Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs

Journal of Biomedicine and Biotechnology

Volumn 2006, Issue , 2006, Pages

  Plante, Isabelle ^a,b   Davidovic, Laetitia ^a,b   Ouellet, Dominique L ^a,b   Gobeil, Lise Andrée ^a,b   Tremblay, Sandra ^a,b   Khandjian, Edouard W ^a,b   Provost, Patrick ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; MICRORNA; RECOMBINANT PROTEIN; RIBONUCLEASE; RNA; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; TRANSFER RNA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FRAGILE X SYNDROME; GENE SILENCING; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; RNA INTERFERENCE; RNA SEQUENCE; SEQUENCE HOMOLOGY;

MAMMALIA;

EID: 33746852731     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/JBB/2006/64347     Document Type: Article

References (62)

1. D P Bartel dbartel@wi.mit.edu MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 2 2004 281 297
2. Y Lee M Kim J Han MicroRNA genes are transcribed by RNA polymerase II. EMBO Journal 23 20 2004 4051 4060
3. Y Lee C Ahn J Han The nuclear RNase III Drosha initiates microRNA processing. Nature 425 6956 2003 415 419
4. R Yi Y Qin I G Macara B R Cullen culle002@mc.duke.edu Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes and Development 17 24 2003 3011 3016
5. E Bernstein A A Caudy S M Hammond G J Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 6818 2001 363 366
6. P Provost D Dishart J Doucet D Frendewey B Samuelsson O Radmark Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO Journal 21 21 2002 5864 5874
7. H Zhang F A Kolb V Brondani E Billy W Filipowicz Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO Journal 21 21 2002 5875 5885
8. H Zhang F A Kolb L Jaskiewicz E Westhof W Filipowicz filipowi@fmi.ch Single processing center models for human Dicer and bacterial RNase III. Cell 118 1 2004 57 68
9. D S Schwarz G Hutvágner T Du Z Xu N Aronin P D Zamore phillip.zamore@umassmed.edu Asymmetry in the assembly of the RNAi enzyme complex. Cell 115 2 2003 199 208
10. S M Hammond E Bernstein D Beach G J Hannon hannon@cshl.org An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404 6775 2000 293 296
11. L P Lim N C Lau E G Weinstein The microRNAs of Caenorhabditis elegans. Genes and Development 17 8 2003 991 1008
12. B J Reinhart E G Weinstein M W Rhoades B Bartel D P Bartel MicroRNAs in plants. Genes and Development 16 13 2002 1616 1626
13. M Lagos-Quintana R Rauhut W Lendeckel T Tuschl Identification of novel genes coding for small expressed RNAs. Science 294 5543 2001 853 858
14. N C Lau L P Lim E G Weinstein D P Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294 5543 2001 858 862
15. R C Lee V Ambros An extensive class of small RNAs in Caenorhabditis elegans. Science 294 5543 2001 862 864
16. S Pfeffer M Zavolan F A Grässer Identification of virus-encoded microRNAs. Science 304 5671 2004 734 736
17. B J Reinhart F J Slack M Basson The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403 6772 2000 901 906
18. S Yekta I-H Shih D P Bartel MicroRNA-directed cleavage of HOXB8 mRNA. Science 304 5670 2004 594 596
19. R S Pillai S N Bhattacharyya C G Artus Inhibition of translational initiation by let-7 microRNA in human cells. Science 309 5740 2005 1573 1576
20. W T O'Donnell S T Warren A decade of molecular studies of fragile X syndrome. Annual Review of Neuroscience 25 2002 315 338
21. B Bardoni J-L Mandel Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes. Current Opinion in Genetics and Development 12 3 2002 284 293
22. B Laggerbauer D Ostareck E-M Keidel A Ostareck-Lederer U Fischer Evidence that fragile X mental retardation protein is a negative regulator of translation. Human Molecular Genetics 10 4 2001 329 338
23. Z Li Y Zhang L Ku K D Wilkinson S T Warren Y Feng The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Research 29 11 2001 2276 2283
24. R Mazroui M E Hout S Tremblay C Fillion Y Labelle E W Khandjian Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression. Human Molecular Genetics 11 24 2002 3007 3017
25. A Costa Y Wang T C Dockendorff The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway. Developmental Cell 8 3 2005 331 342
26. Y Q Zhang A M Bailey H JG Matthies Drosophila fragile x-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 107 5 2001 591 603
27. A A Caudy M Myers G J Hannon S M Hammond Fragile X-related protein and VIG associate with the RNA interference machinery. Genes and Development 16 19 2002 2491 2496
28. A Ishizuka M C Siomi H Siomi A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes and Development 16 19 2002 2497 2508
29. P Jin D C Zarnescu S Ceman Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nature Neuroscience 7 2 2004 113 117
30. R Mazroui M-E Huot S Tremblay N Boilard Y Labelle E W Khandjian Fragile X mental retardation protein determinants required for its association with polyribosomal mRNPs. Human Molecular Genetics 12 23 2003 3087 3096
