cA glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

Molecular Cell

Volumn 15, Issue 2, 2004, Pages 279-286

  Zhang, Kam Y J ^c   Card, Graeme L ^c   Suzuki, Yoshihisa ^c   Artis, D Richard ^c   Fong, Daniel ^c   Gillette, Sam ^c   Hsieh, Davin ^c   Neiman, Joshua ^c   West, Brian L ^c   Zhang, Chao ^c   Milburn, Michael V ^c   Kim, Sung Hou ^a   Schlessinger, Joseph ^b   Bollag, Gideon ^a  

^a PLEXXIKON INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; CYCLIC AMP; GLUTAMINE; GUANOSINE PHOSPHATE; NUCLEOTIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE V; PURINE; 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CGMP BINDING, CGMP SPECIFIC 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CYCLIC GMP; CYCLIC GMP PHOSPHODIESTERASE;

ANALYTIC METHOD; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; HUMAN; METABOLISM; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; CYCLIC GMP; GLUTAMINE; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 4344676386     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2004.07.005     Document Type: Article

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