Characterization of Drosophila Presenilin and its colocalization with Notch during development

Mechanisms of Development

Volumn 79, Issue 1-2, 1998, Pages 199-211

  Ye, Yihong ^a   Fortini, Mark E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Alzheimer's disease; Drosophila; Notch receptor; Presenilin; Subcellular localization

Indexed keywords

PRESENILIN 1;

ARTICLE; CELLULAR DISTRIBUTION; DROSOPHILA; EMBRYO DEVELOPMENT; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; OOGENESIS; PRESENILINS; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS;

CAENORHABDITIS ELEGANS; HEXAPODA;

EID: 0032440973     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(98)00169-5     Document Type: Article

References (35)

1. Berezovska, O., Xia, M., Page, K., Wasco, W., Tanzi, R.E., Hyman, B.T., 1997. Developmental regulation of Presenilin mRNA expression parallels Notch expression. J. Neuropathol. Exp. Neurol. 56, 40-44.
2. Bier, E., Ackerman, L., Barbel, S., Jan, L., Jan, Y.N., 1988. Identification and characterization of a neuron-specific nuclear antigen in Drosophila. Science 240, 913-916.
3. Blaumueller, C.M., Qi, H., Zagouras, P., Artavanis-Tsakonas, S., 1997. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90, 281-291.
4. Boulianne, G.L., Livne-Bar, I., Humphreys, J.M., Liang, Y., Lin, C., Rogaev, E., St. George-Hyslop, P., 1997. Cloning and characterization of the Drosophila Presenilin homologue. Neuroreport 8, 1025-1029.
5. Brand, A., Perrimon, N., 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
6. Cook, D.G., Sung, J.C., Golde, T.E., Felsenstein, K.M., Wojczyk, B.S., Tanzi, R.E., Trojanowski, J.Q., Lee, V.M.-Y., Doms, R.W., 1996. Expression and analysis of Presenilin 1 in a human neuronal system: localization in cell bodies and dendrites. Proc. Natl. Acad. Sci. USA 93, 9223-9228.
7. Culvenor, J.G., Maher, F., Evin, G., Malchiodi-Albedi, F., Cappai, R., Underwood, J.R., Davis, J.B., Karran, E.H., Roberts, G.W., Beyreuther, K., Masters, C.L., 1997. Alzheimer's disease-associated Presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment. J. Neurosci. Res. 49, 719-731.
8. Deng, G., Pike, C.J., Cotman, C.W., 1996. Alzheimer-associated Presenilin-2 confers increased sensitivity to apoptosis in PC12 cells. FEBS Lett. 397, 50-54.
9. De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., Leuven, F.V., 1998. Deficiency of Presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391, 387-390.
10. Dewji, N.N., Singer, S.J., 1997. Cell surface expression of the Alzheimer disease-related Presenilin proteins. Proc. Natl. Acad. Sci. USA 94, 9926-9931.
11. Doan, A., Thinakaran, G., Borchelt, D.R., Slunt, H.H., Ratovitsky, T., Podlisny, M., Selkoe, D.J., Seeger, M., Gandy, S.E., Price, D.L., Sisodia, S.S., 1996. Protein topology of Presenilin 1. Neuron 17, 1023-1030.
12. Fehon, R.G., Kooh, P.J., Rebay, I., Regan, C.L., Xu, T., Muskavitch, M.A.T., Artavanis-Tsakonas, S., 1990. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
13. Fehon, R.G., Johansen, K., Rebay, I., Artavanis-Tsakonas, S., 1991. Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell. Biol. 113, 657-669.
14. Fehon, R.G., Dawson, I.A., Artavanis-Tsakonas, S., 1994. A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. Development 120, 545-557.
15. FlyBase, 1998. FlyBase: the Drosophila genetic database (http//flybase.-bio.indiana.edu/). Nucleic Acids Res. 26, 85-88.
16. Haass, C., 1997. Presenilins: genes for life and death. Neuron 18, 687-690.
