Redesign of substrate-selectivity determining modules of glutathione transferase A1-1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 17, 2000, Pages 9408-9412

  Nilsson, Lisa O ^a   Gustafsson, Ann ^a   Mannervik, Bengt ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Hydroxyalkenal; Protein redesign; Sequential design

Indexed keywords

GLUTATHIONE TRANSFERASE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE MUTATION; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ESCHERICHIA COLI; FELIS CATUS;

EID: 0034662931     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.150084897     Document Type: Article

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