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Volumn 123, Issue 12, 2001, Pages 2835-2838
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First computational evidence for a catalytic bridging hydroxide ion in a phosphodiesterase active site
a,b c |
Author keywords
[No Author keywords available]
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Indexed keywords
CATALYTIC BRIDGING;
CATALYST ACTIVITY;
CRYSTAL STRUCTURE;
DEGRADATION;
DRUG THERAPY;
IONS;
ENZYMES;
HYDROXIDE;
PHOSPHODIESTERASE;
ARTICLE;
CATALYSIS;
CRYSTAL STRUCTURE;
ENZYME ACTIVE SITE;
ENZYME ACTIVITY;
ENZYME STRUCTURE;
LIGAND BINDING;
MATHEMATICAL COMPUTING;
QUANTUM MECHANICS;
STRUCTURE ANALYSIS;
X RAY CRYSTALLOGRAPHY;
BINDING SITES;
CATALYTIC DOMAIN;
HUMANS;
HYDROXIDES;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
PHOSPHORIC DIESTER HYDROLASES;
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EID: 0034801310
PISSN: 00027863
EISSN: None
Source Type: Journal
DOI: 10.1021/ja005529a Document Type: Article |
Times cited : (66)
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References (27)
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