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Volumn 2006, Issue , 2006, Pages

MicroRNAs in gene regulation: When the smallest governs it all

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DICER; EXPORTIN 5; FRAGILE X MENTAL RETARDATION PROTEIN; GENE PRODUCT; MICRORNA; NUCLEASE; NUCLEASE TUDOR; NUCLEOTIDE; POTEIN RISC; PROTEIN AGO2; PROTEIN DGCR8; PROTEIN DROSHA; PROTEIN R2D2; PROTEIN RITS; PROTEIN TRBP1; PROTEIN TRBP2; PROTEIN VIG; RIBONUCLEASE III; RNA BINDING PROTEIN; RNA POLYMERASE II; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 33746793605     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/JBB/2006/69616     Document Type: Review
Times cited : (111)

References (205)
  • 1
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • C Napoli C Lemieux R Jorgensen Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2 4 1990 279 289
    • (1990) Plant Cell , vol.2 , Issue.4 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 2
    • 0025134418 scopus 로고
    • Altered gene expression in plants due to trans interactions between homologous genes
    • R Jorgensen Altered gene expression in plants due to trans interactions between homologous genes. Trends in Biotechnology 8 12 1990 340 344
    • (1990) Trends in Biotechnology , vol.8 , Issue.12 , pp. 340-344
    • Jorgensen, R.1
  • 3
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • R C Lee R L Feinbaum V Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75 5 1993 843 854
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 4
    • 0025942586 scopus 로고
    • Negative regulatory sequences in the lin-14 3′-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development
    • B Wightman T R Burglin J Gatto P Arasu G Ruvkun Negative regulatory sequences in the lin-14 3′-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development. Genes and Development 5 10 1991 1813 1824
    • (1991) Genes and Development , vol.5 , Issue.10 , pp. 1813-1824
    • Wightman, B.1    Burglin, T.R.2    Gatto, J.3    Arasu, P.4    Ruvkun, G.5
  • 5
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • B Wightman I Ha G Ruvkun Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75 5 1993 855 862
    • (1993) Cell , vol.75 , Issue.5 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 6
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • A Fire S Xu M K Montgomery S A Kostas S E Driver C C Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 6669 1998 806 811
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 7
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • david.baulcombe@bbsrc.ac.uk
    • A J Hamilton D C Baulcombe david.baulcombe@bbsrc.ac.uk A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286 5441 1999 950 952
    • (1999) Science , vol.286 , Issue.5441 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 8
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • P D Zamore T Tuschl P A Sharp D P Bartel RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101 1 2000 25 33
    • (2000) Cell , vol.101 , Issue.1 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 9
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • S M Elbashir W Lendeckel T Tuschl RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes and Development 15 2 2001 188 200
    • (2001) Genes and Development , vol.15 , Issue.2 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 10
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • M Lagos-Quintana R Rauhut W Lendeckel T Tuschl Identification of novel genes coding for small expressed RNAs. Science 294 5543 2001 853 858
    • (2001) Science , vol.294 , Issue.5543 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 11
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • N C Lau L P Lim E G Weinstein D P Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294 5543 2001 858 862
    • (2001) Science , vol.294 , Issue.5543 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 12
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • R C Lee V Ambros An extensive class of small RNAs in Caenorhabditis elegans. Science 294 5543 2001 862 864
    • (2001) Science , vol.294 , Issue.5543 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 13
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • hannon@cshl.org
    • A M Denli B BJ Tops R HA Plasterk R F Ketting G J Hannon hannon@cshl.org Processing of primary microRNAs by the Microprocessor complex. Nature 432 7014 2004 231 235
    • (2004) Nature , vol.432 , Issue.7014 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.J.2    Plasterk, R.H.A.3    Ketting, R.F.4    Hannon, G.J.5
  • 14
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • R I Gregory K-P Yan G Amuthan The Microprocessor complex mediates the genesis of microRNAs. Nature 432 7014 2004 235 240
    • (2004) Nature , vol.432 , Issue.7014 , pp. 235-240
    • Gregory, R.I.1    Yan, K.-P.2    Amuthan, G.3
  • 15
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • narrykim@snu.ac.kr
    • J Han Y Lee K-H Yeom Y-K Kim H Jin V N Kim narrykim@snu.ac.kr The Drosha-DGCR8 complex in primary microRNA processing. Genes and Development 18 24 2004 3016 3027
    • (2004) Genes and Development , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.-H.3    Kim, Y.-K.4    Jin, H.5    Kim, V.N.6
  • 16
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • ttuschl@rockefeller.edu
    • M Landthaler A Yalcin T Tuschl ttuschl@rockefeller.edu The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Current Biology 14 23 2004 2162 2167
    • (2004) Current Biology , vol.14 , Issue.23 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 17
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • culle002@mc.duke.edu
    • X Cai C H Hagedorn B R Cullen culle002@mc.duke.edu Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10 12 2004 1957 1966
    • (2004) RNA , vol.10 , Issue.12 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 18
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Y Lee C Ahn J Han The nuclear RNase III Drosha initiates microRNA processing. Nature 425 6956 2003 415 419
    • (2003) Nature , vol.425 , Issue.6956 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 19
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Y Lee K Jeon J-T Lee S Kim V N Kim MicroRNA maturation: stepwise processing and subcellular localization. EMBO Journal 21 17 2002 4663 4670
    • (2002) EMBO Journal , vol.21 , Issue.17 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.-T.3    Kim, S.4    Kim, V.N.5
  • 20
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • dg@zmbh.uni-heidelberg.de
    • M T Bohnsack K Czaplinski D Görlich dg@zmbh.uni-heidelberg.de Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10 2 2004 185 191
    • (2004) RNA , vol.10 , Issue.2 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Görlich, D.3
  • 21
    • 0037033792 scopus 로고    scopus 로고
    • Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins
    • A M Brownawell I G Macara Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins. Journal of Cell Biology 156 1 2002 53 64
    • (2002) Journal of Cell Biology , vol.156 , Issue.1 , pp. 53-64
    • Brownawell, A.M.1    MacAra, I.G.2
  • 22
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • dahlberg@wisc.edu ulrike.kutay@bc.biol.ethz.ch
    • E Lund S Güttinger A Calado J E Dahlberg dahlberg@wisc.edu U Kutay ulrike.kutay@bc.biol.ethz.ch Nuclear export of microRNA precursors. Science 303 5654 2004 95 98
    • (2004) Science , vol.303 , Issue.5654 , pp. 95-98
