Enzyme redesign

Chemical Reviews

Volumn 101, Issue 10, 2001, Pages 3027-3046

  Penning, Trevor M ^a   Jez, Joseph M ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGANDS;

CHEMICAL REACTIONS; DNA; MUTAGENESIS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ENZYMES;

ADENOSINE TRIPHOSPHATE; DRUG DERIVATIVE; ENZYME; HYDROLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PROTEIN; TRANSFERASE;

BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COENZYME; COMPUTER AIDED DESIGN; DIRECTED MOLECULAR EVOLUTION; DRUG DESIGN; ENZYME ACTIVATION; ENZYME SPECIFICITY; FACTUAL DATABASE; GENETICS; METABOLISM; MUTAGENESIS; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; REVIEW; STEREOISOMERISM;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CATALYSIS; COENZYMES; COMPUTER-AIDED DESIGN; DATABASES, FACTUAL; DIRECTED MOLECULAR EVOLUTION; DRUG DESIGN; ENZYME ACTIVATION; ENZYMES; HYDROLASES; MOLECULAR STRUCTURE; MUTAGENESIS; NAD; NADP; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEINS; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRANSFERASES;

EID: 0035471134     PISSN: 00092665     EISSN: None     Source Type: Journal    
DOI: 10.1021/cr000049n     Document Type: Review

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