-
1
-
-
10744230726
-
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility
-
Alloatti G., Levi R., Malan D., Del Sorbo L., Bosco O., Barberis L., Marcantoni A., Bedendi I., Penna C., Azzolino O., et al. Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility. Cardiovasc. Res. 60:2003;242-249
-
(2003)
Cardiovasc. Res.
, vol.60
, pp. 242-249
-
-
Alloatti, G.1
Levi, R.2
Malan, D.3
Del Sorbo, L.4
Bosco, O.5
Barberis, L.6
Marcantoni, A.7
Bedendi, I.8
Penna, C.9
Azzolino, O.10
-
2
-
-
0035941418
-
Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a
-
Antos C.L., Frey N., Marx S.O., Reiken S., Gaburjakova M., Richardson J.A., Marks A.R., Olson E.N. Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a. Circ. Res. 89:2001;997-1004
-
(2001)
Circ. Res.
, vol.89
, pp. 997-1004
-
-
Antos, C.L.1
Frey, N.2
Marx, S.O.3
Reiken, S.4
Gaburjakova, M.5
Richardson, J.A.6
Marks, A.R.7
Olson, E.N.8
-
3
-
-
0032699668
-
Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse
-
Asai K., Yang G.P., Geng Y.J., Takagi G., Bishop S., Ishikawa Y., Shannon R.P., Wagner T.E., Vatner D.E., Homcy C.J., Vatner S.F. Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse. J. Clin. Invest. 104:1999;551-558
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 551-558
-
-
Asai, K.1
Yang, G.P.2
Geng, Y.J.3
Takagi, G.4
Bishop, S.5
Ishikawa, Y.6
Shannon, R.P.7
Wagner, T.E.8
Vatner, D.E.9
Homcy, C.J.10
Vatner, S.F.11
-
4
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
Beavo J.A. Cyclic nucleotide phosphodiesterases. functional implications of multiple isoforms Physiol. Rev. 75:1995;725-748
-
(1995)
Physiol. Rev.
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
5
-
-
0032500730
-
Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK
-
Bondeva T., Pirola L., Bulgarelli-Leva G., Rubio I., Wetzker R., Wymann M.P. Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK. Science. 282:1998;293-296
-
(1998)
Science
, vol.282
, pp. 293-296
-
-
Bondeva, T.1
Pirola, L.2
Bulgarelli-Leva, G.3
Rubio, I.4
Wetzker, R.5
Wymann, M.P.6
-
6
-
-
0037236642
-
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
-
Brancaccio M., Fratta L., Notte A., Hirsch E., Poulet R., Guazzone S., De Acetis M., Vecchione C., Marino G., Altruda F., et al. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat. Med. 9:2003;68-75
-
(2003)
Nat. Med.
, vol.9
, pp. 68-75
-
-
Brancaccio, M.1
Fratta, L.2
Notte, A.3
Hirsch, E.4
Poulet, R.5
Guazzone, S.6
De Acetis, M.7
Vecchione, C.8
Marino, G.9
Altruda, F.10
-
7
-
-
0037027480
-
Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure
-
Brede M., Wiesmann F., Jahns R., Hadamek K., Arnolt C., Neubauer S., Lohse M.J., Hein L. Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure. Circulation. 106:2002;2491-2496
-
(2002)
Circulation
, vol.106
, pp. 2491-2496
-
-
Brede, M.1
Wiesmann, F.2
Jahns, R.3
Hadamek, K.4
Arnolt, C.5
Neubauer, S.6
Lohse, M.J.7
Hein, L.8
-
8
-
-
0036843158
-
Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death
-
Bueno O.F., Molkentin J.D. Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. Circ. Res. 91:2002;776-781
-
(2002)
Circ. Res.
