-
1
-
-
0033561637
-
IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells
-
AHMAD, F., GAO, G., LING MEI, W., LANDSTROM, T.R., DEGERMAN, E., PIERCE, J.H. & MANGANIELLO, V.C. (1999). IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells. J. Immunol., 162, 4864-4875.
-
(1999)
J. Immunol.
, vol.162
, pp. 4864-4875
-
-
Ahmad, F.1
Gao, G.2
Ling Mei, W.3
Landstrom, T.R.4
Degerman, E.5
Pierce, J.H.6
Manganiello, V.C.7
-
2
-
-
0025871767
-
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
-
ALVAREZ, E., NORTHWOOD, I.C., GONZALEZ, F.A., LATOUR, D.A., SETH, A., ABATE, C. CURRAN, T. & DAVIS, R.J. (1991). Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. J. Biol. Chem., 266, 15277-15285.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15277-15285
-
-
Alvarez, E.1
Northwood, I.C.2
Gonzalez, F.A.3
Latour, D.A.4
Seth, A.5
Abate, C.6
Curran, T.7
Davis, R.J.8
-
3
-
-
0028839684
-
Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3
-
ALVAREZ, R., SETTE, C., YANG, D., EGLEN, R.M., WILHELM, R., SHELTON, E.R. & CONTI, M. (1995). Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3. Mol. Pharmacol., 48, 616-622.
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 616-622
-
-
Alvarez, R.1
Sette, C.2
Yang, D.3
Eglen, R.M.4
Wilhelm, R.5
Shelton, E.R.6
Conti, M.7
-
4
-
-
0034616226
-
UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase (PDE4) family form a discrete module via electrostatic interactions
-
BEARD, M.B., OLSEN, A.E., JONES, R.E., ERDOGAN, S., HOUSLAY, M.D. & BOLGER, G.B. (2000). UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase (PDE4) family form a discrete module via electrostatic interactions. J. Biol. Chem., 275, 10349-10358.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10349-10358
-
-
Beard, M.B.1
Olsen, A.E.2
Jones, R.E.3
Erdogan, S.4
Houslay, M.D.5
Bolger, G.B.6
-
5
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
BEAVO, J.A. (1995). Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol. Rev., 75, 725-748.
-
(1995)
Physiol. Rev.
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
6
-
-
0033552609
-
A novel regulatory mechanism of MAP kinase activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase
-
BLANCO-APARICIO, C., TORRES, J. & PULIDO, R. (1999). A novel regulatory mechanism of MAP kinase activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase. J. Cell Biol., 147, 1129-1135.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1129-1135
-
-
Blanco-Aparicio, C.1
Torres, J.2
Pulido, R.3
-
7
-
-
0028358806
-
Diversity in function and regulation of MAP kinase pathways
-
BLUMER, K.J. & JOHNSON, G.L. (1994). Diversity in function and regulation of MAP kinase pathways. Trends Biochem. Sci., 19, 236-240.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 236-240
-
-
Blumer, K.J.1
Johnson, G.L.2
-
8
-
-
0028574848
-
Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes
-
BOLGER, G. (1994). Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes. Cell. Signal., 6, 851-859.
-
(1994)
Cell. Signal.
, vol.6
, pp. 851-859
-
-
Bolger, G.1
-
9
-
-
0027454556
-
A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs
-
BOLGER, G., MICHAELI, T. MARTINS, T. ST. JOHN, T., STEINER, B., RODGERS, L., RIGGS, M., WIGLER, M. & FERGUSON, K. (1993). A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol. Cell. Biol., 13, 6558-6571.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6558-6571
-
-
Bolger, G.1
Michaeli, T.2
Martins, T.3
St. John, T.4
Steiner, B.5
Rodgers, L.6
Riggs, M.7
Wigler, M.8
Ferguson, K.9
-
10
-
-
0030665303
-
Characterisation of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene
-
BOLGER, G.B., ERDOGAN, S., JONES, R.E., LOUGHNEY, K., SCOTLAND, G., HOFFMAN, R., WILKINSON, I., FARRELL, C. & HOUSLAY, M.D. (1997). Characterisation of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene. Biochem. J., 328, 539-548.
