Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 16, 1999, Pages 8949-8954

  Kuroki, Ryota ^a   Weaver, Larry H ^b   Matthews, Brian W ^b  

^a KIRIN BREWERY CO LTD   (Japan)

^b UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CYSTEINE; EGG WHITE; GLUTAMIC ACID; GLYCOSIDASE; HISTIDINE; LYSOZYME; THREONINE;

ARTICLE; BACTERIOPHAGE T4; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIOPHAGE T4; BINDING SITES; CARBOHYDRATE SEQUENCE; GLYCOSIDE HYDROLASES; GLYCOSYLATION; HISTIDINE; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURAMIDASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN ENGINEERING; THREONINE;

EID: 0033529853     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.16.8949     Document Type: Article

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