Phosphorylation of phosphodiesterase-5 is promoted by a conformational change induced by sildenafil, vardenafil, or tadalafil

Frontiers in Bioscience

Volumn 12, Issue 5, 2007, Pages 1899-1910

  Bessay, Emmanuel P ^a   Zoraghi, Roya ^a   Blount, Mitsi A ^a   Grimes, Kennard A ^a   Beasley, Alfreda ^a   Francis, Sharron H ^a   Corbin, Jackie D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cGMP; Conformation; Dephosphorylation; PDE5 inhibitors; Phosphodiesterase 5; Phosphoprotein phosphatase; Phosphorylation; PP1; PP2A; Protein kinase A; Protein kinase G; Sildenafil; Tadalafil; Vardenafil

Indexed keywords

EID: 34249781979     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2196     Document Type: Article

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