-
(1997)
Biochem. J.
, vol.328
, pp. 539-548
-
-
Bolger, G.B.1
Erdogan, S.2
Jones, R.E.3
Loughney, K.4
Scotland, G.5
Hoffman, R.6
Wilkinson, I.7
Farrell, C.8
Houslay, M.D.9
-
11
-
-
0030047931
-
Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts: Characterization of a novel tissue-specific isoform, RNPDE4A8
-
BOLGER, G.B., MCPHEE, I. & HOUSLAY, M.D. (1996). Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts: characterization of a novel tissue-specific isoform, RNPDE4A8. J. Biol. Chem., 271, 1065-1071.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1065-1071
-
-
Bolger, G.B.1
Mcphee, I.2
Houslay, M.D.3
-
12
-
-
0017184389
-
Protein determination in biological samples
-
BRADFORD, M. (1976). Protein determination in biological samples. Anal. Biochem., 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.1
-
13
-
-
0027501802
-
ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor
-
ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. EMBO J., 12, 4211-4220.
-
(1993)
EMBO J.
, vol.12
, pp. 4211-4220
-
-
Burgering, B.M.1
Pronk, G.J.2
Van Weeren, P.C.3
Chardin, P.4
Bos, J.L.5
-
14
-
-
0029031827
-
Phosphodiesterase IV inhibitors: Structural diversity and therapeutic potential in asthma
-
CAVALLA, D. & FRITH, R. (1995). Phosphodiesterase IV inhibitors: structural diversity and therapeutic potential in asthma. Curr. Opin. Med. Chem., 2, 561-572.
-
(1995)
Curr. Opin. Med. Chem.
, vol.2
, pp. 561-572
-
-
Cavalla, D.1
Frith, R.2
-
15
-
-
0033021636
-
AKAPs: Prom structure to function
-
COLLEDGE, M. & SCOTT, J.D. (1999). AKAPs: prom structure to function. Trends Cell Biol., 9, 216-221.
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 216-221
-
-
Colledge, M.1
Scott, J.D.2
-
16
-
-
0032605044
-
The molecular biology of cyclic nucleotide phosphodiesterases
-
CONTI, M. & JIN, S.L.C. (1999). The molecular biology of cyclic nucleotide phosphodiesterases. Prog. Nucleic Acid Res., 63, 1-38.
-
(1999)
Prog. Nucleic Acid Res.
, vol.63
, pp. 1-38
-
-
Conti, M.1
Jin, S.L.C.2
-
17
-
-
0027716596
-
Inhibition by cAMP of ras-dependent activation of raf
-
COOK, S.J. & MCCORMICK, F. (1993). Inhibition by cAMP of ras-dependent activation of raf. Science, 262, 1069-1072.
-
(1993)
Science
, vol.262
, pp. 1069-1072
-
-
Cook, S.J.1
Mccormick, F.2
-
18
-
-
0029040541
-
Selective phosphodiesterase inhibitors in the therapy of asthma
-
DENT, G. & GIEMBYCZ, M.A. (1995). Selective phosphodiesterase inhibitors in the therapy of asthma. Clin. Immunother., 3, 423-437.
-
(1995)
Clin. Immunother.
, vol.3
, pp. 423-437
-
-
Dent, G.1
Giembycz, M.A.2
-
19
-
-
0030248274
-
Phosphodiesterase 4 and tolerance to beta2-adrenoceptor agonists in asthma
-
GIEMBYCZ, M.A. (1996). Phosphodiesterase 4 and tolerance to beta2-adrenoceptor agonists in asthma. Trends Pharmacol. Sci., 17, 331-336.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 331-336
-
-
Giembycz, M.A.1
-
20
-
-
0027374550
-
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells
-
GRAVES, L.M., BORNFELDT, K.E., RAINES, E.W., POTTS, B.C., MACDONALD, S.G., ROSS, R. & KREBS, E.G. (1993). Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc. Natl. Acad. Sci. U.S.A., 90, 10300-10304.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 10300-10304
-
-
Graves, L.M.1
Bornfeldt, K.E.2
Raines, E.W.3
Potts, B.C.4
Macdonald, S.G.5
Ross, R.6
Krebs, E.G.7
-
21
-
-
0028124505
-
Mechanism of inhibition of Raf-1 by protein kinase A
-
HAFNER, S., ADLER, H.S. & MISCHAK, H. (1994). Mechanism of inhibition of Raf-1 by protein kinase A. Mol. Cell Biol., 14, 6696-6703.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 6696-6703
-
-
Hafner, S.1
Adler, H.S.2
Mischak, H.3
-
22
-
-
0030985901
-
Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes
-
HERRERA-VELIT, P., KNUTSON, K.L. & REINER, N.E. (1997). Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes. J. Biol. Chem., 272, 16445-16452.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16445-16452
-
-
Herrera-Velit, P.1
Knutson, K.L.2
Reiner, N.E.3
-
23
-
-
0030070975
-
lyn and phosphatidylinositol 3-kinase in human monocytes
-
lyn and phosphatidylinositol 3-kinase in human monocytes. J. Immunol., 156, 1157-1165.
