The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 5, 1997, Pages 2025-2030

  Tomita, Taisuke ^a,b   Maruyama, Kei ^a   Saido, Takaomi C ^c   Kume, Hideaki ^a   Shinozaki, Kohki ^a   Tokuhiro, Shinya ^b   Capell, Anja ^d   Walter, Jochen ^d   Grünberg, Jürgen ^d   Haass, Christian ^d   Iwatsubo, Takeshi ^b   Obata, Kunihiko ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; POLYPEPTIDE; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; CELL STRAIN COS1; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FAMILIAL DISEASE; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SECRETION;

ANIMALIA;

EID: 12644258498     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.5.2025     Document Type: Article

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