-γ and interleukin-4 mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis
    • Link J, Söderström M, Ljungdahl Å et al. Organ-specific autoantigens induce interferon-γ and interleukin-4 mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis. Neurology 1994;44:728-34.
    • (1994) Neurology , vol.44 , pp. 728-734
    • Link, J.1    Söderström, M.2    Ljungdahl, Å.3
  • 30
    • 0027170763 scopus 로고
    • Monocyte regulated IFN-γ production in human T cells involves CD2 signaling
    • Wingren AG, Dahlenborg K, Bjorklund M et al. Monocyte regulated IFN-γ production in human T cells involves CD2 signaling. J Immunol 1993;151:1328-36.
    • (1993) J Immunol , vol.151 , pp. 1328-1336
    • Wingren, A.G.1    Dahlenborg, K.2    Bjorklund, M.3
  • 31
    • 0028985320 scopus 로고
    • Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis associated with disease activity
    • Rieckmann P, Albrecht M, Kitze B et al. Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis associated with disease activity. Ann Neurol 1995;37:82-8.
    • (1995) Ann Neurol , vol.37 , pp. 82-88
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3
  • 32
    • 0025909739 scopus 로고
    • Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls
    • Sun JB, Olsson T, Wang WX et al. Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls. Eur J Immunol 1991;21:1461-8.
    • (1991) Eur J Immunol , vol.21 , pp. 1461-1468
    • Sun, J.B.1    Olsson, T.2    Wang, W.X.3
  • 33
    • 0025979945 scopus 로고
    • T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis
    • Sun JB, Link H, Xiao BG et al. T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis. J Immunol 1991;146:1215-22.
    • (1991) J Immunol , vol.146 , pp. 1215-1222
    • Sun, J.B.1    Link, H.2    Xiao, B.G.3
  • 34
    • 0026521206 scopus 로고
    • Virus-reactive and autoreactive T cells are accumulated in cerebrospinal fluid in multiple sclerosis
    • Link H, Sun J-B, Wang Z-Y et al. Virus-reactive and autoreactive T cells are accumulated in cerebrospinal fluid in multiple sclerosis. J Neuroimmunol 1992;38:63-73.
    • (1992) J Neuroimmunol , vol.38 , pp. 63-73
    • Link, H.1    Sun, J.-B.2    Wang, Z.-Y.3
  • 35
    • 0027953227 scopus 로고
    • Organ-specific autoantigens induce transforming growth factor-β inRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis
    • Link J, Fredrikson S, Söderström M et al. Organ-specific autoantigens induce transforming growth factor-β inRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis. Ann Neurol 1994;35:197-203.
    • (1994) Ann Neurol , vol.35 , pp. 197-203
    • Link, J.1    Fredrikson, S.2    Söderström, M.3
  • 36
    • 0028913137 scopus 로고
    • Increased mRNA expression of IL-10 in mononuclear cells in multiple sclerosis and optic neuritis
    • Navikas V, Link J, Palasik W et al. Increased mRNA expression of IL-10 in mononuclear cells in multiple sclerosis and optic neuritis. Scand J Immunol 1995;41:171-8.
    • (1995) Scand J Immunol , vol.41 , pp. 171-178
    • Navikas, V.1    Link, J.2    Palasik, W.3
  • 37
    • 13344278688 scopus 로고    scopus 로고
    • Augmented expression of tumour necrosis factor-α and lymphotoxin mRNA in mononuclear cells in multiple sclerosis and optic neuritis
    • Navikas V, He B, Link J et al. Augmented expression of tumour necrosis factor-α and lymphotoxin mRNA in mononuclear cells in multiple sclerosis and optic neuritis. Brain 1996;119:213-23.
    • (1996) Brain , vol.119 , pp. 213-223
    • Navikas, V.1    He, B.2    Link, J.3
  • 38
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995;13:251-76.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 39
    • 0028956699 scopus 로고
    • Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction
    • Shu U, Kinuwa M, Wu CY et al. Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction. Eur J Immunol 1995;25:1125-8.