    • Lund, E.1    Güttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 23
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • R Yi Y Qin I G Macara B R Cullen Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes and Development 17 24 2003 3011 3016
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    MacAra, I.G.3    Cullen, B.R.4
  • 24
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • shiekhattar@wistar.org
    • R I Gregory T P Chendrimada N Cooch R Shiekhattar shiekhattar@wistar.org Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123 4 2005 631 640
    • (2005) Cell , vol.123 , Issue.4 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 25
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • dbartel@wi.mit.edu
    • D P Bartel dbartel@wi.mit.edu MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 2 2004 281 297
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 26
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Y Lee M Kim J Han MicroRNA genes are transcribed by RNA polymerase II. EMBO Journal 23 20 2004 4051 4060
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3
  • 27
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • abradley@sanger.ac.uk
    • A Rodriguez S Griffiths-Jones J L Ashurst A Bradley abradley@sanger.ac.uk Identification of mammalian microRNA host genes and transcription units. Genome Research 14 10A 2004 1902 1910
    • (2004) Genome Research , vol.14 , Issue.10 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 30
    • 0034711308 scopus 로고    scopus 로고
    • Human RNase III is a 160-kDa protein involved in preribosomal RNA processing
    • H Wu H Xu L J Miraglia S T Crooke Human RNase III is a 160-kDa protein involved in preribosomal RNA processing. Journal of Biological Chemistry 275 47 2000 36957 36965
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.47 , pp. 36957-36965
    • Wu, H.1    Xu, H.2    Miraglia, L.J.3    Crooke, S.T.4
  • 31
    • 0034615578 scopus 로고    scopus 로고
    • A novel type of RNase III family proteins in eukaryotes
    • sarjeet.gill@ucr.edu
    • V Filippov V Solovyev M Filippova S S Gill sarjeet.gill@ucr.edu A novel type of RNase III family proteins in eukaryotes. Gene 245 1 2000 213 221
    • (2000) Gene , vol.245 , Issue.1 , pp. 213-221
    • Filippov, V.1    Solovyev, V.2    Filippova, M.3    Gill, S.S.4
  • 32
    • 0141860062 scopus 로고    scopus 로고
    • Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location
    • rnichol@genetics.wayne.edu krfortin@hotmail.com anichol@biology.biosci. wayne.edu
    • K R Fortin krfortin@hotmail.com R H Nicholson rnichol@genetics.wayne.edu A W Nicholson anichol@biology.biosci.wayne.edu Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location. BMC Genomics 3 1 2002 26
    • (2002) BMC Genomics , vol.3 , Issue.1 , pp. 26
    • Fortin, K.R.1    Nicholson, R.H.2    Nicholson, A.W.3
  • 33
    • 0344668836 scopus 로고    scopus 로고
    • Human let-7 stem-loop precursors harbor features of RNase III cleavage products
    • bertrand@igm.cnrs-mop.fr
    • E Basyuk F Suavet A Doglio R Bordonné E Bertrand bertrand@igm.cnrs-mop.fr Human let-7 stem-loop precursors harbor features of RNase III cleavage products. Nucleic Acids Research 31 22 2003 6593 6597
    • (2003) Nucleic Acids Research , vol.31 , Issue.22 , pp. 6593-6597
    • Basyuk, E.1    Suavet, F.2    Doglio, A.3    Bordonné, R.4    Bertrand, E.5
  • 34
    • 0037273432 scopus 로고    scopus 로고
    • Sequence requirements for micro RNA processing and function in human cells
    • Y Zeng B R Cullen Sequence requirements for micro RNA processing and function in human cells. RNA 9 1 2003 112 123
    • (2003) RNA , vol.9 , Issue.1 , pp. 112-123
    • Zeng, Y.1    Cullen, B.R.2
  • 35
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • filipowi@fmi.ch
    • H Zhang F A Kolb L Jaskiewicz E Westhof W Filipowicz filipowi@fmi.ch Single processing center models for human Dicer and bacterial RNase III. Cell 118 1 2004 57 68
    • (2004) Cell , vol.118 , Issue.1 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 36
    • 0035839938 scopus 로고    scopus 로고
    • Biology of EWS/ETS fusions in Ewing's family tumors
    • A Arvand C T Denny Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene 20 40 2001 5747 5754
    • (2001) Oncogene , vol.20 , Issue.40 , pp. 5747-5754
    • Arvand, A.1    Denny, C.T.2
  • 37
    • 0141458167 scopus 로고    scopus 로고
    • Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome
    • hyamag@sc.itc.keio.ac.jp deepak.srivastava@utsouthwestern.edu
    • H Yamagishi hyamag@sc.itc.keio.ac.jp D Srivastava deepak. srivastava@utsouthwestern.edu Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends in Molecular Medicine 9 9 2003 383 389
    • (2003) Trends in Molecular Medicine , vol.9 , Issue.9 , pp. 383-389
    • Yamagishi, H.1    Srivastava, D.2
  • 38
    • 0037466486 scopus 로고    scopus 로고
    • Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region
    • shimizu@dmb.med.keio.ac.jp
    • A Shiohama T Sasaki S Noda S Minoshima N Shimizu shimizu@dmb.med.keio.ac. jp Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochemical and Biophysical Research Communications 304 1 2003 184 190
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , Issue.1 , pp. 184-190
    • Shiohama, A.1    Sasaki, T.2    Noda, S.3    Minoshima, S.4    Shimizu, N.5
  • 39
    • 12844285548 scopus 로고    scopus 로고
    • Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs
    • R Yi B P Doehle Y Qin I G Macara B R Cullen Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA 11 2 2005 220 226
    • (2005) RNA , vol.11 , Issue.2 , pp. 220-226
    • Yi, R.1    Doehle, B.P.2    Qin, Y.3    MacAra, I.G.4    Cullen, B.R.5
  • 40
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
    • Y Zeng B R Cullen Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Research 32 16 2004 4776 4785
    • (2004) Nucleic Acids Research , vol.32 , Issue.16 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 42
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • E Bernstein A A Caudy S M Hammond G J Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 6818 2001 363 366
    • (2001) Nature , vol.409 , Issue.6818 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 43
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • A Grishok A E Pasquinelli D Conte Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 1 2001 23 34
    • (2001) Cell , vol.106 , Issue.1 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3
  • 44
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • S W Knight B L Bass A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293 5538 2001 2269 2271
    • (2001) Science , vol.293 , Issue.5538 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 45
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
    • G Hutvágner J McLachlan A E Pasquinelli É. Bálint T Tuschl P D Zamore A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA. Science 293 5531 2001 834 838
    • (2001) Science , vol.293 , Issue.5531 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Bálint, É.4    Tuschl, T.5    Zamore, P.D.6
  • 48
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • H Zhang F A Kolb V Brondani E Billy W Filipowicz Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO Journal 21 21 2002 5875 5885
    • (2002) EMBO Journal , vol.21 , Issue.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 50
  • 51
  • 52
