-
1
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
Beavo, J. A. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol. Rev. 75, 725-748 (1995).
-
(1995)
Physiol. Rev.
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
2
-
-
0034009080
-
Regulation of cAMP and EGMP signaling: New phosphodiesterases and new functions
-
Soderling, S. H. & Beavo, J. A. Regulation of cAMP and EGMP signaling: new phosphodiesterases and new functions. Curr. Opin. Cell Biol, 12, 174-179 (2000).
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 174-179
-
-
Soderling, S.H.1
Beavo, J.A.2
-
3
-
-
0033553509
-
Cyclic GMP phosphodiesterase-5: Target of sildenafil
-
Corbin, J. D. & Francis, S. H. Cyclic GMP phosphodiesterase-5: target of sildenafil. J. Biol. Chem. 274, 13729-13732 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13729-13732
-
-
Corbin, J.D.1
Francis, S.H.2
-
4
-
-
0036717930
-
Phosphodiestease 5 inhibitors: Current status and potential application
-
Rotella, D. P. Phosphodiestease 5 inhibitors: current status and potential application. Nature Rev. Drug Discov. 1, 674-682 (2002).
-
(2002)
Nature Rev. Drug Discov.
, vol.1
, pp. 674-682
-
-
Rotella, D.P.1
-
5
-
-
0029009878
-
Recent progress in understanding the hormonal regulation of phosphodiesterases
-
Conti, M., Nemoz, G., Sette, C. & Vicini, E. Recent progress in understanding the hormonal regulation of phosphodiesterases. Endocr. Rev. 16, 370-389 (1995).
-
(1995)
Endocr. Rev.
, vol.16
, pp. 370-389
-
-
Conti, M.1
Nemoz, G.2
Sette, C.3
Vicini, E.4
-
7
-
-
0036134416
-
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling
-
Mechats, C., Andersen, C. B., Filopanti, M., Jin, S. L. & Conti, M. Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling. Trends Endocr. Met. 13, 29-35 (2002).
-
(2002)
Trends Endocr. Met.
, vol.13
, pp. 29-35
-
-
Mechats, C.1
Andersen, C.B.2
Filopanti, M.3
Jin, S.L.4
Conti, M.5
-
8
-
-
0034625541
-
Atomic structure of PDE4: Insights into phosphodiesterase mechanism and specificity
-
Xu, R. X. et al. Atomic structure of PDE4: Insights into phosphodiesterase mechanism and specificity. Science 288, 1822-1825 (2000).
-
(2000)
Science
, vol.288
, pp. 1822-1825
-
-
Xu, R.X.1
-
9
-
-
0037163858
-
Crystal structure of phosphodiesterase 4D and inhibitor complex
-
Lee, M. E., Markowitz, J., Lee, J.-O. & Lee, H. Crystal structure of phosphodiesterase 4D and inhibitor complex. FEBS Lett. 530, 53-58 (2002).
-
(2002)
FEBS Lett.
, vol.530
, pp. 53-58
-
-
Lee, M.E.1
Markowitz, J.2
Lee, J.-O.3
Lee, H.4
-
10
-
-
0037415730
-
PDE 5 is converted to an activated state upon cGMP binding to the GAF A domain
-
Rybalkin, S. D., Rybalkina, I. G., Shimizu-Albergine, M., Tang, X. B. & Beavo, J. A. PDE5 is converted to an activated state upon cGMP binding to the GAF A domain. EMBO J. 23, 469-478 (2003).
-
(2003)
EMBO J.
, vol.23
, pp. 469-478
-
-
Rybalkin, S.D.1
Rybalkina, I.G.2
Shimizu-Albergine, M.3
Tang, X.B.4
Beavo, J.A.5
-
11
-
-
0036332629
-
Pharmacology of phosphodiesterase-5 inhibitors
-
Corbin, J. D. & Francis, S. H. Pharmacology of phosphodiesterase-5 inhibitors. Int. J. Clin. Pract. 56, 453-459 (2002).
