In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors

Journal of General Physiology

Volumn 118, Issue 1, 2001, Pages 63-77

  Rich, Thomas C ^a   Tse, Tonia E ^a   Rohan, Joyce G ^a   Schaack, Jerome ^a   Karpen, Jeffrey W ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Adenylyl cyclase; Biosensors; Calcium influx; G protein signaling; GH4 pituitary cells

Indexed keywords

ADENYLATE CYCLASE; CALMODULIN; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; DIFFUSION; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; SECOND MESSENGER; SENSITIVITY AND SPECIFICITY; SENSOR; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; CELL MEMBRANE; CYCLIC AMP; ELECTROPHYSIOLOGY; GTP-BINDING PROTEIN REGULATORS; ION CHANNEL GATING; NUCLEOTIDES, CYCLIC; PHOSPHORIC DIESTER HYDROLASES; PLASMIDS; POINT MUTATION; RATS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0034942107     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.118.1.63     Document Type: Article

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