    • (1995) Eur J Immunol , vol.25 , pp. 1125-1128
    • Shu, U.1    Kinuwa, M.2    Wu, C.Y.3
  • 41
    • 0027264849 scopus 로고
    • Interleukin-12 is required for the T-cell independent induction of interferon-γ by an intracellular parasite and induces resistance in T-deficient hosts
    • Guzzinneli RT, Hieny S, Wynn TA, Wolf S, Sher A. Interleukin-12 is required for the T-cell independent induction of interferon-γ by an intracellular parasite and induces resistance in T-deficient hosts. Proc Natl Acad Sci USA 1993;90:6115-9.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6115-6119
    • Guzzinneli, R.T.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 42
    • 0027933432 scopus 로고
    • Cooperation of natural cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells
    • Aste-Amezaga M, D'Andrea A, Kubin M, Trinchieri G. Cooperation of natural cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells. Cell Immunol 1994;156:480-92.
    • (1994) Cell Immunol , vol.156 , pp. 480-492
    • Aste-Amezaga, M.1    D'Andrea, A.2    Kubin, M.3    Trinchieri, G.4
  • 43
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
    • Panitch HS, Hirsh L, Schindler J, Johnson KP. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987;37:1097-102.
    • (1987) Neurology , vol.37 , pp. 1097-1102
    • Panitch, H.S.1    Hirsh, L.2    Schindler, J.3    Johnson, K.P.4
  • 44
    • 0029410743 scopus 로고
    • Interferon-γ-induced oligodendrocyte cell death: Implications for the pathogenesis of multiple sclerosis
    • Vartanian T, Li Y, Zhao M, Stetanson K. Interferon-γ-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol Med 1995;1:732-43.
    • (1995) Mol Med , vol.1 , pp. 732-743
    • Vartanian, T.1    Li, Y.2    Zhao, M.3    Stetanson, K.4
  • 46
    • 0027234230 scopus 로고
    • Cytotoxicity of T cells for cerebral endothelium in multiple sclerosis
    • Tsukada N, Matsuda M, Miyagi K, Yanagisawa N. Cytotoxicity of T cells for cerebral endothelium in multiple sclerosis. J Neurol Sci 1993;117:140-7.
    • (1993) J Neurol Sci , vol.117 , pp. 140-147
    • Tsukada, N.1    Matsuda, M.2    Miyagi, K.3    Yanagisawa, N.4
  • 47
    • 0027265549 scopus 로고
    • Modulation of perform and granzyme messenger RNA expression in human natural killer cells
    • Salcedo TW, Azzoni L, Wolf SF, Perussia B. Modulation of perform and granzyme messenger RNA expression in human natural killer cells. J Immunol 1993;151:2511-20.
    • (1993) J Immunol , vol.151 , pp. 2511-2520
    • Salcedo, T.W.1    Azzoni, L.2    Wolf, S.F.3    Perussia, B.4
  • 48
    • 0028987310 scopus 로고
    • TGF-β suppresses autoantigen-induced expression of proinflammatory cytokines but not of IL-10 in multiple sclerosis and myasthenia gravis
    • Link J, He B, Navikas V et al. TGF-β suppresses autoantigen-induced expression of proinflammatory cytokines but not of IL-10 in multiple sclerosis and myasthenia gravis. J Neuroimmunol 1995;58:21-35.
    • (1995) J Neuroimmunol , vol.58 , pp. 21-35
    • Link, J.1    He, B.2    Navikas, V.3
  • 49
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merill JE, Ignarro LJ, Shermann MP, Melinek J, Lane TE. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 1993;151:2132-41.
    • (1993) J Immunol , vol.151 , pp. 2132-2141
    • Merill, J.E.1    Ignarro, L.J.2    Shermann, M.P.3    Melinek, J.4    Lane, T.E.5


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