Cell surface presenilin-1 participates in the γ-secretase-like proteolysis of Notch

Journal of Biological Chemistry

Volumn 274, Issue 51, 1999, Pages 36801-36807

  Ray, William J ^a   Yao, Min ^a   Mumm, Jeff ^a   Schroeter, Eric H ^a   Saftig, Paul ^b   Wolfe, Michael ^c   Selkoe, Dennis J ^c   Kopan, Raphael ^a   Goate, Alison M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GAMMA SECRETASE; NOTCH RECEPTOR; PRESENILIN 1;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME MECHANISM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; ENDOPEPTIDASES; HUMANS; MEMBRANE PROTEINS; MICE; MUTATION; PRESENILIN-1; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0033579505     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.51.36801     Document Type: Article

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