-
(1996)
J. Immunol.
, vol.156
, pp. 1157-1165
-
-
Herrera-Velit, P.R.N.E.1
-
24
-
-
0020609348
-
Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes
-
HEYWORTH, C.M. & HOUSLAY, M.D. (1983). Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes. Biochem. J., 214, 93-98.
-
(1983)
Biochem. J.
, vol.214
, pp. 93-98
-
-
Heyworth, C.M.1
Houslay, M.D.2
-
26
-
-
0032127768
-
cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: Generation of a molecular model
-
HOFFMANN, R., WILKINSON, I.R., MCCALLUM, J.F., ENGELS, P. & HOUSLAY, M.D. (1998). cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model. Biochem. J., 333, 139-149.
-
(1998)
Biochem. J.
, vol.333
, pp. 139-149
-
-
Hoffmann, R.1
Wilkinson, I.R.2
Mccallum, J.F.3
Engels, P.4
Houslay, M.D.5
-
27
-
-
0030974622
-
Tailoring cAMP signalling responses through isoform multiplicity
-
HOUSLAY, M.D. & MILLIGAN, G. (1997). Tailoring cAMP signalling responses through isoform multiplicity. Trends Biochem. Sci., 22, 217-224.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 217-224
-
-
Houslay, M.D.1
Milligan, G.2
-
28
-
-
0031601339
-
The multi-enzyme PDE4 cyclic AMP specific phosphodiesterase family: Intracellular targeting, regulation and selective inhibition by compounds exerting anti-inflammatory and anti-depressant actions
-
HOUSLAY, M.D., SULLIVAN, M. & BOLGER, G.B. (1998). The multi-enzyme PDE4 cyclic AMP specific phosphodiesterase family: intracellular targeting, regulation and selective inhibition by compounds exerting anti-inflammatory and anti-depressant actions. Adv. Pharmacol., 44, 225-342.
-
(1998)
Adv. Pharmacol.
, vol.44
, pp. 225-342
-
-
Houslay, M.D.1
Sullivan, M.2
Bolger, G.B.3
-
29
-
-
0030697068
-
Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cyclic AMP specific phosphodiesterase, HSPDE4B3
-
HUSTON, E., LUMB, S., RUSSELL, A., CATTERALL, C., ROSS, A.H., STEELE, M.R., BOLGER, G.B., PERRY, M., OWENS, R. & HOUSLAY, M.D. (1997). Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cyclic AMP specific phosphodiesterase, HSPDE4B3. Biochem. J., 328, 549-558.
-
(1997)
Biochem. J.
, vol.328
, pp. 549-558
-
-
Huston, E.1
Lumb, S.2
Russell, A.3
Catterall, C.4
Ross, A.H.5
Steele, M.R.6
Bolger, G.B.7
Perry, M.8
Owens, R.9
Houslay, M.D.10
-
30
-
-
0029857245
-
The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species which exhibit distinct kinetics of inhibition by the anti-depressant rolipram
-
HUSTON, E., POOLEY, L., JULIEN, J., SCOTLAND, G., MCPHEE, I., SULLIVAN, M., BOLGER, G. & HOUSLAY, M.D. (1996). The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species which exhibit distinct kinetics of inhibition by the anti-depressant rolipram. J. Biol. Chem., 271, 31334-31344.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31334-31344
-
-
Huston, E.1
Pooley, L.2
Julien, J.3
Scotland, G.4
Mcphee, I.5
Sullivan, M.6
Bolger, G.7
Houslay, M.D.8
-
31
-
-
0014949207
-
Cleavage of structural proteins during assembly of the head of bacteriophage T4
-
LAEMMLI, U.K. (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 222, 680-682.