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • C Kanellopoulou S A Muljo A L Kung Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes and Development 19 4 2005 489 501
    • (2005) Genes and Development , vol.19 , Issue.4 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 54
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • S M Hammond S Boettcher A A Caudy R Kobayashi G J Hannon Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293 5532 2001 1146 1150
    • (2001) Science , vol.293 , Issue.5532 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 55
    • 0036791671 scopus 로고    scopus 로고
    • A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
    • A Ishizuka M C Siomi H Siomi A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes and Development 16 19 2002 2497 2508
    • (2002) Genes and Development , vol.16 , Issue.19 , pp. 2497-2508
    • Ishizuka, A.1    Siomi, M.C.2    Siomi, H.3
  • 56
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • T P Chendrimada R I Gregory E Kumaraswamy TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436 7051 2005 740 744
    • (2005) Nature , vol.436 , Issue.7051 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3
  • 57
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • A D Haase L Jaskiewicz H Zhang TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Reports 6 10 2005 961 967
    • (2005) EMBO Reports , vol.6 , Issue.10 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3
  • 59
    • 0025876881 scopus 로고
    • Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR
    • A Gatignol A Buckler-White B Berkhout K-T Jeang Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. Science 251 5001 1991 1597 1600
    • (1991) Science , vol.251 , Issue.5001 , pp. 1597-1600
    • Gatignol, A.1    Buckler-White, A.2    Berkhout, B.3    Jeang, K.-T.4
  • 60
    • 0033773221 scopus 로고    scopus 로고
    • Characterization of TRBP1 and TRBP2: Stable stem-loop structure at the 5′ end of TRBP2 mRNA resembles HIV-1 TAR and is not found in its processed pseudogene
    • M Duarte K Graham A Daher Characterization of TRBP1 and TRBP2: stable stem-loop structure at the 5′ end of TRBP2 mRNA resembles HIV-1 TAR and is not found in its processed pseudogene. Journal of Biomedical Science 7 6 2000 494 506
    • (2000) Journal of Biomedical Science , vol.7 , Issue.6 , pp. 494-506
    • Duarte, M.1    Graham, K.2    Daher, A.3
  • 61
    • 0035823590 scopus 로고    scopus 로고
    • Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression
    • A Daher M Longuet D Dorin Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression. Journal of Biological Chemistry 276 36 2001 33899 33905
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.36 , pp. 33899-33905
    • Daher, A.1    Longuet, M.2    Dorin, D.3
  • 62
    • 0029693144 scopus 로고    scopus 로고
    • Sequential steps in Tat trans-activation of HIV-1 mediated through cellular DNA, RNA, and protein binding factors
    • A Gatignol M Duarte L Daviet Y-N Chang K-T Jeang Sequential steps in Tat trans-activation of HIV-1 mediated through cellular DNA, RNA, and protein binding factors. Gene Expression 5 4-5 1996 217 228
    • (1996) Gene Expression , vol.5 , Issue.45 , pp. 217-228
    • Gatignol, A.1    Duarte, M.2    Daviet, L.3    Chang, Y.-N.4    Jeang, K.-T.5
  • 63
    • 0030972471 scopus 로고    scopus 로고
    • Specific repression of Tax trans-activation by TAR RNA-binding protein TRBP
    • meister@lmb.uni-muenchen.de
    • M Donzeau E-L Winnacker M Meisterernst meister@lmb.uni-muenchen.de Specific repression of Tax trans-activation by TAR RNA-binding protein TRBP. Journal of Virology 71 4 1997 2628 2635
    • (1997) Journal of Virology , vol.71 , Issue.4 , pp. 2628-2635
    • Donzeau, M.1    Winnacker, E.-L.2    Meisterernst, M.3
  • 65
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • K Förstemann Y Tomari T Du Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biology 3 2005 7 e236
    • (2005) PLoS Biology , vol.3 , Issue.7
    • Förstemann, K.1    Tomari, Y.2    Du, T.3
  • 66
    • 22744454230 scopus 로고    scopus 로고
    • Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • K Saito A Ishizuka H Siomi M C Siomi Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biology 3 2005 7 e235
    • (2005) PLoS Biology , vol.3 , Issue.7
    • Saito, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 67
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Q Liu T A Rand S Kalidas R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301 5641 2003 1921 1925
    • (2003) Science , vol.301 , Issue.5641 , pp. 1921-1925
    • Liu, Q.1    Rand, T.A.2    Kalidas, S.3
  • 68
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • craig.mello@ummed.edu
    • A Grishok H Tabara C C Mello craig.mello@ummed.edu Genetic requirements for inheritance of RNAi in C. elegans. Science 287 5462 2000 2494 2497
    • (2000) Science , vol.287 , Issue.5462 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.C.3
  • 69
    • 0037188904 scopus 로고    scopus 로고
    • The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
    • H Tabara E Yigit H Siomi C C Mello The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109 7 2002 861 871
    • (2002) Cell , vol.109 , Issue.7 , pp. 861-871
    • Tabara, H.1    Yigit, E.2    Siomi, H.3    Mello, C.C.4
  • 70
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • phillip.zamore@umassmed.edu
    • D S Schwarz G Hutvágner T Du Z Xu N Aronin P D Zamore phillip.zamore@umassmed.edu Asymmetry in the assembly of the RNAi enzyme complex. Cell 115 2 2003 199 208
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvágner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 72
    • 0142227238 scopus 로고    scopus 로고
    • R2D2 leads the silencing trigger to mRNA's death star
    • J L Pellino E J Sontheimer R2D2 leads the silencing trigger to mRNA's death star. Cell 115 2 2003 132 133
    • (2003) Cell , vol.115 , Issue.2 , pp. 132-133
    • Pellino, J.L.1    Sontheimer, E.J.2
  • 73
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • lee_lim@merck.com
    • L P Lim lee_lim@merck.com N C Lau P Garrett-Engele Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433 7027 2005 769 773
    • (2005) Nature , vol.433 , Issue.7027 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 74
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • S Yekta I-H Shih D P Bartel MicroRNA-directed cleavage of HOXB8 mRNA. Science 304 5670 2004 594 596
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.-H.2    Bartel, D.P.3
  • 75
    • 23944514849 scopus 로고    scopus 로고
    • Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
    • S Bagga J Bracht S Hunter Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122 4 2005 553 563
    • (2005) Cell , vol.122 , Issue.4 , pp. 553-563
    • Bagga, S.1    Bracht, J.2    Hunter, S.3
  • 76
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • S M Hammond E Bernstein D Beach G J Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404 6775 2000 293 296
    • (2000) Nature , vol.404 , Issue.6775 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 77
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • A Nykänen B Haley P D Zamore ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107 3 2001 309 321
    • (2001) Cell , vol.107 , Issue.3 , pp. 309-321
    • Nykänen, A.1    Haley, B.2    Zamore, P.D.3
  • 78
    • 1842766252 scopus 로고    scopus 로고
    • A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila
    • erik@northwestern.edu