17. Hong, C.S., Koo, E.H., 1997. Isolation and characterization of Drosophila Presenilin homolog. Neuroreport 8, 665-668.
18. Janicki, S., Monteiro, M.J., 1997. Increased apoptosis arising from increased expression of the Alzheimer's disease-associated Presenilin-2 mutation (N141I). J. Cell Biol. 139, 485-495.
19. Kopan, R., Schroeter, E.H., Weintraub, H., Nye, J.S., 1996. Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl. Acad. Sci. USA 93, 1683-1688.
20. Kooh, P.J., Fehon, R.G., Muskavitch, M.A.T., 1993. Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 493-507.
21. Kovacs, D.M., Fausett, H.J., Page, K.J., Kim, T.-W., Mori, R.D., Merriam, D.E., Hollister, R.D., Hallmark, O.G., Mancini, R., Felsenstein, K.M., Hyman, B.T., Tanzi, R.E., Wasco, W., 1996. Alzheimer-associated Presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med. 2, 224-229.
22. Levitan, D., Greenwald, I., 1995. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351-354.
23. Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., Yu, C., Jondro, P.D., Schmidt, S.D., Wang, K., Crowley, A.C., Fu, Y.-H., Guenette, S.Y., Galas, D., Nemens, E., Wijsman, E.M., Bird, T.D., Schellenberg, G.D., Tanzi, R.E., 1995. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973-977.
24. Li, J., Xu, M., Zhou, H., Ma, J., Potter, H., 1997. Alzheimer Presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation. Cell 90, 917-927.
25. Li, X., Greenwald, I., 1997. HOP-1, a Caenorhabditis elegans Presenilin, appears to be functionally redundant with SEL-12 Presenilin and to facilitate LIN-12 and GLP-1 signaling. Proc. Natl. Acad. Sci. USA 94, 12204-12209.
26. Pan, D., Rubin, G.M., 1997. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell 90, 271-280.
27. Rogaev, E.I., Sherrington, R., Rogaeva, E.A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T., Mar, L., Sorbi, S., Nacmias, B., Piacentini, S., Amaducci, L., Chumakov, I., Cohen, D., Lannfelt, L., Fraser, P.E., Rommens, J.M., St. George-Hyslop, P.H., 1995. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775-778.
28. Schroeter, E.H., Kisslinger, J.A., Kopan, R., 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393, 382-386.
29. Selkoe, D.J., 1996. Amyloid β-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271, 18295-18298.
30. Sherrington, R., Rogaev, E.I., Liang, Y., Rogaeva, E.A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., Tsuda, T., Mar, L., Foncin, J.-F., Bruni, A.C., Montesi, M.P., Sorbi, S., Rainero, I., Pinessi, L., Nee, L., Chumakov, I., Pollen, D., Brookes, A., Sanseau, P., Polinsky, R.J. et al. , 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760.
31. Struhl, G., Adachi, A., 1998. Nuclear access and action of Notch in vivo. Cell 93, 649-660.
32. Thummel, C.S., Pirrotta, V., 1992. New pCaSpeR P element vectors. Dros. Inf. Serv. 71, 150.
33. Vito, P., Ghayur, T., D'Adamio, L., 1997. Generation of anti-apoptotic Presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage. J. Biol. Chem. 272, 28315-28320.
34. Wolozin, B., Iwasaki, K., Vito, P., Ganjei, J.K., Lacanà, E., Sunderland, T., Zhao, B., Kusiak, J.W., Wasco, W., D'Adamio, L., 1996. Participation of Presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science 274, 1710-1713.
35. Wong, P.C., Zheng, H., Chen, H., Becher, M.W., Sirinathsinghji, D.J.S., Trambauer, M.E., Chen, H.Y., Price, D.L., Van de Ploeg, L.H.T., Sisodia, S.S., 1997. Presenilin 1 is required for Notch1 and Dll1 expression in the paraxial mesoderm. Nature 387, 288-292.