Thioesterase domain of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase: Alteration of stereospecificity by site-directed mutagenesis

Journal of Molecular Biology

Volumn 297, Issue 2, 2000, Pages 395-408

  Kallow, Wibke ^a   Kennedy, Jonathan ^b   Arezi, Bahram ^b   Turner, Geoffrey ^a   Von Döhren, Hans ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Biosynthesis; Mutagenesis; Peptide synthetase; Stereospecificity; Thioesterase

Indexed keywords

DELTA(LEVO ALPHA AMINOADIPYL)LEVO CYSTEINYL DEXTRO VALINE SYNTHETASE; GENE PRODUCT; PENICILLIN DERIVATIVE; SYNTHETASE; THIOL ESTER HYDROLASE; TRIPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS NIDULANS; BIOASSAY; DRUG SYNTHESIS; ENZYME ANALYSIS; ENZYME PURIFICATION; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY;

EID: 0034708335     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3566     Document Type: Article

References (38)

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