-
(1970)
Nature
, vol.222
, pp. 680-682
-
-
Laemmli, U.K.1
-
32
-
-
0029820823
-
Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase
-
LENHARD, J.M., KASSEL, D.B., ROCQUE, W.J., HAMACHER, L., HOLMES, W.D., PATEL, I., HOFFMAN, C. & LUTHER, M. (1996). Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase. Biochem. J., 316, 751-758.
-
(1996)
Biochem. J.
, vol.316
, pp. 751-758
-
-
Lenhard, J.M.1
Kassel, D.B.2
Rocque, W.J.3
Hamacher, L.4
Holmes, W.D.5
Patel, I.6
Hoffman, C.7
Luther, M.8
-
33
-
-
0033537946
-
Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases: A potential mechanism allowing for the coordinated regulation of PDE4D activity and targeting
-
LIU, H. & MAURICE, D.H. (1999). Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases: a potential mechanism allowing for the coordinated regulation of PDE4D activity and targeting. J. Biol. Chem., 274, 10557-10565.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10557-10565
-
-
Liu, H.1
Maurice, D.H.2
-
34
-
-
0034595707
-
ERK2 MAP kinase binding, phosphorylation and regulation of PDE4D cAMP specific phosphodiesterases: The involvement of C-terminal docking sites and N-terminal UCR regions
-
MACKENZIE, S.J., BAILLIE, G.S., MCPHEE, I., BOLGER, G.B. & HOUSLAY, M.D. (2000). ERK2 MAP kinase binding, phosphorylation and regulation of PDE4D cAMP specific phosphodiesterases: the involvement of C-terminal docking sites and N-terminal UCR regions. J. Biol. Chem., 275, 16609-16617.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16609-16617
-
-
Mackenzie, S.J.1
Baillie, G.S.2
Mcphee, I.3
Bolger, G.B.4
Houslay, M.D.5
-
35
-
-
0034655448
-
The action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of CREB and p38 MAP kinase in U937 monocytic cells
-
MACKENZIE, S.J. & HOUSLAY, M.D. (2000). The action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of CREB and p38 MAP kinase in U937 monocytic cells. Biochem. J., 347, 571-578.
-
(2000)
Biochem. J.
, vol.347
, pp. 571-578
-
-
Mackenzie, S.J.1
Houslay, M.D.2
-
36
-
-
0032584089
-
Stimulation of p70S6 kinase via a growth hormone controlled PI-3 kinase pathway leads to the activation of a PDE4 cAMP specific phosphodiesterases in 3T3-F442A preadipocytes
-
MACKENZIE, S.J., YARWOOD, S.J., PEDEN, A.H., BOLGER, G.B., VERNON, R.J. & HOUSLAY, M.D. (1998). Stimulation of p70S6 kinase via a growth hormone controlled PI-3 kinase pathway leads to the activation of a PDE4 cAMP specific phosphodiesterases in 3T3-F442A preadipocytes. Proc. Natl. Acad. Sci. U.S.A., 95, 3549-3554.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 3549-3554
-
-
Mackenzie, S.J.1
Yarwood, S.J.2
Peden, A.H.3
Bolger, G.B.4
Vernon, R.J.5
Houslay, M.D.6
-
37
-
-
0029146718
-
Diversity in cyclic nucleotide phosphodiesterase isoenzyme families
-
MANGANIELLO, V.C., MURATA, T., TAIRA, M., BELFRAGE, P. & DEGERMAN, E. (1995). Diversity in cyclic nucleotide phosphodiesterase isoenzyme families. Arch. Biochem. Biophys., 322, 1-13.
-
(1995)
Arch. Biochem. Biophys.
