Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2

Journal of Biological Chemistry

Volumn 278, Issue 35, 2003, Pages 33351-33363

  Bolger, Graeme B ^a,c   Peden, Alexander H ^b   Steele, Michael R ^a   MacKenzie, Carolynn ^b   McEwan, David G ^b   Wallace, Derek A ^b   Huston, Elaine ^b   Baillie, George S ^b   Houslay, Miles D ^b  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BRAIN; CELLS; ENZYMES;

ENZYMATIC ACTIVITY;

BIOCHEMISTRY;

ARGININE; CYCLIC AMP PHOSPHODIESTERASE; IMMUNOPHILIN; ISOENZYME; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV A5; PROTEIN AIPL1; PROTEIN FKBP51; PROTEIN FKBP52; PROTEIN KINASE; PROTEIN XAP2; ROLIPRAM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; IC 50; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; TRINUCLEOTIDE REPEAT; TWO HYBRID SYSTEM; YEAST;

1-METHYL-3-ISOBUTYLXANTHINE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ALANINE; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; COS CELLS; CYCLIC AMP; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FORSKOLIN; GENE DELETION; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOBLOTTING; INHIBITORY CONCENTRATION 50; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RATS; RECOMBINANT FUSION PROTEINS; ROLIPRAM; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 0041856176     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303269200     Document Type: Article

References (59)

