Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid β-protein generation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 16, 2000, Pages 9299-9304

  Xia, Weiming ^a,c   Ray, William J ^b   Ostaszewski, Beth L ^a   Rahmati, Talat ^a   Kimberly, W Taylor ^a   Wolfe, Michael S ^a   Zhang, Jimin ^a   Goate, Alison M ^b   Selkoe, Dennis J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ASPARTATE AMMONIA LYASE; GALACTOSYLTRANSFERASE; GAMMA SECRETASE; PRESENILIN 1;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GOLGI COMPLEX; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; STEADY STATE; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CHO CELLS; CRICETINAE; ENDOPEPTIDASES; GOLGI APPARATUS; HUMANS; HYDROLYSIS; MEMBRANE PROTEINS; PEPTIDE FRAGMENTS; PRESENILIN-1;

ANIMALIA;

EID: 0034255029     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.16.9299     Document Type: Article

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