Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues

Journal of Biological Chemistry

Volumn 274, Issue 4, 1999, Pages 2344-2349

  Oue, Shinya ^a   Okamoto, Akihiro ^a   Yano, Takato ^a   Kagamiyama, Hiroyuki ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ASPARTATE AMINOTRANSFERASES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; VALINE;

FELIS CATUS;

EID: 0033593453     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.4.2344     Document Type: Article

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