    • J W Pham J L Pellino Y S Lee R W Carthew E J Sontheimer erik@northwestern.edu A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117 1 2004 83 94
    • (2004) Cell , vol.117 , Issue.1 , pp. 83-94
    • Pham, J.W.1    Pellino, J.L.2    Lee, Y.S.3    Carthew, R.W.4    Sontheimer, E.J.5
  • 79
    • 27744590896 scopus 로고    scopus 로고
    • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
    • C Matranga Y Tomari C Shin D P Bartel P D Zamore Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123 4 2005 607 620
    • (2005) Cell , vol.123 , Issue.4 , pp. 607-620
    • Matranga, C.1    Tomari, Y.2    Shin, C.3    Bartel, D.P.4    Zamore, P.D.5
  • 80
    • 27744506761 scopus 로고    scopus 로고
    • Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
    • xwang@biochem.swmed.edu
    • T A Rand S Petersen F Du X Wang xwang@biochem.swmed.edu Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123 4 2005 621 629
    • (2005) Cell , vol.123 , Issue.4 , pp. 621-629
    • Rand, T.A.1    Petersen, S.2    Du, F.3    Wang, X.4
  • 81
    • 0037087780 scopus 로고    scopus 로고
    • MiRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
    • Z Mourelatos J Dostie S Paushkin miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes and Development 16 6 2002 720 728
    • (2002) Genes and Development , vol.16 , Issue.6 , pp. 720-728
    • Mourelatos, Z.1    Dostie, J.2    Paushkin, S.3
  • 82
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • rrparker@u.arizona.edu
    • J Liu M A Valencia-Sanchez G J Hannon R Parker rrparker@u.arizona.edu MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nature Cell Biology 7 7 2005 719 723
    • (2005) Nature Cell Biology , vol.7 , Issue.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 83
    • 15444379718 scopus 로고    scopus 로고
    • Processing bodies require RNA for assembly and contain nontranslating mRNAs
    • D Teixeira U Sheth MA Valencia-Sanchez M Brengues R Parker Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA 11 4 2005 371 382
    • (2005) RNA , vol.11 , Issue.4 , pp. 371-382
    • Teixeira, D.1    Sheth, U.2    Ma, V.3    Brengues, M.4    Parker, R.5
  • 84
    • 0036223709 scopus 로고    scopus 로고
    • A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles
    • T Eystathioy E KL Chan S A Tenenbaum J D Keene K Griffith M J Fritzler A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Molecular Biology of the Cell 13 4 2002 1338 1351
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.4 , pp. 1338-1351
    • Eystathioy, T.1    Chan, E.K.L.2    Tenenbaum, S.A.3    Keene, J.D.4    Griffith, K.5    Fritzler, M.J.6
  • 85
    • 0141856112 scopus 로고    scopus 로고
    • The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies
    • fritzler@ucalgary.ca
    • T Eystathioy A Jakymiw E KL Chan B Séraphin N Cougot M J Fritzler fritzler@ucalgary.ca The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies. RNA 9 10 2003 1171 1173
    • (2003) RNA , vol.9 , Issue.10 , pp. 1171-1173
    • Eystathioy, T.1    Jakymiw, A.2    Chan, E.K.L.3    Séraphin, B.4    Cougot, N.5    Fritzler, M.J.6
  • 87
    • 28544435974 scopus 로고    scopus 로고
    • Disruption of GW bodies impairs mammalian RNA interference
    • A Jakymiw S Lian T Eystathioy Disruption of GW bodies impairs mammalian RNA interference. Nature Cell Biology 7 12 2005 1167 1174
    • (2005) Nature Cell Biology , vol.7 , Issue.12 , pp. 1167-1174
    • Jakymiw, A.1    Lian, S.2    Eystathioy, T.3
  • 89
    • 20444464014 scopus 로고    scopus 로고
    • Cytoplasmic and nuclear retained DMPK mRNAs are targets for RNA interference in myotonic dystrophy cells
    • M-A Langlois C Boniface G Wang Cytoplasmic and nuclear retained DMPK mRNAs are targets for RNA interference in myotonic dystrophy cells. Journal of Biological Chemistry 280 17 2005 16949 16954
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 16949-16954
    • Langlois, M.-A.1    Boniface, C.2    Wang, G.3
  • 90
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • T A Volpe C Kidner I M Hall G Teng S IS Grewal R A Martienssen Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297 5588 2002 1833 1837
    • (2002) Science , vol.297 , Issue.5588 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.S.5    Martienssen, R.A.6
  • 91
    • 0035043250 scopus 로고    scopus 로고
    • Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily
    • Y Kataoka M Takeichi T Uemura Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes to Cells 6 4 2001 313 325
    • (2001) Genes to Cells , vol.6 , Issue.4 , pp. 313-325
    • Kataoka, Y.1    Takeichi, M.2    Uemura, T.3
  • 92
    • 0034306266 scopus 로고    scopus 로고
    • Domains in gene silencing and cell differentiation proteins: The novel PAZ domain and redefinition of the Piwi domain
    • L Cerutti N Mian A Bateman Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain. Trends in Biochemical Sciences 25 10 2000 481 482
    • (2000) Trends in Biochemical Sciences , vol.25 , Issue.10 , pp. 481-482
    • Cerutti, L.1    Mian, N.2    Bateman, A.3
  • 93
    • 0042124978 scopus 로고    scopus 로고
    • Identification of eight members of the Argonaute family in the human genome small star, filled
    • 12906857
    • T Sasaki A Shiohama S Minoshima N Shimizu Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics 82 3 2003 323 330 12906857
    • (2003) Genomics , vol.82 , Issue.3 , pp. 323-330
    • Sasaki, T.1    Shiohama, A.2    Minoshima, S.3    Shimizu, N.4
  • 95
    • 4444368187 scopus 로고    scopus 로고
    • Argonaute2 is the catalytic engine of mammalian RNAi
    • J Liu M A Carmell F V Rivas Argonaute2 is the catalytic engine of mammalian RNAi. Science 305 5689 2004 1437 1441
    • (2004) Science , vol.305 , Issue.5689 , pp. 1437-1441
    • Liu, J.1    Carmell, M.A.2    Rivas, F.V.3
  • 96
    • 0942279635 scopus 로고    scopus 로고
    • RNAi-mediated targeting of heterochromatin by the RITS complex
    • A Verdel S Jia S Gerber RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303 5658 2004 672 676
    • (2004) Science , vol.303 , Issue.5658 , pp. 672-676
    • Verdel, A.1    Jia, S.2    Gerber, S.3
  • 97
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • M A Carmell Z Xuan M Q Zhang G J Hannon The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes and Development 16 21 2002 2733 2742
    • (2002) Genes and Development , vol.16 , Issue.21 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 98
    • 0642345790 scopus 로고    scopus 로고
    • Structure and conserved RNA binding of the PAZ domain
    • Ming-Ming.Zhou@mssm.edu
    • K S Yan S Yan A Farooq A Han L Zeng M-M Zhou Ming-Ming.Zhou@mssm.edu Structure and conserved RNA binding of the PAZ domain. Nature 426 6965 2003 468 474
    • (2003) Nature , vol.426 , Issue.6965 , pp. 468-474
    • Yan, K.S.1    Yan, S.2    Farooq, A.3    Han, A.4    Zeng, L.5    Zhou, M.-M.6
  • 100
    • 0345490960 scopus 로고    scopus 로고
    • The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
    • J-J Song J Liu N H Tolia The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nature Structural Biology 10 12 2003 1026 1032
    • (2003) Nature Structural Biology , vol.10 , Issue.12 , pp. 1026-1032
    • Song, J.-J.1    Liu, J.2    Tolia, N.H.3
  • 101
    • 0345359925 scopus 로고    scopus 로고
    • Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
    • sattler@embl.de
    • A Lingel B Simon E Izaurralde M Sattler sattler@embl.de Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain. Nature 426 6965 2003 465 469
    • (2003) Nature , vol.426 , Issue.6965 , pp. 465-469
