The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3α-hydroxysteroid dehydrogenase, a representative aldo-keto reductase

Biochemistry

Volumn 38, Issue 24, 1999, Pages 7856-7864

  Ratnam, Kapila ^a   Ma, Haiching ^a   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXYSTEROID DEHYDROGENASE; ARGININE; LIVER ENZYME; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRYPTOPHAN;

ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME KINETICS; FLUORESCENCE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT;

3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC); 3-HYDROXYSTEROID DEHYDROGENASES; ALCOHOL OXIDOREDUCTASES; ANIMALS; ARGININE; BINDING SITES; ELECTROSTATICS; KINETICS; LIVER; METHIONINE; MUTAGENESIS, SITE-DIRECTED; NAD; NADP; OXIDATION-REDUCTION; RATS; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; TIME FACTORS; TRYPTOPHAN;

ANIMALIA; FELIS CATUS;

EID: 0033564742     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982838t     Document Type: Article

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