, vol.322
, pp. 1-13
-
-
Manganiello, V.C.1
Murata, T.2
Taira, M.3
Belfrage, P.4
Degerman, E.5
-
38
-
-
0032747518
-
Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B
-
MANNING, C.D., BURMAN, M., CHRISTENSEN, S.B., CIESLINSKI, L.B., ESSAYAN, D.M., GROUS, D., TORPHY, T.J. & BARNETTE, M.S. (1999). Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B. Br. J. Pharmacol., 128, 1393-1398.
-
(1999)
Br. J. Pharmacol.
, vol.128
, pp. 1393-1398
-
-
Manning, C.D.1
Burman, M.2
Christensen, S.B.3
Cieslinski, L.B.4
Essayan, D.M.5
Grous, D.6
Torphy, T.J.7
Barnette, M.S.8
-
39
-
-
0019167160
-
Insulin controls the cyclic AMP-dependent phosphorylation of integral and peripheral proteins associated with the rat liver plasma membrane
-
MARCHMONT, R.J. & HOUSLAY, M.D. (1980). Insulin controls the cyclic AMP-dependent phosphorylation of integral and peripheral proteins associated with the rat liver plasma membrane. FEBS Lett., 118, 18-24.
-
(1980)
FEBS Lett.
, vol.118
, pp. 18-24
-
-
Marchmont, R.J.1
Houslay, M.D.2
-
40
-
-
0033597139
-
Association with the src family tyrosyl kinase lyn triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B: Consequences for rolipram inhibition
-
MCPHEE, I., YARWOOD, S.J., HUSTON, E., SCOTLAND, G., BEARD, M.B., ROSS, A.H., HOUSLAY, E.S. & HOUSLAY, M.D. (1999). Association with the src family tyrosyl kinase lyn triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B: consequences for rolipram inhibition. J. Biol. Chem., 274, 11796-11810.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11796-11810
-
-
Mcphee, I.1
Yarwood, S.J.2
Huston, E.3
Scotland, G.4
Beard, M.B.5
Ross, A.H.6
Houslay, E.S.7
Houslay, M.D.8
-
41
-
-
0028314313
-
Inhibitors of cyclic nucleotide phosphodiesterase isoenzymes-their potential utility in the therapy of asthma
-
NICHOLSON, C.D. & SHAHID, M. (1994). Inhibitors of cyclic nucleotide phosphodiesterase isoenzymes-their potential utility in the therapy of asthma. Pulm. Pharmacol., 7, 1-17.
-
(1994)
Pulm. Pharmacol.
, vol.7
, pp. 1-17
-
-
Nicholson, C.D.1
Shahid, M.2
-
42
-
-
0030817316
-
Molecular cloning and expression of a human phosphodiesterase 4C
-
OWENS, R.J., LUMB, S., REES-MILTON, K., RUSSELL, A., BALDOCK, D., LANG, V., CRABBE, T., BALLESTEROS, M. & PERRY, M.J. (1997). Molecular cloning and expression of a human phosphodiesterase 4C. Cell. Signal., 9, 575-585.
-
(1997)
Cell. Signal.
, vol.9
, pp. 575-585
-
-
Owens, R.J.1
Lumb, S.2
Rees-Milton, K.3
Russell, A.4
Baldock, D.5
Lang, V.6
Crabbe, T.7
Ballesteros, M.8
Perry, M.J.9
-
44
-
-
0033193930
-
Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase
-
SAXENA, M., WILLIAMS, S., TASKEN, K. & MUSTELIN, T. (1999). Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase. Nature Cell. Biol., 1, 305-311.
-
(1999)
Nature Cell. Biol.
, vol.1
, pp. 305-311
-
-
Saxena, M.1
Williams, S.2
Tasken, K.3
Mustelin, T.4
-
45
-
-
0032973433
-
Selective phosphodiesterase inhibitors for the treatment of bronchial asthma and chronic obstructive pulmonary disease
-
SCHMIDT, D., DENT, G. & RABE, K.F. (1999). Selective phosphodiesterase inhibitors for the treatment of bronchial asthma and chronic obstructive pulmonary disease. Clin. Exp. Allergy, 29 (Suppl. 2): 99-109.
-
(1999)
Clin. Exp. Allergy
, vol.29
, Issue.2 SUPPL.
