Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling

Annual Review of Biochemistry

Volumn 76, Issue , 2007, Pages 481-511

  Conti, Marco ^a   Beavo, Joseph ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Gpcrs; Pdes; Second messengers

Indexed keywords

BACTERIAL ENZYME; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ENZYME VARIANT; FUNGAL ENZYME; HOLOENZYME; I KAPPA B; METAL ION; MUTANT PROTEIN; PHOSPHODIESTERASE I; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PROTEIN 14 3 3; PROTOZOAL PROTEIN; RETINA S ANTIGEN; SILDENAFIL; TADALAFIL; VARDENAFIL; CYCLIC NUCLEOTIDE; G PROTEIN COUPLED RECEPTOR; I KAPPA B KINASE; ION; ISOENZYME; METAL; PHOSPHODIESTERASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ASTHMA; CELL COMPARTMENTALIZATION; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CRYSTAL STRUCTURE; DICTYOSTELIUM; DIMERIZATION; DRUG DETERMINATION; DRUG IDENTIFICATION; ENDOCRINE DISEASE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ERECTILE DYSFUNCTION; FEEDBACK SYSTEM; GENETIC ASSOCIATION; GENETIC DISORDER; HOMEOSTASIS; HUMAN; INTERMITTENT CLAUDICATION; LIGAND BINDING; MACROMOLECULE; METAZOON; MOLECULAR RECOGNITION; MULTIGENE FAMILY; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; OSCILLATION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROKARYOTIC CELL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PULMONARY HYPERTENSION; RETINA DEGENERATION; REVIEW; SIGNAL TRANSDUCTION; STROKE; YEAST; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; PHYLOGENY; PHYSIOLOGY; PROTEIN CONFORMATION;

EUKARYOTA; PROKARYOTA;

14-3-3 PROTEINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ARRESTINS; CATALYTIC DOMAIN; EVOLUTION, MOLECULAR; HOMEOSTASIS; HUMANS; I-KAPPA B KINASE; IONS; ISOENZYMES; METALS; MODELS, MOLECULAR; MULTIGENE FAMILY; NUCLEOTIDES, CYCLIC; PHOSPHORIC DIESTER HYDROLASES; PHYLOGENY; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 34447265905     PISSN: 00664154     EISSN: 00664154     Source Type: Book Series    
DOI: 10.1146/annurev.biochem.76.060305.150444     Document Type: Review

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