    • Lingel, A.1    Simon, B.2    Izaurralde, E.3    Sattler, M.4
  • 102
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • leemor@cshl.edu
    • J-J Song S K Smith G J Hannon L Joshua-Tor leemor@cshl.edu Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305 5689 2004 1434 1437
    • (2004) Science , vol.305 , Issue.5689 , pp. 1434-1437
    • Song, J.-J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 103
    • 11244279683 scopus 로고    scopus 로고
    • Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
    • J S Parker S M Roe D Barford Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity. EMBO Journal 23 24 2004 4727 4737
    • (2004) EMBO Journal , vol.23 , Issue.24 , pp. 4727-4737
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 104
    • 15844371219 scopus 로고    scopus 로고
    • Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
    • pateld@mskcc.org
    • J-B Ma Y-R Yuan G Meister Y Pei T Tuschl D J Patel pateld@mskcc.org Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434 7033 2005 666 670
    • (2005) Nature , vol.434 , Issue.7033 , pp. 666-670
    • Ma, J.-B.1    Yuan, Y.-R.2    Meister, G.3    Pei, Y.4    Tuschl, T.5    Patel, D.J.6
  • 105
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
    • david.barford@icr.ac.uk
    • J S Parker S M Roe D Barford david.barford@icr.ac.uk Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 434 7033 2005 663 666
    • (2005) Nature , vol.434 , Issue.7033 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 106
    • 2342626647 scopus 로고    scopus 로고
    • The RNA-induced silencing complex is a
    • Mg2+-dependent endonuclease
    • D S Schwarz Y Tomari P D Zamore The RNA-induced silencing complex is a Mg 2+-dependent endonuclease. Current Biology 14 9 2004 787 791
    • (2004) Current Biology , vol.14 , Issue.9 , pp. 787-791
    • Schwarz, D.S.1    Tomari, Y.2    Zamore, P.D.3
  • 109
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • S M Elbashir J Martinez A Patkaniowska W Lendeckel T Tuschl Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO Journal 20 23 2001 6877 6888
    • (2001) EMBO Journal , vol.20 , Issue.23 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 110
    • 4644310115 scopus 로고    scopus 로고
    • Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
    • R S Pillai C G Artus W Filipowicz Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA 10 10 2004 1518 1525
    • (2004) RNA , vol.10 , Issue.10 , pp. 1518-1525
    • Pillai, R.S.1    Artus, C.G.2    Filipowicz, W.3
  • 111
    • 24644480213 scopus 로고    scopus 로고
    • Inhibition of translational initiation by let-7 MicroRNA in human cells
    • R S Pillai S N Bhattacharyya C G Artus Inhibition of translational initiation by let-7 MicroRNA in human cells. Science 309 5740 2005 1573 1576
    • (2005) Science , vol.309 , Issue.5740 , pp. 1573-1576
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Artus, C.G.3
  • 113
    • 0036591664 scopus 로고    scopus 로고
    • Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes
    • B Bardoni J-L Mandel Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes. Current Opinion in Genetics and Development 12 3 2002 284 293
    • (2002) Current Opinion in Genetics and Development , vol.12 , Issue.3 , pp. 284-293
    • Bardoni, B.1    Mandel, J.-L.2
  • 114
    • 0027327486 scopus 로고
    • The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein
    • H Siomi M C Siomi R L Nussbaum G Dreyfuss The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein. Cell 74 2 1993 291 298
    • (1993) Cell , vol.74 , Issue.2 , pp. 291-298
    • Siomi, H.1    Siomi, M.C.2    Nussbaum, R.L.3    Dreyfuss, G.4
  • 115
    • 0027236971 scopus 로고
    • Characterization and localization of the FMR-1 gene product associated with fragile X syndrome
    • C Verhelj C E Bakker E de Graaff Characterization and localization of the FMR-1 gene product associated with fragile X syndrome. Nature 363 6431 1993 722 724
    • (1993) Nature , vol.363 , Issue.6431 , pp. 722-724
    • Verhelj, C.1    Bakker, C.E.2    De Graaff, E.3
  • 117
    • 0035368955 scopus 로고    scopus 로고
    • The fragile X mental retardation protein inhibits translation via interacting with mRNA
    • Z Li Y Zhang L Ku K D Wilkinson S T Warren Y Feng The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Research 29 11 2001 2276 2283
    • (2001) Nucleic Acids Research , vol.29 , Issue.11 , pp. 2276-2283
    • Li, Z.1    Zhang, Y.2    Ku, L.3    Wilkinson, K.D.4    Warren, S.T.5    Feng, Y.6
  • 118
    • 0037112805 scopus 로고    scopus 로고
    • Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression
    • edward.khandjian@crsfa.ulaval.ca
    • R Mazroui M E Hout S Tremblay C Fillion Y Labelle E W Khandjian edward.khandjian@crsfa.ulaval.ca Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression. Human Molecular Genetics 11 24 2002 3007 3017
    • (2002) Human Molecular Genetics , vol.11 , Issue.24 , pp. 3007-3017
    • Mazroui, R.1    Hout, M.E.2    Tremblay, S.3    Fillion, C.4    Labelle, Y.5    Khandjian, E.W.6
  • 119
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • A A Caudy M Myers G J Hannon S M Hammond Fragile X-related protein and VIG associate with the RNA interference machinery. Genes and Development 16 19 2002 2491 2496
    • (2002) Genes and Development , vol.16 , Issue.19 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 120
    • 1642540373 scopus 로고    scopus 로고
    • Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
    • P Jin D C Zarnescu S Ceman Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nature Neuroscience 7 2 2004 113 117
    • (2004) Nature Neuroscience , vol.7 , Issue.2 , pp. 113-117
    • Jin, P.1    Zarnescu, D.C.2    Ceman, S.3
  • 121
    • 33746852731 scopus 로고    scopus 로고
    • Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs
    • 64347
    • I Plante L Davidovic D L Ouellet Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs. Journal of Biomedicine and Biotechnology 64347 2006 2006
    • (2006) Journal of Biomedicine and Biotechnology , vol.2006
    • Plante, I.1    Davidovic, L.2    Ouellet, D.L.3
  • 122
    • 0035793586 scopus 로고    scopus 로고
    • Identification and cDNA cloning of a novel RNA-binding protein that Interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA
    • heatonj@umich.edu
    • J H Heaton heatonj@umich.edu W M Dlakic M Dlakic T D Gelehrter Identification and cDNA cloning of a novel RNA-binding protein that Interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA. Journal of Biological Chemistry 276 5 2001 3341 3347
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.5 , pp. 3341-3347
    • Heaton, J.H.1    Dlakic, W.M.2    Dlakic, M.3    Gelehrter, T.D.4
  • 123
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Q Jing S Huang S Guth Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120 5 2005 623 634
    • (2005) Cell , vol.120 , Issue.5 , pp. 623-634
    • Jing, Q.1    Huang, S.2    Guth, S.3
  • 124
    • 0141843655 scopus 로고    scopus 로고
    • A micrococcal nuclease homologue in RNAi effector complexes
    • A A Caudy R F Ketting S M Hammond A micrococcal nuclease homologue in RNAi effector complexes. Nature 425 6956 2003 411 414
    • (2003) Nature , vol.425 , Issue.6956 , pp. 411-414
    • Caudy, A.A.1    Ketting, R.F.2    Hammond, S.M.3
  • 125
    • 2442495329 scopus 로고    scopus 로고
    • RISC is a 5′ phosphomonoester-producing RNA endonuclease
    • J Martinez T Tuschl RISC is a 5′ phosphomonoester-producing RNA endonuclease. Genes and Development 18 9 2004 975 980
