Neurotoxicity induces cleavage of p35 to p25 by calpain

Nature

Volumn 405, Issue 6784, 2000, Pages 360-364

  Lee, Ming Sum ^a   Kwon, Young T ^a   Li, Mingwel ^b   Peng, Junmin ^a   Friedlander, Robert M ^b   Tsai, Li Huei ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM; CALPAIN; CYSTEINE PROTEINASE; PROTEIN DERIVATIVE; PROTEIN P35;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL DEATH; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GENE SEQUENCE; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CALCIUM; CALPAIN; CELLS, CULTURED; EGTAZIC ACID; GLUTAMIC ACID; HYDROGEN PEROXIDE; IONOMYCIN; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0034682414     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35012636     Document Type: Article

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