-
1
-
-
0036301947
-
A decade of molecular studies of fragile X syndrome
-
O'Donnell, W.T. & Warren, S.T. A decade of molecular studies of fragile X syndrome. Annu. Rev. Neurosci. 25, 315-338 (2002).
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 315-338
-
-
O'Donnell, W.T.1
Warren, S.T.2
-
2
-
-
0029069223
-
FXR1, an autosomal homolog of the fragile X mental retardation gene
-
Siomi, M.C. et al. FXR1, an autosomal homolog of the fragile X mental retardation gene. Embo J. 14, 2401-2408 (1995).
-
(1995)
Embo J.
, vol.14
, pp. 2401-2408
-
-
Siomi, M.C.1
-
3
-
-
0028971722
-
The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2
-
Zhang, Y. et al. The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2, Embo J. 14, 5358-5366 (1995).
-
(1995)
Embo J.
, vol.14
, pp. 5358-5366
-
-
Zhang, Y.1
-
4
-
-
0035368955
-
The fragile X mental retardation protein inhibits translation via interacting with mRNA
-
Li, Z. et al. The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Res. 29, 2276-2283 (2001).
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2276-2283
-
-
Li, Z.1
-
5
-
-
0035864826
-
Evidence that fragile X mental retardation protein is a negative regulator of translation
-
Laggerbauer, B., Ostareck, D., Keidel, E.M., Ostareck-Lederer, A. & Fischer, U. Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum. Mol. Genet. 10, 329-338 (2001).
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 329-338
-
-
Laggerbauer, B.1
Ostareck, D.2
Keidel, E.M.3
Ostareck-Lederer, A.4
Fischer, U.5
-
6
-
-
0030986183
-
Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
-
Comery, T.A. et al. Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits, Proc. Natl. Acad. Sci. USA 94, 5401-5404 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5401-5404
-
-
Comery, T.A.1
-
7
-
-
0025720084
-
Analysis of neocortex in three males with the fragile X syndrome
-
Hinton, V.J., Brown, W.T., Wisniewski, K. & Rudelli, R.D. Analysis of neocortex in three males with the fragile X syndrome. Am. J. Med. Genet. 41, 289-294 (1991).
-
(1991)
Am. J. Med. Genet.
, vol.41
, pp. 289-294
-
-
Hinton, V.J.1
Brown, W.T.2
Wisniewski, K.3
Rudelli, R.D.4
-
8
-
-
0035879180
-
Abnormal development of dendritic spines in FMR1 knock-out mice
-
Nimchinsky, E.A., Oberlander, A.M. & Svoboda, K. Abnormal development of dendritic spines in FMR1 knock-out mice. J. Neurosci. 21, 5139-5146 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5139-5146
-
-
Nimchinsky, E.A.1
Oberlander, A.M.2
Svoboda, K.3
-
9
-
-
0031046778
-
Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes
-
Feng, Y. et al. Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci. 17, 1539-1547 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 1539-1547
-
-
Feng, Y.1
-
10
-
-
0036591664
-
Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes
-
Bardoni, B. & Mandel, J.L. Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes. Curr. Opin. Genet. Dev. 12, 284-293 (2002).
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 284-293
-
-
Bardoni, B.1
Mandel, J.L.2
-
11
-
-
0037188502
-
Altered synaptic plasticity in a mouse model of fragile X mental retardation
-
Huber, K.M., Gallagher, S.M., Warren, S.T. & Bear, M.F. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad. Sci. USA 99, 7746-7750 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7746-7750
-
-
Huber, K.M.1
Gallagher, S.M.2
Warren, S.T.3
Bear, M.F.4
-
12
-
-
0035801393
-
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
-
Schaeffer, C. et al. The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. Embo J. 20, 4803-4813 (2001).
-
(2001)
Embo J.
, vol.20
, pp. 4803-4813
-
-
Schaeffer, C.1
-
13
-
-
18044379515
-
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome
-
Brown, V. et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 107, 477-487 (2001).
-
(2001)
Cell
, vol.107
, pp. 477-487
-
-
Brown, V.1
-
14
-
-
0035900649
-
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
-
Darnell, J.C. et al. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 107, 489-499 (2001).
-
(2001)
Cell
, vol.107
, pp. 489-499
-
-
Darnell, J.C.1
-
15
-
-
0037421721
-
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr 1 null mice
-
Miyashiro, K.Y. et al. RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 37, 417-431 (2003).
-
(2003)
Neuron
, vol.37
, pp. 417-431
-
-
Miyashiro, K.Y.1
-
16
-
-
0038797997
-
The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo
-
Sung, Y.J. et al. The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo. J. Biol. Chem. 278, 15669-15678 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15669-15678
-
-
Sung, Y.J.1
-
17
-
-
0037423293
-
The fragile X syndrome protein FMRP associates with BC 1 RNA and regulates the translation of specific mRNAs at synapses
-
Zalfa, F. et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses. Cell 112, 317-327 (2003).
-
(2003)
Cell
, vol.112
, pp. 317-327
-
-
Zalfa, F.1
-
18
-
-
0347382502
-
Phosphorylation influences the translation state of FMRP-associated polyribosomes
-
Ceman, S. et al. Phosphorylation influences the translation state of FMRP-associated polyribosomes. Hum. Mol. Genet. 12, 3295-3305 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3295-3305
-
-
Ceman, S.1
-
19
-
-
0037213225
-
RNA interference: Traveling in the cell and gaining functions?
-
Cerutti, H. RNA interference: traveling in the cell and gaining functions? Trends Genet. 19, 39-46 (2003).
-
(2003)
Trends Genet.
