Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

Circulation Research

Volumn 95, Issue 1, 2004, Pages 67-75

  Mongillo, Marco ^a,b,c   McSorley, Theresa ^d   Evellin, Sandrine ^b   Sood, Arvind ^d   Lissandron, Valentina ^a,b,c   Terrin, Anna ^a   Huston, Elaine ^d   Hannawacker, Annette ^e   Lohse, Martin J ^e   Pozzan, Tullio ^b,c   Houslay, Miles D ^d   Zaccolo, Manuela ^a,b  

^a DULBECCO TELETHON INSTITUTE   (Italy)

^b VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

^e UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

CAMP; Fluorescence resonance energy transfer imaging; Heart signaling; Phosphodiesterase

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; EXCITATION CONTRACTION COUPLING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADRENERGIC ALPHA-AGONISTS; ANIMALS; ANIMALS, NEWBORN; CYCLIC AMP; FLUORESCENCE RESONANCE ENERGY TRANSFER; MYOCYTES, CARDIAC; NOREPINEPHRINE; PHOSPHODIESTERASE INHIBITORS; RATS;

EID: 3142723295     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000134629.84732.11     Document Type: Article

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