    • (2004) Genes and Development , vol.18 , Issue.9 , pp. 975-980
    • Martinez, J.1    Tuschl, T.2
  • 126
    • 2342611288 scopus 로고
    • Mode of action of micrococcal phosphodiesterase
    • K K Reddi Mode of action of micrococcal phosphodiesterase. Nature 187 1960 74 75
    • (1960) Nature , vol.187 , pp. 74-75
    • Reddi, K.K.1
  • 127
    • 0035997389 scopus 로고    scopus 로고
    • RNA editing by adenosine deaminases that act on RNA
    • B L Bass RNA editing by adenosine deaminases that act on RNA. Annual Review of Biochemistry 71 2002 817 846
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 817-846
    • Bass, B.L.1
  • 128
    • 22144444302 scopus 로고    scopus 로고
    • The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage
    • adjs@bioc.cam.ac.uk
    • A DJ Scadden adjs@bioc.cam.ac.uk The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage. Nature Structural and Molecular Biology 12 6 2005 489 496
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.6 , pp. 489-496
    • Scadden, A.D.J.1
  • 129
    • 30044443191 scopus 로고    scopus 로고
    • Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
    • W Yang T P Chendrimada Q Wang Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nature Structural and Molecular Biology 13 1 2006 13 21
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.1 , pp. 13-21
    • Yang, W.1    Chendrimada, T.P.2    Wang, Q.3
  • 130
    • 3342969381 scopus 로고    scopus 로고
    • RNA editing of a miRNA precursor
    • smaas@lehigh.edu
    • D J Luciano H Mirsky N J Vendetti S Maas smaas@lehigh.edu RNA editing of a miRNA precursor. RNA 2004 10 8 1174 1177
    • (2004) RNA , vol.10 , Issue.8 , pp. 1174-1177
    • Luciano, D.J.1    Mirsky, H.2    Vendetti, N.J.3    Maas, S.4
  • 131
    • 0036810232 scopus 로고    scopus 로고
    • The role of RNA editing by ADARs in RNAi
    • S W Knight B L Bass The role of RNA editing by ADARs in RNAi. Molecular Cell 10 4 2002 809 817
    • (2002) Molecular Cell , vol.10 , Issue.4 , pp. 809-817
    • Knight, S.W.1    Bass, B.L.2
  • 132
    • 0035542769 scopus 로고    scopus 로고
    • RNAi is antagonized by A→I hyper-editing
    • A DJ Scadden C WJ Smith RNAi is antagonized by A→I hyper-editing. EMBO Reports 2 12 2001 1107 1111
    • (2001) EMBO Reports , vol.2 , Issue.12 , pp. 1107-1111
    • Scadden, A.D.J.1    Smith, C.W.J.2
  • 133
    • 27744581854 scopus 로고    scopus 로고
    • Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sites
    • A DJ Scadden M A O'Connell Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sites. Nucleic Acids Research 33 18 2005 5954 5964
    • (2005) Nucleic Acids Research , vol.33 , Issue.18 , pp. 5954-5964
    • Scadden, A.D.J.1    O'Connell, M.A.2
  • 135
    • 0037072660 scopus 로고    scopus 로고
    • Small RNAs correspond to centromere heterochromatic repeats
    • B J Reinhart D P Bartel Small RNAs correspond to centromere heterochromatic repeats. Science 297 5588 2002 1831
    • (2002) Science , vol.297 , Issue.5588 , pp. 1831
    • Reinhart, B.J.1    Bartel, D.P.2
  • 136
    • 10644221797 scopus 로고    scopus 로고
    • RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing
    • K I Noma T Sugiyama H Cam RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nature Genetics 36 11 2004 1174 1180
    • (2004) Nature Genetics , vol.36 , Issue.11 , pp. 1174-1180
    • Noma, K.I.1    Sugiyama, T.2    Cam, H.3
  • 137
    • 14844362869 scopus 로고    scopus 로고
    • RNA interference (RNAi)-dependent and RNAi-independent association of the Chp1 chromodomain protein with distinct heterochromatic loci in fission yeast
    • Janet.Partridge@stjude.org
    • V J Petrie J D Wuitschick C D Givens A M Kosinski J F Partridge Janet.Partridge@stjude.org RNA interference (RNAi)-dependent and RNAi-independent association of the Chp1 chromodomain protein with distinct heterochromatic loci in fission yeast. Molecular and Cellular Biology 25 6 2005 2331 2346
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.6 , pp. 2331-2346
    • Petrie, V.J.1    Wuitschick, J.D.2    Givens, C.D.3    Kosinski, A.M.4    Partridge, J.F.5
  • 138
    • 0029859275 scopus 로고    scopus 로고
    • Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function
    • karl@hgu.mrc.ac.uk
    • K Ekwall karl@hgu.mrc.ac.uk E R Nimmo J P Javerzat Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. Journal of Cell Science 109 11 1996 2637 2648
    • (1996) Journal of Cell Science , vol.109 , Issue.11 , pp. 2637-2648
    • Ekwall, K.1    Nimmo, E.R.2    Javerzat, J.P.3
  • 139
    • 0037370020 scopus 로고    scopus 로고
    • A uniform system for microRNA annotation
    • vambros@dartmouth.edu
    • V Ambros vambros@dartmouth.edu B Bartel D P Bartel A uniform system for microRNA annotation. RNA 9 3 2003 277 279
    • (2003) RNA , vol.9 , Issue.3 , pp. 277-279
    • Ambros, V.1    Bartel, B.2    Bartel, D.P.3
  • 140
    • 0842278323 scopus 로고    scopus 로고
    • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification
    • cburge@mit.edu
    • U Ohler S Yekta L P Lim D P Bartel C B Burge cburge@mit.edu Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. RNA 10 9 2004 1309 1322
    • (2004) RNA , vol.10 , Issue.9 , pp. 1309-1322
    • Ohler, U.1    Yekta, S.2    Lim, L.P.3    Bartel, D.P.4    Burge, C.B.5
  • 142
  • 143
    • 10644253787 scopus 로고    scopus 로고
    • Architecture of a validated microRNA: Target interaction
    • M C Vella K Reinert F J Slack Architecture of a validated microRNA: target interaction. Chemistry and Biology 11 12 2004 1619 1623
    • (2004) Chemistry and Biology , vol.11 , Issue.12 , pp. 1619-1623
    • Vella, M.C.1    Reinert, K.2    Slack, F.J.3
  • 144
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • B P Lewis C B Burge D P Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120 1 2005 15 20
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 145
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
    • X Xie J Lu E J Kulbokas Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 434 7031 2005 338 345
    • (2005) Nature , vol.434 , Issue.7031 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3
  • 148
    • 2442672918 scopus 로고    scopus 로고
    • A combined computational-experimental approach predicts human microRNA targets
    • M Kiriakidou P T Nelson A Kouranov A combined computational-experimental approach predicts human microRNA targets. Genes and Development 18 10 2004 1165 1178
    • (2004) Genes and Development , vol.18 , Issue.10 , pp. 1165-1178
    • Kiriakidou, M.1    Nelson, P.T.2    Kouranov, A.3
  • 149
    • 0942301280 scopus 로고    scopus 로고
    • The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR
    • frank.slack@yale.edu
    • M C Vella E Y Choi S Y Lin K Reinert F J Slack frank.slack@yale.edu The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR. Genes and Development 18 2 2004 132 137
    • (2004) Genes and Development , vol.18 , Issue.2 , pp. 132-137
    • Vella, M.C.1    Choi, E.Y.2    Lin, S.Y.3    Reinert, K.4    Slack, F.J.5
  • 150
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • lodish@wi.mit.edu
    • C Z Chen L Li H F Lodish lodish@wi.mit.edu D P Bartel MicroRNAs modulate hematopoietic lineage differentiation. Science 303 5654 2004 83 86
    • (2004) Science , vol.303 , Issue.5654 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 151
    • 0030970775 scopus 로고    scopus 로고
    • The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
    • E G Moss R C Lee V Ambros The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 88 5 1997 637 646