, vol.19
, pp. 39-46
-
-
Cerutti, H.1
-
20
-
-
0035261255
-
Post-transcriptional gene silencing by double-stranded RNA
-
Hammond, S.M., Caudy, A.A. & Hannon, G.J. Post-transcriptional gene silencing by double-stranded RNA. Nat. Rev. Genet. 2, 110-119 (2001).
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 110-119
-
-
Hammond, S.M.1
Caudy, A.A.2
Hannon, G.J.3
-
21
-
-
0036437372
-
Control of developmental timing by microRNAs and their targets
-
Pasquinelli, A.E. & Ruvkun, G. Control of developmental timing by microRNAs and their targets. Annu. Rev. Cell Dev. Biol. 18, 495-513 (2002).
-
(2002)
Annu. Rev. Cell Dev. Biol.
, vol.18
, pp. 495-513
-
-
Pasquinelli, A.E.1
Ruvkun, G.2
-
22
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus, M.T. & Sharp, P.A. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3, 737-747 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
23
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E., Caudy, A.A., Hammond, S.M. & Hannon, G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366 (2001).
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
24
-
-
0036828639
-
The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
-
Carmell, M.A., Xuan, Z., Zhang, M.Q. & Hannon, G.J. The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16, 2733-2742 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2733-2742
-
-
Carmell, M.A.1
Xuan, Z.2
Zhang, M.Q.3
Hannon, G.J.4
-
25
-
-
0036791671
-
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
-
Ishizuka, A., Siomi, M.C. & Siomi, H. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev. 16, 2497-2508 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2497-2508
-
-
Ishizuka, A.1
Siomi, M.C.2
Siomi, H.3
-
26
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy, A.A., Myers, M., Hannon, G.J. & Hammond, S.M. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16, 2491-2496 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2491-2496
-
-
Caudy, A.A.1
Myers, M.2
Hannon, G.J.3
Hammond, S.M.4
-
27
-
-
0037333288
-
New insights into fragile X syndrome: From molecules to neurobehaviors
-
Jin, P. & Warren, S.T. New insights into fragile X syndrome: from molecules to neurobehaviors. Trends Biochem. Sci. 28, 152-158 (2003).
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 152-158
-
-
Jin, P.1
Warren, S.T.2
-
28
-
-
0035839109
-
Argonaute 2, a link between genetic and biochemical analyses of RNAi
-
Hammond, S.M., Boettcher, S., Caudy, A.A., Kobayashi, R. & Hannon, G.J. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293, 1146-1150 (2001).
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
29
-
-
0037087780
-
miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos, Z. et al. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16, 720-728 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
-
30
-
-
0036501460
-
Knockout mouse model for Fxr2: A model for mental retardation
-
Bontekoe, C.J. et al. Knockout mouse model for Fxr2: a model for mental retardation. Hum. Mol. Genet. 11, 487-498 (2002).
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 487-498
-
-
Bontekoe, C.J.1
-
31
-
-
0028246435
-
Fmr1 knockout mice: A model to study fragile X mental retardation
-
The Dutch-Belgian Fragile X Consortium. Fmr1 knockout mice: a model to study fragile X mental retardation. Cell 78, 23-33 (1994).
-
(1994)
Cell
, vol.78
, pp. 23-33
-
-
-
32
-
-
0037425583
-
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and elF 2C translation initiation factors
-
Doi, N. et al. Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and elF2C translation initiation factors. Curr. Biol. 13, 41-46 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 41-46
-
-
Doi, N.1
-
33
-
-
0033761489
-
Characterization of dFMR 1, a Drosophila melanogaster homolog of the fragile X mental retardation protein
-
Wan, L., Dockendorff, T.C., Jongens, T.A. & Dreyfuss, G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Mol. Cell. Biol. 20, 8536-8547 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8536-8547
-
-
Wan, L.1
Dockendorff, T.C.2
Jongens, T.A.3
Dreyfuss, G.4
-
34
-
-
0035977134
-
Drosophila fragile X-related gene regulates the MAP 1B homolog Futsch to control synaptic structure and function
-
Zhang, Y.Q. et al. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 107, 591-603 (2001).
-
(2001)
Cell
, vol.107
, pp. 591-603
-
-
Zhang, Y.Q.1
-
35
-
-
0037076320
-
ARGONAUTE 1 is required for efficient RNA interference in Drosophila embryos
-
Williams, R.W. & Rubin, G.M. ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc. Natl. Acad. Sci. USA 99, 6889-6894 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6889-6894
-
-
Williams, R.W.1
Rubin, G.M.2
-
36
-
-
0035043250
-
Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonautel, the founder of a novel gene superfamily
-
Kataoka, Y., Takeichi, M. & Uemura, T. Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonautel, the founder of a novel gene superfamily. Genes Cells 6, 313-325 (2001).
-
(2001)
Genes Cells
, vol.6
, pp. 313-325
-
-
Kataoka, Y.1
Takeichi, M.2
Uemura, T.3
-
37
-
-
0037071905
-
Drosophila lacking dfmr 1 activity show defects in circadian output and fail to maintain courtship interest
-
Dockendorff, T.C. et al. Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest. Neuron 34, 973-984 (2002).
-
(2002)
Neuron
, vol.34
, pp. 973-984
-
-
Dockendorff, T.C.1
-
39
-
-
0037456560
-
Sunrise at the synapse: The FMRP mRNP shaping the synaptic interface
-
Antar, L.N. & Bassell, G.J. Sunrise at the synapse: the FMRP mRNP shaping the synaptic interface. Neuron 37, 555-558 (2003).
-
(2003)
Neuron
, vol.37
, pp. 555-558
-
-
Antar, L.N.1
Bassell, G.J.2
|