The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

Nature Medicine

Volumn 2, Issue 10, 1996, Pages 1146-1150

  Lemere, Cynthia A ^a   Lopera, Francisco ^b   Kosik, Kenneth S ^a   Lendon, Corrine L ^c   Ossa, Jorge ^b   Saido, Takaomi C ^d   Yamaguchi, Haruyasu ^e   Ruiz, Andres ^b   Martinez, Alonso ^b   Madrigal, Lucia ^b   Hincapie, Liliana ^b   Arango L , Juan Carlos ^b   Anthony, Douglas C ^f   Koo, Edward H ^a,f   Goate, Alison M ^c   Selkoe, Dennis J ^a   Arango V , Juan Carlos ^b  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^e GUNMA UNIVERSITY   (Japan)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; PRESENILIN 1;

ALZHEIMER DISEASE; ARTICLE; CEREBELLUM DISEASE; CLINICAL ARTICLE; HUMAN; HUMAN TISSUE; MUTATION; PRIORITY JOURNAL;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BRAIN CHEMISTRY; CEREBELLUM; CODON; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; NEUROFIBRILLARY TANGLES; POINT MUTATION; PRESENILIN-1;

EID: 16044365171     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1096-1146     Document Type: Article

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