The roles of histone modifications and small RNA in centromere function

Chromosome Research

Volumn 12, Issue 6, 2004, Pages 535-542

  Ekwall, Karl ^a,b  

^a SÖDERTÖRN UNIVERSITY   (Sweden)

^b NONE   (Sweden)

Author keywords

Centromere; Chromatin; Fission yeast; Histone; RNA interference

Indexed keywords

ARGONAUTE PROTEIN; COHESIN; DICER; FUNGAL PROTEIN; GENE PRODUCT; HISTONE; HISTONE DEACETYLASE; METHYLTRANSFERASE; PROTEIN SWI6; RIBONUCLEASE; RNA; RNA DIRECTED RNA POLYMERASE; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CENTROMERE; CHROMATID; FUNGAL GENETICS; HETEROCHROMATIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RNA INTERFERENCE; SCHIZOSACCHAROMYCES POMBE; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE;

CENTROMERE; HISTONES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA INTERFERENCE; RNA, SMALL INTERFERING; SCHIZOSACCHAROMYCES;

EID: 10644294519     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CHRO.0000036584.40567.e5     Document Type: Article

References (52)

1. Allshire RC, Nimmo ER, Ekwall K et al. (1995) Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev 9: 218-233.
2. Appelgren H, Kniola B, Ekwall K (2003) Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells. J Cell Sci 116: 4035-4042.
3. Bannister AJ, Zegerman P, Partridge JF et al. (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410: 120-124.
4. Bernard P, Maure JF, Partridge JF et al. (2001) Requirement of heterochromatin for cohesion at centromeres. Science 11: 11.
5. Bernstein E, Caudy AA, Hammond SM et al. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366.
6. Bjerling P, Silverstein RA, Thon G et al. (2002) Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity. Mol Cell Biol 22: 2170-2181.
7. Carbon J, Clarke L (1990) Centromere structure and function in budding and fission yeasts. New Biol 2: 10-19.
8. Chen ES, Saitoh S, Yanagida M et al. (2003a) A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast. Mol Cell 11: 175-187.
9. Chen ES, Yanagida M, Takahashi K (2003b) Does a GATA factor make the bed for centromeric nucleosomes? Cell Cycle 2: 277-278.
10. Chikashige Y, Kinoshita N, Nakaseko Y et al. (1989) Composite motifs and repeat symmetry in S. pombe centromeres: direct analysis by integration of NotI restriction sites. Cell 57: 739-751.
11. Clarke L, Baum MP (1990) Functional analysis of a centromere from fission yeast: a role for centromere-specific repeated DNA sequences. Mol Cell Biol 10: 1863-1872.
12. Clarke L, Amstutz H, Fishel B et al. (1986) Analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci USA 83: 8253-8257.
13. Ekwall K, Javerzat JP, Lorentz A et al. (1995) The chromodomain protein Swi6: a key component at fission yeast centromeres. Science 269: 1429-1431.
14. Ekwall K, Nimmo ER, Javerzat JP et al (1996) Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. J Cell Sci 109: 2637-2648.
15. Ekwall, K, Olsson T, Turner BM et al. (1997) Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell 91: 1021-1032.
16. Ekwall K, Cranston G, Allshire RC (1999) Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation. Genetics 153: 1153-1169.
17. Fire A, Xu S, Montgomery MK et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
18. Funabiki H, Hagan I, Uzawa S et al. (1993) Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J Cell Biol 121: 961-976.
19. Garcia MA, Vardy L, Koonrugsa N et al. (2001) Fission yeast ch-TOG/XMAP215 homologue Alp 14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint. EMBO J 20: 3389-3401.
20. Hall IM, Noma K, Grewal SI (2003) RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc Natl Acad Sci USA 100: 193-198.
21. Hammond SM, Bernstein E, Beach D et al. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293-296.
22. Jin QW, Pidoux AL, Decker C et al. (2002) The mal2p protein is an essential component of the fission yeast centromere. Mol Cell Biol 22: 7168-7183.
23. Kniola B, O'Toole E, McIntosh JR et al. (2001) The domain structure of centromeres is conserved from fission yeast to humans. Mol Biol Cell 12: 2767-2775.