    • (1997) Cell , vol.88 , Issue.5 , pp. 637-646
    • Moss, E.G.1    Lee, R.C.2    Ambros, V.3
  • 152
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • B J Reinhart F J Slack M Basson The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403 6772 2000 901 906
    • (2000) Nature , vol.403 , Issue.6772 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3
  • 153
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • A E Pasquinelli B J Reinhart F J Slack Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408 6808 2000 86 89
    • (2000) Nature , vol.408 , Issue.6808 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.J.3
  • 154
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • F J Slack M Basson Z Liu V Ambros H R Horvitz G Ruvkun The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Molecular Cell 5 4 2000 659 669
    • (2000) Molecular Cell , vol.5 , Issue.4 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 155
    • 14644398601 scopus 로고    scopus 로고
    • The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans
    • H Großhans T Johnson K L Reinert M Gerstein F J Slack The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Developmental Cell 8 3 2005 321 330
    • (2005) Developmental Cell , vol.8 , Issue.3 , pp. 321-330
    • Großhans, H.1    Johnson, T.2    Reinert, K.L.3    Gerstein, M.4    Slack, F.J.5
  • 156
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • S M Johnson H Grosshans J Shingara RAS is regulated by the let-7 microRNA family. Cell 120 5 2005 635 647
    • (2005) Cell , vol.120 , Issue.5 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 157
    • 24144494563 scopus 로고    scopus 로고
    • The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    • A L Abbott E Alvarez-Saavedra E A Miska The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Developmental Cell 9 3 2005 403 414
    • (2005) Developmental Cell , vol.9 , Issue.3 , pp. 403-414
    • Abbott, A.L.1    Alvarez-Saavedra, E.2    Miska, E.A.3
  • 158
    • 0036670695 scopus 로고    scopus 로고
    • The bantam gene regulates Drosophila growth
    • D R Hipfner K Weigmann S M Cohen The bantam gene regulates Drosophila growth. Genetics 161 2002 4 1527 1537
    • (2002) Genetics , vol.161 , Issue.4 , pp. 1527-1537
    • Hipfner, D.R.1    Weigmann, K.2    Cohen, S.M.3
  • 159
    • 21244448730 scopus 로고    scopus 로고
    • Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development
    • D Leaman P Y Chen J Fak Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell 121 7 2005 1097 1108
    • (2005) Cell , vol.121 , Issue.7 , pp. 1097-1108
    • Leaman, D.1    Chen, P.Y.2    Fak, J.3
  • 160
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • krichevsky@cnd.bwh.harvard.edu
    • J A Chan A M Krichevsky krichevsky@cnd.bwh.harvard.edu K S Kosik MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Research 65 14 2005 6029 6033
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 164
    • 0346727383 scopus 로고    scopus 로고
    • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
    • arndt.borkhardt@paediat.med.uni-giessen.de
    • M Metzler M Wilda K Busch S Viehmann A Borkhardt arndt.borkhardt@paediat. med.uni-giessen.de High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes and Cancer 39 2 2004 167 169
    • (2004) Genes Chromosomes and Cancer , vol.39 , Issue.2 , pp. 167-169
    • Metzler, M.1    Wilda, M.2    Busch, K.3    Viehmann, S.4    Borkhardt, A.5
  • 165
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • L He J M Thomson M T Hemann A microRNA polycistron as a potential human oncogene. Nature 435 7043 2005 828 833
    • (2005) Nature , vol.435 , Issue.7043 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 166
    • 17644363376 scopus 로고    scopus 로고
    • A cellular microRNA mediates antiviral defense in human cells
    • charles.lecellier@infobiogen.fr
    • C-H Lecellier charles.lecellier@infobiogen.fr P Dunoyer K Arar A cellular microRNA mediates antiviral defense in human cells. Science 308 5721 2005 557 560
    • (2005) Science , vol.308 , Issue.5721 , pp. 557-560
    • Lecellier, C.-H.1    Dunoyer, P.2    Arar, K.3
  • 167
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • psarnow@stanford.edu
    • C L Jopling M Yi A M Lancaster S M Lemon P Sarnow psarnow@stanford.edu Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309 5740 2005 1577 1581
    • (2005) Science , vol.309 , Issue.5740 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 168
    • 27144558619 scopus 로고    scopus 로고
    • Targets for human encoded microRNAs in HIV genes
    • beenapillai@igib.res.in vinods@igib.res.in manoj@igib.res.in skb@igib.res.in
    • M Hariharan manoj@igib.res.in V Scaria vinods@igib.res.in B Pillai beenapillai@igib.res.in S K Brahmachari skb@igib.res.in Targets for human encoded microRNAs in HIV genes. Biochemical and Biophysical Research Communications 337 4 2005 1214 1218
    • (2005) Biochemical and Biophysical Research Communications , vol.337 , Issue.4 , pp. 1214-1218
    • Hariharan, M.1    Scaria, V.2    Pillai, B.3    Brahmachari, S.K.4
  • 169
    • 29344467120 scopus 로고    scopus 로고
    • A developmental timing microRNA and its target regulate life span in C. elegans
    • M Boehm F J Slack A developmental timing microRNA and its target regulate life span in C. elegans. Science 310 5756 2005 1954 1957
    • (2005) Science , vol.310 , Issue.5756 , pp. 1954-1957
    • Boehm, M.1    Slack, F.J.2
  • 171
    • 13444312098 scopus 로고    scopus 로고
    • Substrate requirements for let-7 function in the developing zebrafish embryo
    • plasterk@niob.knaw.nl
    • W P Kloosterman E Wienholds R F Ketting R HA Plasterk plasterk@niob.knaw.nl Substrate requirements for let-7 function in the developing zebrafish embryo. Nucleic Acids Research 32 21 2004 6284 6291
    • (2004) Nucleic Acids Research , vol.32 , Issue.21 , pp. 6284-6291
    • Kloosterman, W.P.1    Wienholds, E.2    Ketting, R.F.3    Plasterk, R.H.A.4
  • 172
    • 18244385475 scopus 로고    scopus 로고
    • MicroRNAs regulate brain morphogenesis in zebrafish
    • giraldez@saturn.med.nyu.edu
    • A J Giraldez giraldez@saturn.med.nyu.edu R M Cinalli M E Glasner MicroRNAs regulate brain morphogenesis in zebrafish. Science 308 5723 2005 833 838
    • (2005) Science , vol.308 , Issue.5723 , pp. 833-838
    • Giraldez, A.J.1    Cinalli, R.M.2    Glasner, M.E.3
  • 173
    • 22044458072 scopus 로고    scopus 로고
    • MicroRNA expression in zebrafish embryonic development
    • E Wienholds W P Kloosterman E Miska MicroRNA expression in zebrafish embryonic development. Science 309 5732 2005 310 311
    • (2005) Science , vol.309 , Issue.5732 , pp. 310-311
    • Wienholds, E.1    Kloosterman, W.P.2    Miska, E.3
  • 175
    • 28444491759 scopus 로고    scopus 로고
    • Analysis of the regulation of lin-41 during chick and mouse limb development
    • J J Lancman N C Caruccio B D Harfe Analysis of the regulation of lin-41 during chick and mouse limb development. Developmental Dynamics 234 4 2005 948 960
    • (2005) Developmental Dynamics , vol.234 , Issue.4 , pp. 948-960
    • Lancman, J.J.1    Caruccio, N.C.2    Harfe, B.D.3
  • 176
    • 28444475503 scopus 로고    scopus 로고
    • Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis
    • B RM Schulman A Esquela-Kerscher F J Slack Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Developmental Dynamics 234 4 2005 1046 1054
    • (2005) Developmental Dynamics , vol.234 , Issue.4 , pp. 1046-1054