-
(2002)
Int. J. Clin. Pract.
, vol.56
, pp. 453-459
-
-
Corbin, J.D.1
Francis, S.H.2
-
12
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK 2 complex
-
Jeffrey, P. D. et al. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376, 313-320 (1995).
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
-
13
-
-
0028978670
-
Crystal structure of a TFIIB-TBP-TATA-element ternary complex
-
Nikolov, D. B. et al. Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature 377, 119-128 (1995).
-
(1995)
Nature
, vol.377
, pp. 119-128
-
-
Nikolov, D.B.1
-
14
-
-
0032513145
-
Potential roles of conserved amino acids in the catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5)
-
Turko, I. V., Francis, S. H. & Corbin, J. D. Potential roles of conserved amino acids in the catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5). J. Biol. Chem. 273, 6460-6466 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6460-6466
-
-
Turko, I.V.1
Francis, S.H.2
Corbin, J.D.3
-
15
-
-
0036797810
-
Expert opinion: Vardenafil
-
Young, J. M. Expert opinion: Vardenafil. Expert Opin. Invest. Drugs 11, 1487-1496 (2002).
-
(2002)
Expert Opin. Invest. Drugs
, vol.11
, pp. 1487-1496
-
-
Young, J.M.1
-
16
-
-
0004001340
-
-
(eds Schudt, C., Dent, G. & Rabe, K. F.) (Academic, New) York
-
Sekhar, K. R., Grondin, P., Francis, S. H. & Corbin, J. D. Phosphodiesterase Inhibitors (eds Schudt, C., Dent, G. & Rabe, K. F.) 135-146 (Academic, New York, 1996).
-
(1996)
Phosphodiesterase Inhibitors
, pp. 135-146
-
-
Sekhar, K.R.1
Grondin, P.2
Francis, S.H.3
Corbin, J.D.4
-
17
-
-
0031045585
-
Preparation of selenomethionyl proteins for phase determination
-
Doublie, S. Preparation of selenomethionyl proteins for phase determination. Methods Enzymol. 276, 523-529 (1997).
-
(1997)
Methods Enzymol.
, vol.276
, pp. 523-529
-
-
Doublie, S.1
-
18
-
-
0042931751
-
-
Indole derivatives as PDE5-inhibitors. PCT Int. Appl. WO0236593 A1 (2002)
-
Orme, M. W., Sawyer, J. S. & Schultze, L. M. Indole derivatives as PDE5-inhibitors. PCT Int. Appl. WO0236593 A1 (2002).
-
-
-
Orme, M.W.1
Sawyer, J.S.2
Schultze, L.M.3
-
19
-
-
0031059866
-
Processing of x-ray diffraction data collected in oscillation mode
-
Otwinowski, M. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods. Enzymol. 276, 307-326 (1997).
-
(1997)
Methods. Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, M.1
Minor, W.2
-
21
-
-
0033896691
-
Maximum likelihood density modification
-
Terwilliger, T. C. Maximum likelihood density modification. Acta Crystallogr. D 56, 965-972 (2000).
-
(2000)
Acta Crystallogr. D
, vol.56
, pp. 965-972
-
-
Terwilliger, T.C.1
-
22
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones, T., Zou, J.-Y., Cowan, S. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47,110-119 (1991).
-
(1991)
Acta Crystallogr. A
, vol.47
, pp. 110-119
-
-
Jones, T.1
Zou, J.-Y.2
Cowan, S.3
Kjeldgaard, M.4
-
23
-
-
3543012707
-
Crystallography & N.M.R. system: A new software suite for macromolecular structure determination
-
Brûnger, A. T. et al. Crystallography & N.M.R. system: a new software suite for macromolecular structure determination. Acta Crystallogr. D 54, 905-921 (1998).
-
(1998)
Acta Crystallogr. D
, vol.54
, pp. 905-921
-
-
Brûnger, A.T.1
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