, vol.91
, pp. 776-781
-
-
Bueno, O.F.1
Molkentin, J.D.2
-
9
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley L.C. The phosphoinositide 3-kinase pathway. Science. 296:2002;1655-1657
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
10
-
-
18644372367
-
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
-
Crackower M.A., Oudit G.Y., Kozieradzki I., Sarao R., Sun H., Sasaki T., Hirsch E., Suzuki A., Shioi T., Irie-Sasaki J., et al. Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell. 110:2002;737-749
-
(2002)
Cell
, vol.110
, pp. 737-749
-
-
Crackower, M.A.1
Oudit, G.Y.2
Kozieradzki, I.3
Sarao, R.4
Sun, H.5
Sasaki, T.6
Hirsch, E.7
Suzuki, A.8
Shioi, T.9
Irie-Sasaki, J.10
-
11
-
-
0033535942
-
Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
-
Engelhardt S., Hein L., Wiesmann F., Lohse M.J. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc. Natl. Acad. Sci. USA. 96:1999;7059-7064
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7059-7064
-
-
Engelhardt, S.1
Hein, L.2
Wiesmann, F.3
Lohse, M.J.4
-
12
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
Hirsch E., Katanaev V.L., Garlanda C., Azzolino O., Pirola L., Silengo L., Sozzani S., Mantovani A., Altruda F., Wymann M.P. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science. 287:2000;1049-1053
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
Sozzani, S.7
Mantovani, A.8
Altruda, F.9
Wymann, M.P.10
-
13
-
-
0029912925
-
Adverse effects of chronic endogenous sympathetic drive induced by cardiac GS alpha overexpression
-
Iwase M., Bishop S.P., Uechi M., Vatner D.E., Shannon R.P., Kudej R.K., Wight D.C., Wagner T.E., Ishikawa Y., Homcy C.J., Vatner S.F. Adverse effects of chronic endogenous sympathetic drive induced by cardiac GS alpha overexpression. Circ. Res. 78:1996;517-524
-
(1996)
Circ. Res.
, vol.78
, pp. 517-524
-
-
Iwase, M.1
Bishop, S.P.2
Uechi, M.3
Vatner, D.E.4
Shannon, R.P.5
Kudej, R.K.6
Wight, D.C.7
Wagner, T.E.8
Ishikawa, Y.9
Homcy, C.J.10
Vatner, S.F.11
-
14
-
-
0032766006
-
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt
-
Kitamura T., Kitamura Y., Kuroda S., Hino Y., Ando M., Kotani K., Konishi H., Matsuzaki H., Kikkawa U., Ogawa W., Kasuga M. Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt. Mol. Cell. Biol. 19:1999;6286-6296
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6286-6296
-
-
Kitamura, T.1
Kitamura, Y.2
Kuroda, S.3
Hino, Y.4
Ando, M.5
Kotani, K.6
Konishi, H.7
Matsuzaki, H.8
Kikkawa, U.9
Ogawa, W.10
Kasuga, M.11
-
15
-
-
0035834071
-
The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
-
Liao P., Georgakopoulos D., Kovacs A., Zheng M., Lerner D., Pu H., Saffitz J., Chien K., Xiao R.P., Kass D.A., Wang Y. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy. Proc. Natl. Acad. Sci. USA. 98:2001;12283-12288
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12283-12288
-
-
Liao, P.1
Georgakopoulos, D.2
Kovacs, A.3
Zheng, M.4
Lerner, D.5
Pu, H.6
Saffitz, J.7
Chien, K.8
Xiao, R.P.9
Kass, D.A.10
Wang, Y.11
-
16
-
-
0036950082
-
Gene expression in fibroblasts and fibrosis: Involvement in cardiac hypertrophy
-
Manabe I., Shindo T., Nagai R. Gene expression in fibroblasts and fibrosis. involvement in cardiac hypertrophy Circ. Res. 91:2002;1103-1113
-
(2002)
Circ. Res.
, vol.91
, pp. 1103-1113
-
-
Manabe, I.1
Shindo, T.2
Nagai, R.3
-
17
-
-
0037151104
-
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
-
Matsui T., Li L., Wu J.C., Cook S.A., Nagoshi T., Picard M.H., Liao R., Rosenzweig A. Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J. Biol. Chem. 277:2002;22896-22901
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22896-22901
-
-
Matsui, T.1
Li, L.2
Wu, J.C.3
Cook, S.A.4
Nagoshi, T.5
Picard, M.H.6
Liao, R.7
Rosenzweig, A.8
-
18
-
-
0036278525
-
PDE3 cyclic nucleotide phosphodiesterases and the compartmentation of cyclic nucleotide-mediated signalling in cardiac myocytes
-
Movsesian M.A. PDE3 cyclic nucleotide phosphodiesterases and the compartmentation of cyclic nucleotide-mediated signalling in cardiac myocytes. Basic Res. Cardiol. Suppl. 97:2002;I83-I90
-
(2002)
Basic Res. Cardiol. Suppl.