, pp. 99-109
-
-
Schmidt, D.1
Dent, G.2
Rabe, K.F.3
-
46
-
-
0029165312
-
PDE isoenzymes as targets for anti-asthma drugs
-
SCHUDT, C., TENOR, H. & HATZELMANN, A. (1995). PDE isoenzymes as targets for anti-asthma drugs. Eur. Respir. J., 8, 1179-1183.
-
(1995)
Eur. Respir. J.
, vol.8
, pp. 1179-1183
-
-
Schudt, C.1
Tenor, H.2
Hatzelmann, A.3
-
47
-
-
0030006920
-
Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase: Involvement of serine 54 in the enzyme activation
-
SETTE, C. & CONTI, M. (1996). Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase: involvement of serine 54 in the enzyme activation. J. Biol. Chem., 271, 16526-16534.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16526-16534
-
-
Sette, C.1
Conti, M.2
-
48
-
-
0028243837
-
The short-term activation of a rolipram-sensitive, cAMP-specific phosphodiesterase by thyroid-stimulating hormone in thyroid FRTL-5 cells is mediated by a cAMP-dependent phosphorylation
-
SETTE, C., IONA, S. & CONTI, M. (1994). The short-term activation of a rolipram-sensitive, cAMP-specific phosphodiesterase by thyroid-stimulating hormone in thyroid FRTL-5 cells is mediated by a cAMP-dependent phosphorylation. J. Biol. Chem., 269, 9245-9252.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 9245-9252
-
-
Sette, C.1
Iona, S.2
Conti, M.3
-
49
-
-
0027485031
-
Increasing cAMP attenuates activation of mitogen-activated protein kinase
-
SEVETSON, B.R., KONG, X. & LAWRENCE, JR., J.C. (1993). Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. U.S.A., 90, 10305-10309.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 10305-10309
-
-
Sevetson, B.R.1
Kong, X.2
Lawrence Jr., J.C.3
-
50
-
-
0032493818
-
2-adrenoreceptor desensitization
-
2-adrenoreceptor desensitization. J. Biol. Chem., 273, 20575-20588.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20575-20588
-
-
Seybold, J.1
Newton, R.2
Wright, L.3
Finney, P.A.4
Suttorp, N.5
Barnes, P.J.6
Adcock, I.M.7
Giembycz, M.A.8
-
51
-
-
0028897835
-
Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum
-
SHAKUR, Y., WILSON, M., POOLEY, L., LOBBAN, M., GRIFFITHS, S.L., CAMPBELL, A.M., BEATTIE, J., DALY, C. & HOUSLAY, M.D. (1995). Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum. Biochem. J., 306, 801-809.
-
(1995)
Biochem. J.
, vol.306
, pp. 801-809
-
-
Shakur, Y.1
Wilson, M.2
Pooley, L.3
Lobban, M.4
Griffiths, S.L.5
Campbell, A.M.6
Beattie, J.7
Daly, C.8
Houslay, M.D.9
-
52
-
-
0030925148
-
Proposal for pharmacologically distinct conformers of PDE4
-
SOUNESS, J.E. & RAO, S. (1997). Proposal for pharmacologically distinct conformers of PDE4. Cell. Signal., 9, 227-236.
-
(1997)
Cell. Signal.
, vol.9
, pp. 227-236
-
-
Souness, J.E.1
Rao, S.2
-
53
-
-
0031601540
-
The role of phosphodiesterase enzymes in allergy and asthma
-
SPINA, D., LANDELLS, L.J. & PAGE, C.P. (1998). The role of phosphodiesterase enzymes in allergy and asthma. Adv. Pharmacol., 44, 33-89.
-
(1998)
Adv. Pharmacol.
, vol.44
, pp. 33-89
-
-
Spina, D.1
Landells, L.J.2
Page, C.P.3
-
54
-
-
0032886033
-
Genomic organisation of the human cyclic AMP specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between the genes for RAB3A and JUND
-
SULLIVAN, M., OLSEN, A.S. & HOUSLAY, M.D. (1999). Genomic organisation of the human cyclic AMP specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between the genes for RAB3A and JUND. Cell. Signal., 11, 735-742.
-
(1999)
Cell. Signal.
