Purified Argonaute2 and an siRNA form recombinant human RISC

Nature Structural and Molecular Biology

Volumn 12, Issue 4, 2005, Pages 340-349

  Rivas, Fabiola V ^a   Tolia, Niraj H ^a,b   Song, Ji Joon ^a,b   Aragon, Juan P ^a   Liu, Jidong ^a   Hannon, Gregory J ^a   Joshua Tor, Leemor ^a,b  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b W M Keck Structural Biology Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ASPARTIC ACID; HISTIDINE; MUTANT PROTEIN; PROTEIN ARGONAUTE2; RECOMBINANT ENZYME; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; EUKARYOTIC INITIATION FACTOR 2C 2, HUMAN; EUKARYOTIC INITIATION FACTOR 2C-2, HUMAN; INITIATION FACTOR; PHOSPHATE; RECOMBINANT PROTEIN; RIBONUCLEASE H; RNA INDUCED SILENCING COMPLEX;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PURIFICATION; RNA INTERFERENCE; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; X RAY CRYSTALLOGRAPHY;

DROSOPHILA MELANOGASTER;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA MELANOGASTER; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE INITIATION FACTORS; PHOSPHATES; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RIBONUCLEASE H, CALF THYMUS; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 18744407284     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb918     Document Type: Article

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