, vol.97
-
-
Movsesian, M.A.1
-
19
-
-
0034681226
-
Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy
-
Naga Prasad S.V., Esposito G., Mao L., Koch W.J., Rockman H.A. Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J. Biol. Chem. 275:2000;4693-4698
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4693-4698
-
-
Naga Prasad, S.V.1
Esposito, G.2
Mao, L.3
Koch, W.J.4
Rockman, H.A.5
-
20
-
-
0036327388
-
Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex
-
Naga Prasad S.V., Laporte S.A., Chamberlain D., Caron M.G., Barak L., Rockman H.A. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. J. Cell Biol. 158:2002;563-575
-
(2002)
J. Cell Biol.
, vol.158
, pp. 563-575
-
-
Naga Prasad, S.V.1
Laporte, S.A.2
Chamberlain, D.3
Caron, M.G.4
Barak, L.5
Rockman, H.A.6
-
21
-
-
85047693926
-
Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure
-
Nienaber J.J., Tachibana H., Naga Prasad S.V., Esposito G., Wu D., Mao L., Rockman H.A. Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure. J. Clin. Invest. 112:2003;1067-1079
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1067-1079
-
-
Nienaber, J.J.1
Tachibana, H.2
Naga Prasad, S.V.3
Esposito, G.4
Wu, D.5
Mao, L.6
Rockman, H.A.7
-
22
-
-
0242381308
-
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure
-
Published online September 8, 2003.
-
Oudit G.Y., Crackower M.A., Eriksson U., Sarao R., Kozieradzki I., Sasaki T., Irie-Sasaki J., Gidrewicz D., Rybin V.O., Wada T., et al. Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. Circulation. 108:2003;2147-2152. Published online September 8, 2003.
-
(2003)
Circulation
, vol.108
, pp. 2147-2152
-
-
Oudit, G.Y.1
Crackower, M.A.2
Eriksson, U.3
Sarao, R.4
Kozieradzki, I.5
Sasaki, T.6
Irie-Sasaki, J.7
Gidrewicz, D.8
Rybin, V.O.9
Wada, T.10
-
23
-
-
0038015697
-
Role of phosphoinositide 3-kinase in cardiac function and heart failure
-
Prasad S.V., Perrino C., Rockman H.A. Role of phosphoinositide 3-kinase in cardiac function and heart failure. Trends Cardiovasc. Med. 13:2003;206-212
-
(2003)
Trends Cardiovasc. Med.
, vol.13
, pp. 206-212
-
-
Prasad, S.V.1
Perrino, C.2
Rockman, H.A.3
-
24
-
-
0034857217
-
Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy
-
Rapacciuolo A., Esposito G., Caron K., Mao L., Thomas S.A., Rockman H.A. Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy. J. Am. Coll. Cardiol. 38:2001;876-882
-
(2001)
J. Am. Coll. Cardiol.
, vol.38
, pp. 876-882
-
-
Rapacciuolo, A.1
Esposito, G.2
Caron, K.3
Mao, L.4
Thomas, S.A.5
Rockman, H.A.6
-
25
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
Rockman H.A., Koch W.J., Lefkowitz R.J. Seven-transmembrane-spanning receptors and heart function. Nature. 415:2002;206-212
-
(2002)
Nature
, vol.415
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
26
-
-
0034616384
-
Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor
-
Rondinone C.M., Carvalho E., Rahn T., Manganiello V.C., Degerman E., Smith U.P. Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor. J. Biol. Chem. 275:2000;10093-10098
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10093-10098
-
-
Rondinone, C.M.1
Carvalho, E.2
Rahn, T.3
Manganiello, V.C.4
Degerman, E.5
Smith, U.P.6
-
27
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
Shioi T., Kang P.M., Douglas P.S., Hampe J., Yballe C.M., Lawitts J., Cantley L.C., Izumo S. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 19:2000;2537-2548
-
(2000)
EMBO J.
