Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells

British Journal of Pharmacology

Volumn 142, Issue 2, 2004, Pages 339-351

  Shepherd, Malcolm C ^a,c   Baillie, George S ^a   Stirling, David I ^b   Houslay, Miles D ^a,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b CELGENE CORPORATION   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

ERK; Macrophage; Monocyte; PDE4 cAMP specific phosphodiesterase; Rolipram; U937

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CILOSTAMIDE; CYCLIC AMP PHOSPHODIESTERASE; CYCLIC AMP PHOSPHODIESTERASE 4A10; CYCLIC AMP PHOSPHODIESTERASE 4A4; CYCLIC AMP PHOSPHODIESTERASE 4B2; CYCLIC AMP PHOSPHODIESTERASE 4D3; CYCLIC AMP PHOSPHODIESTERASE 4D5; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; ROLIPRAM; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CELL; CELL DIFFERENTIATION; CELL STRAIN U937; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PURIFICATION; STIMULATION; UPREGULATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; CELL DIFFERENTIATION; HUMANS; ISOENZYMES; MACROPHAGES; MONOCYTES; U937 CELLS;

EID: 2942552151     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705770     Document Type: Article

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