Retention of NADPH-linked quinone reductase activity in an Aldo-Keto reductase following mutation of the catalytic tyrosine

Biochemistry

Volumn 37, Issue 31, 1998, Pages 11003-11011

  Schlegel, Brian P ^a,b   Ratnam, Kapila ^a   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

3-HYDROXYSTEROID DEHYDROGENASES; ALCOHOL OXIDOREDUCTASES; ANIMALS; CATALYSIS; ENERGY TRANSFER; ENZYME ACTIVATION; HYDROGEN-ION CONCENTRATION; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; NAD(P)H DEHYDROGENASE (QUINONE); NADP; OXIDATION-REDUCTION; PHENANTHRENES; RATS; SUBSTRATE SPECIFICITY; TYROSINE;

FELIS CATUS;

EID: 0032483038     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980475r     Document Type: Article

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