    • Schulman, B.R.M.1    Esquela-Kerscher, A.2    Slack, F.J.3
  • 178
    • 0037145031 scopus 로고    scopus 로고
    • Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena
    • K Mochizuki N A Fine T Fujisawa M A Gorovsky Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena. Cell 110 6 2002 689 699
    • (2002) Cell , vol.110 , Issue.6 , pp. 689-699
    • Mochizuki, K.1    Fine, N.A.2    Fujisawa, T.3    Gorovsky, M.A.4
  • 179
    • 0038738781 scopus 로고    scopus 로고
    • RNA interference is required for normal centromere function in fission yeast
    • T Volpe V Schramke G L Hamilton RNA interference is required for normal centromere function in fission yeast. Chromosome Research 11 2 2003 137 146
    • (2003) Chromosome Research , vol.11 , Issue.2 , pp. 137-146
    • Volpe, T.1    Schramke, V.2    Hamilton, G.L.3
  • 180
    • 10644294519 scopus 로고    scopus 로고
    • The roles of histone modifications and small RNA in centromere function
    • K Ekwall The roles of histone modifications and small RNA in centromere function. Chromosome Research 12 6 2004 535 542
    • (2004) Chromosome Research , vol.12 , Issue.6 , pp. 535-542
    • Ekwall, K.1
  • 181
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • kmorris@coh.org
    • K V Morris kmorris@coh.org S W-L Chan S E Jacobsen D J Looney Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305 2004 5688 1289 1292
    • (2004) Science , vol.305 , Issue.5688 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.-L.2    Jacobsen, S.E.3    Looney, D.J.4
  • 182
    • 4544242851 scopus 로고    scopus 로고
    • Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
    • H Kawasaki K Taira Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 431 7005 2004 211 217
    • (2004) Nature , vol.431 , Issue.7005 , pp. 211-217
    • Kawasaki, H.1    Taira, K.2
  • 183
    • 0037418839 scopus 로고    scopus 로고
    • Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • cohen@embl.de
    • J Brennecke D R Hipfner A Stark R B Russell S M Cohen cohen@embl.de bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113 1 2003 25 36
    • (2003) Cell , vol.113 , Issue.1 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 184
    • 14844364472 scopus 로고    scopus 로고
    • Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
    • lford@ambion.com
    • A M Cheng M W Byrom J Shelton L P Ford lford@ambion.com Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Research 33 4 2005 1290 1297
    • (2005) Nucleic Acids Research , vol.33 , Issue.4 , pp. 1290-1297
    • Cheng, A.M.1    Byrom, M.W.2    Shelton, J.3    Ford, L.P.4
  • 186
    • 31944435282 scopus 로고    scopus 로고
    • Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma
    • J Kluiver E Haralambieva D de Jong Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma. Genes Chromosomes and Cancer 45 2 2006 147 153
    • (2006) Genes Chromosomes and Cancer , vol.45 , Issue.2 , pp. 147-153
    • Kluiver, J.1    Haralambieva, E.2    De Jong, D.3
  • 187
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Y Hayashita H Osada Y Tatematsu A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Research 65 21 2005 9628 9632
    • (2005) Cancer Research , vol.65 , Issue.21 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 188
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • jmendell@jhmi.edu
    • K A O'Donnell E A Wentzel K I Zeller C V Dang J T Mendell jmendell@jhmi.edu c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435 7043 2005 839 843
    • (2005) Nature , vol.435 , Issue.7043 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4    Mendell, J.T.5
  • 190
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • nevin001@mc.duke.edu
    • G Leone J DeGregori R Sears L Jakoi J R Nevins nevin001@mc.duke.edu Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387 6631 1997 422 426
    • (1997) Nature , vol.387 , Issue.6631 , pp. 422-426
    • Leone, G.1    Degregori, J.2    Sears, R.3    Jakoi, L.4    Nevins, J.R.5
  • 192
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • J Takamizawa H Konishi K Yanagisawa Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Research 64 11 2004 3753 3756
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 193
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • Y Karube H Tanaka H Osada Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Science 96 2 2005 111 115
    • (2005) Cancer Science , vol.96 , Issue.2 , pp. 111-115
    • Karube, Y.1    Tanaka, H.2    Osada, H.3
  • 195
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • J Lu G Getz E A Miska MicroRNA expression profiles classify human cancers. Nature 435 7043 2005 834 838
    • (2005) Nature , vol.435 , Issue.7043 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 196
    • 27244433702 scopus 로고    scopus 로고
    • Real-time expression profiling of microRNA precursors in human cancer cell lines
    • schmittgen.2@osu.edu
    • J Jiang E J Lee Y Gusev T D Schmittgen schmittgen.2@osu.edu Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Research 33 17 2005 5394 5403
    • (2005) Nucleic Acids Research , vol.33 , Issue.17 , pp. 5394-5403
    • Jiang, J.1    Lee, E.J.2    Gusev, Y.3    Schmittgen, T.D.4
  • 197
    • 4644242349 scopus 로고    scopus 로고
    • RNA silencing in plants
    • D Baulcombe RNA silencing in plants. Nature 431 7006 2004 356 363
    • (2004) Nature , vol.431 , Issue.7006 , pp. 356-363
    • Baulcombe, D.1
  • 199
    • 2342420041 scopus 로고    scopus 로고
    • Identification of virus-encoded microRNAs
    • S Pfeffer M Zavolan F A Grässer Identification of virus-encoded microRNAs. Science 304 5671 2004 734 736
    • (2004) Science , vol.304 , Issue.5671 , pp. 734-736
    • Pfeffer, S.1    Zavolan, M.2    Grässer, F.A.3
  • 202
    • 14744284227 scopus 로고    scopus 로고
    • HIV-1 nef suppression by virally encoded microRNA
    • shin@snow.odn.ne.jp shinyaomoto@hotmail.com tsutsumi@fugita-hu.ac.jp
    • S Omoto shinyaomoto@hotmail.com M Ito shin@snow.odn.ne.jp Y Tsutsumi tsutsumi@fugita-hu.ac.jp HIV-1 nef suppression by virally encoded microRNA. Retrovirology 1 2004 44
    • (2004) Retrovirology , vol.1 , pp. 44
    • Omoto, S.1    Ito, M.2    Tsutsumi, Y.3
  • 203
    • 14744297918 scopus 로고    scopus 로고
    • Regulation of human immunodeficiency virus 1 transcription by nef microRNA
    • fatfuji@hotmail.com
    • S Omoto Y R Fujii fatfuji@hotmail.com Regulation of human immunodeficiency virus 1 transcription by nef microRNA. Journal of General Virology 86 3 2005 751 755
    • (2005) Journal of General Virology , vol.86 , Issue.3 , pp. 751-755
    • Omoto, S.1    Fujii, Y.R.2
  • 204
    • 19344370167 scopus 로고    scopus 로고
    • Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing
    • kj7e@nih.gov
    • Y Bennasser S-Y Le M Benkirane K-T Jeang kj7e@nih.gov Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing. Immunity 22 5 2005 607 619
    • (2005) Immunity , vol.22 , Issue.5 , pp. 607-619
    • Bennasser, Y.1    Le S, -Y.2    Benkirane, M.3    Jeang, K.-T.4
  • 205
    • 20444446357 scopus 로고    scopus 로고
    • SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells
    • ganem@cgl.ucsf.edu
    • C S Sullivan A T Grundhoff S Tevethia J M Pipas D Ganem ganem@cgl.ucsf.edu SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature 435 7042 2005 682 686
    • (2005) Nature , vol.435 , Issue.7042 , pp. 682-686
    • Sullivan, C.S.1    Grundhoff, A.T.2    Tevethia, S.3    Pipas, J.M.4    Ganem, D.5


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