Conversion of a β-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

Biochemistry

Volumn 38, Issue 36, 1999, Pages 11643-11650

  Witkowski, Andrzej ^a   Joshi, Anil K ^a   Lindqvist, Ylva ^b   Smith, Stuart ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; CARBOXYLYASE; CYSTEINE; FATTY ACID; FATTY ACID SYNTHASE; GLUTAMINE; MALONYL COENZYME A; POLYKETIDE; SYNTHETASE;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; LEPIDOPTERA; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BINDING SITES; CARBOXY-LYASES; CATALYSIS; CYSTEINE; DNA, COMPLEMENTARY; ENZYME INDUCTION; GLUTAMINE; HUMANS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; ESCHERICHIA COLI; LEPIDOPTERA;

EID: 0033533388     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990993h     Document Type: Article

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