31. E W Khandjian Biology of the fragile X mental retardation protein, an RNA-binding protein. Biochemistry and Cell Biology 77 4 1999 331 342
32. C Gabus R Mazroui S Tremblay E W Khandjian J-L Darlix jldarlix@ens-lyon.fr The fragile X mental retardation protein has nucleic acid chaperone properties. Nucleic Acids Research 32 7 2004 2129 2137
33. M Castets C Schaeffer E Bechara FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts. Human Molecular Genetics 14 6 2005 835 844
34. D Devys Y Lutz N Rouyer J-P Bellocq J-L Mandel The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nature Genetics 4 4 1993 335 340
35. J C Darnell darneje@rockefeller.edu O Mostovetsky R B Darnell FMRP RNA targets: identification and validation. Genes, Brain and Behavior 4 6 2005 341 349
36. E W Khandjian E Bechara L Davidovic B Bardoni bardoni@unice.fr Fragile X mental retardation protein: many partners and multiple targets for a promiscuous function. Current Genomics 6 7 2005 515 522
37. K De Boulle A JMH Verkerk E Reyniers A point mutation in the FMR-1 gene associated with fragile X mental retardation. Nature Genetics 3 1 1993 31 35
38. R Singh rsingh@colorado.edu J Valcárcel Building specificity with nonspecific RNA-binding proteins. Nature Structural and Molecular Biology 12 8 2005 645 653
39. R Yi B P Doehle Y Qin I G Macara B R Cullen Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA 11 2 2005 220 226
40. J Harborth S M Elbashir K Vandenburgh Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense and Nucleic Acid Drug Development 13 2 2003 83 105
41. P Oberdoerffer philober@hms.harvard.edu C Kanellopoulou V Heissmeyer Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages. Molecular and Cellular Biology 25 10 2005 3896 3905
42. J Martinez A Patkaniowska H Urlaub R Lührmann T Tuschl Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 5 2002 563 574
43. D S Schwarz G Hutvágner B Haley P D Zamore Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Molecular Cell 10 3 2002 537 548
44. J W Pham J L Pellino Y S Lee R W Carthew E J Sontheimer erik@northwestern.edu A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117 1 2004 83 94
45. Y Tomari T Du B Haley RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116 6 2004 831 841
46. Y S Lee K Nakahara J W Pham Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117 1 2004 69 81
47. N Tahbaz F A Kolb H Zhang K Jaronczyk W Filipowicz T C Hobman tom.hobman@ualberta.ca Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. EMBO Reports 5 2 2004 189 194
48. R I Gregory T P Chendrimada N Cooch R Shiekhattar shiekhattar@wistar.org Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123 4 2005 631 640
49. Y Feng D Absher D E Eberhart V Brown H E Malter S T Warren swarren@bimcore.emory.edu FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. Molecular Cell 1 1 1997 109 118
50. P Jin R S Alisch S T Warren swarren@emory.edu RNA and microRNAs in fragile X mental retardation. Nature Cell Biology 6 11 2004 1048 1053
51. J C Darnell K B Jensen P Jin V Brown S T Warren R B Darnell Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 107 4 2001 489 499
52. C Schaeffer B Bardoni J-L Mandel B Ehresmann C Ehresmann H Moine The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. EMBO Journal 20 17 2001 4803 4813
53. J C Darnell C E Fraser O Mostovetsky Kissing complex RNAs mediate interaction between the fragile-X mental retardation protein KH2 domain and brain polyribosomes. Genes and Development 19 8 2005 903 918
54. J C Darnell darneie@rockefeller.edu S T Warren R B Darnell The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10 1 2004 49 52
55. V Brown P Jin S Ceman Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 107 4 2001 477 487
56. D E Eberhart H E Malter Y Feng S T Warren The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Human Molecular Genetics 5 8 1996 1083 1091
57. Y Feng C-A Gutekunst D E Eberhart H Yi S T Warren S M Hersch Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. Journal of Neuroscience 17 5 1997 1539 1547
58. L N Antar R Afroz J B Dictenberg R C Carroll G J Bassell bassell@aecom.yu.edu Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. Journal of Neuroscience 24 11 2004 2648 2655
59. Z Mourelatos J Dostie S Paushkin miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes and Development 16 6 2002 720 728
60. J Kim A Krichevsky Y Grad Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proceedings of the National Academy of Sciences of the United States of America 101 1 2004 360 365
61. J R Kennerdell S Yamaguchi R W Carthew RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes and Development 16 15 2002 1884 1889
62. E W Khandjian A Fortin A Thibodeau A heterogeneous set of FMR1 proteins is widely distributed in mouse tissues and is modulated in cell culture. Human Molecular Genetics 4 5 1995 783 789