24. Lehnertz B, Ueda Y, Derijck AA et al. (2003) Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 13: 1192-1200.
25. Leverson JD, Huang HK, Forsburg SL et al. (2002) The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis. Mol Biol Cell 13: 1132-1143.
26. Mellone BG, Allshire RC (2003) Stretching it: putting the CEN(P-A) in centromere. Curr Opin Genet Dev 13: 191-198.
27. Mellone, BG, Ball L, Suka N et al. (2003) Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3. Curr Biol 13: 1748-1757.
28. Morishita J, Matsusaka T, Goshima G et al. (2001) Birl/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair. Genes Cells 6: 743-763.
29. Nakagawa H, Lee JK, Hurwitz J et al. (2002) Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. Genes Dev 16: 1766-1778.
30. Nakaseko Y, Goshima G, Morishita J et al. (2001) M phase-specific kinetochore proteins in fission yeast: microtubule-associating Dis1 and Mtc1 display rapid separation and segregation during anaphase. Curr Biol 11: 537-549.
31. Nakayama J, Rice JC, Strahl BD et al. (2001) Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292: 110-113.
32. Nakayama J, Xiao G, Noma K et al. (2003) Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity. EMBO J 22: 2776-2787.
33. Nonaka N, Kitajima T, Yokobayashi S et al. (2002) Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast. Nat Cell Biol 4: 89-93.
34. Partridge JF, Borgstrom B, Allshire RC (2000) Distinct protein interaction domains and protein spreading in a complex centromere. Genes Dev 14: 783-791.
35. Partridge JF, Scott KS, Bannister AJ et al. (2002) cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Curr Biol 12: 1652-1660.
36. Petersen J, Hagan IM (2003) S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response. Curr Biol 13: 590-597.
37. Petersen J, Paris J, Willer M et al. (2001) The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation. J Cell Sci 114: 4371-4384.
38. Pidoux, AL, Richardson W, Allshire RC (2003) Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation. J Cell Biol 161: 295-307.
39. Provost P, Silverstein RA, Walfridsson J et al. (2002) Dicer is required for chromosome segregation and gene silencing in fission yeast cells. P.N.A.S. 99: 16648-16653.
40. Rajagopalan S, Balasubramanian MK (2002) Schizosaccharomyces pombe Birlp, a nuclear protein that localizes to kinetochores and the spindle midzone, is essential for chromosome condensation and spindle elongation during mitosis. Genetics 160: 445-456.
41. Rea S, Eisenhaber F, O'Carroll D et al. (2000) Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406: 593-599.
42. Rudert F, Bronner S, Garnier JM et al. (1995) Transcripts from opposite strands of gamma satellite DNA are differentially expressed during mouse development. Mamm Genome 6: 76-83.
43. Saitoh S, Takahashi K, Yanagida M (1997) Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell 90: 131-143.
44. Schramke V, Allshire R (2003) Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science 301: 1069-1074.
45. Shankaranarayana GD, Motamedi MR, Moazed D et al. (2003) Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast. Curr Biol 13: 1240-1246.
46. Silverstein RA, Ekwall K (2003) Similar mechanisms drive centromeric silencing and gene repression. Cell Cycle 2: 73-75.
47. Silverstein RA, Richardson W, Levin H et al. (2003) A new role for the transcriptional corepressor SIN3; regulation of centromeres. Curr Biol 13: 68-72.
48. Takahashi K, Chen ES, Yanagida M (2000) Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science 288: 2215-2219.
49. Verdel A, Jia S, Gerber S et al. (2004) RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303: 672-676.
50. Volpe TA, Kidner C, Hall IM et al. (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297: 1833-1837.
51. Volpe T, Schramke V, Hamilton GL et al. (2003) RNA interference is required for normal centromere function in fission yeast. Chromosome Res 11: 137-146.
52. Zamore PD, Tuschl T, Sharp PA et al. (2000) RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33.