Induction of specific phosphodiesterase isoforms by constitutive activation of the cAMP pathway in autonomous thyroid adenomas

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 8, 2000, Pages 2872-2878

  Persani, Luca ^a,e   Lania, Andrea ^b   Alberti, Luisella ^a   Romoli, Roberto ^b   Mantovani, Giovanna ^b   Filetti, Sebastiano ^c   Spada, Anna ^b   Conti, Marco ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d STANFORD UNIVERSITY   (United States)

^e ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; ISOBUTYLMETHYLXANTHINE; PHOSPHODIESTERASE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE IV; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; THYROTROPIN RECEPTOR;

ARTICLE; CELL DIFFERENTIATION; CELL DIVISION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SYNTHESIS; FEEDBACK SYSTEM; GENE MUTATION; HUMAN; HUMAN TISSUE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEADY STATE; THYROID ADENOMA; THYROID CELL;

ADENOMA; CYCLIC AMP; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; ISOENZYMES; MUTATION; PHOSPHORIC DIESTER HYDROLASES; RECEPTORS, THYROTROPIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; THYROID NEOPLASMS; TRANSCRIPTION, GENETIC;

EID: 0034458407     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.85.8.2872     Document Type: Article

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