A cellular microRNA mediates antiviral defense in human cells

Science

Volumn 308, Issue 5721, 2005, Pages 557-560

  Lecellier, Charles Henri ^a   Dunoyer, Patrice ^a   Arar, Khalil ^b   Lehmann Che, Jacqueline ^c   Eyquem, Stephanie ^c   Himber, Christophe ^a   Saïb, Ali ^c   Voinnet, Olivier ^a  

^a INST DE BIOL MOLEC DES PLANTES   (France)

^b Proligo   (France)

^c SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; GENE TRANSFER; NUCLEIC ACIDS; PLANTS (BOTANY); PROTEINS; VIRUSES;

EUKARYOTES; HUMAN CELLS; MAMMALIAN CELLS; REGULATORY FUNCTIONS;

RNA;

MICRORNA; NUCLEIC ACID; VIRUS PROTEIN;

BIOCHEMISTRY;

ANTIVIRAL ACTIVITY; ARTICLE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETROVIRUS; RNA REPLICATION; SPUMA VIRUS; VIRUS GENOME;

ANIMALS; ANTIVIRAL AGENTS; ARABIDOPSIS; CELL LINE; CRICETINAE; DNA-BINDING PROTEINS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; MICRORNAS; OLIGONUCLEOTIDES, ANTISENSE; PLANTS, GENETICALLY MODIFIED; PROTEIN BIOSYNTHESIS; RETROVIRIDAE PROTEINS; RNA INTERFERENCE; RNA, VIRAL; SPUMAVIRUS; TRANS-ACTIVATORS; TRANSFECTION; VIRUS REPLICATION;

EUKARYOTA; HEXAPODA; HUMAN SPUMARETROVIRUS; MAMMALIA; PRIMATES; UNIDENTIFIED RETROVIRUS;

EID: 17644363376     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1108784     Document Type: Article

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23. We thank S. W. Ding, B. Cullen, and P. Zamore for critical reading of the manuscript and access to data; members of the Voinnet lab for discussions; and R. Wagner's team for excellent plant care. Supported by an Action Thématique Incitative sur Programme from the CNRS, the Fondation pour la Recherche Médicale, and the Université Louis Pasteur, Strasbourg.