Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 4, 1996, Pages 1683-1688

  Kopan, Raphael ^a   Schroeter, Eric H ^a   Weintraub, Harold ^b   Nye, Jeffrey S ^c  

^a WASHINGTON UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPASTATIN; CHLORAMPHENICOL ACETYLTRANSFERASE; MUTANT PROTEIN; PROTEINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEINASE INHIBITION; SIGNAL TRANSDUCTION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL COMPARTMENTATION; CELL DIFFERENTIATION; CELL NUCLEUS; ENDOPEPTIDASES; LEUPEPTINS; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUSCLES; MUTAGENESIS, SITE-DIRECTED; MYOD PROTEIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; RECOMBINANT FUSION PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; XENOPUS;

EID: 0030003538     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.4.1683     Document Type: Article

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