1. Beavo, J. A., and Brunton, L. L. (2002) Nat. Rev. Mol. Cell. Biol. 3, 710-718
2. Houslay, M. D., Sullivan, M., and Bolger, G. B. (1998) Adv. Pharmacol. 44, 225-342
3. Conti, M., Richter, W., Mehats, C., Livera, G., Park, J. Y., and Jin, C. (2003) J. Biol. Chem. 278, 5493-5496
4. Bolger, G., Michaeli, T., Martins, T., St. John, T., Steiner, B., Rodgers, L., Riggs, M., Wigler, M., and Ferguson, K. (1993) Mol. Cell. Biol. 13, 6558-6571
5. Bolger, G. B., Rodgers, L., and Riggs, M. (1994) Gene (Amst.) 149, 237-244
6. Bolger, G. B., McPhee, I., and Houslay, M. D. (1996) J. Biol. Chem. 271, 1065-1071
7. McPhee, I., Cochran, S., and Houslay, M. D. (2001) Cell Signal. 13, 911-918
8. Beard, M. B., Huston, E., Campbell, L., Gall, I., McPhee, I., Yarwood, S., Scotland, G., and Houslay, M. D. (2002) Cell Signal. 14, 453-465
9. Huston, E., Beard, M., McCallum, F., Pyne, N. J., Vandenabeele, P., Scotland, G., and Houslay, M. D. (2000) J. Biol. Chem. 275, 28063-28074
10. O'Connell, J. C., McCallum, J. F., McPhee, I., Wakefield, J., Houslay, E. S., Wishart, W., Bolger, G., Frame, M., and Houslay, M. D. (1996) Biochem. J. 318, 255-262
11. Ma, Q., and Whitlock, J. P. J. (1997) J. Biol. Chem. 272, 8878-8884
12. Carver, L. A., and Bradfield, C. A. (1997) J. Biol. Chem. 272, 11452-11456
13. Meyer, B. K., Pray-Grant, M. G., Vanden, H. J., and Perdew, G. H. (1998) Mol. Cell. Biol. 18, 978-988
14. Marks, A. R. (1996) Physiol. Rev. 76, 631-649
15. Carver, L. A., LaPres, J. J., Jain, S., Dunham, E. E., and Bradfield, C. A. (1998) J. Biol. Chem. 273, 33580-33587
16. Kuzhandaivelu, N., Cong, Y. S., Inouye, C., Yang, W. M., and Seto, E. (1996) Nucleic Acids Res. 24, 4741-4750
17. Kazlauskas, A., Poellinger, L., and Pongratz, I. (2002) J. Biol. Chem. 277, 11795-11801
18. Sohocki, M. M., Bowne, S. J., Sullivan, L. S., Blackshaw, S., Cepko, C. L., Payne, A. M., Bhattacharya, S. S., Khaliq, S., Qasim, M. S., Birch, D. G., Harrison, W. R., Elder, F. F., Heckenlively, J. R., and Daiger, S. P. (2000) Nat. Genet. 24, 79-83
19. Smith, D. F., Albers, M. W., Schreiber, S. L., Leach, K. L., and Deibel, M. R., Jr. (1993) J. Biol. Chem. 268, 24270-24273
20. Bolger, G. B. (1998) Methods Mol. Biol. 88, 101-131
21. Yarwood, S. J., Steele, M. R., Scotland, G., Houslay, M. D., and Bolger, G. B. (1999) J. Biol. Chem. 274, 14909-14917
22. McPhee, I., Yarwood, S. J., Scotland, G., Huston, E., Beard, M. B., Ross, A. H., Houslay, E. S., and Houslay, M. D. (1999) J. Biol. Chem. 274, 11796-11810
23. McPhee, I., Pooley, L., Lobban, M., Bolger, G., and Houslay, M. D. (1995) Biochem. J. 310, 965-974
24. Harlow, E., and Lane, D. P. (1990) Antibodies: A Laboratory Manual, 1st Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
25. Shakur, Y., Wilson, M., Pooley, L., Lobban, M., Griffiths, S. L., Campbell, A. M., Beattie, J., Daly, C., and Houslay, M. D. (1995) Biochem. J. 306, 801-809
26. Marchmont, R. J., and Houslay, M. D. (1980) Biochem. J. 187, 381-392
27. MacKenzie, S. J., Baillie, G. S., McPhee, I., MacKenzie, C., Seamons, R., McSorley, T., Millen, J., Beard, M. B., Van Heeke, G., and Houslay, M. D. (2002) Br. J. Pharmacol. 136, 421-433
28. Shepard, M., McSorley, T., Olsen, A. E., Johnston, L. A., Thomson, N. C., Baillie, G. S., Houslay, M. D., and Bolger, G. B. (2003) Biochem. J. 370, 429-438
29. Sikorski, R. S., Boguski, M. S., Goebl, M., and Hieter, P. (1990) Cell 60, 307-317
30. Uzawa, S., Samejima, I., Hirano, T., Tanaka, K., and Yanagida, M. (1990) Cell 62, 913-925
31. Das, A. K., Cohen, P. W., and Barford, D. (1998) EMBO J. 17, 1192-1199
32. Scheufler, C., Brinker, A., Bourenkov, G., Pegoraro, S., Moroder, L., Bartunik, H., Hartl, F. U., and Moarefi, I. (2000) Cell 101, 199-210
33. Taylor, P., Dornan, J., Carrello, A., Minchin, R. F., Ratajczak, T., and Walkinshaw, M. D. (2001) Structure 9, 431-438
34. Russell, L. C. Whitt, S. R., Chen, M. S., and Chinkers, M. (1999) J. Biol. Chem. 274, 20060-20063
35. Bell, D. R., and Poland, A. (2000) J. Biol. Chem. 275, 36407-36414
36. Young, J. C., Obermann, W. M., and Hartl, F. U. (1998) J. Biol. Chem. 273, 18007-18010
37. Liu, F. H., Wu, S. J., Hu, S. M., Hsiao, C. D., and Wang, C. (1999) J. Biol. Chem. 274, 34425-34432
38. Carrello, A., Ingley, E., Minchin, R. F., Tsai, S., and Ratajczak, T. (1999) J. Biol. Chem. 274, 2682-2689
39. Beard, M. B., Olsen, A. E., Jones, R. E., Erdogan, S., Houslay, M. D., and Bolger, G. B. (2000) J. Biol. Chem. 275, 10349-10358
40. Richter, W., and Conti, M. (2002) J. Biol. Chem. 277, 40212-40221
41. Rena, G., Begg, F., Ross, A., MacKenzie, C., McPhee, I., Campbell, L., Huston, E., Sullivan, M., and Houslay, M. D. (2001) Mol. Pharmacol. 59, 996-1011
42. Harding, M. W., Galat, A., Uehling, D. E., and Schreiber, S. L. (1989) Nature 341, 758-760
43. Galat, A., Lane, W. S., Standaert, R. F., and Schreiber, S. L. (1992) Biochem. istry 31, 2427-2434
44. Jin, Y. J., Burakoff, S. J., and Bierer, B. E. (1992) J. Biol. Chem. 267, 10942-10945
45. Sette, C., Vicini, E., and Conti, M. (1994) J. Biol. Chem. 269, 18271-18274
46. Sette, C., Iona, S., and Conti, M. (1994) J. Biol. Chem. 269, 9245-9252
47. Sette, C., and Conti, M. (1996) J. Biol. Chem. 271, 16526-16534
48. Lim, J., Pahlke, G., and Conti, M. (1999) J. Biol. Chem. 274, 19677-19685
49. Hoffmann, R., Wilkinson, I. R., McCallum, J. F., Engels, P., and Houslay, M. D. (1998) Biochem. J. 333, 139-149
50. MacKenzie, S. J., Baillie, G. S., McPhee, I., Bolger, G. B., and Houslay, M. D. (2000) J. Biol. Chem. 275, 16609-16617
51. Dodge, K. L., Khouangsathiene, S., Kapiloff, M. S., Mouton, R., Hill, E. V., Houslay, M. D., Langeberg, L. K., and Scott, J. D. (2001) EMBO J. 20, 1921-1930
52. Shakur, Y., Pryde, J. G., and Houslay, M. D. (1993) Biochem. J. 292, 677-686
53. Torphy, T. J., and Page, C. (2000) Trends Pharmacol. Sci. 21, 157-159
54. Giembycz, M. A. (2000) Drugs 59, 193-212
55. Xu, R. X., Hassell, A. M., Vanderwall, D., Lambert, M. H., Holmes, W. D., Luther, M. A., Rocque, W. J., Milburn, M. V., Zhao, Y., Ke, H., and Nolte, R. T. (2000) Science 288, 1822-1825
56. Souness, J. E., and Rao, S. (1997) Cell Signal. 9, 227-236
57. Chen, Y. G., Liu, F., and Massague, J. (1997) EMBO J. 16, 3866-3876
58. Huse, M., Muir, T. W., Xu, L., Chen, Y. G., Kuriyan, J., and Massague, J. (2001) Mol. Cell 8, 671-682
59. Gaburjakova, M., Gaburjakova, J., Reiken, S., Huang, F., Marx, S. O., Rosemblit, N., and Marks, A. R. (2001) J. Biol. Chem. 276, 16931-16935