Redesigning secondary structure to invert coenzyme specificity in isopropylmalate dehydrogenase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 22, 1996, Pages 12171-12176

  Chen, Ridong ^a   Greer, Ann ^a   Dean, Antony M ^a  

^a The Chicago Medical College   (United States)

Author keywords

NAD; NADP; protein engineering; specificity

Indexed keywords

COENZYME A; MALATE DEHYDROGENASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME SPECIFICITY; GENETIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; THERMUS THERMOPHILUS;

THERMUS THERMOPHILUS;

EID: 0030002725     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.22.12171     Document Type: Article

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