, vol.11
, pp. 735-742
-
-
Sullivan, M.1
Olsen, A.S.2
Houslay, M.D.3
-
55
-
-
0032143286
-
Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2
-
SULLIVAN, M., RENA, G., BEGG, F., GORDON, L., OLSEN, A.S. & HOUSLAY, M.D. (1998). Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2. Biochem. J., 333, 693-703.
-
(1998)
Biochem. J.
, vol.333
, pp. 693-703
-
-
Sullivan, M.1
Rena, G.2
Begg, F.3
Gordon, L.4
Olsen, A.S.5
Houslay, M.D.6
-
56
-
-
0030984966
-
Phosphodiesterase (PDE)4 inhibitors: Anti-inflammatory drugs of the future?
-
TEIXEIRA, M.M., GRISTWOOD, R.W., COOPER, N. & HELLEWELL, P.G. (1997). Phosphodiesterase (PDE)4 inhibitors: anti-inflammatory drugs of the future? Trends Pharmacol. Sci., 18, 164-170.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 164-170
-
-
Teixeira, M.M.1
Gristwood, R.W.2
Cooper, N.3
Hellewell, P.G.4
-
57
-
-
0015231739
-
Multiple cyclic nucleotide phosphodiesterase activities from rat brain
-
THOMPSON, W.J. & APPLEMAN, M.M. (1971). Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry, 10, 311-316.
-
(1971)
Biochemistry
, vol.10
, pp. 311-316
-
-
Thompson, W.J.1
Appleman, M.M.2
-
58
-
-
0033567291
-
The stress-activated protein kinase pathways
-
TIBBLES, L.A. & WOODGETT, J.R. (1999). The stress-activated protein kinase pathways. Cell. Mol. Life Sci., 55, 1230-1254.
-
(1999)
Cell. Mol. Life Sci.
, vol.55
, pp. 1230-1254
-
-
Tibbles, L.A.1
Woodgett, J.R.2
-
59
-
-
0031914520
-
Phosphodiesterase isozymes: Molecular targets for novel antiasthma agents
-
TORPHY, T.J. (1998). Phosphodiesterase isozymes: molecular targets for novel antiasthma agents. Am. J. Respir. Crit. Care Med., 157, 351-370.
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.157
, pp. 351-370
-
-
Torphy, T.J.1
-
60
-
-
0033106501
-
Ariflo™ (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: From concept to clinic
-
TORPHY, T.J., BARNETTE, M.S., UNDERWOOD, D.C., GRISWOLD, D.E., CHRISTENSEN, S.B., MURDOCH, R.D., NIEMAN, R.B. & COMPTON, C.H. (1999). Ariflo™ (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic. Pulm. Pharmacol. Ther., 12, 131-135.
-
(1999)
Pulm. Pharmacol. Ther.
, vol.12
, pp. 131-135
-
-
Torphy, T.J.1
Barnette, M.S.2
Underwood, D.C.3
Griswold, D.E.4
Christensen, S.B.5
Murdoch, R.D.6
Nieman, R.B.7
Compton, C.H.8
-
61
-
-
0033033913
-
Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophils
-
WANG, P., WU, P., OHLETH, K.M., EGAN, R.W. & BILLAH, M.M. (1999). Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophils. Mol. Pharmacol., 56, 170-174.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 170-174
-
-
Wang, P.1
Wu, P.2
Ohleth, K.M.3
Egan, R.W.4
Billah, M.M.5
-
62
-
-
0032619557
-
The complexities of CD28 and CTLA-4 signalling: P13K and beyond
-
WARD, S.G. (1999). The complexities of CD28 and CTLA-4 signalling: P13K and beyond. Arch. Immunol. Ther. Exp. (Warsz.), 47, 69-75.
-
(1999)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.47
, pp. 69-75
-
-
Ward, S.G.1
-
63
-
-
0027772672
-
Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
-
WU, J., DENT, P., JELINEK, T., WOLFMAN, A., WEBER, M.J. & STURGILL, T.W. (1993). Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science, 262, 1065-1069.
-
(1993)
Science
, vol.262
, pp. 1065-1069
-
-
Wu, J.1
Dent, P.2
Jelinek, T.3
Wolfman, A.4
Weber, M.J.5
Sturgill, T.W.6
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