, vol.19
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
Hampe, J.4
Yballe, C.M.5
Lawitts, J.6
Cantley, L.C.7
Izumo, S.8
-
28
-
-
0030887632
-
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
Stephens L.R., Eguinoa A., Erdjument-Bromage H., Lui M., Cooke F., Coadwell J., Smrcka A.S., Thelen M., Cadwallader K., Tempst P., Hawkins P.T. The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Cell. 89:1997;105-114
-
(1997)
Cell
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
Lui, M.4
Cooke, F.5
Coadwell, J.6
Smrcka, A.S.7
Thelen, M.8
Cadwallader, K.9
Tempst, P.10
Hawkins, P.T.11
-
29
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov B., Volinia S., Hanck T., Rubio I., Loubtchenkov M., Malek D., Stoyanova S., Vanhaesebroeck B., Dhand R., Nurnberg B., et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science. 269:1995;690-693
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nurnberg, B.10
-
30
-
-
0030920653
-
Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: Structure-activity analysis and interactions with wortmannin
-
Stoyanova S., Bulgarelli-Leva G., Kirsch C., Hanck T., Klinger R., Wetzker R., Wymann M.P. Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma. structure-activity analysis and interactions with wortmannin Biochem. J. 324:1997;489-495
-
(1997)
Biochem. J.
, vol.324
, pp. 489-495
-
-
Stoyanova, S.1
Bulgarelli-Leva, G.2
Kirsch, C.3
Hanck, T.4
Klinger, R.5
Wetzker, R.6
Wymann, M.P.7
-
31
-
-
0015239529
-
Characterization of cyclic nucleotide phosphodiesterases of rat tissues
-
Thompson W.J., Appleman M.M. Characterization of cyclic nucleotide phosphodiesterases of rat tissues. J. Biol. Chem. 246:1971;3145-3150
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 3145-3150
-
-
Thompson, W.J.1
Appleman, M.M.2
-
32
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck B., Leevers S.J., Ahmadi K., Timms J., Katso R., Driscoll P.C., Woscholski R., Parker P.J., Waterfield M.D. Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70:2001;535-602
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
33
-
-
0037323892
-
Phosphoinositide 3-kinase gamma: A key modulator in inflammation and allergy
-
a
-
Wymann M.P., Bjorklof K., Calvez R., Finan P., Thomast M., Trifilieff A., Barbier M., Altruda F., Hirsch E., Laffargue M. Phosphoinositide 3-kinase gamma. a key modulator in inflammation and allergy Biochem. Soc. Trans. 31:2003;275-280. a
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 275-280
-
-
Wymann, M.P.1
Bjorklof, K.2
Calvez, R.3
Finan, P.4
Thomast, M.5
Trifilieff, A.6
Barbier, M.7
Altruda, F.8
Hirsch, E.9
Laffargue, M.10
-
35
-
-
0034105968
-
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice
-
Zhang D., Gaussin V., Taffet G.E., Belaguli N.S., Yamada M., Schwartz R.J., Michael L.H., Overbeek P.A., Schneider M.D. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat. Med. 6:2000;556-563
-
(2000)
Nat. Med.
, vol.6
, pp. 556-563
-
-
Zhang, D.1
Gaussin, V.2
Taffet, G.E.3
Belaguli, N.S.4
Yamada, M.5
Schwartz, R.J.6
Michael, L.H.7
Overbeek, P.A.8
Schneider, M.D.9
-
36
-
-
85047687695
-
The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis
-
Zhang S., Weinheimer C., Courtois M., Kovacs A., Zhang C.E., Cheng A.M., Wang Y., Muslin A.J. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. J. Clin. Invest. 111:2003;833-841
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 833-841
-
-
Zhang, S.1
Weinheimer, C.2
Courtois, M.3
Kovacs, A.4
Zhang, C.E.5
Cheng, A.M.6
Wang, Y.7
Muslin, A.J.8
|