The oligomerization state determines regulatory properties and inhibitor sensitivity of type 4 cAMP-specific phosphodiesterases

Journal of Biological Chemistry

Volumn 279, Issue 29, 2004, Pages 30338-30348

  Richter, Wito ^a   Conti, Marco ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CATALYSIS; DIMERIZATION; ENZYME INHIBITION; MONOMERS; PROTEINS;

OLIGOMERIZATION; PHOSPHATIDIC ACID; PHOSPHORYLATION; STRUCTURAL ELEMENT;

OLIGOMERS;

CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHATIDIC ACID; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; DIMERIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBUNIT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CATALYSIS; CATALYTIC DOMAIN; CENTRIFUGATION, DENSITY GRADIENT; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; COS CELLS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; DIMERIZATION; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OPEN READING FRAMES; PHOSPHATIDIC ACIDS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; ROLIPRAM; TRANSFECTION;

ANIMALIA;

EID: 3142776354     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312687200     Document Type: Article

References (37)

1. Francis, S. H., Turko, I. V., and Corbin, J. D. (2001) Prog. Nucleic Acids Res. Mol. Biol. 65, 1-52
2. Yan, C., Zhao, A. Z., Bentley, J. K., Loughney, K., Ferguson, K., and Beavo, J. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9677-9681
3. Kincaid, R. L., Stith-Coleman, I. E., and Vaughan, M. (1985) J. Biol. Chem. 260, 9009-9015
4. Wada, H., Osborne, J. C., Jr., and Manganiello, V. C. (1987) J. Biol. Chem. 262, 5139-5144
5. Shakur, Y., Holst, L. S., Landstrom, T. R., Movsesian, M., Degerman, E., and Manganiello, V. (2001) Prog. Nucleic Acids Res. Mol. Biol. 66, 241-277
6. Sette, C., and Conti, M. (1996) J. Biol. Chem. 271, 16526-16534
7. MacKenzie, S. J., Baillie, G. S., McPhee, I., MacKenzie, C., Seamons, R., McSorley, T., Millen, J., Beard, M. B., van Heeke, G., and Houslay, M. D. (2002) Br. J. Pharmacol. 136, 421-433
8. Grange, M., Sette, C., Cuomo, M., Conti, M., Lagarde, M., Prigent, A. F., and Nemoz, G. (2000) J. Biol. Chem. 275, 33379-33387
9. Rybalkin, S. D., Rybalkina, I. G., Shimizu-Albergine, M., Tang, X. B., and Beavo, J. A. (2003) EMBO J. 22, 469-478
10. Martinez, S. E., Wu, A. Y., Glavas, N. A., Tang, X. B., Turley, S., Hol, W. G., and Beavo, J. A. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13260-13265
11. Yamamoto, T., Manganiello, V. C., and Vaughan, M. (1983) J. Biol. Chem. 258, 12526-12533
12. Kenan, Y., Murata, T., Shakur, Y., Degerman, E., and Manganiello, V. C. (2000) J. Biol. Chem. 275, 12331-12338
13. Kovala, T., Sanwal, B. D., and Ball, E. H. (1997) Biochemistry 36, 2968-2976
14. Richter, W., and Conti, M. (2002) J. Biol. Chem. 277, 40212-40221
15. Fink, T. L., Francis, S. H., Beasley, A., Grimes, K. A., and Corbin, J. D. (1999) J. Biol. Chem. 274, 34613-34620
16. Muradov, K. G., Boyd, K. K., Martinez, S. E., Beavo, J. A., and Artemyev, N. O. (2003) J. Biol. Chem. 278, 10594-10601
17. Kameni Tscheudji, J. F., Lebeau, L., Virmaux, N., Maftei, C. G., Cote, R. H., Lugnier, C., and Schultz, P. (2001) J. Mol. Biol. 310, 781-791
18. Beard, M. B., Olsen, A. E., Jones, R. E., Erdogan, S., Houslay, M. D., and Bolger, G. B. (2000) J. Biol. Chem. 275, 10349-10358
19. Lee, M. E., Markowitz, J., Lee, J. O., and Lee, H. (2002) FEBS Lett. 530, 53-58
20. Tenor, H., and Schudt, C. (1999) in Anti-inflammatory Drugs in Asthma (Sampson, A. P., and Church, M. K., eds) pp. 87-135, Birkhäuser Verlag, Basel
21. Rocque, W. J., Holmes, W. D., Patel, I. R., Dougherty, R. W., Ittoop, O., Overton, L., Hoffman, C. R., Wisely, G. B., Willard, D. H., and Luther, M. A. (1997) Protein Expression Purif. 9, 191-202
22. Rocque, W. J., Tian, G., Wiseman, J. S., Holmes, W. D., Zajac-Thompson, I., Willard, D. H., Patel, I. R., Wisely, G. B., Clay, W. C., Kadwell, S. H., Hoffman, C. R., and Luther, M. A. (1997) Biochemistry 36, 14250-14261
23. Laliberte, F., Han, Y., Govindarajan, A., Giroux, A., Liu, S., Bobechko, B., Lario, P., Bartlett, A., Gorseth, E., Gresser, M., and Huang, Z. (2000) Biochemistry 39, 6449-6458
24. Liu, S., Laliberte, F., Bobechko, B., Bartlett, A., Lario, P., Gorseth, E., Van Hamme, J., Gresser, M. J., and Huang, Z. (2001) Biochemistry 40, 10179-10186
25. Siegel, L. M., and Monty, K. J. (1966) Biochim. Biophys. Acta 112, 346-362
26. Laemmli, U. K. (1970) Nature 227, 680-685
27. Thompson, W. J., and Appleman, M. M. (1971) Biochemistry 10, 311-316
28. Lim, J., Pahlke, G., and Conti, M. (1999) J. Biol. Chem. 274, 19677-19685
29. Oki, N., Takahashi, S. I., Hidaka, H., and Conti, M. (2000) J. Biol. Chem. 275, 10831-10837
30. Bolger, G. B., Peden, A. H., Steele, M. R., MacKenzie, C., McEwan, D. G., Wallace, D. A., Huston, E., Baillie, G. S., and Houslay, M. D. (2003) J. Biol. Chem. 278, 33351-33363
31. Sette, C., Vicini, E., and Conti, M. (1994) J. Biol. Chem. 269, 18271-18274
32. Jin, S. L., Bushnik, T., Lan, L., and Conti, M. (1998) J. Biol. Chem. 273, 19672-19678
33. Jin, S. L., and Conti, M. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 7628-7633
34. Huston, E., Pooley, L., Julien, P., Scotland, G., McPhee, I., Sullivan, M., Bolger, G., and Houslay, M. D. (1996) J. Biol. Chem. 271, 31334-31344
35. Hoffmann, R., Baillie, G. S., MacKenzie, S. J., Yarwood, S. J., and Houslay, M. D. (1999) EMBO J. 18, 893-903
36. Baillie, G. S., MacKenzie, S. J., McPhee, I., and Houslay, M. D. (2000) Br. J. Pharmacol. 131, 811-819
37. Norton, A. W., D'Amours, M. R., Grazio, H. J., Hebert, T. L., and Cote, R. H. (2000) J. Biol. Chem. 275, 38611-38619