Structural basis for 5′ -end-specific recognition of guide RNA by the A. fulgidus Piwi protein

Nature

Volumn 434, Issue 7033, 2005, Pages 666-670

  Ma, Jin Biao ^a   Yuan, Yu Ren ^a   Meister, Gunter ^b   Pei, Yi ^b   Tuschl, Thomas ^b   Patel, Dinshaw J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; GENES; NUCLEATION; POSITIVE IONS; PROTEINS;

ARGONAUTE PROTEINS; DIVALENT CATIONS; RNA INTERFERENCE; TARGET RECOGNITION;

RNA;

AGO2 PROTEIN; ARGONAUTE PROTEIN; BACTERIAL PROTEIN; MESSENGER RNA; MUTANT PROTEIN; PIWI PROTEIN; RIBONUCLEASE H; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ARCHAEAL PROTEIN; DOUBLE STRANDED RNA; EUKARYOTIC INITIATION FACTOR 2C 2, HUMAN; EUKARYOTIC INITIATION FACTOR 2C-2, HUMAN; GUIDE RNA; INITIATION FACTOR; PHOSPHATE;

RNA;

ARCHAEOGLOBUS FULGIDUS; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; GENE MUTATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN RNA BINDING; RNA INTERFERENCE; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; ARCHAEOGLOBUS FULGIDUS; BASE SEQUENCE; BINDING SITES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PEPTIDE INITIATION FACTORS; PHOSPHATES; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, GUIDE; RNA, MESSENGER; SUBSTRATE SPECIFICITY;

EID: 15844371219     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03514     Document Type: Article

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