A protein sensor for siRNA asymmetry

Science

Volumn 306, Issue 5700, 2004, Pages 1377-1380

  Tomari, Yukihide ^a   Matranga, Christian ^a   Haley, Benjamin ^a   Martinez, Natalia ^a   Zamore, Phillip D ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; PROTEINS; SENSORS; THERMODYNAMICS;

CLEAVAGE; PROTEIN SENSORS; RNA-INDUCED SILENCING COMPLEX (RISC);

RNA;

ARGONAUTE 2 PROTEIN; DICER 2 PROTEIN; DOUBLE STRANDED RNA; MESSENGER RNA; PROTEIN; R2D2 PROTEIN; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

RNA;

ARTICLE; BASE PAIRING; DROSOPHILA; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA DEGRADATION; RNA INTERFERENCE; RNA STABILITY; RNA STRUCTURE; SENSOR; THERMODYNAMICS;

ANIMALS; DIMERIZATION; DROSOPHILA; DROSOPHILA PROTEINS; LIGHT; LUCIFERASES; NUCLEIC ACID CONFORMATION; RNA HELICASES; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; RNA-INDUCED SILENCING COMPLEX; SUPEROXIDE DISMUTASE; THERMODYNAMICS; URACIL;

EID: 8844271740     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1102755     Document Type: Article

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26. We thank D. Turner, C. R. Matthews, Z. Gu, and members of the Zamore laboratory for advice and support, and Q. Liu, G. Hannon, T. Uemura, D. Smith, R. Carthew, M. Siomi, and H. Siomi for gifts of reagents. Y.T. is a recipient of a long-term fellowship from the Human Frontier Science Program. P.D.Z. is a Pew Scholar in the Biomedical Sciences and a W. M. Keck Foundation Young Scholar in Medical Research. Supported by NIH grants GM62862-01 and GM65236-01 (P.D.Z.).